SG11202004332XA - Use of riluzole prodrugs to treat ataxias - Google Patents
Use of riluzole prodrugs to treat ataxiasInfo
- Publication number
- SG11202004332XA SG11202004332XA SG11202004332XA SG11202004332XA SG11202004332XA SG 11202004332X A SG11202004332X A SG 11202004332XA SG 11202004332X A SG11202004332X A SG 11202004332XA SG 11202004332X A SG11202004332X A SG 11202004332XA SG 11202004332X A SG11202004332X A SG 11202004332XA
- Authority
- SG
- Singapore
- Prior art keywords
- ataxias
- treat
- riluzole prodrugs
- riluzole
- prodrugs
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2063—Proteins, e.g. gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/485—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762584856P | 2017-11-12 | 2017-11-12 | |
US201862717948P | 2018-08-13 | 2018-08-13 | |
PCT/US2018/060232 WO2019094851A1 (en) | 2017-11-12 | 2018-11-11 | Use of riluzole prodrugs to treat ataxias |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202004332XA true SG11202004332XA (en) | 2020-06-29 |
Family
ID=66438598
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202004332XA SG11202004332XA (en) | 2017-11-12 | 2018-11-11 | Use of riluzole prodrugs to treat ataxias |
Country Status (13)
Country | Link |
---|---|
US (3) | US20210023061A1 (en) |
EP (1) | EP3706739A4 (en) |
JP (2) | JP7352542B2 (en) |
KR (1) | KR20200103658A (en) |
CN (1) | CN112292127A (en) |
AU (1) | AU2018364749C1 (en) |
BR (1) | BR112020009173A2 (en) |
CA (1) | CA3082096A1 (en) |
IL (1) | IL274532B1 (en) |
MX (1) | MX2020004678A (en) |
PH (1) | PH12020550583A1 (en) |
SG (1) | SG11202004332XA (en) |
WO (1) | WO2019094851A1 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RS62915B1 (en) | 2015-03-03 | 2022-03-31 | Biohaven Therapeutics Ltd | Riluzole prodrugs and their use |
WO2022155564A1 (en) * | 2021-01-18 | 2022-07-21 | Biohaven Therapeutics Ltd. | Use of riluzole prodrugs to treat alzheimer's disease |
WO2023081859A1 (en) * | 2021-11-04 | 2023-05-11 | Skyhawk Therapeutics, Inc. | Triazine amino derivatives for treating sca3 |
WO2023230451A2 (en) * | 2022-05-23 | 2023-11-30 | Biohaven Therapeutics Ltd. | Methods of treating spinocerebellar ataxias |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE208615T1 (en) | 1993-07-09 | 2001-11-15 | Scherer Corp R P | METHOD FOR PRODUCING FREEZE-DRIED MEDICINAL DOSAGE FORMS |
US5457895A (en) | 1993-10-01 | 1995-10-17 | R. P. Scherer Corporation | Method of identifying freeze-dried dosage forms |
US5837287A (en) | 1994-10-28 | 1998-11-17 | R P Scherer Corporation | Process for preparing solid pharmaceutical dosage forms |
AU736912B2 (en) | 1997-02-20 | 2001-08-02 | Therics, Inc. | Dosage form exhibiting rapid disperse properties, methods of use and process for the manufacture of same |
EP1001748B1 (en) | 1997-07-25 | 2006-04-19 | Alpex Pharma S.A. | A process for the preparation of a granulate suitable to the preparation of rapidly disintegrable mouth-soluble tablets |
ID29270A (en) | 1998-11-20 | 2001-08-16 | Rtp Pharma Inc | MICRO PARTICLES THAT ARE STABILIZED BY PHOSPHOLIPIDS THAT CAN SPREAD |
US6284270B1 (en) | 1999-08-04 | 2001-09-04 | Drugtech Corporation | Means for creating a mass having structural integrity |
US6316029B1 (en) | 2000-05-18 | 2001-11-13 | Flak Pharma International, Ltd. | Rapidly disintegrating solid oral dosage form |
US6982251B2 (en) | 2000-12-20 | 2006-01-03 | Schering Corporation | Substituted 2-azetidinones useful as hypocholesterolemic agents |
US6814978B2 (en) | 2000-12-29 | 2004-11-09 | Mcneil-Ppc, Inc. | Process for preparing a soft tablet |
US6509040B1 (en) | 2001-06-22 | 2003-01-21 | R.P. Scherer Corporation | Fast dispersing dosage forms essentially free of mammalian gelatin |
JP2005508939A (en) | 2001-10-12 | 2005-04-07 | エラン ファーマ インターナショナル,リミティド | Composition having combined immediate release and sustained release characteristics |
EP1485296B1 (en) | 2002-02-13 | 2011-07-20 | Michael K. Weibel | Drug dose - form and method of manufacture |
US7282217B1 (en) | 2003-08-29 | 2007-10-16 | Kv Pharmaceutical Company | Rapidly disintegrable tablets |
US8158152B2 (en) | 2005-11-18 | 2012-04-17 | Scidose Llc | Lyophilization process and products obtained thereby |
BRPI0620578A2 (en) | 2005-12-27 | 2011-12-06 | Jubilant Organosys Ltd | pharmaceutical composition that dissolves in the mouth and process for the preparation thereof |
CN101686942B (en) | 2007-06-27 | 2012-09-26 | 韩美药品株式会社 | Method for preparing rapidly disintegrating formulation for oral administration and apparatus for preparing and packing the same |
JP2011516489A (en) * | 2008-03-31 | 2011-05-26 | ユニバーシティ・オブ・サウス・フロリダ | Treatment of disease-induced ataxia and ataxia imbalance |
US8731842B2 (en) | 2008-10-31 | 2014-05-20 | The Invention Science Fund I, Llc | Compositions and methods for biological remodeling with frozen particle compositions |
US8256233B2 (en) | 2008-10-31 | 2012-09-04 | The Invention Science Fund I, Llc | Systems, devices, and methods for making or administering frozen particles |
US8313768B2 (en) | 2009-09-24 | 2012-11-20 | Mcneil-Ppc, Inc. | Manufacture of tablet having immediate release region and sustained release region |
RS62915B1 (en) * | 2015-03-03 | 2022-03-31 | Biohaven Therapeutics Ltd | Riluzole prodrugs and their use |
-
2018
- 2018-11-11 US US16/762,165 patent/US20210023061A1/en active Pending
- 2018-11-11 AU AU2018364749A patent/AU2018364749C1/en active Active
- 2018-11-11 CN CN201880073828.6A patent/CN112292127A/en active Pending
- 2018-11-11 IL IL274532A patent/IL274532B1/en unknown
- 2018-11-11 SG SG11202004332XA patent/SG11202004332XA/en unknown
- 2018-11-11 CA CA3082096A patent/CA3082096A1/en active Pending
- 2018-11-11 WO PCT/US2018/060232 patent/WO2019094851A1/en active Application Filing
- 2018-11-11 JP JP2020526149A patent/JP7352542B2/en active Active
- 2018-11-11 MX MX2020004678A patent/MX2020004678A/en unknown
- 2018-11-11 EP EP18876779.2A patent/EP3706739A4/en active Pending
- 2018-11-11 KR KR1020207016775A patent/KR20200103658A/en not_active Application Discontinuation
- 2018-11-11 BR BR112020009173-1A patent/BR112020009173A2/en unknown
-
2020
- 2020-05-08 PH PH12020550583A patent/PH12020550583A1/en unknown
-
2023
- 2023-07-17 US US18/353,850 patent/US20230355592A1/en active Pending
- 2023-07-17 US US18/353,840 patent/US20230390252A1/en active Pending
- 2023-09-15 JP JP2023149803A patent/JP2023175823A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
NZ765220A (en) | 2023-11-24 |
PH12020550583A1 (en) | 2021-05-31 |
KR20200103658A (en) | 2020-09-02 |
JP7352542B2 (en) | 2023-09-28 |
CN112292127A (en) | 2021-01-29 |
AU2018364749A1 (en) | 2020-07-02 |
US20230390252A1 (en) | 2023-12-07 |
US20230355592A1 (en) | 2023-11-09 |
MX2020004678A (en) | 2020-08-13 |
JP2021502392A (en) | 2021-01-28 |
CA3082096A1 (en) | 2019-05-16 |
BR112020009173A2 (en) | 2020-11-03 |
EP3706739A4 (en) | 2021-08-04 |
IL274532A (en) | 2020-06-30 |
AU2018364749B2 (en) | 2023-11-09 |
EP3706739A1 (en) | 2020-09-16 |
IL274532B1 (en) | 2024-01-01 |
JP2023175823A (en) | 2023-12-12 |
WO2019094851A1 (en) | 2019-05-16 |
AU2018364749C1 (en) | 2024-02-15 |
US20210023061A1 (en) | 2021-01-28 |
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