SG11202102110PA - Novel hydrochloride salt forms of a sulfonamide structured kinase inhibitor - Google Patents

Novel hydrochloride salt forms of a sulfonamide structured kinase inhibitor

Info

Publication number
SG11202102110PA
SG11202102110PA SG11202102110PA SG11202102110PA SG11202102110PA SG 11202102110P A SG11202102110P A SG 11202102110PA SG 11202102110P A SG11202102110P A SG 11202102110PA SG 11202102110P A SG11202102110P A SG 11202102110PA SG 11202102110P A SG11202102110P A SG 11202102110PA
Authority
SG
Singapore
Prior art keywords
sulfonamide
structured
kinase inhibitor
hydrochloride salt
salt forms
Prior art date
Application number
SG11202102110PA
Other languages
English (en)
Inventor
David Jonaitis
Oskari Karjalainen
Original Assignee
Orion Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Corp filed Critical Orion Corp
Publication of SG11202102110PA publication Critical patent/SG11202102110PA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/04Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by halogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41841,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SG11202102110PA 2018-09-06 2019-09-05 Novel hydrochloride salt forms of a sulfonamide structured kinase inhibitor SG11202102110PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI20185743 2018-09-06
PCT/FI2019/050629 WO2020049217A1 (fr) 2018-09-06 2019-09-05 Nouvelles formes salines de chlorhydrate d'un inhibiteur de kinase à structure sulfamide

Publications (1)

Publication Number Publication Date
SG11202102110PA true SG11202102110PA (en) 2021-04-29

Family

ID=67982092

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202102110PA SG11202102110PA (en) 2018-09-06 2019-09-05 Novel hydrochloride salt forms of a sulfonamide structured kinase inhibitor

Country Status (12)

Country Link
US (1) US11866420B2 (fr)
EP (1) EP3846906A1 (fr)
JP (1) JP7528060B2 (fr)
KR (1) KR20210057759A (fr)
CN (1) CN112805065B (fr)
AU (1) AU2019334693A1 (fr)
CA (1) CA3111040A1 (fr)
EA (1) EA202190696A1 (fr)
MA (1) MA53546A (fr)
MX (1) MX2021002524A (fr)
SG (1) SG11202102110PA (fr)
WO (1) WO2020049217A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023516358A (ja) * 2020-03-05 2023-04-19 オーリジーン ディスカバリー テクノロジーズ リミテッド キナーゼ阻害剤の医薬組成物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA111382C2 (uk) 2011-10-10 2016-04-25 Оріон Корпорейшн Інгібітори протеїнкінази
US10870637B2 (en) * 2017-03-23 2020-12-22 Orion Corporation Process for the preparation of a sulfonamide structured kinase inhibitor
WO2020135878A1 (fr) * 2018-12-29 2020-07-02 南京明德新药研发有限公司 Dérivé d'imidazopyridine utilisé en tant qu'inhibiteur double de fgfr et vegfr
AU2020292664B2 (en) * 2019-06-14 2023-04-13 Cgenetech (Suzhou, China) Co., Ltd. Fused ring compound as FGFR and VEGFR dual inhibitor

Also Published As

Publication number Publication date
CN112805065B (zh) 2024-07-05
CN112805065A (zh) 2021-05-14
MA53546A (fr) 2021-12-15
CA3111040A1 (fr) 2020-03-12
JP7528060B2 (ja) 2024-08-05
MX2021002524A (es) 2021-04-28
US11866420B2 (en) 2024-01-09
WO2020049217A1 (fr) 2020-03-12
JP2022501328A (ja) 2022-01-06
KR20210057759A (ko) 2021-05-21
EA202190696A1 (ru) 2021-06-16
EP3846906A1 (fr) 2021-07-14
US20210332028A1 (en) 2021-10-28
AU2019334693A1 (en) 2021-05-13

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