SG11202010208YA - The kit for screening colorectal cancer and advanced adenoma and its application - Google Patents

The kit for screening colorectal cancer and advanced adenoma and its application

Info

Publication number
SG11202010208YA
SG11202010208YA SG11202010208YA SG11202010208YA SG11202010208YA SG 11202010208Y A SG11202010208Y A SG 11202010208YA SG 11202010208Y A SG11202010208Y A SG 11202010208YA SG 11202010208Y A SG11202010208Y A SG 11202010208YA SG 11202010208Y A SG11202010208Y A SG 11202010208YA
Authority
SG
Singapore
Prior art keywords
kit
application
colorectal cancer
advanced adenoma
screening colorectal
Prior art date
Application number
SG11202010208YA
Inventor
Cunyao Li
Hui Li
Yiyou Chen
Weixian Zheng
Jiao Yang
Gang Liu
Ning Lv
Original Assignee
Hangzhou New Horizon Health Tech Co Ltd
Yiyou Chen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN201810502359.7A external-priority patent/CN108660209B/en
Priority claimed from CN201810502387.9A external-priority patent/CN108676878B/en
Application filed by Hangzhou New Horizon Health Tech Co Ltd, Yiyou Chen filed Critical Hangzhou New Horizon Health Tech Co Ltd
Publication of SG11202010208YA publication Critical patent/SG11202010208YA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721Haemoglobin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2561/00Nucleic acid detection characterised by assay method
    • C12Q2561/113Real time assay
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/154Methylation markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/16Primer sets for multiplex assays
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/166Oligonucleotides used as internal standards, controls or normalisation probes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hospice & Palliative Care (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG11202010208YA 2018-05-23 2019-05-23 The kit for screening colorectal cancer and advanced adenoma and its application SG11202010208YA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201810502359.7A CN108660209B (en) 2018-05-23 2018-05-23 Product for early detection of colorectal cancer prepared based on BMP3 gene methylation
CN201810502387.9A CN108676878B (en) 2018-05-23 2018-05-23 Application of product for detecting NDRG4 gene methylation site in preparation of product for early detection of colorectal cancer
PCT/US2019/033831 WO2019226942A1 (en) 2018-05-23 2019-05-23 The kit for screening colorectal cancer and advanced adenoma and its application

Publications (1)

Publication Number Publication Date
SG11202010208YA true SG11202010208YA (en) 2020-11-27

Family

ID=68617194

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202010208YA SG11202010208YA (en) 2018-05-23 2019-05-23 The kit for screening colorectal cancer and advanced adenoma and its application

Country Status (10)

Country Link
US (1) US20210207221A1 (en)
EP (1) EP3797112A4 (en)
JP (1) JP2021526370A (en)
KR (1) KR20210035094A (en)
CN (1) CN112752763A (en)
AU (1) AU2019275073A1 (en)
BR (1) BR112020023274A2 (en)
CA (1) CA3098028A1 (en)
SG (1) SG11202010208YA (en)
WO (1) WO2019226942A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113699237A (en) * 2020-07-29 2021-11-26 上海吉凯医学检验所有限公司 Kit for detecting DNA methylation markers of early colorectal cancer and adenoma

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5541308A (en) * 1986-11-24 1996-07-30 Gen-Probe Incorporated Nucleic acid probes for detection and/or quantitation of non-viral organisms
JP2004516821A (en) * 2000-09-01 2004-06-10 エピゲノミクス アーゲー Method for quantifying the degree of methylation of specific cytosine in sequence context 5-CpG-3 on genomic DNA
DE10112515B4 (en) * 2001-03-09 2004-02-12 Epigenomics Ag Method for the detection of cytosine methylation patterns with high sensitivity
AU2012253345B2 (en) * 2011-05-12 2016-10-20 Exact Sciences Corporation Isolation of nucleic acids
WO2013142545A1 (en) * 2012-03-20 2013-09-26 Exact Sciences Corporation Marker panel for detecting cancer
US11078539B2 (en) * 2014-03-31 2021-08-03 Mayo Foundation For Medical Education And Research Detecting colorectal neoplasm
EP3230476B1 (en) * 2014-12-12 2020-02-05 Exact Sciences Development Company, LLC Zdhhc1 for normalizing methylation detection assays
CN107003314B (en) * 2014-12-12 2021-10-15 精密科学公司 Compositions and methods for performing methylation detection assays
CN104975110A (en) * 2015-06-02 2015-10-14 浙江诺辉生物技术有限公司 Primer and probe for detecting methylation levels of BMP3 and NDRG4 in biological sample
EP3368686A1 (en) * 2015-10-30 2018-09-05 Exact Sciences Development Company, LLC Multiplex amplification detection assay and isolation and detection of dna from plasma
WO2018087129A1 (en) * 2016-11-08 2018-05-17 Region Nordjylland, Aalborg University Hospital Colorectal cancer methylation markers
CN106399570A (en) * 2016-11-30 2017-02-15 杭州诺辉健康科技有限公司 Kit for early stage colorectal cancer auxiliary diagnosis and use method and detection system thereof

Also Published As

Publication number Publication date
EP3797112A4 (en) 2022-03-23
BR112020023274A2 (en) 2021-02-23
US20210207221A1 (en) 2021-07-08
AU2019275073A1 (en) 2020-11-26
EP3797112A1 (en) 2021-03-31
KR20210035094A (en) 2021-03-31
AU2019275073A8 (en) 2020-12-10
CA3098028A1 (en) 2019-11-28
WO2019226942A1 (en) 2019-11-28
JP2021526370A (en) 2021-10-07
CN112752763A (en) 2021-05-04

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