SG11202010178XA - Buffered formulations of bevacizumab for use of treating diseases - Google Patents

Buffered formulations of bevacizumab for use of treating diseases

Info

Publication number
SG11202010178XA
SG11202010178XA SG11202010178XA SG11202010178XA SG11202010178XA SG 11202010178X A SG11202010178X A SG 11202010178XA SG 11202010178X A SG11202010178X A SG 11202010178XA SG 11202010178X A SG11202010178X A SG 11202010178XA SG 11202010178X A SG11202010178X A SG 11202010178XA
Authority
SG
Singapore
Prior art keywords
bevacizumab
treating diseases
buffered formulations
buffered
formulations
Prior art date
Application number
SG11202010178XA
Inventor
Chris Yonan
Wiphusanee Dendamrongvit
Martha Healy-Fried
Original Assignee
Outlook Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Outlook Therapeutics Inc filed Critical Outlook Therapeutics Inc
Publication of SG11202010178XA publication Critical patent/SG11202010178XA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591Stabilisation, fragmentation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
SG11202010178XA 2018-04-17 2019-04-17 Buffered formulations of bevacizumab for use of treating diseases SG11202010178XA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862658772P 2018-04-17 2018-04-17
US201862776686P 2018-12-07 2018-12-07
PCT/US2019/027790 WO2019204380A1 (en) 2018-04-17 2019-04-17 Buffered formulations of bevacizumab for use of treating diseases

Publications (1)

Publication Number Publication Date
SG11202010178XA true SG11202010178XA (en) 2020-11-27

Family

ID=66429576

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202010178XA SG11202010178XA (en) 2018-04-17 2019-04-17 Buffered formulations of bevacizumab for use of treating diseases

Country Status (12)

Country Link
US (1) US20210230261A1 (en)
EP (1) EP3781199A1 (en)
JP (1) JP2021522180A (en)
KR (1) KR20210011923A (en)
CN (1) CN112543645A (en)
AU (1) AU2019256289A1 (en)
BR (1) BR112020021255A2 (en)
CA (1) CA3097123A1 (en)
IL (1) IL278041A (en)
MX (1) MX2020010968A (en)
SG (1) SG11202010178XA (en)
WO (1) WO2019204380A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9840553B2 (en) 2014-06-28 2017-12-12 Kodiak Sciences Inc. Dual PDGF/VEGF antagonists
KR20180104635A (en) 2015-12-30 2018-09-21 코디악 사이언시스 인코포레이티드 Antibodies and conjugates thereof
MX2021009851A (en) 2019-02-18 2021-09-10 Lilly Co Eli Therapeutic antibody formulation.
CN114786731A (en) 2019-10-10 2022-07-22 科达制药股份有限公司 Methods of treating ocular disorders
CN115066262A (en) * 2020-03-04 2022-09-16 上海复宏汉霖生物技术股份有限公司 Pharmaceutical formulation comprising bevacizumab
CN113546172A (en) * 2020-04-24 2021-10-26 山东大学齐鲁医院 Application of VEGF inhibitor in preparation of medicine for treating hypoxia-related diseases
WO2022006091A1 (en) * 2020-06-29 2022-01-06 Anovent Pharmaceutical (U.S.), Llc Biopharmaceutical formulation of anti-pd-1, anti-pd-l1, and anti-vegfr therapeutic monoclonal antibodies and method for treating nsclc by inhalation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11078262B2 (en) * 2007-04-30 2021-08-03 Allergan, Inc. High viscosity macromolecular compositions for treating ocular conditions
US8821870B2 (en) * 2008-07-18 2014-09-02 Allergan, Inc. Method for treating atrophic age related macular degeneration
US9033911B2 (en) * 2010-08-05 2015-05-19 Forsight Vision4, Inc. Injector apparatus and method for drug delivery
CA2953698A1 (en) * 2014-06-28 2015-12-30 Kodiak Sciences Inc. Dual pdgf/vegf antagonists
WO2017117202A1 (en) * 2015-12-29 2017-07-06 Oncobiologics, Inc. Buffered formulations of bevacizumab
CN106924184B (en) * 2017-03-29 2020-07-17 烟台大学 Multivesicular liposome for ocular vitreous injection and preparation method thereof

Also Published As

Publication number Publication date
US20210230261A1 (en) 2021-07-29
CN112543645A (en) 2021-03-23
EP3781199A1 (en) 2021-02-24
AU2019256289A1 (en) 2020-11-12
JP2021522180A (en) 2021-08-30
CA3097123A1 (en) 2019-10-24
BR112020021255A2 (en) 2021-02-02
KR20210011923A (en) 2021-02-02
WO2019204380A1 (en) 2019-10-24
MX2020010968A (en) 2021-01-08
IL278041A (en) 2020-11-30

Similar Documents

Publication Publication Date Title
IL278041A (en) Buffered formulations of bevacizumab for use of treating diseases
HK1258588A1 (en) Compounds and formulations for treating ophthalmic diseases
IL274938A (en) Novel compounds and pharmaceutical compositions thereof for the treatment of diseases
IL276383B1 (en) Treatment of ophthalmologic diseases
ZA202007055B (en) Compositions for the treatment of skin conditions
ZA202006610B (en) Compositions for the treatment of skin conditions
ZA201906213B (en) Compounds and methods for the treatment of parasitic diseases
IL280163A (en) Mitochondrial augmentation therapy for primary mitochondrial diseases
ZA202006234B (en) Compositions and methods for the treatment of neurological diseases
ZA202101587B (en) Protein for treatment of inflammatory diseases
IL279397A (en) Novel compounds and pharmaceutical compositions thereof for the treatment of diseases
IL287796A (en) Compositions and methods for the treatment of atpase-mediated diseases
IL282643A (en) Combination therapy for treatment of hematological diseases
EP3685840A4 (en) Compound pharmaceutical composition for treating inflammatory skin diseases
EP3846830A4 (en) Methods and compositions for treating musculoskeletal diseases
ZA202006264B (en) Stable formulations of therapeutic antibody
GB201820018D0 (en) Therapeutic hydrogel compositions
EP3849591A4 (en) Methods and compositions for treating skin diseases
EP3744347A4 (en) Composition for skin diseases treatment use
GB201805100D0 (en) Treatment of sarcopenic diseases
KR102324922B9 (en) Pharmaceutical composition comprising osteocalcin for preventing or treating inflammatory diseases
KR20180085033A (en) PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT OF SKIN DISEASES
IL280952A (en) Methods and compositions for drugs to treat ophthalmic diseases
GB201909438D0 (en) Treatment of diseases
SG11202010034WA (en) TREATMENT OF SKIN DISEASES OR DISORDERS BY DELIVERY OF ANTI-OSMRß ANTIBODY