SG11202109191SA - Macrocyclic compounds as sting agonists - Google Patents
Macrocyclic compounds as sting agonistsInfo
- Publication number
- SG11202109191SA SG11202109191SA SG11202109191SA SG11202109191SA SG11202109191SA SG 11202109191S A SG11202109191S A SG 11202109191SA SG 11202109191S A SG11202109191S A SG 11202109191SA SG 11202109191S A SG11202109191S A SG 11202109191SA SG 11202109191S A SG11202109191S A SG 11202109191SA
- Authority
- SG
- Singapore
- Prior art keywords
- macrocyclic compounds
- sting agonists
- sting
- agonists
- macrocyclic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/16—Peri-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/537—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines spiro-condensed or forming part of bridged ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN201921012258 | 2019-03-28 | ||
IN201921046194 | 2019-11-13 | ||
PCT/IB2020/052654 WO2020194160A1 (en) | 2019-03-28 | 2020-03-21 | Macrocyclic compounds as sting agonists |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202109191SA true SG11202109191SA (en) | 2021-09-29 |
Family
ID=70293003
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202109191SA SG11202109191SA (en) | 2019-03-28 | 2020-03-21 | Macrocyclic compounds as sting agonists |
Country Status (19)
Country | Link |
---|---|
US (1) | US20220144852A1 (en) |
EP (1) | EP3946610A1 (en) |
JP (1) | JP2022527306A (en) |
KR (1) | KR20210146370A (en) |
CN (1) | CN113631228B (en) |
AU (1) | AU2020245263A1 (en) |
BR (1) | BR112021018947A2 (en) |
CA (1) | CA3132508A1 (en) |
CL (1) | CL2021002480A1 (en) |
CO (1) | CO2021012559A2 (en) |
CR (1) | CR20210495A (en) |
EC (1) | ECSP21071644A (en) |
IL (1) | IL286526A (en) |
MA (1) | MA55517A (en) |
MX (1) | MX2021011686A (en) |
PE (1) | PE20220169A1 (en) |
SG (1) | SG11202109191SA (en) |
WO (1) | WO2020194160A1 (en) |
ZA (1) | ZA202106629B (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA3147397A1 (en) * | 2019-07-22 | 2021-01-28 | Lupin Limited | Macrocyclic compounds as sting agonists and methods and uses thereof |
JP2022543086A (en) | 2019-08-02 | 2022-10-07 | メルサナ セラピューティクス インコーポレイテッド | Bis-[N-((5-carbamoyl)-1H-benzo[d]imidazol-2-yl)-pyrazole-5-carboxamide] derivatives as STING (interferon gene stimulator) agonists for the treatment of cancer and related Compound |
EP4134098A4 (en) | 2020-04-10 | 2024-05-15 | Ono Pharmaceutical Co | Method of cancer therapy |
JP2024503508A (en) * | 2021-01-15 | 2024-01-25 | シージェン インコーポレイテッド | Immunomodulatory antibody-drug conjugates |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104513253A (en) * | 2013-10-01 | 2015-04-15 | 南京波尔泰药业科技有限公司 | Macrocyclic compounds for the treatment of proliferative diseases |
JP6835727B2 (en) * | 2015-02-05 | 2021-02-24 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung | Macrocycles and their use as IRAK1 / 4 inhibitors |
CA3030582A1 (en) | 2015-07-22 | 2017-01-26 | The Royal Institution For The Advancement Of Learning/Mcgill University | Compounds and uses thereof in the treatment of cancers and other medical conditions |
AR107032A1 (en) | 2015-12-09 | 2018-03-14 | Padlock Therapeutics Inc | PAD4 BICYCLIC INHIBITORS |
CR20200045A (en) * | 2016-04-07 | 2020-03-11 | Glaxosmithkline Ip Dev Ltd | Heterocyclic amides useful as protein modulators |
EP3440072B1 (en) | 2016-04-07 | 2020-01-29 | GlaxoSmithKline Intellectual Property Development Ltd | Heterocyclic amides useful as protein modulators |
US20200138827A1 (en) | 2017-06-22 | 2020-05-07 | Curadev Pharma Limited | Small molecule modulators of human sting |
UA125730C2 (en) | 2017-06-22 | 2022-05-25 | Курадев Фарма Лімітед | Small molecule modulators of human sting |
JP2020524718A (en) | 2017-06-22 | 2020-08-20 | キュラデブ・ファーマ・リミテッドCuradev Pharma Limited | Heterocyclic small molecule regulator of human STING |
EP3658138B1 (en) | 2017-07-27 | 2023-04-19 | Stingray Therapeutics, Inc. | Substituted-3h-imidazo(4,5-c)pyridine and 1h-pyrrolo(2,3-c)pyridine series of novel ectonucleotide pyrophsphatase/phosphodiestrase-1 (enpp1) and stimulator for interferon genes (sting) modulator as cancer immunotherapeutics |
AU2018311965A1 (en) * | 2017-08-04 | 2020-02-13 | Merck Sharp & Dohme Llc | Combinations of PD-1 antagonists and benzo[b]thiophene sting antagonists for cancer treatment |
MA49772A (en) | 2017-08-04 | 2021-04-21 | Merck Sharp & Dohme | STING THIOPHENE BENZO [B] AGONISTS FOR CANCER TREATMENT |
-
2020
- 2020-03-21 PE PE2021001577A patent/PE20220169A1/en unknown
- 2020-03-21 MA MA055517A patent/MA55517A/en unknown
- 2020-03-21 KR KR1020217035108A patent/KR20210146370A/en unknown
- 2020-03-21 WO PCT/IB2020/052654 patent/WO2020194160A1/en active Application Filing
- 2020-03-21 CN CN202080025785.1A patent/CN113631228B/en active Active
- 2020-03-21 US US17/598,524 patent/US20220144852A1/en active Pending
- 2020-03-21 EP EP20719719.5A patent/EP3946610A1/en active Pending
- 2020-03-21 MX MX2021011686A patent/MX2021011686A/en unknown
- 2020-03-21 JP JP2021557830A patent/JP2022527306A/en active Pending
- 2020-03-21 BR BR112021018947A patent/BR112021018947A2/en unknown
- 2020-03-21 CR CR20210495A patent/CR20210495A/en unknown
- 2020-03-21 CA CA3132508A patent/CA3132508A1/en active Pending
- 2020-03-21 SG SG11202109191SA patent/SG11202109191SA/en unknown
- 2020-03-21 AU AU2020245263A patent/AU2020245263A1/en active Pending
-
2021
- 2021-09-08 ZA ZA2021/06629A patent/ZA202106629B/en unknown
- 2021-09-19 IL IL286526A patent/IL286526A/en unknown
- 2021-09-24 EC ECSENADI202171644A patent/ECSP21071644A/en unknown
- 2021-09-24 CL CL2021002480A patent/CL2021002480A1/en unknown
- 2021-09-24 CO CONC2021/0012559A patent/CO2021012559A2/en unknown
Also Published As
Publication number | Publication date |
---|---|
US20220144852A1 (en) | 2022-05-12 |
ZA202106629B (en) | 2022-07-27 |
CA3132508A1 (en) | 2020-10-01 |
CO2021012559A2 (en) | 2021-09-30 |
PE20220169A1 (en) | 2022-01-28 |
IL286526A (en) | 2021-10-31 |
WO2020194160A1 (en) | 2020-10-01 |
AU2020245263A1 (en) | 2021-10-07 |
JP2022527306A (en) | 2022-06-01 |
KR20210146370A (en) | 2021-12-03 |
CR20210495A (en) | 2021-10-18 |
CN113631228B (en) | 2023-10-13 |
CL2021002480A1 (en) | 2022-04-29 |
CN113631228A (en) | 2021-11-09 |
MX2021011686A (en) | 2021-10-22 |
MA55517A (en) | 2022-02-09 |
BR112021018947A2 (en) | 2022-02-08 |
EP3946610A1 (en) | 2022-02-09 |
ECSP21071644A (en) | 2021-12-30 |
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