SG11202103235PA - COMPOSITIONS AND METHODS REGARDING ENGINEERED AND NON- ENGINEERED γδ-Τ CELLS FOR TREATMENT OF HEMATOLOGICAL TUMORS - Google Patents
COMPOSITIONS AND METHODS REGARDING ENGINEERED AND NON- ENGINEERED γδ-Τ CELLS FOR TREATMENT OF HEMATOLOGICAL TUMORSInfo
- Publication number
- SG11202103235PA SG11202103235PA SG11202103235PA SG11202103235PA SG11202103235PA SG 11202103235P A SG11202103235P A SG 11202103235PA SG 11202103235P A SG11202103235P A SG 11202103235PA SG 11202103235P A SG11202103235P A SG 11202103235PA SG 11202103235P A SG11202103235P A SG 11202103235PA
- Authority
- SG
- Singapore
- Prior art keywords
- engineered
- compositions
- cells
- treatment
- hematological tumors
- Prior art date
Links
- 201000005787 hematologic cancer Diseases 0.000 title 1
- 208000024200 hematopoietic and lymphoid system neoplasm Diseases 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
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- C—CHEMISTRY; METALLURGY
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/622—Single chain antibody (scFv)
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
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- C07K2319/00—Fusion polypeptide
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
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- Wood Science & Technology (AREA)
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- Hematology (AREA)
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862739822P | 2018-10-01 | 2018-10-01 | |
PCT/US2019/054132 WO2020072536A1 (en) | 2018-10-01 | 2019-10-01 | COMPOSITIONS AND METHODS REGARDING ENGINEERED AND NON- ENGINEERED γδ-Τ CELLS FOR TREATMENT OF HEMATOLOGICAL TUMORS |
Publications (1)
Publication Number | Publication Date |
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SG11202103235PA true SG11202103235PA (en) | 2021-04-29 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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SG11202103235PA SG11202103235PA (en) | 2018-10-01 | 2019-10-01 | COMPOSITIONS AND METHODS REGARDING ENGINEERED AND NON- ENGINEERED γδ-Τ CELLS FOR TREATMENT OF HEMATOLOGICAL TUMORS |
Country Status (13)
Country | Link |
---|---|
US (1) | US20210388100A1 (en) |
EP (1) | EP3860645A1 (en) |
JP (1) | JP2022501074A (en) |
KR (1) | KR20210070330A (en) |
CN (1) | CN113056283A (en) |
AU (1) | AU2019354391A1 (en) |
BR (1) | BR112021006182A2 (en) |
CA (1) | CA3115139A1 (en) |
EA (1) | EA202190926A1 (en) |
IL (1) | IL281922A (en) |
MX (1) | MX2021003745A (en) |
SG (1) | SG11202103235PA (en) |
WO (1) | WO2020072536A1 (en) |
Families Citing this family (2)
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CN113402612A (en) | 2020-03-17 | 2021-09-17 | 西比曼生物科技(香港)有限公司 | Combined chimeric antigen receptor targeting CD19 and CD20 and application thereof |
CN113667640B (en) * | 2021-08-27 | 2022-09-02 | 广州百暨基因科技有限公司 | Method for preparing CAR-gamma delta T cells |
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PT1809321E (en) | 2004-10-08 | 2012-05-17 | Us Gov Health & Human Serv | Adoptive immunotherapy with enhanced t lymphocyte survival |
CA2695199C (en) * | 2007-07-31 | 2016-07-19 | Regeneron Pharmaceuticals, Inc. | Human antibodies to human cd20 and method of using thereof |
WO2010042490A1 (en) | 2008-10-06 | 2010-04-15 | Boston Medical Center Corporation | A single lentiviral vector system for induced pluripotent (ips) stem cells derivation |
ES2700966T3 (en) | 2010-12-09 | 2019-02-20 | Univ Pennsylvania | Use of modified T lymphocytes with chimeric antigen receptors to treat cancer |
ES2643387T3 (en) | 2011-05-19 | 2017-11-22 | Instituto De Medicina Molecular | Lymphocyte cell line comprising gamma-delta cells, composition and method of production thereof |
CN104087607B (en) * | 2013-04-01 | 2017-06-20 | 科济生物医药(上海)有限公司 | The nucleic acid of encoding chimeric antigen receptor protein and the T lymphocytes of expression Chimeric antigen receptor albumen |
KR20160068960A (en) | 2013-10-25 | 2016-06-15 | 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 | Polyclonal gamma delta t cells for immunotherapy |
CN107075480A (en) | 2014-07-09 | 2017-08-18 | Tc生物制药有限公司 | Gamma delta T cells and application thereof |
GB201506423D0 (en) | 2015-04-15 | 2015-05-27 | Tc Biopharm Ltd | Gamma delta T cells and uses thereof |
SG11201700476VA (en) * | 2014-07-21 | 2017-02-27 | Novartis Ag | Treatment of cancer using humanized anti-bcma chimeric antigen receptor |
WO2016034666A1 (en) * | 2014-09-04 | 2016-03-10 | Cellectis | Trophoblast glycoprotein (5t4, tpbg) specific chimeric antigen receptors for cancer immunotherapy |
AU2015350103A1 (en) | 2014-11-17 | 2017-06-29 | Adicet Bio, Inc. | Engineered gamma delta T-cells |
GB201507368D0 (en) * | 2015-04-30 | 2015-06-17 | Ucl Business Plc | Cell |
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-
2019
- 2019-10-01 WO PCT/US2019/054132 patent/WO2020072536A1/en unknown
- 2019-10-01 EP EP19795699.8A patent/EP3860645A1/en active Pending
- 2019-10-01 SG SG11202103235PA patent/SG11202103235PA/en unknown
- 2019-10-01 CA CA3115139A patent/CA3115139A1/en active Pending
- 2019-10-01 KR KR1020217012805A patent/KR20210070330A/en unknown
- 2019-10-01 EA EA202190926A patent/EA202190926A1/en unknown
- 2019-10-01 JP JP2021542089A patent/JP2022501074A/en active Pending
- 2019-10-01 AU AU2019354391A patent/AU2019354391A1/en active Pending
- 2019-10-01 BR BR112021006182-7A patent/BR112021006182A2/en unknown
- 2019-10-01 MX MX2021003745A patent/MX2021003745A/en unknown
- 2019-10-01 US US17/281,574 patent/US20210388100A1/en active Pending
- 2019-10-01 CN CN201980070384.5A patent/CN113056283A/en active Pending
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2021
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CA3115139A1 (en) | 2020-04-09 |
WO2020072536A1 (en) | 2020-04-09 |
WO2020072536A9 (en) | 2020-06-25 |
CN113056283A (en) | 2021-06-29 |
US20210388100A1 (en) | 2021-12-16 |
EP3860645A1 (en) | 2021-08-11 |
AU2019354391A1 (en) | 2021-05-06 |
BR112021006182A2 (en) | 2021-06-29 |
IL281922A (en) | 2021-05-31 |
KR20210070330A (en) | 2021-06-14 |
EA202190926A1 (en) | 2021-06-25 |
JP2022501074A (en) | 2022-01-06 |
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