SG11201912267SA - Nicotinamide riboside derivatives and their uses - Google Patents
Nicotinamide riboside derivatives and their usesInfo
- Publication number
- SG11201912267SA SG11201912267SA SG11201912267SA SG11201912267SA SG11201912267SA SG 11201912267S A SG11201912267S A SG 11201912267SA SG 11201912267S A SG11201912267S A SG 11201912267SA SG 11201912267S A SG11201912267S A SG 11201912267SA SG 11201912267S A SG11201912267S A SG 11201912267SA
- Authority
- SG
- Singapore
- Prior art keywords
- nicotinamide riboside
- riboside derivatives
- derivatives
- nicotinamide
- riboside
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/048—Pyridine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762521717P | 2017-06-19 | 2017-06-19 | |
PCT/US2018/038201 WO2018236814A2 (en) | 2017-06-19 | 2018-06-19 | Nicotinamide riboside derivatives and their uses |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201912267SA true SG11201912267SA (en) | 2020-01-30 |
Family
ID=62875307
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201912267SA SG11201912267SA (en) | 2017-06-19 | 2018-06-19 | Nicotinamide riboside derivatives and their uses |
Country Status (4)
Country | Link |
---|---|
US (1) | US11286274B2 (en) |
EP (1) | EP3642214A2 (en) |
SG (1) | SG11201912267SA (en) |
WO (1) | WO2018236814A2 (en) |
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WO2019089417A1 (en) * | 2017-10-30 | 2019-05-09 | Elysium Health, Inc. | Methods and compositions for treating cystic fibrosis |
US20200384004A1 (en) * | 2017-12-01 | 2020-12-10 | Elysium Health, Inc. | Methods and compositions for treating glaucoma |
CN108841781A (en) * | 2018-06-13 | 2018-11-20 | 延边大学 | Crocin is improving the application in porcine oocytes oxidation resistance and cleavage rates |
US11833167B2 (en) | 2018-12-17 | 2023-12-05 | Mitopower Llc | Nicotinyl riboside compounds and their uses |
US11266696B2 (en) * | 2019-01-18 | 2022-03-08 | Americord Registry Llc | Method of treating stem cells with NAD |
CN109674808A (en) * | 2019-01-30 | 2019-04-26 | 四川大学 | β-nicotinamide mononucleotide or its precursor are preparing the purposes delayed in lung senescence drug |
WO2020191359A1 (en) * | 2019-03-21 | 2020-09-24 | Fred Hutchinson Cancer Research Center | Cancer combination therapies utilizing a nicotinamide phosphoribosyltransferase inhibitor in combination with a nicotinamide adenine dinucleotide salvage pathway precursor |
WO2020190703A1 (en) * | 2019-03-21 | 2020-09-24 | Elysium Health, Inc. | Methods for wound treatment |
CA3141641A1 (en) * | 2019-06-05 | 2020-12-10 | Societe Des Produits Nestle S.A. | Reduced nicotinamideribosides for treating/preventing skeletal muscle disease |
US20220296623A1 (en) * | 2019-06-05 | 2022-09-22 | Societe Des Produits Nestle S.A. | Reduced nicotinamideribosides for treating or preventing kidney disease |
EP3980027A1 (en) * | 2019-06-05 | 2022-04-13 | Société des Produits Nestlé S.A. | Reduced nicotinamideribosides for the treatment/prevention of liver disease |
EP3986420A1 (en) * | 2019-06-18 | 2022-04-27 | Mitopower LLC | Nicotinyl riboside compounds and their uses |
WO2021021668A1 (en) * | 2019-07-26 | 2021-02-04 | Allegro Pharmaceuticals, LLC | Peptides for treating non-exudative macular degeneration and other disorders of the eye |
FR3102058A1 (en) * | 2019-10-18 | 2021-04-23 | Nuvamid Sa | Use of NMN for the prevention and / or treatment of rheumatoid arthritis and corresponding compositions |
JP2022554277A (en) * | 2019-10-30 | 2022-12-28 | パフューズ セラピューティクス, インコーポレイテッド | Treatment of eye disease using endothelin receptor antagonists |
WO2021098725A1 (en) * | 2019-11-19 | 2021-05-27 | Tsinghua University | Synthetic method for nmn derivative and medical applications of nmn and its derivative |
CN115103842A (en) | 2020-02-06 | 2022-09-23 | 珀弗斯治疗股份有限公司 | Compositions for treating ocular diseases |
KR20220151628A (en) * | 2020-03-06 | 2022-11-15 | 알레그로 파마슈티칼스, 엘엘씨 | Treatment to improve or reduce impairment of mitochondrial function |
CN115066246A (en) * | 2020-03-09 | 2022-09-16 | 雀巢产品有限公司 | Compositions and methods comprising reduced nicotinamide riboside for the prevention and treatment of viral and bacterial infections |
WO2021180741A1 (en) * | 2020-03-09 | 2021-09-16 | Société des Produits Nestlé S.A. | Compositions and methods containing reduced nicotinamide riboside for prevention and treatment of pancreatic diseases and conditions |
FR3108502B1 (en) * | 2020-03-27 | 2022-09-23 | Nuvamid Sa | NICOTINAMIDE MONONUCLEOTIDE DERIVATIVES IN THE TREATMENT AND PREVENTION OF BACTERIAL INFECTIONS |
CN111454311B (en) * | 2020-04-03 | 2021-10-19 | 深圳市迪克曼科技开发有限公司 | Organic acid salt of nicotinamide ribose, composition and preparation method thereof |
US20210353656A1 (en) * | 2020-05-12 | 2021-11-18 | Nuvamid Sa | Combination of nicotinamide mononucleotide derivatives and histamine h2 receptor antagonists for viral infections |
EP3949964A1 (en) * | 2020-08-06 | 2022-02-09 | Nuvamid SA | Combination of nicotinamide mononucleotide derivatives and other therapeutic agents for use in the treatment of viral infections |
WO2022029275A1 (en) * | 2020-08-06 | 2022-02-10 | Nuvamid Sa | Combination of nicotinamide mononucleotide derivatives and other therapeutic agents for use in the treatment of coronavirus infections and covid-19 |
CN112500445B (en) * | 2020-12-04 | 2022-11-29 | 黄冈鲁班药业股份有限公司 | Preparation method of beta-nicotinamide ribose |
CN113274363B (en) * | 2021-04-29 | 2023-02-10 | 珠海润都制药股份有限公司 | Indapamide preparation |
EP4329753A1 (en) | 2021-04-30 | 2024-03-06 | Perfuse Therapeutics, Inc. | Pharmaceutical compositions and intravitreal drug delivery systems for the treatment of ocular diseases |
WO2022266322A1 (en) * | 2021-06-18 | 2022-12-22 | Mitopower Llc | Treatment of immune-related disorders, kidney disorders, liver disorders, hemolytic disorders, and oxidative stress-associated disorders using nrh, narh and reduced derivatives thereof |
WO2022269064A1 (en) * | 2021-06-24 | 2022-12-29 | Vestlandets Innovasjonsselskap As (Vis) | Nad-augmentation therapy for parkinson's disease |
WO2023102344A1 (en) * | 2021-12-01 | 2023-06-08 | University Of Florida Research Foundation, Incorporated | Combinatorial therapeutic approach for friedreich's ataxia |
CN115232184A (en) * | 2021-12-06 | 2022-10-25 | 宁波熙健医药科技有限公司 | Ribofuranosyl pyridine derivative, and pharmaceutical composition and use thereof |
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-
2018
- 2018-06-19 SG SG11201912267SA patent/SG11201912267SA/en unknown
- 2018-06-19 WO PCT/US2018/038201 patent/WO2018236814A2/en unknown
- 2018-06-19 US US16/012,004 patent/US11286274B2/en active Active
- 2018-06-19 EP EP18740009.8A patent/EP3642214A2/en active Pending
Also Published As
Publication number | Publication date |
---|---|
WO2018236814A3 (en) | 2019-02-07 |
US20180362570A1 (en) | 2018-12-20 |
EP3642214A2 (en) | 2020-04-29 |
US11286274B2 (en) | 2022-03-29 |
WO2018236814A2 (en) | 2018-12-27 |
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