SG11201909812VA - Heterocyclic compound - Google Patents

Heterocyclic compound

Info

Publication number
SG11201909812VA
SG11201909812VA SG11201909812VA SG11201909812VA SG 11201909812V A SG11201909812V A SG 11201909812VA SG 11201909812V A SG11201909812V A SG 11201909812VA SG 11201909812V A SG11201909812V A SG 11201909812VA
Authority
SG
Singapore
Prior art keywords
heterocyclic compound
calcium
expected
salt
useful
Prior art date
Application number
Inventor
Shuji Kitamura
Zenichi Ikeda
Sachie Morimoto
Minoru Ikoma
Koji Watanabe
Hideki Hirose
Takafumi Yukawa
Kenjiro Sato
Original Assignee
Takeda Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceuticals Co filed Critical Takeda Pharmaceuticals Co
Publication of SG11201909812VA publication Critical patent/SG11201909812VA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Abstract

Heterocyclic compound The present invention provides a compound or a salt thereof having a calcium-sensing receptor antagonistic activity, and being expected to be useful as an agent for preventing or treating heart failure, pulmonary hypertension, or the like. The compounds represented by formula (I) or a salt thereof has a calcium-sensing receptor antagonistic activity, and is expected to be useful as an agent for preventing or treating heart failure, pulmonary hypertension, or the like, wherein each symbol is as described in the specification. [No suitable figure]
SG11201909812V 2017-04-27 2018-04-26 Heterocyclic compound SG11201909812VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2017087959 2017-04-27
PCT/JP2018/016995 WO2018199235A1 (en) 2017-04-27 2018-04-26 Heterocyclic compound

Publications (1)

Publication Number Publication Date
SG11201909812VA true SG11201909812VA (en) 2019-11-28

Family

ID=63919858

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201909812V SG11201909812VA (en) 2017-04-27 2018-04-26 Heterocyclic compound

Country Status (14)

Country Link
US (1) US10919891B2 (en)
EP (1) EP3617209A4 (en)
JP (1) JP7177042B2 (en)
CN (1) CN110573512B (en)
AU (1) AU2018257331B2 (en)
BR (1) BR112019022465A2 (en)
CA (1) CA3061600A1 (en)
CO (1) CO2019012270A2 (en)
IL (1) IL270155B (en)
MX (1) MX2019012808A (en)
RU (1) RU2768473C2 (en)
SG (1) SG11201909812VA (en)
WO (1) WO2018199235A1 (en)
ZA (1) ZA201907792B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DOP2021000224A (en) * 2019-05-01 2021-12-15

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA03008291A (en) * 2001-03-14 2003-12-11 Gr Nenthal Gmbh Substituted pyrazolopyrimidines and thiazolopyrimidines.
CA2494700C (en) 2002-08-26 2011-06-28 Takeda Pharmaceutical Company Limited Calcium receptor modulating compound and use thereof
CN1771231B (en) 2002-08-26 2011-05-25 武田药品工业株式会社 Calcium receptor modulating compound and use thereof
US7205322B2 (en) 2003-02-12 2007-04-17 Bristol-Myers Squibb Company Thiazolidine compounds as calcium sensing receptor modulators
US7501405B2 (en) * 2003-04-11 2009-03-10 High Point Pharmaceuticals, Llc Combination therapy using an 11β-hydroxysteroid dehydrogenase type 1 inhibitor and an antihypertensive agent for the treatment of metabolic syndrome and related diseases and disorders
JP2005239611A (en) 2004-02-25 2005-09-08 Takeda Chem Ind Ltd Pyrazolopyrimidine derivative and its application
US20090304821A1 (en) 2006-03-08 2009-12-10 Takeda Pharmaceutical Company Limited Pharmaceutical Combination
JP6126135B2 (en) * 2012-02-03 2017-05-10 サノフイ Condensed pyrrole carboxamide and its use as a medicament
US9296746B2 (en) 2012-10-16 2016-03-29 Takeda Pharmaceutical Company Limited Heterocyclic compound
CN104910118B (en) 2014-03-13 2017-07-04 中国科学院上海药物研究所 One marcumar class compound and its production and use
JP6839097B2 (en) 2015-12-25 2021-03-03 武田薬品工業株式会社 Medicine
CA3019091C (en) 2016-03-28 2024-01-02 Takeda Pharmaceutical Company Limited Medicament

Also Published As

Publication number Publication date
CO2019012270A2 (en) 2020-02-28
CA3061600A1 (en) 2019-10-25
RU2019138175A3 (en) 2021-06-10
IL270155B (en) 2022-07-01
ZA201907792B (en) 2022-03-30
JPWO2018199235A1 (en) 2020-03-12
BR112019022465A2 (en) 2020-05-12
JP7177042B2 (en) 2022-11-22
WO2018199235A1 (en) 2018-11-01
IL270155A (en) 2019-12-31
AU2018257331B2 (en) 2022-04-07
US10919891B2 (en) 2021-02-16
EP3617209A4 (en) 2020-08-26
CN110573512A (en) 2019-12-13
RU2768473C2 (en) 2022-03-24
EP3617209A1 (en) 2020-03-04
AU2018257331A1 (en) 2019-11-14
CN110573512B (en) 2022-09-06
US20200131174A1 (en) 2020-04-30
RU2019138175A (en) 2021-05-27
MX2019012808A (en) 2022-02-21

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