SG11202005896WA - Esketamine for the treatment of depression - Google Patents
Esketamine for the treatment of depressionInfo
- Publication number
- SG11202005896WA SG11202005896WA SG11202005896WA SG11202005896WA SG11202005896WA SG 11202005896W A SG11202005896W A SG 11202005896WA SG 11202005896W A SG11202005896W A SG 11202005896WA SG 11202005896W A SG11202005896W A SG 11202005896WA SG 11202005896W A SG11202005896W A SG 11202005896WA
- Authority
- SG
- Singapore
- Prior art keywords
- esketamine
- depression
- treatment
- Prior art date
Links
- YQEZLKZALYSWHR-ZDUSSCGKSA-N (S)-ketamine Chemical compound C=1C=CC=C(Cl)C=1[C@@]1(NC)CCCCC1=O YQEZLKZALYSWHR-ZDUSSCGKSA-N 0.000 title 1
- 208000020401 Depressive disease Diseases 0.000 title 1
- 229960000450 esketamine Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Otolaryngology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762609504P | 2017-12-22 | 2017-12-22 | |
| US201862663219P | 2018-04-26 | 2018-04-26 | |
| US201862663206P | 2018-04-26 | 2018-04-26 | |
| US201862667406P | 2018-05-04 | 2018-05-04 | |
| US201862675846P | 2018-05-24 | 2018-05-24 | |
| US201862755905P | 2018-11-05 | 2018-11-05 | |
| PCT/US2018/066143 WO2019126108A1 (en) | 2017-12-22 | 2018-12-18 | Esketamine for the treatment of depression |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202005896WA true SG11202005896WA (en) | 2020-07-29 |
Family
ID=65003585
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202005896WA SG11202005896WA (en) | 2017-12-22 | 2018-12-18 | Esketamine for the treatment of depression |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US11707440B2 (en) |
| EP (1) | EP3501542A1 (en) |
| JP (2) | JP2021506924A (en) |
| KR (2) | KR20240011237A (en) |
| CN (2) | CN112423789A (en) |
| AU (1) | AU2018282466A1 (en) |
| BR (1) | BR112020012473A2 (en) |
| CA (1) | CA3086478A1 (en) |
| IL (1) | IL275482A (en) |
| JO (1) | JOP20200156A1 (en) |
| MA (1) | MA47719A (en) |
| MX (2) | MX2020006650A (en) |
| PH (1) | PH12020500555A1 (en) |
| SG (1) | SG11202005896WA (en) |
| TW (1) | TW202415363A (en) |
| WO (1) | WO2019126108A1 (en) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG10201802104QA (en) | 2013-03-15 | 2018-05-30 | Janssen Pharmaceutica Nv | Pharmaceutical composition of s-ketamine hydrochloride |
| CA2961208A1 (en) | 2014-09-15 | 2016-03-24 | Janssen Pharmaceutica Nv | Val66met (snp rs6265) genotype specific dosing regimens and methods for the treatment of depression |
| US20200009081A1 (en) | 2017-09-13 | 2020-01-09 | Janssen Pharmaceutica N.V. | Delivery Of Esketamine For The Treatment Of Depression |
| KR20240011237A (en) | 2017-12-22 | 2024-01-25 | 얀센 파마슈티카 엔브이 | Esketamine for the treatment of depression |
| CA3103440A1 (en) | 2018-06-27 | 2020-01-02 | Clexio Biosciences Ltd. | Method of treating major depressive disorder |
| JP2022504036A (en) | 2018-10-05 | 2022-01-13 | クレキシオ バイオサイエンシーズ エルティーディー． | Esketamine dosing regimen for the treatment of major depressive disorder |
| CA3131929A1 (en) * | 2019-03-05 | 2020-09-10 | Janssen Pharmaceuticals, Inc. | Esketamine for the treatment of depression |
| US20220151955A1 (en) * | 2019-08-05 | 2022-05-19 | The Ketamine Research Foundation | Ketamine for the treatment of postpartum symptoms and disorders |
| JP2022546456A (en) * | 2019-08-28 | 2022-11-04 | ヤンセン ファーマシューティカルズ，インコーポレーテッド | Esketamine for the treatment of patients with major depressive disorder including suicidal tendencies |
| EP4028085A4 (en) * | 2019-09-13 | 2023-10-04 | Janssen Pharmaceuticals, Inc. | Intranasal administration of esketamine |
| TW202135787A (en) | 2019-12-12 | 2021-10-01 | 比利時商健生藥品公司 | Esketamine formulations and methods for preparation and storage |
| WO2021137148A1 (en) | 2019-12-30 | 2021-07-08 | Clexio Biosciences Ltd. | Dosage regime with esketamine for treating neuropsychiatric or neurological conditions |
| CA3199076A1 (en) * | 2020-10-22 | 2022-04-28 | Tonix Pharmaceuticals Holding Corp. | Randomization honoring methods to assess the significance of interventions on outcomes in disorders |
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| JPS632932A (en) | 1986-06-23 | 1988-01-07 | Teijin Ltd | Powdery composition for nasal administration |
| US5002935A (en) | 1987-12-30 | 1991-03-26 | University Of Florida | Improvements in redox systems for brain-targeted drug delivery |
| US4994467A (en) | 1989-05-31 | 1991-02-19 | Zimmerman Andrew W | Treating autism and other developmental disorders in children with NMDA receptor antagonists |
| DE4312016A1 (en) | 1993-04-13 | 1994-10-20 | Goedecke Ag | Stable ketamine solutions |
| US5543434A (en) | 1994-02-25 | 1996-08-06 | Weg; Stuart L. | Nasal administration of ketamine to manage pain |
| DE69629108T2 (en) | 1995-02-24 | 2004-04-22 | Weg, Stuart L. | APPLICATION OF KETAMINE FOR DETOXIFICATION |
| CA2230690C (en) | 1995-08-30 | 2008-12-23 | Stuart L. Weg | Administration of ketamine to manage pain and to reduce drug dependency |
| FR2739294B1 (en) | 1995-09-29 | 1998-01-16 | Lhd Lab Hygiene Dietetique | NASAL SAFETY TIP |
| DE19619665C2 (en) | 1996-05-15 | 2001-03-08 | Goedecke Ag | Racemate separation of ketamine |
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| FR2764807B1 (en) | 1997-06-18 | 1999-08-20 | Valois Sa | NASAL DISPENSING DEVICE FOR A FLUID OR POWDERY PRODUCT |
| CN1205922C (en) | 1998-07-24 | 2005-06-15 | 柳署弘 | Preparation of aqueous clear solution dosage forms with bile acids |
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| US6176242B1 (en) | 1999-04-30 | 2001-01-23 | Medtronic Inc | Method of treating manic depression by brain infusion |
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| EP1328214A4 (en) | 2000-09-20 | 2009-07-29 | Shahinian Lee Jr | Self-preserved nasal, inhalable, and topical ophthalmic preparations and medications |
| US6881731B1 (en) | 2000-10-23 | 2005-04-19 | Shanbrom Technologies, Llc | Enhancers for microbiological disinfection |
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| JP2009530385A (en) | 2006-03-22 | 2009-08-27 | マウント シナイ スクール オブ メディシン | Intranasal ketamine for the treatment of depression |
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| JP2009538331A (en) | 2006-05-22 | 2009-11-05 | ヴァンダ ファーマシューティカルズ インコーポレイテッド | Treatment for depression disorders |
| DE102007009888A1 (en) | 2007-02-28 | 2008-09-04 | Hermann, Holger Lars, Dr. | Use of S-(+)-ketamine for treating depression, which is therapy-refractive depression, preferably depressive episode, relapsing disorder and bipolar affective disorder |
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| US10098854B2 (en) * | 2014-08-13 | 2018-10-16 | Janssen Pharmaceutica Nv | Method for the treatment of depression |
| CA2961208A1 (en) | 2014-09-15 | 2016-03-24 | Janssen Pharmaceutica Nv | Val66met (snp rs6265) genotype specific dosing regimens and methods for the treatment of depression |
| EP3240422A1 (en) | 2014-12-31 | 2017-11-08 | Icahn School of Medicine at Mount Sinai | Method of maintaining the anti-depressant effect of ketamine with lithium |
| CN104798728A (en) | 2015-05-08 | 2015-07-29 | 南京中医药大学 | Creation method and applications of postpartum depression animal models |
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| US20160338977A1 (en) | 2015-05-20 | 2016-11-24 | Janssen Pharmaceutica Nv | Methods and kits for treating depression |
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| US20180296478A1 (en) | 2016-02-12 | 2018-10-18 | Synergistic Therapeutics, Llc | Sublingual antidepressant and antianxiety tablet |
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| KR20240011237A (en) | 2017-12-22 | 2024-01-25 | 얀센 파마슈티카 엔브이 | Esketamine for the treatment of depression |
-
2018
- 2018-12-18 KR KR1020247000937A patent/KR20240011237A/en active Application Filing
- 2018-12-18 SG SG11202005896WA patent/SG11202005896WA/en unknown
- 2018-12-18 CN CN201880090058.6A patent/CN112423789A/en active Pending
- 2018-12-18 JP JP2020534520A patent/JP2021506924A/en active Pending
- 2018-12-18 US US16/956,403 patent/US11707440B2/en active Active
- 2018-12-18 CN CN202311355796.8A patent/CN117531017A/en active Pending
- 2018-12-18 WO PCT/US2018/066143 patent/WO2019126108A1/en active Application Filing
- 2018-12-18 MX MX2020006650A patent/MX2020006650A/en unknown
- 2018-12-18 JO JOP/2020/0156A patent/JOP20200156A1/en unknown
- 2018-12-18 KR KR1020207021196A patent/KR20200113197A/en not_active Application Discontinuation
- 2018-12-18 CA CA3086478A patent/CA3086478A1/en active Pending
- 2018-12-18 BR BR112020012473-7A patent/BR112020012473A2/en unknown
- 2018-12-21 TW TW112130258A patent/TW202415363A/en unknown
- 2018-12-21 AU AU2018282466A patent/AU2018282466A1/en active Pending
- 2018-12-21 EP EP18215651.3A patent/EP3501542A1/en active Pending
- 2018-12-21 MA MA047719A patent/MA47719A/en unknown
-
2020
- 2020-06-18 PH PH12020500555A patent/PH12020500555A1/en unknown
- 2020-06-18 IL IL275482A patent/IL275482A/en unknown
- 2020-07-13 MX MX2023012450A patent/MX2023012450A/en unknown
-
2023
- 2023-07-05 US US18/347,393 patent/US20240000728A1/en active Pending
- 2023-10-06 JP JP2023174444A patent/JP2024001204A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR20200113197A (en) | 2020-10-06 |
| AU2018282466A1 (en) | 2019-07-11 |
| TW201940162A (en) | 2019-10-16 |
| EP3501542A1 (en) | 2019-06-26 |
| BR112020012473A2 (en) | 2020-11-24 |
| CN112423789A (en) | 2021-02-26 |
| MX2023012450A (en) | 2023-10-31 |
| PH12020500555A1 (en) | 2021-05-17 |
| JP2021506924A (en) | 2021-02-22 |
| IL275482A (en) | 2020-08-31 |
| MX2020006650A (en) | 2020-11-06 |
| RU2020123893A (en) | 2022-01-24 |
| CN117531017A (en) | 2024-02-09 |
| US20210386688A1 (en) | 2021-12-16 |
| RU2020123893A3 (en) | 2022-04-29 |
| WO2019126108A1 (en) | 2019-06-27 |
| US11707440B2 (en) | 2023-07-25 |
| CA3086478A1 (en) | 2019-06-27 |
| JOP20200156A1 (en) | 2022-10-30 |
| US20240000728A1 (en) | 2024-01-04 |
| TW202415363A (en) | 2024-04-16 |
| KR20240011237A (en) | 2024-01-25 |
| MA47719A (en) | 2020-01-15 |
| JP2024001204A (en) | 2024-01-09 |
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