SG11202012765PA - Novel compounds - Google Patents
Novel compoundsInfo
- Publication number
- SG11202012765PA SG11202012765PA SG11202012765PA SG11202012765PA SG11202012765PA SG 11202012765P A SG11202012765P A SG 11202012765PA SG 11202012765P A SG11202012765P A SG 11202012765PA SG 11202012765P A SG11202012765P A SG 11202012765PA SG 11202012765P A SG11202012765P A SG 11202012765PA
- Authority
- SG
- Singapore
- Prior art keywords
- novel compounds
- novel
- compounds
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1810290.5A GB201810290D0 (en) | 2018-06-22 | 2018-06-22 | Novel Compounds |
| GBGB1906708.1A GB201906708D0 (en) | 2019-05-13 | 2019-05-13 | Novel compounds |
| PCT/GB2019/051761 WO2019243841A1 (en) | 2018-06-22 | 2019-06-21 | Novel compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202012765PA true SG11202012765PA (en) | 2021-01-28 |
Family
ID=67139769
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202012765PA SG11202012765PA (en) | 2018-06-22 | 2019-06-21 | Novel compounds |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20210276952A1 (en) |
| EP (1) | EP3810131A1 (en) |
| CN (1) | CN113286586A (en) |
| AU (1) | AU2019289228A1 (en) |
| BR (1) | BR112020026314A2 (en) |
| CA (1) | CA3103920A1 (en) |
| IL (1) | IL279526A (en) |
| MX (1) | MX2020013853A (en) |
| SG (1) | SG11202012765PA (en) |
| WO (1) | WO2019243841A1 (en) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20210089656A (en) | 2018-10-05 | 2021-07-16 | 버텍스 파마슈티칼스 인코포레이티드 | Alpha-1 antitrypsin modulators |
| US11884672B2 (en) | 2019-05-14 | 2024-01-30 | Vertex Pharmaceuticals Incorporated | Modulators of alpha-1 antitrypsin |
| GB201918416D0 (en) | 2019-12-13 | 2020-01-29 | Z Factor Ltd | Compounds and their use for the treatment of Alpha1-Antitrypsin deficiency |
| GB201918404D0 (en) | 2019-12-13 | 2020-01-29 | Z Factor Ltd | Compounds and their use for the treatment of aplha1-antitrypsin deficiency |
| GB201918413D0 (en) | 2019-12-13 | 2020-01-29 | Z Factor Ltd | Compounds and their use for the treatment of alpha1-antitrypsin deficiency |
| GB201918410D0 (en) | 2019-12-13 | 2020-01-29 | Z Factor Ltd | Compounds and their use for the treatment of alpha1-antitrypsin deficiency |
| GB201918414D0 (en) | 2019-12-13 | 2020-01-29 | Z Factor Ltd | Compounds and their use for the treatment of Alpha1-Antitrypsin deficiency |
| KR20220163429A (en) * | 2020-04-03 | 2022-12-09 | 버텍스 파마슈티칼스 인코포레이티드 | Pyrrolo[2,3-F]indazole derivatives and 2,4,5,10-tetraazatricyclo[7.3.0.03 as alpha-1-antitrypsin modulators for the treatment of alpha-1-antitrypsin deficiency (AATD) ,7] dodeca-1,3(7),5,8,11-pentaene derivatives |
| CN115715292A (en) * | 2020-04-03 | 2023-02-24 | 弗特克斯药品有限公司 | 1H-pyrazolo [4,3-g ] isoquinoline and 1H-pyrazolo [4,3-g ] quinoline derivatives as alpha-1-antitrypsin modulators for the treatment of alpha-1-antitrypsin deficiency (AATD) |
| MX2022011829A (en) * | 2020-04-03 | 2022-12-15 | Vertex Pharma | Indole derivatives as alpha-1 -antitrypsin modulators for treating alpha-1 -antitrypsin deficiency (aatd). |
| EP4126819A1 (en) * | 2020-04-03 | 2023-02-08 | Vertex Pharmaceuticals Incorporated | 7- or 8-hydroxy-isoquinoline and 7- or 8-hydroxy-quinoline derivatives as alpha-1 -antitrypsin modulators for treating alpha-1 -antitrypsin deficiency (aatd) |
| EP4126881A1 (en) * | 2020-04-03 | 2023-02-08 | Vertex Pharmaceuticals Incorporated | Pyrano[4,3-b]l ndole derivatives as alpha-1 -antitrypsin modulators for treating alpha-1 -antitrypsin deficiency (aatd) |
| GB202009074D0 (en) | 2020-06-15 | 2020-07-29 | Z Factor Ltd | Compound |
| GB202108523D0 (en) | 2021-06-15 | 2021-07-28 | Z Factor Ltd | Compositions and their use for the treatment of alpha1-antitrypsin deficiency |
| CN113801053B (en) * | 2021-11-01 | 2023-09-08 | 上海皓鸿生物医药科技有限公司 | Method for preparing 7-fluoro-2-oxoindoline-4-carboxylic acid |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3818830A1 (en) * | 1988-06-03 | 1989-12-14 | Boehringer Mannheim Gmbh | BICYCLIC CARBOXAMIDS, METHOD FOR THE PRODUCTION THEREOF, AND THE MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS |
| US5569450A (en) | 1993-03-17 | 1996-10-29 | Minnesota Mining And Manufacturing Company | Aerosol formulation containing an ester-, amide-, or mercaptoester-derived dispersing aid |
| US6126919A (en) | 1997-02-07 | 2000-10-03 | 3M Innovative Properties Company | Biocompatible compounds for pharmaceutical drug delivery systems |
| US7232818B2 (en) * | 2004-04-15 | 2007-06-19 | Proteolix, Inc. | Compounds for enzyme inhibition |
| US9801637B2 (en) | 2006-03-13 | 2017-10-31 | Pneumrx, Inc. | Genetically-associated chronic obstructive pulmonary disease treatment |
| WO2008143633A2 (en) | 2007-01-10 | 2008-11-27 | University Of Florida | Compounds and methods for treatment of alpha-1 antitrypsin deficiency |
| KR101402702B1 (en) | 2011-09-15 | 2014-06-05 | (주)알테오젠 | New alpha-1 antitrypsin variant, method for producing the same and use thereof |
| RU2722019C2 (en) * | 2015-12-03 | 2020-05-26 | Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед | Cyclic purine dinucleotides as modulators of sting |
| CN113801053B (en) | 2021-11-01 | 2023-09-08 | 上海皓鸿生物医药科技有限公司 | Method for preparing 7-fluoro-2-oxoindoline-4-carboxylic acid |
-
2019
- 2019-06-21 CN CN201980054648.8A patent/CN113286586A/en active Pending
- 2019-06-21 SG SG11202012765PA patent/SG11202012765PA/en unknown
- 2019-06-21 BR BR112020026314-1A patent/BR112020026314A2/en unknown
- 2019-06-21 MX MX2020013853A patent/MX2020013853A/en unknown
- 2019-06-21 EP EP19735375.8A patent/EP3810131A1/en active Pending
- 2019-06-21 AU AU2019289228A patent/AU2019289228A1/en active Pending
- 2019-06-21 US US17/254,854 patent/US20210276952A1/en not_active Abandoned
- 2019-06-21 CA CA3103920A patent/CA3103920A1/en active Pending
- 2019-06-21 WO PCT/GB2019/051761 patent/WO2019243841A1/en unknown
-
2020
- 2020-12-17 IL IL279526A patent/IL279526A/en unknown
-
2022
- 2022-06-23 US US17/848,156 patent/US11919856B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US11919856B2 (en) | 2024-03-05 |
| IL279526A (en) | 2021-01-31 |
| MX2020013853A (en) | 2021-05-27 |
| BR112020026314A2 (en) | 2021-03-30 |
| CN113286586A (en) | 2021-08-20 |
| US20210276952A1 (en) | 2021-09-09 |
| AU2019289228A1 (en) | 2021-01-21 |
| EP3810131A1 (en) | 2021-04-28 |
| CA3103920A1 (en) | 2019-12-26 |
| US20220340525A1 (en) | 2022-10-27 |
| WO2019243841A1 (en) | 2019-12-26 |
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