SG11202103235PA - COMPOSITIONS AND METHODS REGARDING ENGINEERED AND NON- ENGINEERED γδ-Τ CELLS FOR TREATMENT OF HEMATOLOGICAL TUMORS - Google Patents

COMPOSITIONS AND METHODS REGARDING ENGINEERED AND NON- ENGINEERED γδ-Τ CELLS FOR TREATMENT OF HEMATOLOGICAL TUMORS

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Publication number
SG11202103235PA
SG11202103235PA SG11202103235PA SG11202103235PA SG11202103235PA SG 11202103235P A SG11202103235P A SG 11202103235PA SG 11202103235P A SG11202103235P A SG 11202103235PA SG 11202103235P A SG11202103235P A SG 11202103235PA SG 11202103235P A SG11202103235P A SG 11202103235PA
Authority
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Singapore
Prior art keywords
engineered
compositions
cells
treatment
hematological tumors
Prior art date
Application number
SG11202103235PA
Inventor
Daulet Satpayev
Marissa Herrman
Jason Romero
Yifeng Jing
Zili An
Aya Jakobovits
Original Assignee
Adicet Bio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adicet Bio Inc filed Critical Adicet Bio Inc
Publication of SG11202103235PA publication Critical patent/SG11202103235PA/en

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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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    • C07K2317/00—Immunoglobulins specific features
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    • C07K2319/00—Fusion polypeptide
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SG11202103235PA 2018-10-01 2019-10-01 COMPOSITIONS AND METHODS REGARDING ENGINEERED AND NON- ENGINEERED γδ-Τ CELLS FOR TREATMENT OF HEMATOLOGICAL TUMORS SG11202103235PA (en)

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US201862739822P 2018-10-01 2018-10-01
PCT/US2019/054132 WO2020072536A1 (en) 2018-10-01 2019-10-01 COMPOSITIONS AND METHODS REGARDING ENGINEERED AND NON- ENGINEERED γδ-Τ CELLS FOR TREATMENT OF HEMATOLOGICAL TUMORS

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US (1) US20210388100A1 (en)
EP (1) EP3860645A1 (en)
JP (1) JP2022501074A (en)
KR (1) KR20210070330A (en)
CN (1) CN113056283A (en)
AU (1) AU2019354391A1 (en)
BR (1) BR112021006182A2 (en)
CA (1) CA3115139A1 (en)
EA (1) EA202190926A1 (en)
IL (1) IL281922A (en)
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CN113402612A (en) 2020-03-17 2021-09-17 西比曼生物科技（香港）有限公司 Combined chimeric antigen receptor targeting CD19 and CD20 and application thereof
CN113667640B (en) * 2021-08-27 2022-09-02 广州百暨基因科技有限公司 Method for preparing CAR-gamma delta T cells

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CA2695199C (en) * 2007-07-31 2016-07-19 Regeneron Pharmaceuticals, Inc. Human antibodies to human cd20 and method of using thereof
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ES2700966T3 (en) 2010-12-09 2019-02-20 Univ Pennsylvania Use of modified T lymphocytes with chimeric antigen receptors to treat cancer
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CN104087607B (en) * 2013-04-01 2017-06-20 科济生物医药（上海）有限公司 The nucleic acid of encoding chimeric antigen receptor protein and the T lymphocytes of expression Chimeric antigen receptor albumen
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