SG11202006410WA - Methods for the quantitation of polypeptides - Google Patents

Methods for the quantitation of polypeptides

Info

Publication number
SG11202006410WA
SG11202006410WA SG11202006410WA SG11202006410WA SG11202006410WA SG 11202006410W A SG11202006410W A SG 11202006410WA SG 11202006410W A SG11202006410W A SG 11202006410WA SG 11202006410W A SG11202006410W A SG 11202006410WA SG 11202006410W A SG11202006410W A SG 11202006410WA
Authority
SG
Singapore
Prior art keywords
quantitation
polypeptides
methods
Prior art date
Application number
SG11202006410WA
Inventor
Christopher Morgan
Xiaokui Zhang
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of SG11202006410WA publication Critical patent/SG11202006410WA/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • G01N33/6857Antibody fragments
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2560/00Chemical aspects of mass spectrometric analysis of biological material

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
SG11202006410WA 2018-01-12 2019-01-11 Methods for the quantitation of polypeptides SG11202006410WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862617080P 2018-01-12 2018-01-12
PCT/US2019/013373 WO2019140320A1 (en) 2018-01-12 2019-01-11 Methods for the quantitation of polypeptides

Publications (1)

Publication Number Publication Date
SG11202006410WA true SG11202006410WA (en) 2020-08-28

Family

ID=65444324

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202006410WA SG11202006410WA (en) 2018-01-12 2019-01-11 Methods for the quantitation of polypeptides

Country Status (13)

Country Link
US (2) US11067584B2 (en)
EP (1) EP3737949A1 (en)
JP (2) JP7394767B2 (en)
KR (1) KR20200109333A (en)
CN (1) CN111801580A (en)
AU (1) AU2019206648A1 (en)
BR (1) BR112020013325A2 (en)
CA (1) CA3088107A1 (en)
IL (1) IL275536A (en)
MX (1) MX2020007444A (en)
SG (1) SG11202006410WA (en)
WO (1) WO2019140320A1 (en)
ZA (1) ZA202003701B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3088107A1 (en) 2018-01-12 2019-07-18 Genzyme Corporation Methods for the quantitation of polypeptides

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5731168A (en) 1995-03-01 1998-03-24 Genentech, Inc. Method for making heteromultimeric polypeptides
US7632686B2 (en) 2002-10-03 2009-12-15 Anderson Forschung Group High sensitivity quantitation of peptides by mass spectrometry
JP2006033413A (en) * 2004-07-15 2006-02-02 Daishinku Corp Piezoelectric vibration device
CA2646965C (en) 2006-03-24 2016-06-21 Jonathan H. Davis Engineered heterodimeric protein domains
EP2035456A1 (en) 2006-06-22 2009-03-18 Novo Nordisk A/S Production of bispecific antibodies
EP2050764A1 (en) 2007-10-15 2009-04-22 sanofi-aventis Novel polyvalent bispecific antibody format and uses thereof
US9266967B2 (en) 2007-12-21 2016-02-23 Hoffmann-La Roche, Inc. Bivalent, bispecific antibodies
US20090162359A1 (en) 2007-12-21 2009-06-25 Christian Klein Bivalent, bispecific antibodies
US8227577B2 (en) 2007-12-21 2012-07-24 Hoffman-La Roche Inc. Bivalent, bispecific antibodies
US8242247B2 (en) 2007-12-21 2012-08-14 Hoffmann-La Roche Inc. Bivalent, bispecific antibodies
EP2235064B1 (en) 2008-01-07 2015-11-25 Amgen Inc. Method for making antibody fc-heterodimeric molecules using electrostatic steering effects
BRPI0910482A2 (en) 2008-04-29 2019-09-24 Abbott Lab double variable domain immunoglobins and their uses
JP2011523853A (en) 2008-06-03 2011-08-25 アボット・ラボラトリーズ Dual variable domain immunoglobulins and uses thereof
JP5723769B2 (en) 2008-06-03 2015-05-27 アッヴィ・インコーポレイテッド Dual variable domain immunoglobulins and uses thereof
RU2545783C9 (en) 2009-04-27 2016-02-27 Мерц Фарма Гмбх Унд Ко. Кгаа Agents and methods for measuring polypeptide neurotoxin and its catalytic and proteolytic activities
KR102152109B1 (en) 2010-04-20 2020-09-07 젠맵 에이/에스 Heterodimeric antibody fc-containing proteins and methods for production thereof
AU2011293253B2 (en) 2010-08-26 2014-12-11 Abbvie Inc. Dual variable domain immunoglobulins and uses thereof
TWI588156B (en) 2011-03-28 2017-06-21 賽諾菲公司 Dual variable region antibody-like binding proteins having cross-over binding region orientation
MX2013013054A (en) 2011-05-12 2014-02-20 Genentech Inc Multiple reaction monitoring lc-ms/ms method to detect therapeutic antibodies in animal samples using framework signature peptides.
CA2942769A1 (en) * 2014-03-19 2015-09-24 Genzyme Corporation Site-specific glycoengineering of targeting moieties
CN107405399B (en) * 2015-01-02 2022-02-08 武田药品工业株式会社 Bispecific antibodies against plasma kallikrein and factor XII
CN107428835B (en) 2015-01-23 2021-11-26 赛诺菲 anti-CD 3 antibodies, anti-CD 123 antibodies, and bispecific antibodies that specifically bind to CD3 and/or CD123
BR112017017854A2 (en) * 2015-03-09 2018-04-10 Shimadzu Corporation method for detecting monoclonal antibody using mass spectrometry
CN116789841A (en) 2015-10-25 2023-09-22 赛诺菲 Trispecific and/or trivalent binding proteins for the prevention or treatment of HIV infection
CR20180539A (en) * 2016-04-13 2019-02-15 Sanofi Sa THREE-SPECIFIC AND / OR TRIVAL UNION PROTEINS
US11067583B2 (en) * 2016-05-25 2021-07-20 University Of Maryland, Baltimore Methods of making active antibodies from biological fluids
CA3088107A1 (en) 2018-01-12 2019-07-18 Genzyme Corporation Methods for the quantitation of polypeptides

Also Published As

Publication number Publication date
ZA202003701B (en) 2021-10-27
JP2021510813A (en) 2021-04-30
AU2019206648A1 (en) 2020-07-16
WO2019140320A1 (en) 2019-07-18
JP7394767B2 (en) 2023-12-08
KR20200109333A (en) 2020-09-22
US11067584B2 (en) 2021-07-20
IL275536A (en) 2020-08-31
BR112020013325A2 (en) 2020-12-01
RU2020124746A3 (en) 2022-03-29
US11754573B2 (en) 2023-09-12
MX2020007444A (en) 2020-09-14
CA3088107A1 (en) 2019-07-18
RU2020124746A (en) 2022-02-14
US20220003780A1 (en) 2022-01-06
JP2023171846A (en) 2023-12-05
EP3737949A1 (en) 2020-11-18
US20190234963A1 (en) 2019-08-01
CN111801580A (en) 2020-10-20

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