US4522811A
(en)
|
1982-07-08 |
1985-06-11 |
Syntex (U.S.A.) Inc. |
Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
|
US20070208082A1
(en)
|
2005-08-10 |
2007-09-06 |
John Hopkins University |
Polyamines useful as anti-parasitic and anti-cancer therapeutics and as lysine-specific demethylase inhibitors
|
US20110092601A1
(en)
|
2007-04-13 |
2011-04-21 |
The Johns Hopkins University |
Lysine-specific demethylase inhibitors
|
WO2010043721A1
(en)
|
2008-10-17 |
2010-04-22 |
Oryzon Genomics, S.A. |
Oxidase inhibitors and their use
|
WO2010084160A1
(en)
|
2009-01-21 |
2010-07-29 |
Oryzon Genomics S.A. |
Phenylcyclopropylamine derivatives and their medical use
|
US8389580B2
(en)
|
2009-06-02 |
2013-03-05 |
Duke University |
Arylcyclopropylamines and methods of use
|
WO2010143582A1
(en)
|
2009-06-11 |
2010-12-16 |
公立大学法人名古屋市立大学 |
Phenylcyclopropylamine derivatives and lsd1 inhibitors
|
US9708255B2
(en)
|
2009-08-18 |
2017-07-18 |
Robert A. Casero |
(bis)urea and (bis)thiourea compounds as epigenic modulators of lysine-specific demethylase 1 and methods of treating disorders
|
CA2812683C
(en)
|
2009-09-25 |
2017-10-10 |
Oryzon Genomics S.A. |
Lysine specific demethylase-1 inhibitors and their use
|
EP2486002B1
(en)
|
2009-10-09 |
2019-03-27 |
Oryzon Genomics, S.A. |
Substituted heteroaryl- and aryl- cyclopropylamine acetamides and their use
|
BR112012026694A2
(en)
|
2010-04-19 |
2016-07-12 |
Oryzon Genomics Sa |
lysine 1-specific demethylase inhibitors and their use
|
EA022459B1
(en)
|
2010-04-20 |
2016-01-29 |
Университа' Дельи Студи Ди Рома "Ла Сапиенца" |
Tranylcypromine derivatives as inhibitors of histone demethylase lsd1 and/or lsd2
|
WO2012013727A1
(en)
|
2010-07-29 |
2012-02-02 |
Oryzon Genomics S.A. |
Cyclopropylamine derivatives useful as lsd1 inhibitors
|
SI2598482T1
(en)
|
2010-07-29 |
2018-09-28 |
Oryzon Genomics, S.A. |
Arylcyclopropylamine based demethylase inhibitors of lsd1 and their medical use
|
US9527805B2
(en)
|
2010-09-10 |
2016-12-27 |
Robert A. Casero |
Small molecules as epigenetic modulators of lysine-specific demethylase 1 and methods of treating disorders
|
WO2012045883A1
(en)
|
2010-10-08 |
2012-04-12 |
Oryzon Genomics S.A. |
Cyclopropylamine inhibitors of oxidases
|
WO2012071469A2
(en)
|
2010-11-23 |
2012-05-31 |
Nevada Cancer Institute |
Histone demethylase inhibitors and uses thereof for treatment o f cancer
|
SG193241A1
(en)
|
2011-03-25 |
2013-10-30 |
Glaxosmithkline Ip No 2 Ltd |
Cyclopropylamines as lsd1 inhibitors
|
KR20140052018A
(en)
|
2011-08-09 |
2014-05-02 |
다케다 야쿠힌 고교 가부시키가이샤 |
Cyclopropaneamine compound
|
JP6122006B2
(en)
|
2011-08-15 |
2017-04-26 |
ザ ユニバーシティ オブ ユタ リサーチ ファウンデイション |
Substituted (E) -N '-(1-phenylethylidene) benzohydrazide analogs as histone demethylase inhibitors
|
US9289415B2
(en)
|
2011-09-01 |
2016-03-22 |
The Brigham And Women's Hospital, Inc. |
Treatment of cancer
|
BR112014009238B1
(en)
|
2011-10-20 |
2022-08-09 |
Oryzon Genomics S.A. |
(HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS, THEIR USES AND PHARMACEUTICAL COMPOSITIONS
|
JP6215212B2
(en)
|
2011-10-20 |
2017-10-18 |
オリゾン・ジェノミックス・ソシエダッド・アノニマOryzon Genomics S.A. |
(Hetero) arylcyclopropylamine compounds as LSD1 inhibitors
|
US9751885B2
(en)
|
2012-10-12 |
2017-09-05 |
Takeda Pharmaceutical Company Limited |
Cyclopropanamine compound and use thereof
|
EP2927212A4
(en)
|
2012-11-28 |
2016-06-08 |
Univ Kyoto |
Lsd1-selective inhibitor having lysine structure
|
EP2925307B1
(en)
|
2012-11-30 |
2020-10-28 |
McCord, Darlene E. |
Hydroxytyrosol and oleuropein compositions for induction of dna damage, cell death and lsd1 inhibition
|
EP2740474A1
(en)
|
2012-12-05 |
2014-06-11 |
Instituto Europeo di Oncologia S.r.l. |
Cyclopropylamine derivatives useful as inhibitors of histone demethylases kdm1a
|
CN103054869A
(en)
|
2013-01-18 |
2013-04-24 |
郑州大学 |
Application of amino dithio formic ester compound with triazolyl in preparing medicine taking LSD1 (Lysine Specificity Demethylase 1) as target
|
WO2014164867A1
(en)
|
2013-03-11 |
2014-10-09 |
Imago Biosciences |
Kdm1a inhibitors for the treatment of disease
|
SG11201510376QA
(en)
|
2013-06-19 |
2016-01-28 |
Univ Utah Res Found |
Substituted (e)-n'-(1-phenylethylidene) benzohydrazide analogs as histone demethylase inhibitors
|
CN103319466B
(en)
|
2013-07-04 |
2016-03-16 |
郑州大学 |
Containing the 1,2,3-triazoles-dithiocarbamates compound of tonka bean camphor parent nucleus, preparation method and application thereof
|
NZ716427A
(en)
|
2013-08-06 |
2021-07-30 |
Imago Biosciences Inc |
Kdm1a inhibitors for the treatment of disease
|
US9186391B2
(en)
|
2013-08-29 |
2015-11-17 |
Musc Foundation For Research Development |
Cyclic peptide inhibitors of lysine-specific demethylase 1
|
US9556170B2
(en)
|
2013-08-30 |
2017-01-31 |
University Of Utah Research Foundation |
Substituted-1H-benzo[d]imidazole series compounds as lysine-specific demethylase 1 (LSD1) inhibitors
|
WO2015089192A1
(en)
|
2013-12-11 |
2015-06-18 |
Quanticel Pharmaceuticals, Inc. |
Inhibitors of lysine specific demethylase-1
|
EP3102034A4
(en)
|
2014-02-07 |
2017-07-12 |
MUSC Foundation For Research Development |
Aminotriazole- and aminotetrazole-based kdm1a inhibitors as epigenetic modulators
|
EP3626713B1
(en)
|
2014-02-13 |
2021-09-29 |
Incyte Corporation |
Cyclopropylamines for use as lsd1 inhibitors
|
EP3392244A1
(en)
|
2014-02-13 |
2018-10-24 |
Incyte Corporation |
Cyclopropylamines as lsd1 inhibitors
|
US9527835B2
(en)
|
2014-02-13 |
2016-12-27 |
Incyte Corporation |
Cyclopropylamines as LSD1 inhibitors
|
CN106488915B
(en)
|
2014-02-13 |
2020-10-02 |
因赛特公司 |
Cyclopropylamines as LSD1 inhibitors
|
EP3114109A4
(en)
|
2014-03-07 |
2017-10-18 |
The Johns Hopkins University |
Inhibitors of histone lysine specific demethylase (lsd1) and histone deacetylases (hdacs)
|
CN103893163B
(en)
|
2014-03-28 |
2016-02-03 |
中国药科大学 |
The application of 2-([1,1 '-biphenyl]-4-base) 2-oxoethyl 4-((the chloro-4-aminomethyl phenyl of 3-) is amino)-4-oxobutanoic acid esters in preparation LSD1 inhibitor medicaments
|
MY180575A
(en)
|
2014-04-11 |
2020-12-02 |
Takeda Pharmaceuticals Co |
Cyclopropanamine compound and use thereof
|
CN103961340B
(en)
|
2014-04-30 |
2019-06-25 |
南通中国科学院海洋研究所海洋科学与技术研究发展中心 |
A kind of LSD1 inhibitor and its application
|
EP3137169B1
(en)
|
2014-05-01 |
2021-11-10 |
Celgene Quanticel Research, Inc. |
Inhibitors of lysine specific demethylase-1
|
AU2015265820C1
(en)
|
2014-05-30 |
2020-01-16 |
Ieo - Istituto Europeo Di Oncologia S.R.L. |
Cyclopropylamine compounds as histone demethylase inhibitors
|
CN104119280B
(en)
|
2014-06-27 |
2016-03-16 |
郑州大学 |
Containing the pyrimidine derivatives of amino urea and Terminal Acetylenes structural unit, preparation method and application
|
WO2015200843A1
(en)
|
2014-06-27 |
2015-12-30 |
Quanticel Pharmaceuticals, Inc. |
Inhibitors of lysine specific demethylase-1
|
EP3164509B1
(en)
|
2014-07-03 |
2021-12-29 |
Celgene Quanticel Research, Inc. |
Inhibitors of lysine specific demethylase-1
|
EP3511319B1
(en)
|
2014-07-03 |
2023-05-03 |
Celgene Quanticel Research, Inc. |
Inhibitors of lysine specific demethylase-1
|
US9695180B2
(en)
|
2014-07-10 |
2017-07-04 |
Incyte Corporation |
Substituted imidazo[1,2-a]pyrazines as LSD1 inhibitors
|
WO2016007727A1
(en)
|
2014-07-10 |
2016-01-14 |
Incyte Corporation |
Triazolopyridines and triazolopyrazines as lsd1 inhibitors
|
US9695168B2
(en)
|
2014-07-10 |
2017-07-04 |
Incyte Corporation |
Substituted imidazo[1,5-α]pyridines and imidazo[1,5-α]pyrazines as LSD1 inhibitors
|
US9695167B2
(en)
|
2014-07-10 |
2017-07-04 |
Incyte Corporation |
Substituted triazolo[1,5-a]pyridines and triazolo[1,5-a]pyrazines as LSD1 inhibitors
|
EP2993175A1
(en)
|
2014-09-05 |
2016-03-09 |
IEO - Istituto Europeo di Oncologia Srl |
Thienopyrroles as histone demethylase inhibitors
|
AU2015311805B2
(en)
|
2014-09-05 |
2020-04-02 |
Celgene Quanticel Research, Inc. |
Inhibitors of lysine specific demethylase-1
|
EP3250552B1
(en)
|
2015-01-30 |
2019-03-27 |
Genentech, Inc. |
Therapeutic compounds and uses thereof
|
WO2016130952A1
(en)
|
2015-02-12 |
2016-08-18 |
Imago Biosciences, Inc. |
Kdm1a inhibitors for the treatment of disease
|
CN106146361A
(en)
|
2015-03-16 |
2016-11-23 |
四川大学 |
Indenes-1-subunit sulfonyl benzoyl hydrazine derivant and its production and use
|
AU2016243939B2
(en)
|
2015-04-03 |
2020-09-03 |
Incyte Holdings Corporation |
Heterocyclic compounds as LSD1 inhibitors
|
CN106045862B
(en)
|
2015-04-10 |
2019-04-23 |
上海迪诺医药科技有限公司 |
Cyclopropyl amine spiral shell (miscellaneous) cycle compound, its pharmaceutical composition and application
|
EP3286172B1
(en)
|
2015-04-23 |
2019-06-12 |
Constellation Pharmaceuticals, Inc. |
Lsd1 inhibitors and uses thereof
|
EP3090998A1
(en)
|
2015-05-06 |
2016-11-09 |
F. Hoffmann-La Roche AG |
Solid forms
|
WO2017004519A1
(en)
|
2015-07-02 |
2017-01-05 |
University Of Utah Research Foundation |
Substituted benzohydrazide analogs as histone demethylase inhibitors
|
EA035534B1
(en)
|
2015-08-12 |
2020-06-30 |
Инсайт Корпорейшн |
Salts of an lsd1 inhibitor
|
WO2017079476A1
(en)
|
2015-11-05 |
2017-05-11 |
Mirati Therapeutics, Inc. |
Lsd1 inhibitors
|
CN108473442B
(en)
|
2015-11-05 |
2022-03-25 |
赛尔基因昆蒂赛尔研究公司 |
Compositions comprising inhibitors of lysine-specific demethylase-1
|
CA3006434C
(en)
|
2015-11-27 |
2021-03-16 |
Taiho Pharmaceutical Co., Ltd. |
Biphenyl compound or salt thereof
|
WO2017109061A1
(en)
|
2015-12-23 |
2017-06-29 |
Ieo - Istituto Europeo Di Oncologia S.R.L. |
Spirocyclopropylamine derivatives useful as inhibitors of histone demethylases kdm1a
|
CA3009805C
(en)
|
2015-12-29 |
2023-10-17 |
Mirati Therapeutics, Inc. |
Lsd1 inhibitors
|
AU2016382512A1
(en)
|
2015-12-30 |
2018-07-12 |
Novartis Ag |
Immune effector cell therapies with enhanced efficacy
|
US10590079B2
(en)
|
2016-03-01 |
2020-03-17 |
Novartis Ag |
Cyano-substituted indoles as LSD1 inhibitors
|
CN107200706A
(en)
|
2016-03-16 |
2017-09-26 |
中国科学院上海药物研究所 |
Cyclopropylamine class compound of one class fluorine substitution and preparation method thereof, pharmaceutical composition and purposes
|
US20170283397A1
(en)
|
2016-03-31 |
2017-10-05 |
University Of Utah Research Foundation |
Substituted 1-h-indol-3-yl-benzamide and 1, 1'-biphenyl analogs as histone demethylase inhibitors
|
AU2017263361B2
(en)
|
2016-05-09 |
2021-08-05 |
Jubilant Epicore LLC |
Cyclopropyl-amide compounds as dual LSD1/HDAC inhibitors
|
EP3246330A1
(en)
|
2016-05-18 |
2017-11-22 |
Istituto Europeo di Oncologia S.r.l. |
Imidazoles as histone demethylase inhibitors
|
CN107513068A
(en)
|
2016-06-16 |
2017-12-26 |
中国科学院上海药物研究所 |
A kind of new compound and its preparation and application with FGFR inhibitory activity
|
CN106478639B
(en)
|
2016-09-05 |
2018-09-18 |
郑州大学 |
LSD1 inhibitor, preparation method and the application of 1,2,4-triazole of pyrimido
|
CN106432248B
(en)
|
2016-09-27 |
2018-11-27 |
郑州大学 |
The LSD1 of triazole containing pyrimido inhibitor, preparation method and application
|
RS64889B1
(en)
|
2016-10-26 |
2023-12-29 |
Constellation Pharmaceuticals Inc |
Lsd1 inhibitors and medical uses thereof
|
WO2018081342A1
(en)
|
2016-10-26 |
2018-05-03 |
Constellation Pharmaceuticals, Inc. |
Lsd1 inhibitors and uses thereof
|
CN110248926B
(en)
|
2017-01-24 |
2022-12-06 |
石药集团中奇制药技术(石家庄)有限公司 |
LSD1 inhibitor and preparation method and application thereof
|
CN106831489B
(en)
|
2017-03-23 |
2018-04-17 |
郑州大学 |
Tranylcypromine acylhydrazone, preparation method and applications
|
CN106928235A
(en)
|
2017-05-03 |
2017-07-07 |
郑州大学 |
The LSD1 of triazole containing pyrimido inhibitor, its preparation method and application
|
WO2018213211A1
(en)
|
2017-05-15 |
2018-11-22 |
The Regents Of The University Of Michigan |
Pyrrolo[2,3-c]pyridines and related analogs as lsd-1 inhibitors
|
US11479563B2
(en)
|
2017-05-26 |
2022-10-25 |
Taiho Pharmaceutical Co., Ltd. |
Biphenyl compound or salt thereof
|
KR20180134675A
(en)
|
2017-06-09 |
2018-12-19 |
한미약품 주식회사 |
Cyclopropylamine derivative compound and use thereof
|
UY37774A
(en)
|
2017-06-19 |
2019-01-31 |
Novartis Ag |
SUBSTITUTED 5-CYANOINDOL COMPOUNDS AND USES OF THE SAME
|
JP2020152641A
(en)
|
2017-07-07 |
2020-09-24 |
国立研究開発法人理化学研究所 |
Novel compound having lysine-specific demethylating enzyme 1 inhibitory activity, method for producing the same, and use of the same
|
JP2020529995A
(en)
*
|
2017-08-03 |
2020-10-15 |
オリゾン ジェノミックス ソシエダッド アノニマ |
How to treat behavioral changes
|