SG11202104863RA - Antibiotic compounds, methods of manufacturing the same, pharmaceutical compositions containing the same and uses thereof - Google Patents

Antibiotic compounds, methods of manufacturing the same, pharmaceutical compositions containing the same and uses thereof

Info

Publication number
SG11202104863RA
SG11202104863RA SG11202104863RA SG11202104863RA SG11202104863RA SG 11202104863R A SG11202104863R A SG 11202104863RA SG 11202104863R A SG11202104863R A SG 11202104863RA SG 11202104863R A SG11202104863R A SG 11202104863RA SG 11202104863R A SG11202104863R A SG 11202104863RA
Authority
SG
Singapore
Prior art keywords
same
manufacturing
methods
pharmaceutical compositions
compositions containing
Prior art date
Application number
SG11202104863RA
Other languages
English (en)
Inventor
Vincent Gerusz
Vasileios Tatsis
Mihiro Sunose
Juan Bravo
Terry Finn
Danig Pohin
Pierre-Michel Regenass
Original Assignee
Debiopharm Int Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Debiopharm Int Sa filed Critical Debiopharm Int Sa
Publication of SG11202104863RA publication Critical patent/SG11202104863RA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/499Spiro-condensed pyrazines or piperazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/20Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
SG11202104863RA 2018-11-12 2019-11-11 Antibiotic compounds, methods of manufacturing the same, pharmaceutical compositions containing the same and uses thereof SG11202104863RA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18205619 2018-11-12
EP18213016 2018-12-17
PCT/EP2019/080903 WO2020099341A1 (en) 2018-11-12 2019-11-11 Antibiotic compounds, methods of manufacturing the same, pharmaceutical compositions containing the same and uses thereof

Publications (1)

Publication Number Publication Date
SG11202104863RA true SG11202104863RA (en) 2021-06-29

Family

ID=68610175

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202104863RA SG11202104863RA (en) 2018-11-12 2019-11-11 Antibiotic compounds, methods of manufacturing the same, pharmaceutical compositions containing the same and uses thereof

Country Status (15)

Country Link
US (1) US20230035837A1 (es)
EP (1) EP3880675A1 (es)
JP (1) JP2022506957A (es)
KR (1) KR20210093292A (es)
CN (1) CN113272302A (es)
AU (1) AU2019380568A1 (es)
BR (1) BR112021009106A2 (es)
CA (1) CA3119390A1 (es)
CL (2) CL2021001244A1 (es)
IL (1) IL282950A (es)
MX (1) MX2021005535A (es)
PH (1) PH12021551058A1 (es)
SG (1) SG11202104863RA (es)
TN (1) TN2021000092A1 (es)
WO (1) WO2020099341A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022187329A1 (en) * 2021-03-03 2022-09-09 The Board Of Trustees Of The University Of Illinois Fabi inhibitors for gram-negative pathogens
CA3223459A1 (en) 2021-06-23 2022-12-29 Vincent Gerusz Novel compounds and their use

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6921763B2 (en) 1999-09-17 2005-07-26 Abbott Laboratories Pyrazolopyrimidines as therapeutic agents
UY26380A1 (es) 1999-10-08 2001-04-30 Smithkline Beecham Corp Inhibidores de fab i
DK1560584T3 (da) 2001-04-06 2009-05-18 Affinium Pharm Inc Fab I inhibitorer
EP1828167B1 (en) 2004-06-04 2014-08-06 Debiopharm International SA Acrylamide derivatives as antibiotic agents
CN101415701A (zh) * 2005-12-05 2009-04-22 Affinium医药公司 作为fabi抑制剂的杂环丙烯酰胺化合物和抗菌剂
KR20080075027A (ko) 2005-12-05 2008-08-13 아피늄 파마슈티컬스, 인크. Fabi 억제제 및 항박테리아제로서의헤테로시클릴아크릴아미드 화합물
US7601716B2 (en) 2006-05-01 2009-10-13 Cephalon, Inc. Pyridopyrazines and derivatives thereof as ALK and c-Met inhibitors
WO2008009122A1 (en) 2006-07-20 2008-01-24 Affinium Pharmaceuticals, Inc. Acrylamide derivatives as fab i inhibitors
EP2125802A4 (en) 2007-02-16 2014-08-20 Debiopharm Int Sa SALTS, PRODRUGS AND POLYMORPHES OF FAB I INHIBITORS
JO3611B1 (ar) * 2011-08-10 2020-08-27 Janssen Sciences Ireland Uc سايكلو بنتا (سي (بيرول 4,3 ثاني هيدرو 1 hمستبدله [8,1] نافثيريدينونات مضادة للجراثيم
WO2013042035A1 (en) 2011-09-19 2013-03-28 Vitas Pharma Research Private Limited Heterocyclic compounds as inhibitors of fatty acid biosynthesis for bacterial infections
SG11201402409UA (en) 2011-12-02 2014-10-30 Aurigene Discovery Tech Ltd Substituted pyridine derivatives as fabi inhibitors
EA028136B1 (ru) 2012-06-19 2017-10-31 Дибиофарм Интернешнл Са Пролекарственные производные (е)-n-метил-n-((3-метилбензофуран-2-ил)метил)-3-(7-оксо-5,6,7,8-тетрагидро-1,8-нафтиридин-3-ил)акриламида
US9315522B2 (en) 2012-08-10 2016-04-19 Janssen Sciences Ireland Uc Antibacterial compounds
RS60934B1 (sr) 2013-09-30 2020-11-30 Guangzhou Innocare Pharma Tech Co Ltd Supstituisani nikotinimidni inhibitori btk i njihova priprema i upotreba u lečenju karcinoma, inflamatorne i autoimune bolesti

Also Published As

Publication number Publication date
EP3880675A1 (en) 2021-09-22
JP2022506957A (ja) 2022-01-17
CA3119390A1 (en) 2020-05-22
CL2022003703A1 (es) 2023-06-09
IL282950A (en) 2021-06-30
MX2021005535A (es) 2021-09-08
KR20210093292A (ko) 2021-07-27
WO2020099341A1 (en) 2020-05-22
PH12021551058A1 (en) 2021-11-22
BR112021009106A2 (pt) 2021-08-10
US20230035837A1 (en) 2023-02-02
CL2021001244A1 (es) 2021-11-19
TN2021000092A1 (en) 2023-01-05
AU2019380568A1 (en) 2021-06-17
CN113272302A (zh) 2021-08-17

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