SG11202006470RA - Use of 5-fluoro-4-(4-fluoro-2-methoxyphenyl)-n-{4-[(s-methylsulfonimidoyl)methyl]pyridin-2-yl}pyridin-2-amine for treating diffuse large b-cell lymphoma - Google Patents

Use of 5-fluoro-4-(4-fluoro-2-methoxyphenyl)-n-{4-[(s-methylsulfonimidoyl)methyl]pyridin-2-yl}pyridin-2-amine for treating diffuse large b-cell lymphoma

Info

Publication number
SG11202006470RA
SG11202006470RA SG11202006470RA SG11202006470RA SG11202006470RA SG 11202006470R A SG11202006470R A SG 11202006470RA SG 11202006470R A SG11202006470R A SG 11202006470RA SG 11202006470R A SG11202006470R A SG 11202006470RA SG 11202006470R A SG11202006470R A SG 11202006470RA
Authority
SG
Singapore
Prior art keywords
pyridin
fluoro
methylsulfonimidoyl
methoxyphenyl
amine
Prior art date
Application number
SG11202006470RA
Inventor
Arne Scholz
Original Assignee
Bayer Ag
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag, Bayer Pharma AG filed Critical Bayer Ag
Publication of SG11202006470RA publication Critical patent/SG11202006470RA/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
SG11202006470RA 2018-02-13 2019-02-12 Use of 5-fluoro-4-(4-fluoro-2-methoxyphenyl)-n-{4-[(s-methylsulfonimidoyl)methyl]pyridin-2-yl}pyridin-2-amine for treating diffuse large b-cell lymphoma SG11202006470RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18156576 2018-02-13
PCT/EP2019/053407 WO2019158517A1 (en) 2018-02-13 2019-02-12 Use of 5-fluoro-4-(4-fluoro-2-methoxyphenyl)-n-{4-[(s-methylsulfonimidoyl)methyl]pyridin-2-yl}pyridin-2-amine for treating diffuse large b-cell lymphoma

Publications (1)

Publication Number Publication Date
SG11202006470RA true SG11202006470RA (en) 2020-08-28

Family

ID=61223765

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202006470RA SG11202006470RA (en) 2018-02-13 2019-02-12 Use of 5-fluoro-4-(4-fluoro-2-methoxyphenyl)-n-{4-[(s-methylsulfonimidoyl)methyl]pyridin-2-yl}pyridin-2-amine for treating diffuse large b-cell lymphoma

Country Status (16)

Country Link
US (1) US11701347B2 (en)
EP (1) EP3752487A1 (en)
JP (1) JP7280286B2 (en)
KR (1) KR20200119800A (en)
CN (1) CN111727183B (en)
AU (1) AU2019221019A1 (en)
BR (1) BR112020016389A2 (en)
CA (1) CA3090843A1 (en)
CL (1) CL2020002087A1 (en)
EA (1) EA202091894A1 (en)
IL (1) IL276437B2 (en)
JO (1) JOP20200196A1 (en)
MA (1) MA51820A (en)
MX (1) MX2020008447A (en)
SG (1) SG11202006470RA (en)
WO (1) WO2019158517A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2020008447A (en) 2018-02-13 2020-09-28 Bayer Ag Use of 5-fluoro-4-(4-fluoro-2-methoxyphenyl)-n-{4-[(s-methylsulfo nimidoyl)methyl]pyridin-2-yl}pyridin-2-amine for treating diffuse large b-cell lymphoma.

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Also Published As

Publication number Publication date
CN111727183B (en) 2023-12-29
EA202091894A1 (en) 2020-12-28
MA51820A (en) 2021-05-19
AU2019221019A1 (en) 2020-07-23
JOP20200196A1 (en) 2020-08-13
BR112020016389A2 (en) 2020-12-15
CN111727183A (en) 2020-09-29
IL276437B2 (en) 2024-03-01
CA3090843A1 (en) 2019-08-22
JP7280286B2 (en) 2023-05-23
US20210015806A1 (en) 2021-01-21
US11701347B2 (en) 2023-07-18
MX2020008447A (en) 2020-09-28
CL2020002087A1 (en) 2020-12-11
EP3752487A1 (en) 2020-12-23
JP2021514386A (en) 2021-06-10
IL276437B1 (en) 2023-11-01
KR20200119800A (en) 2020-10-20
WO2019158517A1 (en) 2019-08-22
IL276437A (en) 2020-09-30

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