SG11202105714UA - Anti-igf-i receptor humanized antibody - Google Patents

Anti-igf-i receptor humanized antibody

Info

Publication number
SG11202105714UA
SG11202105714UA SG11202105714UA SG11202105714UA SG11202105714UA SG 11202105714U A SG11202105714U A SG 11202105714UA SG 11202105714U A SG11202105714U A SG 11202105714UA SG 11202105714U A SG11202105714U A SG 11202105714UA SG 11202105714U A SG11202105714U A SG 11202105714UA
Authority
SG
Singapore
Prior art keywords
igf
humanized antibody
receptor humanized
receptor
antibody
Prior art date
Application number
SG11202105714UA
Other languages
English (en)
Inventor
Akira Tanokura
Hirotsugu Kato
Hiroshi Eguchi
Kenichiro Takagi
Satoshi Yamamura
Naoko Namiki
Daisuke Ishikawa
Hirofumi Higuchi
Tomoyo Takeo
Masayo Ohori
Original Assignee
Teijin Pharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Pharma Ltd filed Critical Teijin Pharma Ltd
Publication of SG11202105714UA publication Critical patent/SG11202105714UA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0658Skeletal muscle cells, e.g. myocytes, myotubes, myoblasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/75Agonist effect on antigen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
SG11202105714UA 2018-12-03 2019-12-02 Anti-igf-i receptor humanized antibody SG11202105714UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2018226669 2018-12-03
PCT/JP2019/047050 WO2020116398A1 (fr) 2018-12-03 2019-12-02 Anticorps humanisé anti-récepteur de l'igf-i

Publications (1)

Publication Number Publication Date
SG11202105714UA true SG11202105714UA (en) 2021-06-29

Family

ID=70974206

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202105714UA SG11202105714UA (en) 2018-12-03 2019-12-02 Anti-igf-i receptor humanized antibody

Country Status (19)

Country Link
US (1) US20220033485A1 (fr)
EP (1) EP3895732A4 (fr)
JP (2) JP7246409B2 (fr)
KR (1) KR20210088625A (fr)
CN (1) CN113286612A (fr)
AR (1) AR117673A1 (fr)
AU (1) AU2019393487A1 (fr)
BR (1) BR112021010479A2 (fr)
CA (1) CA3120740A1 (fr)
CL (1) CL2021001446A1 (fr)
CO (1) CO2021007229A2 (fr)
IL (1) IL283099A (fr)
MA (1) MA54464A (fr)
MX (1) MX2021006495A (fr)
PH (1) PH12021551210A1 (fr)
SG (1) SG11202105714UA (fr)
TW (1) TW202039559A (fr)
WO (1) WO2020116398A1 (fr)
ZA (1) ZA202103350B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4159860A1 (fr) * 2020-06-02 2023-04-05 Teijin Pharma Limited Anticorps humanisé de récepteur anti-igf-1

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0302525A2 (hu) * 2001-01-05 2003-10-28 Abgenix, Inc. Az inzulinszerű növekedési faktor I receptor elleni ellenanyagok
US7538195B2 (en) * 2002-06-14 2009-05-26 Immunogen Inc. Anti-IGF-I receptor antibody
FR2888850B1 (fr) * 2005-07-22 2013-01-11 Pf Medicament Nouveaux anticorps anti-igf-ir et leurs applications
ES2388827T3 (es) 2008-04-03 2012-10-19 F. Hoffmann-La Roche Ag Uso de variantes de IGF-I PEGiladas para el tratamiento de trastornos neuromusculares
JP6096267B1 (ja) 2015-12-09 2017-03-15 上銀科技股▲分▼有限公司 ボールねじに用いる防塵ユニット
IL270971B1 (en) * 2017-05-30 2024-02-01 Teijin Pharma Ltd Antibody against the 1-IGF receptor

Also Published As

Publication number Publication date
US20220033485A1 (en) 2022-02-03
WO2020116398A1 (fr) 2020-06-11
MA54464A (fr) 2021-10-20
CL2021001446A1 (es) 2022-01-14
EP3895732A4 (fr) 2022-09-14
KR20210088625A (ko) 2021-07-14
ZA202103350B (en) 2022-08-31
TW202039559A (zh) 2020-11-01
CO2021007229A2 (es) 2021-08-19
JP2023011808A (ja) 2023-01-24
MX2021006495A (es) 2021-07-06
AU2019393487A1 (en) 2021-06-03
CN113286612A (zh) 2021-08-20
CA3120740A1 (fr) 2020-06-11
AR117673A1 (es) 2021-08-25
IL283099A (en) 2021-06-30
JP7246409B2 (ja) 2023-03-27
PH12021551210A1 (en) 2021-11-08
JPWO2020116398A1 (ja) 2021-09-30
BR112021010479A2 (pt) 2021-11-16
EP3895732A1 (fr) 2021-10-20

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