FR901228A
(en)
|
1943-01-16 |
1945-07-20 |
Deutsche Edelstahlwerke Ag |
Ring gap magnet system
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
US4943533A
(en)
|
1984-03-01 |
1990-07-24 |
The Regents Of The University Of California |
Hybrid cell lines that produce monoclonal antibodies to epidermal growth factor receptor
|
US6548640B1
(en)
|
1986-03-27 |
2003-04-15 |
Btg International Limited |
Altered antibodies
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
GB8607679D0
(en)
|
1986-03-27 |
1986-04-30 |
Winter G P |
Recombinant dna product
|
US6355476B1
(en)
|
1988-11-07 |
2002-03-12 |
Advanced Research And Technologyinc |
Nucleic acid encoding MIP-1α Lymphokine
|
US6362325B1
(en)
|
1988-11-07 |
2002-03-26 |
Advanced Research And Technology Institute, Inc. |
Murine 4-1BB gene
|
US6303121B1
(en)
|
1992-07-30 |
2001-10-16 |
Advanced Research And Technology |
Method of using human receptor protein 4-1BB
|
US6352694B1
(en)
|
1994-06-03 |
2002-03-05 |
Genetics Institute, Inc. |
Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells
|
US6905680B2
(en)
|
1988-11-23 |
2005-06-14 |
Genetics Institute, Inc. |
Methods of treating HIV infected subjects
|
US5858358A
(en)
|
1992-04-07 |
1999-01-12 |
The United States Of America As Represented By The Secretary Of The Navy |
Methods for selectively stimulating proliferation of T cells
|
US6534055B1
(en)
|
1988-11-23 |
2003-03-18 |
Genetics Institute, Inc. |
Methods for selectively stimulating proliferation of T cells
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
US5703055A
(en)
|
1989-03-21 |
1997-12-30 |
Wisconsin Alumni Research Foundation |
Generation of antibodies through lipid mediated DNA delivery
|
US5399346A
(en)
|
1989-06-14 |
1995-03-21 |
The United States Of America As Represented By The Department Of Health And Human Services |
Gene therapy
|
US5585362A
(en)
|
1989-08-22 |
1996-12-17 |
The Regents Of The University Of Michigan |
Adenovirus vectors for gene therapy
|
US5859205A
(en)
|
1989-12-21 |
1999-01-12 |
Celltech Limited |
Humanised antibodies
|
GB8928874D0
(en)
|
1989-12-21 |
1990-02-28 |
Celltech Ltd |
Humanised antibodies
|
US5061620A
(en)
|
1990-03-30 |
1991-10-29 |
Systemix, Inc. |
Human hematopoietic stem cell
|
DE69233482T2
(en)
|
1991-05-17 |
2006-01-12 |
Merck & Co., Inc. |
Method for reducing the immunogenicity of antibody variable domains
|
US5199942A
(en)
|
1991-06-07 |
1993-04-06 |
Immunex Corporation |
Method for improving autologous transplantation
|
JP4124480B2
(en)
|
1991-06-14 |
2008-07-23 |
ジェネンテック・インコーポレーテッド |
Immunoglobulin variants
|
US5851795A
(en)
|
1991-06-27 |
1998-12-22 |
Bristol-Myers Squibb Company |
Soluble CTLA4 molecules and uses thereof
|
ES2136092T3
(en)
|
1991-09-23 |
1999-11-16 |
Medical Res Council |
PROCEDURES FOR THE PRODUCTION OF HUMANIZED ANTIBODIES.
|
WO1993007105A1
(en)
|
1991-10-04 |
1993-04-15 |
Iit Research Institute |
Conversion of plastic waste to useful oils
|
GB9125768D0
(en)
|
1991-12-04 |
1992-02-05 |
Hale Geoffrey |
Therapeutic method
|
US5766886A
(en)
|
1991-12-13 |
1998-06-16 |
Xoma Corporation |
Modified antibody variable domains
|
DK1087013T3
(en)
|
1992-08-21 |
2009-05-11 |
Univ Bruxelles |
Immunoglobulins without light chains
|
US6005079A
(en)
|
1992-08-21 |
1999-12-21 |
Vrije Universiteit Brussels |
Immunoglobulins devoid of light chains
|
US5350674A
(en)
|
1992-09-04 |
1994-09-27 |
Becton, Dickinson And Company |
Intrinsic factor - horse peroxidase conjugates and a method for increasing the stability thereof
|
US5639641A
(en)
|
1992-09-09 |
1997-06-17 |
Immunogen Inc. |
Resurfacing of rodent antibodies
|
DE69329503T2
(en)
|
1992-11-13 |
2001-05-03 |
Idec Pharma Corp |
Therapeutic use of chimeric and labeled antibodies directed against a differentiation antigen, the expression of which is restricted to human B lymphocyte, for the treatment of B cell lymphoma
|
EP0699237B1
(en)
|
1994-03-17 |
2003-02-19 |
MERCK PATENT GmbH |
Anti-egfr single-chain fvs and anti-egfr antibodies
|
US7175843B2
(en)
|
1994-06-03 |
2007-02-13 |
Genetics Institute, Llc |
Methods for selectively stimulating proliferation of T cells
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
US7067318B2
(en)
|
1995-06-07 |
2006-06-27 |
The Regents Of The University Of Michigan |
Methods for transfecting T cells
|
US6692964B1
(en)
|
1995-05-04 |
2004-02-17 |
The United States Of America As Represented By The Secretary Of The Navy |
Methods for transfecting T cells
|
US5773292A
(en)
|
1995-06-05 |
1998-06-30 |
Cornell University |
Antibodies binding portions, and probes recognizing an antigen of prostate epithelial cells but not antigens circulating in the blood
|
US7060808B1
(en)
|
1995-06-07 |
2006-06-13 |
Imclone Systems Incorporated |
Humanized anti-EGF receptor monoclonal antibody
|
US5811097A
(en)
|
1995-07-25 |
1998-09-22 |
The Regents Of The University Of California |
Blockade of T lymphocyte down-regulation associated with CTLA-4 signaling
|
US6051227A
(en)
|
1995-07-25 |
2000-04-18 |
The Regents Of The University Of California, Office Of Technology Transfer |
Blockade of T lymphocyte down-regulation associated with CTLA-4 signaling
|
US6136311A
(en)
|
1996-05-06 |
2000-10-24 |
Cornell Research Foundation, Inc. |
Treatment and diagnosis of cancer
|
US6107090A
(en)
|
1996-05-06 |
2000-08-22 |
Cornell Research Foundation, Inc. |
Treatment and diagnosis of prostate cancer with antibodies to extracellur PSMA domains
|
DK0826696T3
(en)
|
1996-09-03 |
2002-09-23 |
Gsf Forschungszentrum Umwelt |
Use of bi- and trispecific antibodies to induce a tumor immunity
|
JP2001502325A
(en)
|
1996-10-11 |
2001-02-20 |
ブリストル―マイヤーズ・スクイブ・カンパニー |
Methods and compositions for immunomodulation
|
WO1999023221A2
(en)
|
1997-10-27 |
1999-05-14 |
Unilever Plc |
Multivalent antigen-binding proteins
|
BR9907241A
(en)
|
1998-01-26 |
2000-10-17 |
Unilever Nv |
Expression library, process for preparing the same, using an unimmunized source of nucleic acid sequences, and, processes for preparing antibody fragments and, for preparing an antibody
|
CZ121599A3
(en)
|
1998-04-09 |
1999-10-13 |
Aventis Pharma Deutschland Gmbh |
Single-chain molecule binding several antigens, process of its preparation and medicament in which the molecule is comprised
|
US6682736B1
(en)
|
1998-12-23 |
2004-01-27 |
Abgenix, Inc. |
Human monoclonal antibodies to CTLA-4
|
WO2000043507A1
(en)
|
1999-01-19 |
2000-07-27 |
Unilever Plc |
Method for producing antibody fragments
|
WO2001014557A1
(en)
|
1999-08-23 |
2001-03-01 |
Dana-Farber Cancer Institute, Inc. |
Pd-1, a receptor for b7-4, and uses therefor
|
CN1371416B
(en)
|
1999-08-24 |
2012-10-10 |
梅达里克斯公司 |
Human CTLA-4 antibodies and their uses
|
US7605238B2
(en)
|
1999-08-24 |
2009-10-20 |
Medarex, Inc. |
Human CTLA-4 antibodies and their uses
|
WO2001030381A2
(en)
|
1999-10-28 |
2001-05-03 |
Hofbauer, Reinhold |
Use of csf-1 inhibitors
|
US6326193B1
(en)
|
1999-11-05 |
2001-12-04 |
Cambria Biosciences, Llc |
Insect control agent
|
US20060228364A1
(en)
|
1999-12-24 |
2006-10-12 |
Genentech, Inc. |
Serum albumin binding peptides for tumor targeting
|
EP1261376A1
(en)
|
2000-01-27 |
2002-12-04 |
Genetics Institute, LLC |
Antibodies against ctla4(cd152), conjugates comprising same, and uses thereof
|
US6867041B2
(en)
|
2000-02-24 |
2005-03-15 |
Xcyte Therapies, Inc. |
Simultaneous stimulation and concentration of cells
|
US6797514B2
(en)
|
2000-02-24 |
2004-09-28 |
Xcyte Therapies, Inc. |
Simultaneous stimulation and concentration of cells
|
DE60130435T2
(en)
|
2000-02-24 |
2009-07-23 |
Invitrogen Corp., Carlsbad |
SIMULTANEOUS STIMULATION AND CONCENTRATION OF CELLS
|
US7572631B2
(en)
|
2000-02-24 |
2009-08-11 |
Invitrogen Corporation |
Activation and expansion of T cells
|
WO2001087977A2
(en)
|
2000-05-12 |
2001-11-22 |
Amgen Inc. |
Methods and compositions of matter concerning april/g70, bcma, blys/agp-3, and taci
|
WO2001090190A2
(en)
|
2000-05-26 |
2001-11-29 |
National Research Council Of Canada |
Single-domain antigen-binding antibody fragments derived from llama antibodies
|
WO2001096584A2
(en)
|
2000-06-12 |
2001-12-20 |
Akkadix Corporation |
Materials and methods for the control of nematodes
|
AU9263101A
(en)
|
2000-09-11 |
2002-03-26 |
Donald W Kufe |
Muc1 extracellular domain and cancer treatment compositions and methods derived therefrom
|
GB0100621D0
(en)
|
2001-01-10 |
2001-02-21 |
Vernalis Res Ltd |
Chemical compounds VI
|
CN1294148C
(en)
|
2001-04-11 |
2007-01-10 |
中国科学院遗传与发育生物学研究所 |
Single-stranded cyctic trispecific antibody
|
GB0110029D0
(en)
|
2001-04-24 |
2001-06-13 |
Grosveld Frank |
Transgenic animal
|
CN1195779C
(en)
|
2001-05-24 |
2005-04-06 |
中国科学院遗传与发育生物学研究所 |
Double-specificity antibody resisting human ovary cancer and human CD3
|
US7666414B2
(en)
|
2001-06-01 |
2010-02-23 |
Cornell Research Foundation, Inc. |
Methods for treating prostate cancer using modified antibodies to prostate-specific membrane antigen
|
CN1966525A
(en)
|
2001-06-13 |
2007-05-23 |
根马布股份公司 |
Human monoclonal antibodies to epidermal growth factor receptor (egfr)
|
US7595378B2
(en)
|
2001-06-13 |
2009-09-29 |
Genmab A/S |
Human monoclonal antibodies to epidermal growth factor receptor (EGFR)
|
EP1433793A4
(en)
|
2001-09-13 |
2006-01-25 |
Inst Antibodies Co Ltd |
Method of constructing camel antibody library
|
US20050215472A1
(en)
|
2001-10-23 |
2005-09-29 |
Psma Development Company, Llc |
PSMA formulations and uses thereof
|
EP3184539A3
(en)
|
2001-10-23 |
2017-09-13 |
PSMA Development Company L.L.C. |
Psma antibodies
|
JP2005289809A
(en)
|
2001-10-24 |
2005-10-20 |
Vlaams Interuniversitair Inst Voor Biotechnologie Vzw (Vib Vzw) |
Mutant heavy-chain antibody
|
US7745140B2
(en)
|
2002-01-03 |
2010-06-29 |
The Trustees Of The University Of Pennsylvania |
Activation and expansion of T-cells using an engineered multivalent signaling platform as a research tool
|
CA2474616A1
(en)
|
2002-01-28 |
2003-08-07 |
Medarex, Inc. |
Human monoclonal antibodies to prostate specific membrane antigen (psma)
|
US20040132101A1
(en)
|
2002-09-27 |
2004-07-08 |
Xencor |
Optimized Fc variants and methods for their generation
|
SG187991A1
(en)
|
2002-05-02 |
2013-03-28 |
Wyeth Corp |
Calicheamicin derivative-carrier conjugates
|
EP2366718A3
(en)
|
2002-06-28 |
2012-05-02 |
Domantis Limited |
Ligand
|
US9321832B2
(en)
|
2002-06-28 |
2016-04-26 |
Domantis Limited |
Ligand
|
JP2006500921A
(en)
|
2002-07-30 |
2006-01-12 |
ブリストル−マイヤーズ スクイブ カンパニー |
Humanized antibody against human 4-1BB
|
KR20090088973A
(en)
|
2002-10-17 |
2009-08-20 |
젠맵 에이/에스 |
Human monoclonal antibodies against cd20
|
ES2539627T3
(en)
|
2002-11-07 |
2015-07-02 |
Immunogen, Inc. |
Anti-CD33 antibodies and method for the treatment of acute myeloid leukemia using them
|
ES2306900T3
(en)
|
2002-11-07 |
2008-11-16 |
Erasmus Universiteit Rotterdam |
FRET PROBES AND METHODS TO DETECT INTERACTION MOLECULES.
|
ES2551682T3
(en)
|
2002-11-08 |
2015-11-23 |
Ablynx N.V. |
Single domain antibodies directed against tumor necrosis factor-alpha and uses for them
|
EP1558650A2
(en)
|
2002-11-08 |
2005-08-03 |
Ablynx N.V. |
Camelidae antibodies against immunoglobulin e and use thereof for the treatment of allergic disorders
|
JP2006519763A
(en)
|
2002-11-08 |
2006-08-31 |
アブリンクス エン.ヴェー. |
Method of administering therapeutic polypeptides and polypeptides therefor
|
US9320792B2
(en)
|
2002-11-08 |
2016-04-26 |
Ablynx N.V. |
Pulmonary administration of immunoglobulin single variable domains and constructs thereof
|
GB0228210D0
(en)
|
2002-12-03 |
2003-01-08 |
Babraham Inst |
Single chain antibodies
|
SI2289936T1
(en)
|
2002-12-16 |
2017-10-30 |
Genentech, Inc. |
Immunoglobulin variants and uses thereof
|
ES2367430T3
(en)
|
2002-12-23 |
2011-11-03 |
Wyeth Llc |
ANTIBODIES AGAINST PD-1 AND ITS USES.
|
AU2004242845B2
(en)
|
2003-05-31 |
2011-06-02 |
Amgen Research (Munich) Gmbh |
Human-anti-human CD3 binding molecules
|
AU2004255216B2
(en)
|
2003-07-01 |
2010-08-19 |
Immunomedics, Inc. |
Multivalent carriers of bi-specific antibodies
|
MXPA05013923A
(en)
|
2003-07-02 |
2006-08-11 |
Univ Genova |
Compositions and methods for regulating nk cell activity.
|
BRPI0412890B8
(en)
|
2003-07-24 |
2021-05-25 |
Innate Pharma |
method of selecting an anti-kir2dl1 antibody or antigen-binding antibody fragment
|
EP2272566A3
(en)
|
2003-08-18 |
2013-01-02 |
MedImmune, LLC |
Humanisation of antibodies
|
AU2004280333A1
(en)
|
2003-08-22 |
2005-04-21 |
Medimmune, Llc |
Humanization of antibodies
|
US7288638B2
(en)
|
2003-10-10 |
2007-10-30 |
Bristol-Myers Squibb Company |
Fully human antibodies against human 4-1BB
|
BRPI0415457A
(en)
|
2003-10-16 |
2006-12-05 |
Micromet Ag |
cytotoxically active cd3 specific binding construct, its production process, composition comprising the same, nucleic acid sequence, vector, host, its uses in the preparation of a pharmaceutical composition and kit comprising the same
|
CN100376599C
(en)
|
2004-04-01 |
2008-03-26 |
北京安波特基因工程技术有限公司 |
Recombining single chained three specific antibodies of anti CCA, anti CD 3, anti CD 28 through genetic engineering
|
EP2295588B1
(en)
|
2004-05-27 |
2018-03-07 |
The Trustees Of The University Of Pennsylvania |
Novel artificial antigen presenting cells and uses thefor
|
KR20120133403A
(en)
|
2004-06-01 |
2012-12-10 |
도만티스 리미티드 |
Bispecific fusion antibodies with enhanced serum half-life
|
EP1786918A4
(en)
|
2004-07-17 |
2009-02-11 |
Imclone Systems Inc |
Novel tetravalent bispecific antibody
|
EP1634603A1
(en)
|
2004-08-26 |
2006-03-15 |
Eberhard-Karls-Universität Tübingen Universitätsklinikum |
Treatment of transformed or infected biologic Cells
|
US20080069772A1
(en)
|
2004-08-26 |
2008-03-20 |
Eberhard-Karls-Universitaet Tuebingen Universitaetsklinikum |
Treatment of transformed or infected biological cells
|
FR2879605B1
(en)
|
2004-12-16 |
2008-10-17 |
Centre Nat Rech Scient Cnrse |
PRODUCTION OF ANTIBODY FORMATS AND IMMUNOLOGICAL APPLICATIONS OF THESE FORMATS
|
EP1752471B9
(en)
|
2005-01-05 |
2009-04-15 |
f-star Biotechnologische Forschungs- und Entwicklungsges.m.b.H. |
Synthetic immunoglobulin domains with binding properties engineered in regions of the molecule different from the complementarity determining regions
|
WO2006072625A2
(en)
|
2005-01-06 |
2006-07-13 |
Novo Nordisk A/S |
Anti-kir combination treatments and methods
|
PT1836225E
(en)
|
2005-01-06 |
2012-01-10 |
Novo Nordisk As |
Kir-binding agents and methods of use thereof
|
EP2343320B1
(en)
|
2005-03-25 |
2017-10-25 |
GITR, Inc. |
Anti-gitr antibodies and uses thereof
|
US7833979B2
(en)
|
2005-04-22 |
2010-11-16 |
Amgen Inc. |
Toxin peptide therapeutic agents
|
US20060252096A1
(en)
|
2005-04-26 |
2006-11-09 |
Glycofi, Inc. |
Single chain antibody with cleavable linker
|
ES2427646T5
(en)
|
2005-05-09 |
2017-08-22 |
Ono Pharmaceutical Co., Ltd. |
Human monoclonal antibodies against programmed death 1 (PD1) and methods for the treatment of cancer through the use of anti-PD-1 antibodies alone or in combination with other immunotherapeutic agents
|
EP1888640B1
(en)
|
2005-05-18 |
2012-03-14 |
Ablynx N.V. |
Improved nanobodies against tumor necrosis factor-alpha
|
MX2007014564A
(en)
|
2005-05-20 |
2008-02-07 |
Ablynx Nv |
Single domain vhh antibodies against von willebrand factor.
|
EP1726650A1
(en)
|
2005-05-27 |
2006-11-29 |
Universitätsklinikum Freiburg |
Monoclonal antibodies and single chain antibody fragments against cell-surface prostate specific membrane antigen
|
MX2007015942A
(en)
|
2005-07-01 |
2008-03-07 |
Medarex Inc |
Human monoclonal antibodies to programmed death ligand 1 (pd-l1).
|
BRPI0615026A8
(en)
|
2005-08-19 |
2018-03-06 |
Abbott Lab |
double variable domain immunoglobulin and its uses
|
AU2006301492B2
(en)
|
2005-10-11 |
2011-06-09 |
Amgen Research (Munich) Gmbh |
Compositions comprising cross-species-specific antibodies and uses thereof
|
EP1934260B1
(en)
|
2005-10-14 |
2017-05-17 |
Innate Pharma |
Compositions and methods for treating proliferative disorders
|
GB0521991D0
(en)
|
2005-10-28 |
2005-12-07 |
Univ Dundee |
Siglec-9 binding agents
|
ES2340205T3
(en)
|
2005-11-12 |
2010-05-31 |
Eli Lilly And Company |
ANTI-EGFR ANTIBODIES.
|
WO2007062466A1
(en)
|
2005-11-29 |
2007-06-07 |
The University Of Sydney |
Demibodies: dimerisation-activated therapeutic agents
|
US7498142B2
(en)
|
2006-01-31 |
2009-03-03 |
Yeda Research And Development Co., Ltd. |
Methods of identifying combinations of antibodies with an improved anti-tumor activity and compositions and methods using the antibodies
|
WO2007115230A2
(en)
|
2006-03-30 |
2007-10-11 |
University Of Medicine And Dentistry Of New Jersey |
A strategy for homo- or hetero-dimerization of various proteins in solutions and in cells
|
EP2007423A2
(en)
|
2006-04-05 |
2008-12-31 |
Pfizer Products Incorporated |
Ctla4 antibody combination therapy
|
US20070269422A1
(en)
|
2006-05-17 |
2007-11-22 |
Ablynx N.V. |
Serum albumin binding proteins with long half-lives
|
AU2007285695B2
(en)
|
2006-08-18 |
2012-05-24 |
Ablynx N.V. |
Amino acid sequences directed against IL-6R and polypeptides comprising the same for the treatment of diseases and disorders associated with IL-6-mediated signalling
|
AU2007293614A1
(en)
|
2006-09-08 |
2008-03-13 |
Ablynx N.V. |
Serum albumin binding proteins with long half-lives
|
US20100166734A1
(en)
|
2006-12-20 |
2010-07-01 |
Edward Dolk |
Oral delivery of polypeptides
|
ES2579768T3
(en)
|
2007-01-11 |
2016-08-16 |
Novo Nordisk A/S |
Anti-KIR antibodies, formulations and uses thereof
|
AU2008234020B2
(en)
|
2007-04-03 |
2013-02-07 |
Amgen Research (Munich) Gmbh |
Cross-species-specific CD3-epsilon binding domain
|
JP2008278814A
(en)
|
2007-05-11 |
2008-11-20 |
Igaku Seibutsugaku Kenkyusho:Kk |
Release of immunoregulation by agonistic anti-human gitr antibody, and application thereof
|
KR20120125601A
(en)
|
2007-05-24 |
2012-11-16 |
아블린쓰 엔.브이. |
Amino acid sequences directed against rank-l and polypeptides comprising the same for the treatment of bone diseases and disorders
|
RS53072B
(en)
|
2007-06-18 |
2014-04-30 |
Merck Sharp & Dohme B.V. |
Antibodies to human programmed death receptor pd-1
|
EP2014680A1
(en)
|
2007-07-10 |
2009-01-14 |
Friedrich-Alexander-Universität Erlangen-Nürnberg |
Recombinant, single-chain, trivalent tri-specific or bi-specific antibody derivatives
|
JP5932217B2
(en)
|
2007-07-12 |
2016-06-08 |
ジーアイティーアール, インコーポレイテッド |
Combination therapy using GITR binding molecules
|
EP2487190A3
(en)
|
2007-07-13 |
2012-11-14 |
Bac Ip B.V. |
Single-domain antigen-binding proteins that bind mammalian IgG
|
CA2697032C
(en)
|
2007-08-22 |
2021-09-14 |
The Regents Of The University Of California |
Activatable binding polypeptides and methods of identification and use thereof
|
CA2698419C
(en)
|
2007-09-07 |
2019-11-12 |
Edward Dolk |
Binding molecules with multiple binding sites, compositions comprising the same and uses thereof
|
US7982016B2
(en)
|
2007-09-10 |
2011-07-19 |
Amgen Inc. |
Antigen binding proteins capable of binding thymic stromal lymphopoietin
|
US8629246B2
(en)
|
2007-09-26 |
2014-01-14 |
Ucb Pharma S.A. |
Dual specificity antibody fusions
|
CA2712220A1
(en)
|
2008-01-24 |
2009-07-30 |
Novo Nordisk A/S |
Humanized anti-human nkg2a monoclonal antibody
|
PT2242773T
(en)
|
2008-02-11 |
2017-09-15 |
Cure Tech Ltd |
Monoclonal antibodies for tumor treatment
|
EP2262837A4
(en)
|
2008-03-12 |
2011-04-06 |
Merck Sharp & Dohme |
Pd-1 binding proteins
|
SI2285408T1
(en)
|
2008-06-05 |
2019-02-28 |
Ablynx N.V. |
Amino acid sequences directed against envelope proteins of a virus and polypeptides comprising the same for the treatment of viral diseases
|
US20100122358A1
(en)
|
2008-06-06 |
2010-05-13 |
Crescendo Biologics Limited |
H-Chain-only antibodies
|
US8444976B2
(en)
|
2008-07-02 |
2013-05-21 |
Argen-X B.V. |
Antigen binding polypeptides
|
WO2010003118A1
(en)
|
2008-07-02 |
2010-01-07 |
Trubion Pharmaceuticals, Inc. |
Tgf-b antagonist multi-target binding proteins
|
DE102008036127A1
(en)
|
2008-08-01 |
2010-02-04 |
Emitec Gesellschaft Für Emissionstechnologie Mbh |
Method for operating an exhaust system with lambda control
|
AR072999A1
(en)
|
2008-08-11 |
2010-10-06 |
Medarex Inc |
HUMAN ANTIBODIES THAT JOIN GEN 3 OF LYMPHOCYTARY ACTIVATION (LAG-3) AND THE USES OF THESE
|
WO2010027423A2
(en)
|
2008-08-25 |
2010-03-11 |
Amplimmune, Inc. |
Compositions of pd-1 antagonists and methods of use
|
EP2328919A2
(en)
|
2008-08-25 |
2011-06-08 |
Amplimmune, Inc. |
Pd-i antagonists and methods for treating infectious disease
|
DK2352763T4
(en)
|
2008-10-01 |
2022-10-17 |
Amgen Res Munich Gmbh |
BISPECIFIC SINGLE CHAIN ANTIBODIES WITH SPECIFICITY FOR HIGH MOLECULAR TARGET ANTIGENS
|
PT2356153T
(en)
|
2008-10-01 |
2016-07-15 |
Amgen Res (Munich) Gmbh |
Cross-species-specific psmaxcd3 bispecific single chain antibody
|
EP2352765B1
(en)
|
2008-10-01 |
2018-01-03 |
Amgen Research (Munich) GmbH |
Cross-species-specific single domain bispecific single chain antibody
|
WO2010043057A1
(en)
|
2008-10-14 |
2010-04-22 |
National Research Counsil Of Canada |
Bsa-specific antibodies
|
US8709411B2
(en)
|
2008-12-05 |
2014-04-29 |
Novo Nordisk A/S |
Combination therapy to enhance NK cell mediated cytotoxicity
|
JP2012511033A
(en)
|
2008-12-08 |
2012-05-17 |
テゴファーム コーポレーション |
Masking ligand for reversible inhibition of multivalent compounds
|
HUE034832T2
(en)
|
2008-12-09 |
2021-12-28 |
Hoffmann La Roche |
Anti-pd-l1 antibodies and their use to enhance t-cell function
|
US9345787B2
(en)
|
2008-12-22 |
2016-05-24 |
Targovax Oy |
Adenoviral vectors and methods and uses related thereto
|
EP2385955B1
(en)
|
2009-01-12 |
2020-08-12 |
CytomX Therapeutics, Inc. |
Modified antibody compositions, methods of making and using thereof
|
EP2210902A1
(en)
|
2009-01-14 |
2010-07-28 |
TcL Pharma |
Recombinant monovalent antibodies
|
US8741295B2
(en)
|
2009-02-09 |
2014-06-03 |
Universite De La Mediterranee |
PD-1 antibodies and PD-L1 antibodies and uses thereof
|
AR075798A1
(en)
|
2009-03-05 |
2011-04-27 |
Abbott Lab |
PROTEINS OF UNION TO IL-17 (INTERLEUQUINA 17)
|
EP2473531A4
(en)
|
2009-09-03 |
2013-05-01 |
Merck Sharp & Dohme |
Anti-gitr antibodies
|
US20110195494A1
(en)
|
2009-10-02 |
2011-08-11 |
Boehringer Ingelheim International Gmbh |
Dll4-binging molecules
|
WO2011051327A2
(en)
|
2009-10-30 |
2011-05-05 |
Novartis Ag |
Small antibody-like single chain proteins
|
US20130017199A1
(en)
|
2009-11-24 |
2013-01-17 |
AMPLIMMUNE ,Inc. a corporation |
Simultaneous inhibition of pd-l1/pd-l2
|
CA2781682A1
(en)
|
2009-12-04 |
2011-06-09 |
Genentech, Inc. |
Multispecific antibodies, antibody analogs, compositions, and methods
|
EP2332994A1
(en)
|
2009-12-09 |
2011-06-15 |
Friedrich-Alexander-Universität Erlangen-Nürnberg |
Trispecific therapeutics against acute myeloid leukaemia
|
BR112012013717B1
(en)
|
2009-12-10 |
2020-01-28 |
Hoffmann La Roche |
antibodies binding to human csf-1r, pharmaceutical composition and uses of the antibody
|
AU2010343057B2
(en)
|
2009-12-29 |
2017-02-23 |
Aptevo Research And Development Llc |
Heterodimer binding proteins and uses thereof
|
GB2476681B
(en)
|
2010-01-04 |
2012-04-04 |
Argen X Bv |
Humanized camelid VH, VK and VL immunoglobulin domains
|
SI2530091T1
(en)
|
2010-01-29 |
2018-06-29 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-dll3 antibody
|
KR101647871B1
(en)
|
2010-03-05 |
2016-08-11 |
에프. 호프만-라 로슈 아게 |
Antibodies against human csf-1r and uses thereof
|
KR101656548B1
(en)
|
2010-03-05 |
2016-09-09 |
에프. 호프만-라 로슈 아게 |
Antibodies against human csf-1r and uses thereof
|
EP2550529B1
(en)
|
2010-03-23 |
2021-11-17 |
Iogenetics, LLC. |
Bioinformatic processes for determination of peptide binding
|
US8937164B2
(en)
|
2010-03-26 |
2015-01-20 |
Ablynx N.V. |
Biological materials related to CXCR7
|
US9556273B2
(en)
|
2010-03-29 |
2017-01-31 |
Vib Vzw |
Anti-macrophage mannose receptor single variable domains for targeting and in vivo imaging of tumor-associated macrophages
|
ES2706412T3
(en)
|
2010-05-04 |
2019-03-28 |
Five Prime Therapeutics Inc |
Antibodies that bind to CSF1R
|
EP3363499A1
(en)
|
2010-06-11 |
2018-08-22 |
Kyowa Hakko Kirin Co., Ltd. |
Anti-tim-3 antibody
|
DK3336225T3
(en)
|
2010-07-16 |
2020-03-30 |
Adimab Llc |
ANTIBODY LIBRARIES
|
US8900590B2
(en)
|
2010-08-12 |
2014-12-02 |
Theraclone Sciences, Inc. |
Anti-hemagglutinin antibody compositions and methods of use thereof
|
BR112013002167A2
(en)
|
2010-08-24 |
2016-05-31 |
Roche Glycart Ag |
bispecific antibody, pharmaceutical composition, use, method of treatment of a cancer patient and a patient suffering from inflammation
|
WO2012025530A1
(en)
|
2010-08-24 |
2012-03-01 |
F. Hoffmann-La Roche Ag |
Bispecific antibodies comprising a disulfide stabilized - fv fragment
|
EP2621953B1
(en)
|
2010-09-30 |
2017-04-05 |
Ablynx N.V. |
Biological materials related to c-met
|
EP2640750A1
(en)
|
2010-11-16 |
2013-09-25 |
Boehringer Ingelheim International GmbH |
Agents and methods for treating diseases that correlate with bcma expression
|
JP6224457B2
(en)
|
2010-11-22 |
2017-11-01 |
イネイト・ファルマ・ソシエテ・アノニム |
NK cell regulatory treatment and malignant blood disease treatment method
|
CA2828940C
(en)
|
2011-03-10 |
2024-04-16 |
Provectus Pharmaceuticals, Inc. |
Combination of local and systemic immunomodulative therapies for enhanced treatment of cancer
|
US9029113B2
(en)
|
2011-03-11 |
2015-05-12 |
Kaneka Corporation |
Modified aminotransferase, gene thereof, and method for producing optically active amino compound using same
|
WO2012131053A1
(en)
|
2011-03-30 |
2012-10-04 |
Ablynx Nv |
Methods of treating immune disorders with single domain antibodies against tnf-alpha
|
JP6076963B2
(en)
|
2011-04-08 |
2017-02-15 |
アメリカ合衆国 |
Anti-epidermal growth factor receptor variant III chimeric antigen receptor and its use for the treatment of cancer
|
MX338353B
(en)
|
2011-04-20 |
2016-04-13 |
Medimmune Llc |
Antibodies and other molecules that bind b7-h1 and pd-1.
|
US8846042B2
(en)
|
2011-05-16 |
2014-09-30 |
Fabion Pharmaceuticals, Inc. |
Multi-specific FAB fusion proteins and methods of use
|
CA2837184C
(en)
|
2011-05-25 |
2021-09-21 |
Innate Pharma, S.A. |
Anti-kir antibodies for the treatment of inflammatory and autoimmune disorders
|
KR101972446B1
(en)
|
2011-05-27 |
2019-04-25 |
글락소 그룹 리미티드 |
Bcma(cd269/tnfrsf17)-binding proteins
|
AU2012271974B2
(en)
|
2011-06-23 |
2017-01-12 |
Ablynx Nv |
Serum albumin binding proteins
|
WO2013006490A2
(en)
|
2011-07-01 |
2013-01-10 |
Cellerant Therapeutics, Inc. |
Antibodies that specifically bind to tim3
|
UA117901C2
(en)
|
2011-07-06 |
2018-10-25 |
Ґенмаб Б.В. |
Antibody variants and uses thereof
|
EP2753644A1
(en)
|
2011-09-09 |
2014-07-16 |
Universiteit Utrecht Holding B.V. |
Broadly neutralizing vhh against hiv-1
|
WO2013039954A1
(en)
|
2011-09-14 |
2013-03-21 |
Sanofi |
Anti-gitr antibodies
|
WO2013041730A1
(en)
|
2011-09-23 |
2013-03-28 |
Universität Stuttgart Please note that the status of the person identified in Box 1 changed from Applicant for all designated States except US to Applicant for all designated States. |
Serum half-life extension using immunoglobulin binding domains
|
JP6219287B2
(en)
|
2011-09-30 |
2017-10-25 |
アブリンクス エン.ヴェー. |
Biological substances related to c-Met
|
TWI679212B
(en)
|
2011-11-15 |
2019-12-11 |
美商安進股份有限公司 |
Binding molecules for e3 of bcma and cd3
|
JP6138813B2
(en)
|
2011-11-28 |
2017-05-31 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングMerck Patent Gesellschaft mit beschraenkter Haftung |
Anti-PD-L1 antibody and use thereof
|
WO2013087699A1
(en)
|
2011-12-15 |
2013-06-20 |
F. Hoffmann-La Roche Ag |
Antibodies against human csf-1r and uses thereof
|
WO2013088304A1
(en)
|
2011-12-16 |
2013-06-20 |
Pfizer Inc. |
Combination of inotuzumab ozogamicin and torisel for the treatment of cancer
|
EP2793918B1
(en)
|
2011-12-19 |
2019-09-11 |
The Rockefeller University |
Hdc-sign binding peptides
|
EA033947B1
(en)
|
2012-01-13 |
2019-12-12 |
Юлиус-Максимилианс-Универзитет Вюрцбург |
Set of polypeptides for identifying and/or eliminating cells, use thereof, nucleic acid molecule encoding one of the polypeptides of the set, set of nucleic acids encoding the set of polypeptides, pharmaceutical composition comprising these sets
|
EP2807189B1
(en)
|
2012-01-23 |
2019-03-20 |
Ablynx N.V. |
Sequences directed against hepatocyte growth factor (hgf) and polypeptides comprising the same for the treatment of cancers and/or tumors
|
CA2861122A1
(en)
|
2012-02-06 |
2013-08-15 |
Genentech, Inc. |
Compositions and methods for using csf1r inhibitors
|
WO2013126712A1
(en)
|
2012-02-22 |
2013-08-29 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for generating a persisting population of t cells useful for the treatment of cancer
|
PE20190658A1
(en)
|
2012-02-24 |
2019-05-08 |
Abbvie Stemcentrx Llc |
NEW MODULATORS AND EMPLOYMENT METHODS
|
GB201203442D0
(en)
|
2012-02-28 |
2012-04-11 |
Univ Birmingham |
Immunotherapeutic molecules and uses
|
EP2820047B1
(en)
|
2012-03-01 |
2018-04-25 |
Amgen Research (Munich) GmbH |
Long life polypeptide binding molecules
|
AR090263A1
(en)
|
2012-03-08 |
2014-10-29 |
Hoffmann La Roche |
COMBINED ANTIBODY THERAPY AGAINST HUMAN CSF-1R AND USES OF THE SAME
|
KR20150030639A
(en)
|
2012-03-30 |
2015-03-20 |
바이엘 헬스케어 엘엘씨 |
Protease-regulated antibodies
|
BR112014025830A8
(en)
|
2012-04-20 |
2017-10-10 |
Emergent Product Dev Seattle |
CD3-BINDING POLYPEPTIDES
|
BR112014028013A2
(en)
|
2012-05-11 |
2018-02-27 |
Five Prime Therapeutics Inc |
methods for treating a condition associated with rheumatoid arthritis, rheumatoid arthritis, skin lesions, lupus nephritis, lupus, an inflammatory condition, cd16 + disorder, method for reducing the number of cd16 + monocytes, methods for slowing the progression of a renal condition, rag and bone loss
|
EP2850102A1
(en)
|
2012-05-15 |
2015-03-25 |
Bristol-Myers Squibb Company |
Cancer immunotherapy by disrupting pd-1/pd-l1 signaling
|
KR101566538B1
(en)
|
2012-06-08 |
2015-11-05 |
국립암센터 |
Novel epitope for switching to Th17 cell and use thereof
|
US9856314B2
(en)
|
2012-06-22 |
2018-01-02 |
Cytomx Therapeutics, Inc. |
Activatable antibodies having non-binding steric moieties and methods of using the same
|
WO2014004549A2
(en)
|
2012-06-27 |
2014-01-03 |
Amgen Inc. |
Anti-mesothelin binding proteins
|
UY34887A
(en)
|
2012-07-02 |
2013-12-31 |
Bristol Myers Squibb Company Una Corporacion Del Estado De Delaware |
OPTIMIZATION OF ANTIBODIES THAT FIX THE LYMPHOCYTE ACTIVATION GEN 3 (LAG-3) AND ITS USES
|
US20140154253A1
(en)
|
2012-07-13 |
2014-06-05 |
Zymeworks Inc. |
Bispecific Asymmetric Heterodimers Comprising Anti-CD3 Constructs
|
CN112587671A
(en)
|
2012-07-18 |
2021-04-02 |
博笛生物科技有限公司 |
Targeted immunotherapy for cancer
|
US10040870B2
(en)
|
2012-08-31 |
2018-08-07 |
Argenx Bvba |
Highly diverse combinatorial antibody libraries
|
CA2882804A1
(en)
|
2012-08-31 |
2014-03-06 |
Brian Wong |
Methods of treating conditions with antibodies that bind colony stimulating factor 1 receptor (csf1r)
|
KR101963231B1
(en)
|
2012-09-11 |
2019-03-28 |
삼성전자주식회사 |
Protein complex for preparing bispecific antibodies and method using thereof
|
JOP20200236A1
(en)
|
2012-09-21 |
2017-06-16 |
Regeneron Pharma |
Anti-cd3 antibodies, bispecific antigen-binding molecules that bind cd3 and cd20, and uses thereof
|
EP2900695B1
(en)
|
2012-09-27 |
2018-01-17 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Mesothelin antibodies and methods for eliciting potent antitumor activity
|
ES2643887T3
(en)
|
2012-10-02 |
2017-11-27 |
Bristol-Myers Squibb Company |
Combination of anti-KIR antibodies and anti-PD-1 antibodies to treat cancer
|
US9243058B2
(en)
*
|
2012-12-07 |
2016-01-26 |
Amgen, Inc. |
BCMA antigen binding proteins
|
PT3575326T
(en)
|
2012-12-17 |
2022-05-30 |
Pf Argentum Ip Holdings Llc |
Treatment of cd47+ disease cells with sirp alpha-fc fusions
|
JO3519B1
(en)
|
2013-01-25 |
2020-07-05 |
Amgen Inc |
Antibody constructs for CDH19 and CD3
|
GB201302447D0
(en)
|
2013-02-12 |
2013-03-27 |
Oxford Biotherapeutics Ltd |
Therapeutic and diagnostic target
|
JP6462591B2
(en)
|
2013-02-22 |
2019-01-30 |
アッヴィ・ステムセントルクス・エル・エル・シー |
Novel antibody conjugates and uses thereof
|
MX2015011199A
(en)
|
2013-02-28 |
2015-12-16 |
Univ Edinburgh |
Csf1 therapeutics.
|
US20160015749A1
(en)
|
2013-03-05 |
2016-01-21 |
Baylor College Of Medicine |
Engager cells for immunotherapy
|
EP3404111A1
(en)
|
2013-03-13 |
2018-11-21 |
Health Research, Inc. |
Compositions and methods for use of recombinant t cell receptors for direct recognition of tumor antigen
|
CN110420333A
(en)
|
2013-03-14 |
2019-11-08 |
斯克利普斯研究所 |
Targeting agent antibody coupling matter and application thereof
|
US9725520B2
(en)
|
2013-03-14 |
2017-08-08 |
The Board Of Regents Of The University Of Texas System |
HER3 specific monoclonal antibodies for diagnostic and therapeutic use
|
US20160009817A1
(en)
|
2013-03-15 |
2016-01-14 |
Bayer Healthcare Llc |
Pro-drug antibodies against tissue factor pathway inhibitor
|
SI2970449T1
(en)
|
2013-03-15 |
2019-11-29 |
Amgen Res Munich Gmbh |
Single chain binding molecules comprising n-terminal abp
|
US20140302037A1
(en)
|
2013-03-15 |
2014-10-09 |
Amgen Inc. |
BISPECIFIC-Fc MOLECULES
|
EP2970484B2
(en)
|
2013-03-15 |
2022-09-21 |
Amgen Inc. |
Heterodimeric bispecific antibodies
|
UY35468A
(en)
|
2013-03-16 |
2014-10-31 |
Novartis Ag |
CANCER TREATMENT USING AN ANTI-CD19 CHEMERIC ANTIGEN RECEIVER
|
CN105377297B
(en)
|
2013-05-28 |
2019-09-17 |
Dcb-美国有限责任公司 |
Antibody lock for pharmaceutical grade protein inactivation
|
ES2683268T3
(en)
|
2013-07-25 |
2018-09-25 |
Cytomx Therapeutics, Inc. |
Multispecific antibodies, multispecific activatable antibodies and methods for using them
|
MX2016001356A
(en)
|
2013-08-01 |
2016-10-26 |
Ludwig Inst For Cancer Res Ltd |
Anti-garp protein and uses thereof.
|
AR097306A1
(en)
|
2013-08-20 |
2016-03-02 |
Merck Sharp & Dohme |
MODULATION OF TUMOR IMMUNITY
|
CN105873612A
(en)
|
2013-08-28 |
2016-08-17 |
施特姆森特克斯股份有限公司 |
Engineered anti-DLL3 conjugates and methods of use
|
TW201605896A
(en)
|
2013-08-30 |
2016-02-16 |
安美基股份有限公司 |
GITR antigen binding proteins
|
JP6623353B2
(en)
|
2013-09-13 |
2019-12-25 |
ベイジーン スウィッツァーランド ゲーエムベーハー |
Anti-PD-1 antibodies and their use for therapy and diagnosis
|
RS64268B1
(en)
|
2013-09-20 |
2023-07-31 |
Bristol Myers Squibb Co |
Combination of anti-lag-3 antibodies and anti-pd-1 antibodies to treat tumors
|
WO2015048081A1
(en)
|
2013-09-24 |
2015-04-02 |
Andre Lieber |
Desmoglein 2 (dsg2) binding proteins and uses therefor
|
EP3049439B1
(en)
|
2013-09-26 |
2019-12-25 |
Ablynx N.V. |
Bispecific nanobodies
|
US20160263087A1
(en)
|
2013-11-08 |
2016-09-15 |
Iteos Therapeutics |
Novel 4-(indol-3-yl)-pyrazole derivatives, pharmaceutical compositions and methods for use
|
US9126984B2
(en)
|
2013-11-08 |
2015-09-08 |
Iteos Therapeutics |
4-(indol-3-yl)-pyrazole derivatives, pharmaceutical compositions and methods for use
|
WO2015082499A2
(en)
|
2013-12-03 |
2015-06-11 |
Iomet Pharma Ltd |
Pharmaceutical compound
|
BR112016015140A2
(en)
|
2013-12-30 |
2018-01-23 |
Epimab Biotherapeutics Inc. |
tandem-fab immunoglobulin and its uses
|
CA2939164A1
(en)
|
2014-02-12 |
2015-08-20 |
Iteos Therapeutics |
Novel 3-(indol-3-yl)-pyridine derivatives, pharmaceutical compositions and methods for use
|
US10308721B2
(en)
|
2014-02-21 |
2019-06-04 |
Abbvie Stemcentrx Llc |
Anti-DLL3 antibodies and drug conjugates for use in melanoma
|
ES2939760T3
(en)
|
2014-03-15 |
2023-04-26 |
Novartis Ag |
Cancer treatment using a chimeric receptor for antigens
|
WO2015140717A1
(en)
|
2014-03-18 |
2015-09-24 |
Iteos Therapeutics |
Novel 3-indol substituted derivatives, pharmaceutical compositions and methods for use
|
CA2943167A1
(en)
|
2014-03-24 |
2015-10-01 |
University Of Southampton |
Modified antibodies containing modified igg2 domains which elicit agonist or antagonistic properties and use thereof
|
WO2015146437A1
(en)
|
2014-03-25 |
2015-10-01 |
国立大学法人東北大学 |
HIGHLY-FUNCTIONAL IgG2 BISPECIFIC ANTIBODY
|
UA117289C2
(en)
|
2014-04-02 |
2018-07-10 |
Ф. Хоффманн-Ля Рош Аг |
Multispecific antibodies
|
US10167257B2
(en)
|
2014-04-04 |
2019-01-01 |
Iomet Pharma Ltd. |
Indole derivatives for use in medicine
|
SG11201607070VA
(en)
|
2014-05-02 |
2016-11-29 |
Momenta Pharmaceuticals Inc |
Compositions and methods related to engineered fc constructs
|
MD20160118A2
(en)
|
2014-05-15 |
2017-04-30 |
Iteos Therapeutics |
Pyrrolidine-2,5-dione derivatives, pharmaceutical compositions and methods for use as IDO1 inhibitors
|
PT3148579T
(en)
|
2014-05-28 |
2021-03-11 |
Ludwig Inst For Cancer Res Ltd |
Anti-gitr antibodies and methods of use thereof
|
SG10201913324PA
(en)
|
2014-05-29 |
2020-03-30 |
Macrogenics Inc |
Tri-specific binding molecules and methods of use thereof
|
DK3151921T3
(en)
|
2014-06-06 |
2019-12-02 |
Bristol Myers Squibb Co |
ANTIBODIES AGAINST GLUCOCORTICOID-INDUCED TUMOR CANCER FACTOR RECEPTORS (GITR) AND APPLICATIONS THEREOF
|
GB201412659D0
(en)
|
2014-07-16 |
2014-08-27 |
Ucb Biopharma Sprl |
Molecules
|
RU2751660C2
(en)
|
2014-07-21 |
2021-07-15 |
Новартис Аг |
Treatment of malignant neoplasm using humanized chimeric antigen receptor against bcma
|
EP3172235A2
(en)
|
2014-07-25 |
2017-05-31 |
Cytomx Therapeutics Inc. |
Anti-cd3 antibodies, activatable anti-cd3 antibodies, multispecific anti-cd3 antibodies, multispecific activatable anti-cd3 antibodies, and methods of using the same
|
UY36245A
(en)
|
2014-07-31 |
2016-01-29 |
Amgen Res Munich Gmbh |
ANTIBODY CONSTRUCTS FOR CDH19 AND CD3
|
AU2015295242B2
(en)
|
2014-07-31 |
2020-10-22 |
Amgen Research (Munich) Gmbh |
Bispecific single chain antibody construct with enhanced tissue distribution
|
GB201414730D0
(en)
|
2014-08-19 |
2014-10-01 |
Tpp Global Dev Ltd |
Pharmaceutical compound
|
SG11201701385WA
(en)
|
2014-08-28 |
2017-03-30 |
Academisch Ziekenhuis Leiden |
Cd94/nkg2a and/or cd94/nkg2b antibody, vaccine combinations
|
MA53145A
(en)
|
2014-09-05 |
2021-05-19 |
Janssen Pharmaceutica Nv |
CD123 LIAISON AGENTS AND THEIR USES
|
CN109842529B
(en)
|
2014-09-05 |
2021-10-26 |
华为技术有限公司 |
Method, device and network system for configuring service
|
AU2015314316B2
(en)
|
2014-09-10 |
2020-12-10 |
Innate Pharma |
Cross reactive Siglec antibodies
|
EP3193929B1
(en)
|
2014-09-16 |
2019-06-12 |
Innate Pharma |
Treatment regimens using anti-nkg2a antibodies
|
AU2015323313B2
(en)
|
2014-09-25 |
2021-04-01 |
Amgen Inc. |
Protease-activatable bispecific proteins
|
MX2017004603A
(en)
|
2014-10-07 |
2017-06-30 |
Cellectis |
Method for modulating car-induced immune cells activity.
|
CA2965741C
(en)
|
2014-11-03 |
2022-05-17 |
Iomet Pharma Ltd |
Pharmaceutical compound
|
GB201419579D0
(en)
|
2014-11-03 |
2014-12-17 |
Iomet Pharma Ltd |
Pharmaceutical compound
|
JP6755866B2
(en)
|
2014-11-10 |
2020-09-16 |
メディミューン リミテッド |
CD73-specific binding molecule and its use
|
MA41019A
(en)
|
2014-11-26 |
2021-05-05 |
Xencor Inc |
HETERODIMERIC ANTIBODIES BINDING TO CD3 AND CD38 ANTIGENS
|
EP3029068A1
(en)
|
2014-12-03 |
2016-06-08 |
EngMab AG |
Bispecific antibodies against CD3epsilon and BCMA for use in the treatment of diseases
|
US11001625B2
(en)
|
2014-12-10 |
2021-05-11 |
Tufts University |
VHH based binding antibodies for anthrax and botulinum toxins and methods of making and using therefor
|
EP3237449A2
(en)
|
2014-12-22 |
2017-11-01 |
Xencor, Inc. |
Trispecific antibodies
|
WO2016125017A1
(en)
|
2015-02-03 |
2016-08-11 |
Universite Catholique De Louvain |
Anti-garp protein and uses thereof
|
MX2017010009A
(en)
|
2015-02-05 |
2017-10-24 |
Janssen Vaccines & Prevention Bv |
Binding molecules directed against influenza hemagglutinin and uses thereof.
|
EP3256495A4
(en)
|
2015-02-11 |
2018-09-19 |
Aptevo Research and Development LLC |
Compositions and methods for combination therapy with prostate-specific membrane antigen binding proteins
|
DK3259597T3
(en)
|
2015-02-19 |
2022-05-09 |
Compugen Ltd |
PVRIG POLYPEPTIDES AND METHODS OF TREATMENT
|
WO2016134333A1
(en)
|
2015-02-19 |
2016-08-25 |
Compugen Ltd. |
Anti-pvrig antibodies and methods of use
|
MA41613A
(en)
|
2015-02-23 |
2018-01-02 |
Abbvie Stemcentrx Llc |
ANTI-DLL3 CHEMERICAL ANTIGENIC RECEPTORS AND METHODS FOR USING SUCH RECEIVERS
|
US9873690B2
(en)
|
2015-03-17 |
2018-01-23 |
Pfizer Inc |
3-indol substituted derivatives, pharmaceutical compositions and methods for use
|
UA126058C2
(en)
|
2015-04-22 |
2022-08-10 |
Аґбайомі, Інк. |
Insecticidal genes and methods of use
|
EP3288981A1
(en)
|
2015-05-01 |
2018-03-07 |
Genentech, Inc. |
Masked anti-cd3 antibodies and methods of use
|
AU2016258115A1
(en)
|
2015-05-06 |
2017-11-23 |
Janssen Biotech, Inc. |
Prostate specific membrane antigen (PSMA) bispecific binding agents and uses thereof
|
WO2016182064A1
(en)
|
2015-05-13 |
2016-11-17 |
中外製薬株式会社 |
Multiple antigen binding molecular fusion, pharmaceutical composition, method for identifying linear epitope, and method for preparing multiple antigen binding molecular fusion
|
AU2016260909B2
(en)
|
2015-05-13 |
2019-08-22 |
Ablynx N.V. |
T cell recruiting polypeptides based on CD3 reactivity
|
US10945994B2
(en)
|
2015-05-14 |
2021-03-16 |
Pfizer Inc. |
Combinations comprising a pyrrolidine-2,5-dione IDO1 inhibitor and an anti-body
|
EP3297672B1
(en)
*
|
2015-05-21 |
2021-09-01 |
Harpoon Therapeutics, Inc. |
Trispecific binding proteins and methods of use
|
US10526597B2
(en)
|
2015-05-21 |
2020-01-07 |
Full Spectrum Genetics, Inc. |
Method of improving characteristics of proteins
|
US10364439B2
(en)
|
2015-06-03 |
2019-07-30 |
AgBiome, Inc. |
Pesticidal genes and methods of use
|
WO2016210447A1
(en)
|
2015-06-26 |
2016-12-29 |
University Of Southern California |
Masking chimeric antigen receptor t cells for tumor-specific activation
|
GB201511790D0
(en)
|
2015-07-06 |
2015-08-19 |
Iomet Pharma Ltd |
Pharmaceutical compound
|
LT3115376T
(en)
|
2015-07-10 |
2018-11-12 |
Merus N.V. |
Human cd3 binding antibody
|
TW202346349A
(en)
|
2015-07-31 |
2023-12-01 |
德商安美基研究(慕尼黑)公司 |
Antibody constructs for dll3 and cd3
|
TWI796283B
(en)
|
2015-07-31 |
2023-03-21 |
德商安美基研究(慕尼黑)公司 |
Antibody constructs for msln and cd3
|
TWI829617B
(en)
|
2015-07-31 |
2024-01-21 |
德商安美基研究(慕尼黑)公司 |
Antibody constructs for flt3 and cd3
|
PL3331910T3
(en)
*
|
2015-08-03 |
2020-05-18 |
Engmab Sàrl |
Monoclonal antibodies against human b cell maturation antigen (bcma)
|
WO2017027392A1
(en)
|
2015-08-07 |
2017-02-16 |
Novartis Ag |
Treatment of cancer using chimeric cd3 receptor proteins
|
CA2994917A1
(en)
|
2015-08-10 |
2017-02-16 |
Pfizer Inc. |
3-indol substituted derivatives, pharmaceutical compositions and methods for use
|
CN105384825B
(en)
*
|
2015-08-11 |
2018-06-01 |
南京传奇生物科技有限公司 |
A kind of bispecific chimeric antigen receptor and its application based on single domain antibody
|
WO2017025698A1
(en)
|
2015-08-11 |
2017-02-16 |
Queen Mary University Of London |
Bispecific, cleavable antibodies
|
CA2995754A1
(en)
|
2015-08-17 |
2017-02-23 |
Janssen Pharmaceutica Nv |
Anti-bcma antibodies, bispecific antigen binding molecules that bind bcma and cd3, and uses thereof
|
US20180243435A1
(en)
|
2015-08-20 |
2018-08-30 |
Abbvie Stemcentrx Llc |
Anti-dll3 antibody drug conjugates and methods of use
|
CN106519037B
(en)
|
2015-09-11 |
2019-07-23 |
科济生物医药(上海)有限公司 |
Activable Chimerical receptor
|
TWI836305B
(en)
|
2015-09-24 |
2024-03-21 |
日商第一三共股份有限公司 |
Anti-garp antibody and producing method and use thereof
|
SG11201803567XA
(en)
|
2015-10-29 |
2018-05-30 |
Alector Llc |
Anti-siglec-9 antibodies and methods of use thereof
|
CA3004299A1
(en)
|
2015-11-05 |
2017-05-11 |
City Of Hope |
Methods for preparing cells for adoptive t cell therapy
|
ES2873846T3
(en)
|
2015-11-19 |
2021-11-04 |
Revitope Ltd |
Functional Antibody Fragment Complementation for a Two-Component System for Targeted Elimination of Unwanted Cells
|
CN108136022A
(en)
|
2015-11-19 |
2018-06-08 |
豪夫迈·罗氏有限公司 |
Use B-RAF inhibitor and the method for immunologic test point inhibitor for treating cancer
|
KR20180133840A
(en)
|
2015-12-04 |
2018-12-17 |
노파르티스 아게 |
Compositions and methods for immuno-oncology
|
EP3402516A4
(en)
|
2016-01-12 |
2020-01-08 |
Palleon Pharmaceuticals Inc. |
Use of siglec-7 or siglec-9 antibodies for the treatment of cancer
|
US9624185B1
(en)
|
2016-01-20 |
2017-04-18 |
Yong Xu |
Method for preparing IDO inhibitor epacadostat
|
CN105968204B
(en)
|
2016-02-03 |
2020-01-21 |
中国人民解放军第三军医大学第一附属医院 |
Single-domain heavy chain antibody for resisting prostate specific membrane antigen
|
EP3411380A4
(en)
|
2016-02-03 |
2020-01-22 |
Youhealth Biotech, Limited |
Compounds for treating eye disorders or diseases
|
CN105968201A
(en)
|
2016-02-03 |
2016-09-28 |
南昌大学 |
Single-domain heavy-chain antibody aiming at prostate specific membrane antigen
|
MA43955B1
(en)
|
2016-02-03 |
2022-02-28 |
Amgen Inc |
Bite-format bispecific anti-bcma and anti-cd3 antibodies
|
AU2017229687A1
(en)
|
2016-03-08 |
2018-09-20 |
Takeda Pharmaceutical Company Limited |
Inducible binding proteins and methods of use
|
WO2017157305A1
(en)
|
2016-03-15 |
2017-09-21 |
Generon (Shanghai) Corporation Ltd. |
Multispecific fab fusion proteins and use thereof
|
WO2017161206A1
(en)
|
2016-03-16 |
2017-09-21 |
Halozyme, Inc. |
Conjugates containing conditionally active antibodies or antigen-binding fragments thereof, and methods of use
|
CR20180453A
(en)
|
2016-03-22 |
2018-12-05 |
Hoffmann La Roche |
Bispecific MOLECULES OF T-CELLS ACTIVATED BY PROTEASES
|
US11046782B2
(en)
|
2016-03-30 |
2021-06-29 |
Musc Foundation For Research Development |
Methods for treatment and diagnosis of cancer by targeting glycoprotein A repetitions predominant (GARP) and for providing effective immunotherapy alone or in combination
|
US11623958B2
(en)
|
2016-05-20 |
2023-04-11 |
Harpoon Therapeutics, Inc. |
Single chain variable fragment CD3 binding proteins
|
AU2017267793B2
(en)
|
2016-05-20 |
2024-01-25 |
Harpoon Therapeutics, Inc. |
Single chain variable fragment CD3 binding proteins
|
JP7101621B2
(en)
|
2016-05-20 |
2022-07-15 |
ハープーン セラピューティクス,インク. |
Single domain serum albumin binding protein
|
US20190201542A1
(en)
|
2016-05-20 |
2019-07-04 |
Abbvie Stemcentrx Llc |
Anti-dll3 drug conjugates for treating tumors at risk of neuroendocrine transition
|
WO2017210443A1
(en)
|
2016-06-01 |
2017-12-07 |
Xencor, Inc. |
Bispecific antibodies that bind cd123 and cd3
|
JP7261379B2
(en)
|
2016-06-20 |
2023-04-20 |
カイマブ・リミテッド |
Anti-PD-L1 antibody
|
WO2018017864A2
(en)
|
2016-07-20 |
2018-01-25 |
Oncomed Pharmaceuticals, Inc. |
Pvrig-binding agents and uses thereof
|
TW201815825A
(en)
|
2016-07-21 |
2018-05-01 |
財團法人生物技術開發中心 |
Modified antigen-binding FAB fragments and antigen-binding molecules comprising the same
|
CA3032498A1
(en)
*
|
2016-08-02 |
2018-02-08 |
TCR2 Therapeutics Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
US11773162B2
(en)
|
2016-08-05 |
2023-10-03 |
Allakos, Inc. |
Anti-Siglec-7 antibodies for the treatment of cancer
|
US11324744B2
(en)
|
2016-08-08 |
2022-05-10 |
Acetylon Pharmaceuticals Inc. |
Methods of use and pharmaceutical combinations of histone deacetylase inhibitors and CD20 inhibitory antibodies
|
EP3347379B9
(en)
|
2016-08-17 |
2020-03-25 |
Compugen Ltd. |
Anti-tigit antibodies, anti-pvrig antibodies and combinations thereof
|
WO2018048975A1
(en)
|
2016-09-09 |
2018-03-15 |
Bristol-Myers Squibb Company |
Use of an anti-pd-1 antibody in combination with an anti-mesothelin antibody in cancer treatment
|
CN109689686B
(en)
|
2016-10-07 |
2020-08-25 |
T细胞受体治疗公司 |
Compositions and methods for T cell receptor weight programming using fusion proteins
|
US20190225702A1
(en)
|
2016-10-14 |
2019-07-25 |
Harpoon Therapeutics, Inc. |
Innate immune cell trispecific binding proteins and methods of use
|
WO2018075359A1
(en)
|
2016-10-18 |
2018-04-26 |
Boger Henry William |
Wireless power transfer for process control
|
SG11201903867YA
(en)
|
2016-11-01 |
2019-05-30 |
Anaptysbio Inc |
Antibodies directed against t cell immunoglobulin and mucin protein 3 (tim-3)
|
JP7267914B2
(en)
|
2016-11-02 |
2023-05-02 |
エンクマフ エスアーエールエル |
Bispecific antibodies to BCMA and CD3 and immunotherapeutic agents used in combination to treat multiple myeloma
|
US10844134B2
(en)
|
2016-11-23 |
2020-11-24 |
Harpoon Therapeutics, Inc. |
PSMA targeting trispecific proteins and methods of use
|
CN110198955A
(en)
|
2016-11-23 |
2019-09-03 |
哈普恩治疗公司 |
Prostate-specific membrane antigen conjugated protein
|
CN110023338A
(en)
|
2016-12-08 |
2019-07-16 |
伊莱利利公司 |
For the anti-TIM-3 antibody with anti-PD-L1 antibody combination
|
JOP20190133A1
(en)
|
2016-12-08 |
2019-06-02 |
Innovent Biologics Suzhou Co Ltd |
Anti-tim-3 antibodies for combination with anti-pd-1 antibodies
|
MX2019006897A
(en)
|
2016-12-13 |
2019-08-22 |
Astellas Pharma Inc |
Anti-human cd73 antibody.
|
WO2018115859A1
(en)
|
2016-12-20 |
2018-06-28 |
Kymab Limited |
Multispecific antibody with combination therapy for immuno-oncology
|
WO2018136725A1
(en)
|
2017-01-19 |
2018-07-26 |
Harpoon Therapeutics, Inc. |
Innate immune cell inducible binding proteins and methods of use
|
CN111574628B
(en)
|
2017-01-23 |
2023-08-08 |
克莱格医学有限公司 |
Antibodies targeting BCMA and uses thereof
|
WO2018160671A1
(en)
|
2017-02-28 |
2018-09-07 |
Harpoon Therapeutics, Inc. |
Targeted checkpoint inhibitors and methods of use
|
EP3589662A4
(en)
|
2017-02-28 |
2020-12-30 |
Harpoon Therapeutics, Inc. |
Inducible monovalent antigen binding protein
|
KR20190134654A
(en)
|
2017-03-09 |
2019-12-04 |
싸이톰스 테라퓨틱스, 인크. |
CD147 antibody, activatable CD147 antibody, and how to make and use it
|
WO2018183366A1
(en)
|
2017-03-28 |
2018-10-04 |
Syndax Pharmaceuticals, Inc. |
Combination therapies of csf-1r or csf-1 antibodies and a t-cell engaging therapy
|
EP3619234A4
(en)
|
2017-05-03 |
2021-05-26 |
Harpoon Therapeutics, Inc. |
Compositions and methods for adoptive cell therapies
|
AU2018265856B2
(en)
|
2017-05-12 |
2023-04-27 |
Harpoon Therapeutics, Inc. |
Mesothelin binding proteins
|
US20200270362A1
(en)
|
2017-05-12 |
2020-08-27 |
Harpoon Therapeutics, Inc. |
Msln targeting trispecific proteins and methods of use
|
CA3063362A1
(en)
|
2017-05-12 |
2018-11-15 |
Harpoon Therapeutics, Inc. |
Msln targeting trispecific proteins and methods of use
|
CN111247167A
(en)
|
2017-06-02 |
2020-06-05 |
辉瑞公司 |
Antibodies specific for FLT3 and uses thereof
|
WO2018232020A1
(en)
|
2017-06-13 |
2018-12-20 |
TCR2 Therapeutics Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
AU2018298673A1
(en)
|
2017-07-10 |
2019-12-19 |
Innate Pharma |
Combination therapy using antibody to human Siglec-9 and antibody to human NKG2A for treating cancer
|
CN111263769B
(en)
|
2017-07-10 |
2024-01-02 |
先天制药公司 |
SIGLEC-9 neutralizing antibodies
|
EP3661963A1
(en)
|
2017-08-01 |
2020-06-10 |
MedImmune, LLC |
Bcma monoclonal antibody-drug conjugate
|
JP7147270B2
(en)
|
2017-09-15 |
2022-10-05 |
日本電産株式会社 |
transmission and actuator
|
CR20200196A
(en)
*
|
2017-10-13 |
2020-06-05 |
Harpoon Therapeutics Inc |
Trispecific proteins and methods of use
|
SG11202003341UA
(en)
|
2017-10-13 |
2020-05-28 |
Harpoon Therapeutics Inc |
B cell maturation antigen binding proteins
|
WO2019089848A1
(en)
|
2017-11-01 |
2019-05-09 |
Juno Therapeutics, Inc. |
Methods associated with tumor burden for assessing response to a cell therapy
|
WO2019136305A1
(en)
|
2018-01-04 |
2019-07-11 |
Neumedicines Inc. |
Cell-based and immune checkpoint inhibitor therapies combined with il-12 for treating cancer
|
CA3089230A1
(en)
|
2018-03-02 |
2019-09-06 |
Cdr-Life Ag |
Trispecific antigen binding proteins
|
US20210292421A1
(en)
|
2018-05-14 |
2021-09-23 |
Harpoon Therapeutics, Inc. |
Binding moiety for conditional activation of immunoglobulin molecules
|
EP3794044A4
(en)
|
2018-05-14 |
2022-02-16 |
Harpoon Therapeutics, Inc. |
Dual binding moiety
|
US20210269530A1
(en)
|
2018-05-14 |
2021-09-02 |
Harpoon Therapeutics, Inc. |
Conditionally activated binding protein comprising a sterically occluded target binding domain
|
PE20210320A1
(en)
|
2018-06-01 |
2021-02-16 |
Novartis Ag |
BINDING MOLECULES AGAINST BCMA AND THE USES OF THEM
|
JP2021529516A
(en)
|
2018-06-18 |
2021-11-04 |
アンウィタ バイオサイエンシス, インク. |
Cytokine fusion protein and its use
|
AU2019337974A1
(en)
|
2018-09-11 |
2021-04-08 |
iTeos Belgium SA |
Thiocarbamate derivatives as A2A inhibitors, pharmaceutical composition thereof and combinations with anticancer agents
|
US20220017626A1
(en)
|
2018-09-21 |
2022-01-20 |
Harpoon Therapeutics, Inc. |
Egfr binding proteins and methods of use
|
WO2020060593A1
(en)
|
2018-09-21 |
2020-03-26 |
Harpoon Therapeutics, Inc. |
Conditionally active receptors
|
US20210355219A1
(en)
|
2018-09-21 |
2021-11-18 |
Harpoon Therapeutics, Inc. |
Conditionally activated target-binding molecules
|
US10815311B2
(en)
|
2018-09-25 |
2020-10-27 |
Harpoon Therapeutics, Inc. |
DLL3 binding proteins and methods of use
|
US20220000872A1
(en)
|
2018-10-31 |
2022-01-06 |
Oncotracker, Inc. |
Method of enhancing immune-based therapy
|
JP2022512971A
(en)
|
2018-11-08 |
2022-02-07 |
ジュノー セラピューティクス インコーポレイテッド |
Methods and combinations for treatment and T cell regulation
|
CN109593786A
(en)
|
2019-01-09 |
2019-04-09 |
上海怡豪生物科技有限公司 |
The double target spot CAR carriers and its construction method of joint EpCAM and MSLN single-chain antibody and in breast cancer application
|
AU2020231391A1
(en)
|
2019-03-05 |
2021-10-28 |
Takeda Pharmaceutical Company Limited |
Conditionally activated binding proteins containing Fc regions and moieties targeting tumor antigens
|
CA3140430A1
(en)
|
2019-05-14 |
2020-11-19 |
Harpoon Therapeutics, Inc. |
Epcam binding proteins and methods of use
|
JP2022536511A
(en)
|
2019-06-13 |
2022-08-17 |
シートムエックス セラピューティクス,インコーポレイテッド |
Use of activatable anti-PDL1 and anti-CTLA-4 antibodies in combination therapy for the treatment of cancer
|
WO2020261093A1
(en)
|
2019-06-24 |
2020-12-30 |
Novartis Ag |
Dosing regimen and combination therapies for multispecific antibodies targeting b-cell maturation antigen
|
CR20210687A
(en)
|
2019-06-25 |
2022-03-03 |
Gilead Sciences Inc |
Flt3l-fc fusion proteins and methods of use
|
WO2021097060A1
(en)
|
2019-11-13 |
2021-05-20 |
Harpoon Therapeutics, Inc. |
Pro immune modulating molecule comprising a clustering moiety
|
JP2023527609A
(en)
|
2020-02-21 |
2023-06-30 |
ハープーン セラピューティクス,インク. |
FLT3 binding proteins and methods of use
|
WO2021231434A1
(en)
|
2020-05-12 |
2021-11-18 |
Harpoon Therapeutics, Inc. |
Psma targeting tritacs and methods of use
|
WO2022032006A2
(en)
|
2020-08-05 |
2022-02-10 |
Synthekine, Inc. |
Il2rb binding molecules and methods of use
|
US20230272094A1
(en)
|
2020-08-05 |
2023-08-31 |
Synthekine, Inc. |
Il2rb/il2rg synthetic cytokines
|
WO2022098909A1
(en)
|
2020-11-06 |
2022-05-12 |
Harpoon Therapeutics, Inc. |
Epcam targeting trispecific protein for treatment of cancer
|
WO2022212732A1
(en)
|
2021-04-01 |
2022-10-06 |
Harpoon Therapeutics, Inc. |
Psma targeting tritacs and methods of use
|
WO2022256500A2
(en)
|
2021-06-03 |
2022-12-08 |
Harpoon Therapeutics, Inc. |
Dll3 targeting trispecific proteins and methods of use
|
WO2022256498A1
(en)
|
2021-06-03 |
2022-12-08 |
Harpoon Therapeutics, Inc. |
Msln targeting trispecific proteins and methods of use
|
WO2022256499A2
(en)
|
2021-06-03 |
2022-12-08 |
Harpoon Therapeutics, Inc. |
Bcma targeting trispecific proteins and methods of use
|
EP4359443A2
(en)
|
2021-06-25 |
2024-05-01 |
Harpoon Therapeutics, Inc. |
Extended-release immune cell engaging proteins and methods of treatment
|
WO2023064945A2
(en)
|
2021-10-15 |
2023-04-20 |
Harpoon Therapeutics, Inc. |
Conditional activation of immunoglobulin molecules
|