SG11202105403XA - Antibodies specifically recognizing granulocyte-macrophage colony stimulating factor receptor alpha and uses thereof - Google Patents
Antibodies specifically recognizing granulocyte-macrophage colony stimulating factor receptor alpha and uses thereofInfo
- Publication number
- SG11202105403XA SG11202105403XA SG11202105403XA SG11202105403XA SG11202105403XA SG 11202105403X A SG11202105403X A SG 11202105403XA SG 11202105403X A SG11202105403X A SG 11202105403XA SG 11202105403X A SG11202105403X A SG 11202105403XA SG 11202105403X A SG11202105403X A SG 11202105403XA
- Authority
- SG
- Singapore
- Prior art keywords
- granulocyte
- factor receptor
- stimulating factor
- colony stimulating
- macrophage colony
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Crystallography & Structural Chemistry (AREA)
- Virology (AREA)
- Hematology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2018117581 | 2018-11-27 | ||
PCT/CN2019/120545 WO2020108423A1 (en) | 2018-11-27 | 2019-11-25 | Antibodies specifically recognizing granulocyte-macrophage colony stimulating factor receptor alpha and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202105403XA true SG11202105403XA (en) | 2021-06-29 |
Family
ID=70853745
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202105403XA SG11202105403XA (en) | 2018-11-27 | 2019-11-25 | Antibodies specifically recognizing granulocyte-macrophage colony stimulating factor receptor alpha and uses thereof |
Country Status (13)
Country | Link |
---|---|
US (1) | US20230002496A1 (en) |
EP (1) | EP3902835A4 (en) |
JP (2) | JP7290725B2 (en) |
KR (1) | KR102655193B1 (en) |
CN (2) | CN116003597A (en) |
AU (1) | AU2019388584B2 (en) |
BR (1) | BR112021009709A2 (en) |
CA (2) | CA3120729A1 (en) |
EA (1) | EA202191470A1 (en) |
PH (1) | PH12021551195A1 (en) |
SG (1) | SG11202105403XA (en) |
WO (1) | WO2020108423A1 (en) |
ZA (1) | ZA202103596B (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP4263597A2 (en) * | 2020-12-18 | 2023-10-25 | Kiniksa Pharmaceuticals, Ltd. | Protein compositions and methods for producing and using the same |
WO2023138499A1 (en) * | 2022-01-20 | 2023-07-27 | 舒泰神(北京)生物制药股份有限公司 | Antibody preparation for specifically recognizing granulocyte-macrophage colony-stimulating factor receptor and use thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL2423230T3 (en) | 2006-03-27 | 2013-10-31 | Medimmune Ltd | Binding member for GM-CSF receptor |
CN103193882B (en) | 2013-03-29 | 2014-11-05 | 浙江大学 | Embryonic stem cell specific marker GM-CSFR alpha and application thereof |
-
2019
- 2019-11-25 US US17/297,421 patent/US20230002496A1/en active Pending
- 2019-11-25 SG SG11202105403XA patent/SG11202105403XA/en unknown
- 2019-11-25 KR KR1020217019432A patent/KR102655193B1/en active IP Right Grant
- 2019-11-25 EP EP19891384.0A patent/EP3902835A4/en active Pending
- 2019-11-25 BR BR112021009709-0A patent/BR112021009709A2/en unknown
- 2019-11-25 WO PCT/CN2019/120545 patent/WO2020108423A1/en unknown
- 2019-11-25 CN CN202211024107.0A patent/CN116003597A/en active Pending
- 2019-11-25 CN CN201980076356.4A patent/CN113348179A/en active Pending
- 2019-11-25 AU AU2019388584A patent/AU2019388584B2/en active Active
- 2019-11-25 CA CA3120729A patent/CA3120729A1/en active Pending
- 2019-11-25 EA EA202191470A patent/EA202191470A1/en unknown
- 2019-11-25 CA CA3183309A patent/CA3183309A1/en active Pending
- 2019-11-25 JP JP2021529718A patent/JP7290725B2/en active Active
-
2021
- 2021-05-25 PH PH12021551195A patent/PH12021551195A1/en unknown
- 2021-05-26 ZA ZA2021/03596A patent/ZA202103596B/en unknown
-
2022
- 2022-11-07 JP JP2022178427A patent/JP2023011887A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
PH12021551195A1 (en) | 2021-10-25 |
ZA202103596B (en) | 2022-04-28 |
EP3902835A4 (en) | 2022-08-17 |
BR112021009709A2 (en) | 2021-10-19 |
JP2023011887A (en) | 2023-01-24 |
US20230002496A1 (en) | 2023-01-05 |
CN116003597A (en) | 2023-04-25 |
JP2022510171A (en) | 2022-01-26 |
EP3902835A1 (en) | 2021-11-03 |
KR20210129631A (en) | 2021-10-28 |
CA3183309A1 (en) | 2020-06-04 |
CA3120729A1 (en) | 2020-06-04 |
AU2019388584A1 (en) | 2021-06-10 |
KR102655193B1 (en) | 2024-04-04 |
EA202191470A1 (en) | 2021-09-07 |
AU2019388584B2 (en) | 2024-02-15 |
WO2020108423A1 (en) | 2020-06-04 |
CN113348179A (en) | 2021-09-03 |
JP7290725B2 (en) | 2023-06-13 |
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