SG11202009695QA - Anti-hla-g antibodies and use thereof - Google Patents

Anti-hla-g antibodies and use thereof

Info

Publication number
SG11202009695QA
SG11202009695QA SG11202009695QA SG11202009695QA SG11202009695QA SG 11202009695Q A SG11202009695Q A SG 11202009695QA SG 11202009695Q A SG11202009695Q A SG 11202009695QA SG 11202009695Q A SG11202009695Q A SG 11202009695QA SG 11202009695Q A SG11202009695Q A SG 11202009695QA
Authority
SG
Singapore
Prior art keywords
hla
antibodies
Prior art date
Application number
SG11202009695QA
Inventor
Stefan Dengl
Sebastian Fenn
Jens Fischer
Andreas Hinz
Claudia Kirstenpfad
Stefan Klostermann
Joerg Moelleken
Georg Tiefenthaler
Sabine Hoves
Alexander Bujotzek
Meher Majety
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of SG11202009695QA publication Critical patent/SG11202009695QA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2833Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against MHC-molecules, e.g. HLA-molecules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
SG11202009695QA 2018-04-18 2019-04-17 Anti-hla-g antibodies and use thereof SG11202009695QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18168011 2018-04-18
PCT/EP2019/060007 WO2019202040A1 (en) 2018-04-18 2019-04-17 Anti-hla-g antibodies and use thereof

Publications (1)

Publication Number Publication Date
SG11202009695QA true SG11202009695QA (en) 2020-11-27

Family

ID=62025723

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202009695QA SG11202009695QA (en) 2018-04-18 2019-04-17 Anti-hla-g antibodies and use thereof

Country Status (20)

Country Link
US (1) US20210147553A1 (en)
EP (1) EP3781593A1 (en)
JP (1) JP7186239B2 (en)
KR (1) KR102608672B1 (en)
CN (1) CN112004831B (en)
AR (1) AR114789A1 (en)
AU (1) AU2019254596A1 (en)
BR (1) BR112020020588A2 (en)
CA (1) CA3094895A1 (en)
CL (1) CL2020002540A1 (en)
CO (1) CO2020012347A2 (en)
CR (1) CR20200483A (en)
IL (1) IL277308A (en)
MA (1) MA52284A (en)
MX (1) MX2020010951A (en)
PE (1) PE20201419A1 (en)
SG (1) SG11202009695QA (en)
TW (1) TW201945395A (en)
WO (1) WO2019202040A1 (en)
ZA (1) ZA202006066B (en)

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PE20211604A1 (en) 2018-07-09 2021-08-23 Five Prime Therapeutics Inc ILT4 UNION ANTIBODIES
AR116526A1 (en) 2018-09-27 2021-05-19 Tizona Therapeutics ANTI-HLA-G ANTIBODIES, COMPOSITIONS INCLUDING ANTI-HLA-G ANTIBODIES AND METHODS OF USE OF ANTI-HLA-G ANTIBODIES
CN113528448B (en) * 2020-04-14 2023-01-24 同济大学 Construction method of human embryonic stem cells
KR20230120665A (en) 2020-12-17 2023-08-17 에프. 호프만-라 로슈 아게 Anti-HLA-G Antibodies and Uses Thereof
US20220306747A1 (en) * 2021-03-24 2022-09-29 China Medical University Hospital Anti-tumor antigen nanobody and nucleic acid encoding sequence thereof, and uses of the same
GB202111905D0 (en) 2021-08-19 2021-10-06 UCB Biopharma SRL Antibodies
WO2023182861A1 (en) * 2022-03-25 2023-09-28 에이치케이이노엔 주식회사 Anti-hla-g chimeric antigen receptor, and use thereof
WO2023182866A1 (en) * 2022-03-25 2023-09-28 에이치케이이노엔 주식회사 Hla-g-specific antibody and use thereof
CN115894687A (en) * 2022-03-31 2023-04-04 台州恩泽医疗中心(集团) Monoclonal antibody for resisting HLA-G1, -G2, -G5 and HLA-G6 isomer molecules and application thereof

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Also Published As

Publication number Publication date
CO2020012347A2 (en) 2020-10-30
CR20200483A (en) 2020-11-17
IL277308A (en) 2020-10-29
KR102608672B1 (en) 2023-11-30
AU2019254596A1 (en) 2020-10-29
BR112020020588A2 (en) 2021-01-12
JP7186239B2 (en) 2022-12-08
MA52284A (en) 2021-02-24
ZA202006066B (en) 2021-09-29
MX2020010951A (en) 2020-11-09
JP2021521791A (en) 2021-08-30
KR20210005080A (en) 2021-01-13
CA3094895A1 (en) 2019-10-24
TW201945395A (en) 2019-12-01
AR114789A1 (en) 2020-10-14
CN112004831A (en) 2020-11-27
PE20201419A1 (en) 2020-12-09
EP3781593A1 (en) 2021-02-24
CN112004831B (en) 2024-04-09
CL2020002540A1 (en) 2021-01-22
US20210147553A1 (en) 2021-05-20
WO2019202040A1 (en) 2019-10-24

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