SG11202100374XA - Therapeutic dendrimer - Google Patents
Therapeutic dendrimerInfo
- Publication number
- SG11202100374XA SG11202100374XA SG11202100374XA SG11202100374XA SG11202100374XA SG 11202100374X A SG11202100374X A SG 11202100374XA SG 11202100374X A SG11202100374X A SG 11202100374XA SG 11202100374X A SG11202100374X A SG 11202100374XA SG 11202100374X A SG11202100374X A SG 11202100374XA
- Authority
- SG
- Singapore
- Prior art keywords
- dendrimer
- therapeutic
- therapeutic dendrimer
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G83/00—Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
- C08G83/002—Dendritic macromolecules
- C08G83/003—Dendrimers
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G83/00—Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
- C08G83/002—Dendritic macromolecules
- C08G83/003—Dendrimers
- C08G83/004—After treatment of dendrimers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/645—Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
- C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
- C08G69/08—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
- C08G69/10—Alpha-amino-carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2018902611A AU2018902611A0 (en) | 2018-07-19 | Therapeutic dendrimer | |
PCT/AU2019/050759 WO2020014750A1 (en) | 2018-07-19 | 2019-07-19 | Therapeutic dendrimer |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202100374XA true SG11202100374XA (en) | 2021-02-25 |
Family
ID=69163458
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202100374XA SG11202100374XA (en) | 2018-07-19 | 2019-07-19 | Therapeutic dendrimer |
Country Status (11)
Country | Link |
---|---|
US (2) | US11118016B2 (en) |
EP (1) | EP3823961A4 (en) |
JP (1) | JP2021529818A (en) |
KR (1) | KR20210034011A (en) |
CN (1) | CN112424178A (en) |
AU (1) | AU2019306745A1 (en) |
BR (1) | BR112021000658A2 (en) |
CA (1) | CA3106568A1 (en) |
MX (1) | MX2021000677A (en) |
SG (1) | SG11202100374XA (en) |
WO (1) | WO2020014750A1 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3823961A4 (en) | 2018-07-19 | 2022-06-08 | Starpharma Pty Limited | Therapeutic dendrimer |
WO2022040761A1 (en) * | 2020-08-31 | 2022-03-03 | Starpharma Pty Ltd | Dendrimer-drug conjugate |
KR20230079035A (en) * | 2020-09-14 | 2023-06-05 | 주하이 베이하이 바이오테크 컴퍼니 리미티드 | Formulations of Cabazitaxel |
Family Cites Families (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5840900A (en) | 1993-10-20 | 1998-11-24 | Enzon, Inc. | High molecular weight polymer-based prodrugs |
US6230913B1 (en) | 1998-01-30 | 2001-05-15 | The Popstraw Company, Llc | Straw in a bottle |
CA2396702C (en) | 2000-01-04 | 2010-03-23 | Access Pharmaceuticals, Inc. | N,o-amidomalonate platinum complexes |
US6471968B1 (en) * | 2000-05-12 | 2002-10-29 | Regents Of The University Of Michigan | Multifunctional nanodevice platform |
DE10041559A1 (en) | 2000-08-24 | 2002-03-07 | Basf Ag | Use of copolymer of amino acid and co-condensable compound in cosmetic and dermatological products, has better water solubility than polyamino acids |
AUPR412801A0 (en) * | 2001-03-30 | 2001-05-03 | Starpharma Limited | Agent for the prevention and treatment of sexually transmitted disease s - I |
US7261875B2 (en) * | 2001-12-21 | 2007-08-28 | Board Of Regents, The University Of Texas System | Dendritic poly (amino acid) carriers and methods of use |
US20100136614A1 (en) | 2005-10-18 | 2010-06-03 | Dan Luo | Dendrimer-like modular delivery vector |
PT1940916T (en) | 2005-10-25 | 2017-03-20 | Starpharma Pty Ltd | Macromolecular compounds having controlled stoichiometry |
US20110014151A1 (en) * | 2006-01-11 | 2011-01-20 | Biotech Igg Ab | Macromolecule conjugate |
US8337823B2 (en) | 2006-01-20 | 2012-12-25 | Starpharma Pty Limited | Modified macromolecule |
DK2052011T3 (en) | 2006-08-11 | 2020-12-07 | Starpharma Pty Ltd | TARGETED POLYLYSIN-DENDRIMER-THERAPEUTIC SUBSTANCE |
US9127130B2 (en) | 2006-08-11 | 2015-09-08 | Starpharma Pty Ltd. | Polylysine dendrimer contrast agent |
DK2306986T3 (en) | 2008-06-26 | 2018-06-18 | Prolynx Llc | PRODRUGS AND PHARMACEUTICAL Macromolecule Conjugates with Controlled Drug Release Rates |
CN103932972A (en) * | 2009-03-30 | 2014-07-23 | 天蓝制药公司 | Polymer-agent Conjugates, Particles, Compositions, And Related Methods Of Use |
WO2011072290A2 (en) | 2009-12-11 | 2011-06-16 | The Regents Of The University Of Michigan | Targeted dendrimer-drug conjugates |
US8703907B2 (en) | 2010-05-05 | 2014-04-22 | Prolynx Llc | Controlled drug release from dendrimers |
JP5964815B2 (en) | 2010-05-05 | 2016-08-03 | プロリンクス リミテッド ライアビリティ カンパニー | Controlled release drug from solid carrier |
DK2566335T3 (en) | 2010-05-05 | 2016-10-03 | Prolynx Llc | Controlled release of active ingredients from macromolecular CONJUGATES |
FR2967581B1 (en) * | 2010-11-19 | 2012-12-28 | Sanofi Aventis | POLYMERIC CONJUGATES OF ACTIVE INGREDIENTS, PROCESS FOR THEIR PREPARATION AND POLYMERIC INTERMEDIATES |
CN102120036B (en) | 2011-02-22 | 2013-07-24 | 中国科学院长春应用化学研究所 | Nano micelle of biodegradable macromolecular-bonding Pt(IV) anti-cancer medicament and preparation method thereof |
US20180326081A1 (en) | 2011-06-06 | 2018-11-15 | Starpharma Pty Ltd | Macromolecules |
US9744246B2 (en) * | 2011-06-06 | 2017-08-29 | Starpharma Pty Ltd | Macromolecules |
US20140296257A1 (en) * | 2011-08-12 | 2014-10-02 | Ascendis Pharma A/S | High-Loading Water-Soluable Carrier-Linked Prodrugs |
WO2014036323A1 (en) | 2012-08-29 | 2014-03-06 | Mannkind Corporation | Method and composition for treating hyperglycemia |
US20160220689A1 (en) * | 2013-09-10 | 2016-08-04 | Starpharma Pty Ltd. | Macromolecules of dendrimer-platinum conjugates |
US10730999B2 (en) * | 2014-06-06 | 2020-08-04 | Starpharma Pty Ltd | Dendrimer-drug conjugates |
WO2018053316A1 (en) * | 2016-09-15 | 2018-03-22 | The Regents Of The University Of California | Improved hybrid telodendrimers |
EP3823961A4 (en) | 2018-07-19 | 2022-06-08 | Starpharma Pty Limited | Therapeutic dendrimer |
-
2019
- 2019-07-19 EP EP19837424.1A patent/EP3823961A4/en active Pending
- 2019-07-19 MX MX2021000677A patent/MX2021000677A/en unknown
- 2019-07-19 AU AU2019306745A patent/AU2019306745A1/en active Pending
- 2019-07-19 BR BR112021000658-3A patent/BR112021000658A2/en unknown
- 2019-07-19 SG SG11202100374XA patent/SG11202100374XA/en unknown
- 2019-07-19 CN CN201980046801.2A patent/CN112424178A/en active Pending
- 2019-07-19 JP JP2021501311A patent/JP2021529818A/en active Pending
- 2019-07-19 CA CA3106568A patent/CA3106568A1/en active Pending
- 2019-07-19 KR KR1020217003648A patent/KR20210034011A/en not_active Application Discontinuation
- 2019-07-19 WO PCT/AU2019/050759 patent/WO2020014750A1/en active Application Filing
-
2020
- 2020-08-26 US US17/003,699 patent/US11118016B2/en active Active
-
2021
- 2021-08-25 US US17/411,582 patent/US11970583B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
KR20210034011A (en) | 2021-03-29 |
AU2019306745A1 (en) | 2021-02-18 |
US11118016B2 (en) | 2021-09-14 |
MX2021000677A (en) | 2021-03-25 |
US20200392295A1 (en) | 2020-12-17 |
CA3106568A1 (en) | 2020-01-23 |
CN112424178A (en) | 2021-02-26 |
JP2021529818A (en) | 2021-11-04 |
EP3823961A1 (en) | 2021-05-26 |
EP3823961A4 (en) | 2022-06-08 |
WO2020014750A1 (en) | 2020-01-23 |
BR112021000658A2 (en) | 2021-04-13 |
US20210380765A1 (en) | 2021-12-09 |
US11970583B2 (en) | 2024-04-30 |
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