SG11202004540QA - Stable ascorbic acid compositions and methods of using the same - Google Patents

Stable ascorbic acid compositions and methods of using the same

Info

Publication number
SG11202004540QA
SG11202004540QA SG11202004540QA SG11202004540QA SG11202004540QA SG 11202004540Q A SG11202004540Q A SG 11202004540QA SG 11202004540Q A SG11202004540Q A SG 11202004540QA SG 11202004540Q A SG11202004540Q A SG 11202004540QA SG 11202004540Q A SG11202004540Q A SG 11202004540QA
Authority
SG
Singapore
Prior art keywords
methods
same
ascorbic acid
acid compositions
stable ascorbic
Prior art date
Application number
SG11202004540QA
Inventor
Dan Copeland
Carolyn Durham
Original Assignee
Renovion Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Renovion Inc filed Critical Renovion Inc
Publication of SG11202004540QA publication Critical patent/SG11202004540QA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06Tripeptides
    • A61K38/063Glutathione
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4418Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
SG11202004540QA 2017-11-17 2018-11-16 Stable ascorbic acid compositions and methods of using the same SG11202004540QA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762588300P 2017-11-17 2017-11-17
US201862684700P 2018-06-13 2018-06-13
PCT/US2018/061686 WO2019099946A1 (en) 2017-11-17 2018-11-16 Stable ascorbic acid compositions and methods of using the same

Publications (1)

Publication Number Publication Date
SG11202004540QA true SG11202004540QA (en) 2020-06-29

Family

ID=66539933

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202004540QA SG11202004540QA (en) 2017-11-17 2018-11-16 Stable ascorbic acid compositions and methods of using the same

Country Status (13)

Country Link
US (3) US11497786B2 (en)
EP (1) EP3710036A4 (en)
JP (2) JP7339955B2 (en)
KR (1) KR20200089702A (en)
CN (1) CN111615395A (en)
AU (1) AU2018367674A1 (en)
BR (1) BR112020009910A2 (en)
CA (1) CA3082900A1 (en)
IL (1) IL274635A (en)
MX (2) MX2020005087A (en)
PH (1) PH12020550645A1 (en)
SG (1) SG11202004540QA (en)
WO (1) WO2019099946A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3541401A4 (en) 2016-11-17 2020-07-29 Renovion, Inc. Treatment of respiratory tract diseases and infections with glutathione compositions
SG11202004540QA (en) 2017-11-17 2020-06-29 Renovion Inc Stable ascorbic acid compositions and methods of using the same
CN111413492A (en) * 2020-04-30 2020-07-14 山东大学 Method and system for detecting novel coronavirus COVID-2019 pneumonia
EP3970718A1 (en) * 2020-09-18 2022-03-23 Charité - Universitätsmedizin Berlin New medical use of cystic fibrosis transmembrane conductance regulator (cftr) modulators
WO2023014887A1 (en) * 2021-08-04 2023-02-09 The Trustees Of Indiana University Methods of treating compromised lung function and assessing clinical improvement
CN113995744B (en) * 2021-10-13 2023-03-17 温州肯恩大学 Composition and antibacterial application thereof
WO2023133117A2 (en) * 2022-01-04 2023-07-13 Renovion, Inc. Aqueous solution comprising a glutathione salt
WO2023141237A1 (en) * 2022-01-20 2023-07-27 Cell and Molecular Tissue Engineering, LLC Methods and products to detect, minimize and treat trap-related tissue reactions and tissue injury associated with medical devices
WO2024016019A1 (en) * 2022-07-15 2024-01-18 Renovion, Inc. Compositions and methods for treatment of subjects suffering from a sars-cov-2 infection

Family Cites Families (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2606903A (en) 1944-03-29 1952-08-12 Physiological Chemicals Compan Ascorbic acid addition compound of sulfathiazole
US5070085A (en) 1987-04-10 1991-12-03 Oxycal Laboratories, Inc. Compositions and methods for administering therapeutically active compounds
US4968716A (en) 1987-04-10 1990-11-06 Oxycal Laboratories, Inc. Compositions and methods for administering therapeutically active compounds
US4861783A (en) 1988-04-26 1989-08-29 E. I. Du Pont De Nemours And Company 4-quinoline carboxylic acid derivatives useful for treating skin and muco-epithelial diseases
US5304724A (en) 1988-09-09 1994-04-19 Entravision, Inc. Tissue irrigating solution
US5238683A (en) 1989-11-24 1993-08-24 The United States Of America As Represented By The Department Of Health And Human Services Aerosol preparation of glutathione and a method for augmenting glutathione level in lungs
ATE144142T1 (en) 1991-01-10 1996-11-15 Transcend Therapeutics Inc USE OF THIAZOLIDINE-4-CARBOXYLATE DERIVATIVES FOR THE TREATMENT OF LUNG DISEASES
US6764693B1 (en) 1992-12-11 2004-07-20 Amaox, Ltd. Free radical quenching composition and a method to increase intracellular and/or extracellular antioxidants
US5626883A (en) 1994-04-15 1997-05-06 Metagenics, Inc. Ascorbic acid compositions providing enhanced human immune system activity
NZ335401A (en) 1996-11-01 2000-12-22 Xoma Corp Therapeutic uses of BPI protein products in cystic fibrosis patients
US6896899B2 (en) 1996-12-31 2005-05-24 Antioxidant Pharmaceuticals Corp. Pharmaceutical preparations of glutathione and methods of administration thereof
ATE448782T1 (en) 1996-12-31 2009-12-15 Antioxidant Pharmaceuticals Co PHARMACEUTICAL GLUTATHIONE PREPARATIONS AND METHODS OF ADMINISTRATION SAME
US5906811A (en) 1997-06-27 1999-05-25 Thione International, Inc. Intra-oral antioxidant preparations
US6415798B1 (en) 1997-09-19 2002-07-09 Thione International, Inc. Antioxidants to neutralize tobacco free radicals
US5829449A (en) 1997-09-19 1998-11-03 Thione International, Inc. Smoking products containing antioxidants
US6470894B2 (en) 1997-09-19 2002-10-29 Thione International, Inc. Glutathione, green tea, grape seed extract to neutralize tobacco free radicals
US6228347B1 (en) 1997-12-01 2001-05-08 Thione International, Inc. Antioxidant gel for gingival conditions
CA2339473A1 (en) 1998-08-04 2000-02-17 John V. Kosbab Nutrient and therapeutic compositions for the treatment of cancer
US6312734B1 (en) 1998-11-23 2001-11-06 Novelos Therapeutics, Inc. Methods for production of the oxidized glutathione composite with cis-diamminedichloroplatinum and pharmaceutical compositions based thereof regulating metabolism, proliferation, differentiation and apoptotic mechanisms for normal and transformed cells
KR100390630B1 (en) * 1999-07-02 2003-07-07 이희발 Peritoneal dialysis solutions containing antioxidants
DE19935763B4 (en) 1999-07-27 2006-03-02 Jenning, Volkhard, Dr. Composition of a redox system for the stabilization of retinoids in preparations for external use
US7045152B2 (en) 1999-09-08 2006-05-16 Duke University Treating pulmonary disorders with gaseous agent causing repletion of GSNO
US20020037855A1 (en) 2000-05-05 2002-03-28 Fritz Stanislaus Stabilized medicament containing cysteinyl derivatives
EP1282416A2 (en) 2000-05-19 2003-02-12 Progenics Pharmaceuticals, Inc. Dehydroascorbic acid formulations and uses thereof
US6601580B1 (en) 2000-06-28 2003-08-05 The General Hospital Corporation Enhancing therapeutic effectiveness of nitric oxide inhalation
US6485950B1 (en) 2000-07-14 2002-11-26 Council Of Scientific And Industrial Research Isozyme of autoclavable superoxide dismutase (SOD), a process for the identification and extraction of the SOD in cosmetic, food and pharmaceutical compositions
AU1122202A (en) 2000-10-16 2002-04-29 Univ Duke Therapeutic use of aerosolized s-nitrosoglutathione in cystic fibrosis
US20020165207A1 (en) 2001-05-02 2002-11-07 Richard Rosenbloom Compositions and methods for the treatment of diabetic neuropathy
WO2002053161A1 (en) 2000-12-29 2002-07-11 Alteon, Inc. Method for treating fibrotic diseases or other indications
DE60233140D1 (en) 2001-05-02 2009-09-10 Nitromed Inc NITROSED AND NITROSYLATED NEBIVOLOL AND ITS METABOLITES, COMPOSITIONS AND METHOD OF USE
EP1474158B1 (en) 2001-12-18 2009-10-14 Brassica Foundation for Chemoprotection Research, Inc. Prevention and treatment of oxidative stress disorders by compounds which elevate intracellular levels of glutathione or phase ii detoxification enzymes
AUPS019802A0 (en) 2002-01-31 2002-02-21 Chemstop Pty Ltd Nutrient formulation
US20040229815A1 (en) 2003-01-03 2004-11-18 Nagasawa Herbert T. Methods for reducing oxidative stress in a cell with a sulfhydryl protected glutathione prodrug
US9539367B2 (en) 2003-12-04 2017-01-10 University Of Iowa Research Foundation Gallium inhibits biofilm formation
US20050271726A1 (en) 2004-06-02 2005-12-08 Albert Crum Immune enhancing compositions and methods of use thereof
DE102004035113A1 (en) 2004-07-20 2006-02-16 Degussa Ag Composition for treating symptoms of cystic fibrosis comprises alpha-lipoic acid or a derivative thereof as the sole active ingredient
US8349359B2 (en) 2004-11-07 2013-01-08 Your Energy Systems, LLC Liposomal formulation for oral administration of glutathione (reduced)
ES2395555T3 (en) 2004-11-07 2013-02-13 Your Energy Systems, LLC Liposomal formulation for oral administration of glutathione (reduced)
CA2587883A1 (en) 2004-11-17 2006-05-26 Yissum Research Development Company Of The Hebrew University Of Jerusale M Use of polymer-lipid conjugates in the prevention and treatment of chronic pulmonary disease, allergic rhinitis and asthma
US8703198B2 (en) 2005-03-02 2014-04-22 Aquatrove Biosciences Water-based personal moisturizers and lubricants, in particular vaginal lubricants, and uses thereof
WO2006110552A2 (en) 2005-04-12 2006-10-19 Cleo Cosmetic And Pharmaceutical Co., Llc Composition and method for in vitro preservation of corneal tissues
US20060258599A1 (en) 2005-04-27 2006-11-16 Melanie Childers Methods and composition for the treatment of cystic fibrosis and related illnesses
WO2006125262A1 (en) 2005-05-24 2006-11-30 Environmental Biotechnology Crc Pty Limited Methods and compositions for regulating biofilm development
CA2620123C (en) 2005-08-24 2011-11-22 The Board Of Trustees Of The Leland Stanford Junior University Methods for treating and monitoring inflammation and redox imbalance in cystic fibrosis
AU2007249348C1 (en) 2006-05-10 2013-01-17 Laclede, Inc. Compositions and methods for enzymatic treatment of lung disorders
US20080008694A1 (en) 2006-07-05 2008-01-10 Elgebaly Salwa A Methods to prevent and treat diseases
US20100310541A1 (en) 2007-05-25 2010-12-09 Ironwood Pharmaceuticals, Inc. Compositions and Methods for Reducing the Toxicity of Certain Toxins
WO2009001884A1 (en) 2007-06-26 2008-12-31 Kyowa Hakko Bio Co., Ltd. Oxidized glutathione tablet
JP2011026204A (en) 2007-11-26 2011-02-10 Rei Furukawa Prophylactic and/or therapeutic composition for disease caused by inhalation of tobacco smoke
JP5406049B2 (en) 2008-02-05 2014-02-05 協和発酵バイオ株式会社 Method for improving storage stability of glutathione
US9289462B2 (en) 2008-09-17 2016-03-22 Terry Gage Method for medical treatment utilizing glutathione
FR2941374B1 (en) 2009-01-28 2011-03-11 Alaxia USE OF A SYNERGISTIC ASSOCIATION OF HYPOTHIOCYANITIS AND / OR HYPOHALITY IONS AND LACTOFERRIN FOR THE PREPARATION FOR THE TREATMENT OF MUCOVISCIDOSIS
WO2010099523A1 (en) 2009-02-27 2010-09-02 University Of Cincinnati Method of treating reactive airway disease
GB0908174D0 (en) 2009-05-13 2009-06-24 Isis Innovation Steroid containing composition and uses thereof
CN101987195B (en) 2009-08-06 2012-07-18 重庆市力扬医药开发有限公司 Reduced glutathione medicine absorbed through oral mucosa
IT1401504B1 (en) 2010-08-02 2013-07-26 Cattarini Mastelli COMPOSITION INCLUDING GLUTATION AND REDUCTASE AND OXIDIZED GLUTATION
WO2012027603A2 (en) 2010-08-26 2012-03-01 Clarity Products, Limited Liability Company Therapeutic consumable compositions for reduction of facial flush effect incident to alcohol consumption in persons with deficient activity of the aldehyde dehydrogenase gene-aldh2
GB201021992D0 (en) 2010-12-23 2011-02-02 Astrazeneca Ab Compound
CN102100904B (en) 2011-01-25 2013-04-24 成都卓阳生物科技有限公司 Reduced glutathione percutaneous absorption preparation and preparation method thereof
US10328152B2 (en) 2011-06-16 2019-06-25 Nayan Patel Method for stabilization and delivery of therapeutic molecules
US20130084336A1 (en) 2011-06-27 2013-04-04 Albert Einstein College Of Medicine Of Yeshiva University Enhanced nitric oxide delivery and uses thereof
CN102329370B (en) 2011-09-22 2015-07-22 山东金城医药化工股份有限公司 Method for preparing reduced glutathione monosodium salts
CA2925546C (en) 2012-10-29 2022-06-14 The University Of North Carolina At Chapel Hill Methods and compositions for treating mucosal tissue disorders
US20140234397A1 (en) 2013-02-15 2014-08-21 Lou Ann Brown Treatment of klebsiella pneumoniae with liposomally formulated glutathione
EP2956153A4 (en) 2013-02-15 2017-03-22 Your Energy Systems, LLC Treatment of evolving bacterial resistance diseases including klebsiella pneumoniae with liposomally formulated glutathione
ITPD20130052A1 (en) 2013-03-01 2014-09-02 Enologica Vason S P A VINIFICATION PROCEDURE AND PRODUCT FOR ENOLOGICAL USE ACT TO BE USED IN THE ABOVE WINE-MAKING PROCEDURE
WO2016037166A1 (en) 2014-09-07 2016-03-10 Yu Zhang Novel anti-oxidant compositions and methods of delivery
WO2016067283A1 (en) 2014-10-30 2016-05-06 Rice Howard Virucidal compositions comprising tannins for nasal and pulmonary administration
WO2016088116A1 (en) 2014-12-05 2016-06-09 University Health Network Use of antioxidants as radio-protective agents
US20160367620A1 (en) 2015-06-19 2016-12-22 Harry B. Demopoulos Glutathione
EP3484458A4 (en) 2016-07-16 2020-04-15 Lauranell Harrison Burch Methods for treating cystic fibrosis and other diseases affecting mucosal surfaces
EP3541401A4 (en) 2016-11-17 2020-07-29 Renovion, Inc. Treatment of respiratory tract diseases and infections with glutathione compositions
SG11202004540QA (en) * 2017-11-17 2020-06-29 Renovion Inc Stable ascorbic acid compositions and methods of using the same
EP3714881A4 (en) 2017-11-21 2021-09-01 Medoncare Pharmaceutical Co., Ltd Combination product comprising dicycloplatin and preparation method and use thereof
EA202091396A1 (en) 2017-12-07 2020-09-02 РИВЕН АйПи ХОЛДКО ЭлЭлСи COMPOSITIONS AND METHODS FOR TREATMENT OF METABOLIC CONDITIONS
AU2019365216A1 (en) 2018-10-23 2021-06-10 George Edward Hoag Composition and method for treating the lungs

Also Published As

Publication number Publication date
RU2020117840A3 (en) 2022-04-22
IL274635A (en) 2020-06-30
RU2020117840A (en) 2021-12-17
MX2020005087A (en) 2020-08-13
MX2023010248A (en) 2023-09-15
US11497786B2 (en) 2022-11-15
JP7339955B2 (en) 2023-09-06
US20230144527A1 (en) 2023-05-11
CN111615395A (en) 2020-09-01
JP2023110019A (en) 2023-08-08
WO2019099946A1 (en) 2019-05-23
AU2018367674A1 (en) 2020-06-04
US20200397849A1 (en) 2020-12-24
JP2021503497A (en) 2021-02-12
US20240131109A1 (en) 2024-04-25
CA3082900A1 (en) 2019-05-23
PH12020550645A1 (en) 2021-04-19
EP3710036A1 (en) 2020-09-23
KR20200089702A (en) 2020-07-27
US11890315B2 (en) 2024-02-06
BR112020009910A2 (en) 2020-11-03
EP3710036A4 (en) 2021-07-21

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