SG11201913178WA - Non human great apes adenovirus nucleic acid- and amino acid-sequences, vectors containing same, and uses thereof - Google Patents

Non human great apes adenovirus nucleic acid- and amino acid-sequences, vectors containing same, and uses thereof

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Publication number
SG11201913178WA
SG11201913178WA SG11201913178WA SG11201913178WA SG11201913178WA SG 11201913178W A SG11201913178W A SG 11201913178WA SG 11201913178W A SG11201913178W A SG 11201913178WA SG 11201913178W A SG11201913178W A SG 11201913178WA SG 11201913178W A SG11201913178W A SG 11201913178WA
Authority
SG
Singapore
Prior art keywords
sequences
vectors containing
amino acid
nucleic acid
containing same
Prior art date
Application number
SG11201913178WA
Inventor
Alfredo Nicosia
Stefano Colloca
Armin Lahm
Original Assignee
Nouscom Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nouscom Ag filed Critical Nouscom Ag
Publication of SG11201913178WA publication Critical patent/SG11201913178WA/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/235Adenoviridae
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10321Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10323Virus like particles [VLP]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG11201913178WA 2017-07-05 2018-07-05 Non human great apes adenovirus nucleic acid- and amino acid-sequences, vectors containing same, and uses thereof SG11201913178WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17179825 2017-07-05
PCT/EP2018/068291 WO2019008111A1 (en) 2017-07-05 2018-07-05 Non human great apes adenovirus nucleic acid- and amino acid-sequences, vectors containing same, and uses thereof

Publications (1)

Publication Number Publication Date
SG11201913178WA true SG11201913178WA (en) 2020-01-30

Family

ID=59295008

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201913178WA SG11201913178WA (en) 2017-07-05 2018-07-05 Non human great apes adenovirus nucleic acid- and amino acid-sequences, vectors containing same, and uses thereof

Country Status (18)

Country Link
US (1) US11098324B2 (en)
EP (1) EP3649237B1 (en)
JP (1) JP7274222B2 (en)
KR (1) KR102582561B1 (en)
CN (1) CN111108192B (en)
AU (1) AU2018295421B2 (en)
BR (1) BR112020000145A2 (en)
CA (1) CA3066962A1 (en)
DK (1) DK3649237T3 (en)
ES (1) ES2906441T3 (en)
HU (1) HUE058778T2 (en)
IL (1) IL271835B2 (en)
MX (1) MX2020000221A (en)
PL (1) PL3649237T3 (en)
PT (1) PT3649237T (en)
RU (1) RU2762854C2 (en)
SG (1) SG11201913178WA (en)
WO (1) WO2019008111A1 (en)

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* Cited by examiner, † Cited by third party
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EP3587581A1 (en) 2018-06-26 2020-01-01 GlaxoSmithKline Biologicals S.A. Formulations for simian adenoviral vectors having enhanced storage stability
TW202043256A (en) 2019-01-10 2020-12-01 美商健生生物科技公司 Prostate neoantigens and their uses
US12018289B2 (en) 2019-11-18 2024-06-25 Janssen Biotech, Inc. Vaccines based on mutant CALR and JAK2 and their uses
TW202144388A (en) 2020-02-14 2021-12-01 美商健生生物科技公司 Neoantigens expressed in ovarian cancer and their uses
TW202144389A (en) 2020-02-14 2021-12-01 美商健生生物科技公司 Neoantigens expressed in multiple myeloma and their uses
US20230110451A1 (en) 2020-02-27 2023-04-13 Amorepacific Corporation Composition having improved usability
JP2023521194A (en) 2020-04-13 2023-05-23 ヤンセン バイオテツク,インコーポレーテツド PSMA and STEAP1 vaccines and their uses
EP4150344A1 (en) 2020-05-14 2023-03-22 GlaxoSmithKline Biologicals SA Viral biosensors
TW202208398A (en) * 2020-07-01 2022-03-01 義大利商萊伊錫拉有限責任公司 Gorilla adenovirus nucleic acid- and amino acid-sequences, vectors containing same, and uses thereof
EP4175721A1 (en) 2020-07-06 2023-05-10 Janssen Biotech, Inc. Prostate neoantigens and their uses
WO2022009052A2 (en) 2020-07-06 2022-01-13 Janssen Biotech, Inc. Prostate neoantigens and their uses
EP4177347A1 (en) * 2020-07-06 2023-05-10 Jiaxing Anyu Biotechnology Co., Ltd Novel chimpanzee adenovirus vector, construction method therefor, and application thereof
EP4176087A1 (en) 2020-07-06 2023-05-10 Janssen Biotech, Inc. A method for determining responsiveness to prostate cancer treatment
WO2024128524A1 (en) * 2022-12-16 2024-06-20 주식회사 아바타테라퓨틱스 Method for producing high yield and high quality recombinant adeno-associated virus

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EP0787200B1 (en) 1994-10-28 2005-04-20 The Trustees Of The University Of Pennsylvania Improved adenovirus and methods of use thereof
US5922315A (en) 1997-01-24 1999-07-13 Genetic Therapy, Inc. Adenoviruses having altered hexon proteins
US20030224372A1 (en) 2002-05-31 2003-12-04 Denise Syndercombe-Court Method for determining ethnic origin by means of STR profile
DE602005017743D1 (en) 2004-01-23 2009-12-31 Angeletti P Ist Richerche Bio VACCINE CARRIER FOR CHIMPANE ADENOVIRUS
MX2007004188A (en) * 2004-10-13 2007-10-11 Crucell Holland Bv Improved adenoviral vectors and uses thereof.
JP4843613B2 (en) * 2004-10-13 2011-12-21 クルセル ホランド ベー ヴェー Improved adenoviral vectors and methods of use thereof
CA2597404A1 (en) 2005-02-11 2006-08-17 Merck & Co. Inc. Adenovirus serotype 26 vectors, nucleic acid and viruses produced thereby
EP2350269B1 (en) * 2008-10-31 2015-09-09 The Trustees Of The University Of Pennsylvania Simian adenoviruses with sadv-46 hexon capsid proteins and uses thereof
MX2011007980A (en) * 2009-02-02 2011-08-17 Okairos Ag Simian adenovirus nucleic acid- and amino acid-sequences, vectors containing same, and uses thereof.
WO2010085984A1 (en) * 2009-02-02 2010-08-05 Okairos Ag Simian adenovirus nucleic acid- and amino acid-sequences, vectors containing same, and uses thereof
WO2012023995A1 (en) * 2010-08-18 2012-02-23 Takayuki Shiratsuchi Modification of recombinant adenovirus capsid protein with immunogenic plasmodium circumsporozoite protein epitopes
US20140348791A1 (en) * 2011-09-09 2014-11-27 Beth Israel Deaconess Medical Center, Inc. Modified adenoviral vectors and methods of treatment using same
BR112014008167B1 (en) * 2011-10-05 2022-05-24 Genvec Inc Adenovirus or adenoviral vector and composition comprising them
WO2013116591A1 (en) * 2012-02-02 2013-08-08 Genvec, Inc. Adenoviral vector-based malaria vaccine
CN103966263A (en) * 2013-02-04 2014-08-06 广州医学院第一附属医院 Recombinant human adenovirus 3, and preparation method and application thereof
CN104419717B (en) * 2013-08-23 2018-04-27 长春百克生物科技股份公司 Escape the recombined adhenovirus and its construction method and purposes of pre-existing immunity
EP3723771A4 (en) * 2017-12-11 2022-04-06 Beth Israel Deaconess Medical Center, Inc. Recombinant adenoviruses and uses thereof
TW202208398A (en) * 2020-07-01 2022-03-01 義大利商萊伊錫拉有限責任公司 Gorilla adenovirus nucleic acid- and amino acid-sequences, vectors containing same, and uses thereof

Also Published As

Publication number Publication date
IL271835B1 (en) 2023-04-01
ES2906441T3 (en) 2022-04-18
PT3649237T (en) 2022-02-14
IL271835B2 (en) 2023-08-01
IL271835A (en) 2020-02-27
RU2762854C2 (en) 2021-12-23
DK3649237T3 (en) 2022-02-21
EP3649237A1 (en) 2020-05-13
KR102582561B1 (en) 2023-09-26
PL3649237T3 (en) 2022-03-28
WO2019008111A1 (en) 2019-01-10
MX2020000221A (en) 2020-08-13
RU2019144161A3 (en) 2021-08-05
JP7274222B2 (en) 2023-05-16
RU2019144161A (en) 2021-08-05
BR112020000145A2 (en) 2020-07-14
JP2020530761A (en) 2020-10-29
US11098324B2 (en) 2021-08-24
AU2018295421B2 (en) 2024-01-25
HUE058778T2 (en) 2022-09-28
NZ759892A (en) 2023-09-29
KR20200024296A (en) 2020-03-06
CN111108192A (en) 2020-05-05
US20210130848A1 (en) 2021-05-06
CN111108192B (en) 2023-12-15
EP3649237B1 (en) 2022-01-19
AU2018295421A1 (en) 2020-01-02
CA3066962A1 (en) 2019-01-10

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