SG11202000168UA - Ask1 inhibiting pyrrolopyrimidine and pyrrolopyridine derivatives - Google Patents
Ask1 inhibiting pyrrolopyrimidine and pyrrolopyridine derivativesInfo
- Publication number
- SG11202000168UA SG11202000168UA SG11202000168UA SG11202000168UA SG11202000168UA SG 11202000168U A SG11202000168U A SG 11202000168UA SG 11202000168U A SG11202000168U A SG 11202000168UA SG 11202000168U A SG11202000168U A SG 11202000168UA SG 11202000168U A SG11202000168U A SG 11202000168UA
- Authority
- SG
- Singapore
- Prior art keywords
- pyrrolopyrimidine
- pyrrolopyridine derivatives
- ask1
- inhibiting
- ask1 inhibiting
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1711234.3A GB201711234D0 (en) | 2017-07-12 | 2017-07-12 | Pyrrolopyrimidine and pyrrolopyridine derivatives |
| PCT/GB2018/051983 WO2019012284A1 (en) | 2017-07-12 | 2018-07-12 | Ask1 inhibiting pyrrolopyrimidine and pyrrolopyridine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202000168UA true SG11202000168UA (en) | 2020-02-27 |
Family
ID=59676761
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202000168UA SG11202000168UA (en) | 2017-07-12 | 2018-07-12 | Ask1 inhibiting pyrrolopyrimidine and pyrrolopyridine derivatives |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US11136325B2 (en) |
| EP (1) | EP3652173A1 (en) |
| JP (1) | JP7198263B2 (en) |
| KR (1) | KR20200028436A (en) |
| CN (1) | CN111094283A (en) |
| AR (1) | AR112333A1 (en) |
| AU (1) | AU2018300218B2 (en) |
| BR (1) | BR112020000578A2 (en) |
| CA (1) | CA3069358A1 (en) |
| CO (1) | CO2020001346A2 (en) |
| GB (1) | GB201711234D0 (en) |
| IL (1) | IL271910B2 (en) |
| MX (1) | MX2020000005A (en) |
| PH (1) | PH12019502823A1 (en) |
| SG (1) | SG11202000168UA (en) |
| TW (1) | TWI794253B (en) |
| UY (1) | UY37809A (en) |
| WO (1) | WO2019012284A1 (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201711234D0 (en) * | 2017-07-12 | 2017-08-23 | Galapagos Nv | Pyrrolopyrimidine and pyrrolopyridine derivatives |
| CN111303155A (en) * | 2020-03-13 | 2020-06-19 | 深圳大学 | Targeted PAK1 inhibitor and application thereof in antitumor treatment drugs |
| CN111704617B (en) * | 2020-06-15 | 2022-08-23 | 嘉兴特科罗生物科技有限公司 | Small molecule compound |
| KR102635126B1 (en) * | 2021-05-27 | 2024-02-13 | 한국과학기술연구원 | Novel pyrrolopyrimidine derivatives as a Ectonucleotide pyrophosphatase-phosphodiesterase inhibitors and use thereof |
| WO2023009642A1 (en) * | 2021-07-28 | 2023-02-02 | Epirium Bio Inc. | Pyrrolo[2,3-b]pyridine pgdh inhibitors and methods of making and using |
| KR20230019801A (en) * | 2021-08-02 | 2023-02-09 | 한국화학연구원 | Novel pyrrlopyrimidine derivatives compound, preparing method thereof, and pharmaceutical composition for preventing or treating metabolic liver related diseases containing the same as an active ingredient |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1246623T3 (en) | 1999-12-02 | 2006-11-13 | Osi Pharm Inc | Compounds specific for adenosine A1, A2a, and A3 receptor and uses thereof |
| TW200306191A (en) * | 2002-02-22 | 2003-11-16 | Teijin Ltd | Pyrrolopyrimidine derivatives |
| EP1582586A4 (en) | 2002-11-22 | 2007-03-14 | Takeda Pharmaceutical | Apoptosis-associated protein and use thereof |
| US20100029619A1 (en) | 2006-08-04 | 2010-02-04 | Takeda Pharmaceutical Company Limted | Fused heterocyclic compound |
| WO2008075172A2 (en) | 2006-12-19 | 2008-06-26 | Pfizer Products Inc. | Nicotinamide derivatives as inhibitors of h-pgds and their use for treating prostaglandin d2 mediated diseases |
| CA2691448A1 (en) | 2007-08-31 | 2009-03-05 | Dominique Swinnen | Triazolopyridine compounds and their use as ask inhibitors |
| JP5432982B2 (en) | 2008-03-31 | 2014-03-05 | 武田薬品工業株式会社 | Apoptosis signal-regulating kinase 1 inhibitor |
| TWI598347B (en) | 2009-07-13 | 2017-09-11 | 基利科學股份有限公司 | Apoptosis signal-regulating kinase inhibitors |
| EP2651417B1 (en) | 2010-12-16 | 2016-11-30 | Calchan Limited | Ask1 inhibiting pyrrolopyrimidine derivatives |
| GB201711234D0 (en) * | 2017-07-12 | 2017-08-23 | Galapagos Nv | Pyrrolopyrimidine and pyrrolopyridine derivatives |
-
2017
- 2017-07-12 GB GBGB1711234.3A patent/GB201711234D0/en not_active Ceased
-
2018
- 2018-07-12 BR BR112020000578-9A patent/BR112020000578A2/en unknown
- 2018-07-12 AR ARP180101945 patent/AR112333A1/en unknown
- 2018-07-12 KR KR1020207004013A patent/KR20200028436A/en not_active Application Discontinuation
- 2018-07-12 UY UY0001037809A patent/UY37809A/en not_active Application Discontinuation
- 2018-07-12 EP EP18745683.5A patent/EP3652173A1/en active Pending
- 2018-07-12 CA CA3069358A patent/CA3069358A1/en active Pending
- 2018-07-12 AU AU2018300218A patent/AU2018300218B2/en not_active Ceased
- 2018-07-12 CN CN201880045891.9A patent/CN111094283A/en active Pending
- 2018-07-12 WO PCT/GB2018/051983 patent/WO2019012284A1/en unknown
- 2018-07-12 SG SG11202000168UA patent/SG11202000168UA/en unknown
- 2018-07-12 TW TW107124084A patent/TWI794253B/en active
- 2018-07-12 JP JP2020501447A patent/JP7198263B2/en active Active
- 2018-07-12 MX MX2020000005A patent/MX2020000005A/en unknown
- 2018-07-12 US US16/632,202 patent/US11136325B2/en active Active
-
2019
- 2019-12-13 PH PH12019502823A patent/PH12019502823A1/en unknown
-
2020
- 2020-01-08 IL IL271910A patent/IL271910B2/en unknown
- 2020-02-06 CO CONC2020/0001346A patent/CO2020001346A2/en unknown
-
2021
- 2021-09-03 US US17/466,230 patent/US20220169653A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2020530833A (en) | 2020-10-29 |
| RU2020106289A3 (en) | 2021-11-10 |
| WO2019012284A1 (en) | 2019-01-17 |
| AU2018300218B2 (en) | 2021-12-16 |
| US11136325B2 (en) | 2021-10-05 |
| RU2020106289A (en) | 2021-08-12 |
| CO2020001346A2 (en) | 2020-05-29 |
| KR20200028436A (en) | 2020-03-16 |
| UY37809A (en) | 2019-02-28 |
| IL271910B2 (en) | 2023-07-01 |
| PH12019502823A1 (en) | 2020-10-26 |
| CA3069358A1 (en) | 2019-01-17 |
| US20220169653A1 (en) | 2022-06-02 |
| MX2020000005A (en) | 2020-08-06 |
| TW201908312A (en) | 2019-03-01 |
| GB201711234D0 (en) | 2017-08-23 |
| CN111094283A (en) | 2020-05-01 |
| EP3652173A1 (en) | 2020-05-20 |
| IL271910A (en) | 2020-02-27 |
| IL271910B1 (en) | 2023-03-01 |
| TWI794253B (en) | 2023-03-01 |
| AR112333A1 (en) | 2019-10-16 |
| AU2018300218A1 (en) | 2020-02-27 |
| US20200165259A1 (en) | 2020-05-28 |
| BR112020000578A2 (en) | 2020-07-14 |
| JP7198263B2 (en) | 2022-12-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL265922A (en) | Tyk2 inhibitors and uses thereof | |
| IL271999A (en) | Tyk2 inhibitors and uses thereof | |
| IL266109A (en) | Tyk2 inhibitors and uses thereof | |
| EP3572401A4 (en) | Ask1 inhibitor and preparation method and use thereof | |
| IL261885A (en) | Pyrazolopyrimidine derivatives | |
| IL271964A (en) | Macrocyclic compounds and uses thereof | |
| IL271910B1 (en) | Ask1 inhibiting pyrrolopyrimidine and pyrrolopyridine derivatives | |
| IL269711A (en) | Ask1 inhibitor compounds and uses thereof | |
| IL274534A (en) | Processes for the resolution of benzodiazepin-2-one and benzodiazepin-2-one derivatives | |
| PT3359004T (en) | Modular barbecue system and kits therefore | |
| GB201615282D0 (en) | Tankyrase inhibitors | |
| IL288991A (en) | Macrocyclic compound and uses thereof | |
| HK1248215A1 (en) | Ergoline compounds and uses thereof | |
| IL284139A (en) | Imidazopyridazine and imidazopyridine compounds and uses thereof | |
| IL270011B (en) | Therapeutic compounds and methods | |
| HK1252428A1 (en) | Bicyclic compound and use thereof for inhibiting suv39h2 | |
| PL3359543T3 (en) | Cucurbituril derivatives | |
| IL274868A (en) | Imidazopyridine derivatives and the use thereof as medicament | |
| IL279709A (en) | Ask1 inhibiting agents | |
| GB201719043D0 (en) | Methods and compounds |