SG11201903405UA - High resolution systems, kits, apparatus, and methods for screening microorganisms and other high throughput microbiology applications - Google Patents

High resolution systems, kits, apparatus, and methods for screening microorganisms and other high throughput microbiology applications

Info

Publication number
SG11201903405UA
SG11201903405UA SG11201903405UA SG11201903405UA SG11201903405UA SG 11201903405U A SG11201903405U A SG 11201903405UA SG 11201903405U A SG11201903405U A SG 11201903405UA SG 11201903405U A SG11201903405U A SG 11201903405UA SG 11201903405U A SG11201903405U A SG 11201903405UA
Authority
SG
Singapore
Prior art keywords
international
california
screening
methods
pct
Prior art date
Application number
SG11201903405UA
Inventor
Alexander Hallock
Kimberly WEMMER
Original Assignee
Gen Automation Lab Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Automation Lab Tech Inc filed Critical Gen Automation Lab Tech Inc
Publication of SG11201903405UA publication Critical patent/SG11201903405UA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -,` Organization MD HIM 01E101011M 3E1 0 III11101111 100 HOE NH ill OEN International Bureau (10) International Publication Number 3 (43) International Publication Date .....••'' WO 2018/075701 Al 26 April 2018 (26.04.2018) WIP0 I PCT (51) International Patent Classification: Kimberly; 29 Fleetwood Drive, Daly City, California C12M 1/04 (2006.01) C12Q 1/00 (2006.01) 94015 (US). C12M 1/34 (2006.01) C12Q 1/68 (2018.01) (74) Agent: SUN-HOFFMAN, Lin; P.O. Box 52048, Palo Alto, (21) International Application Number: California 94303 (US). PCT/US2017/057279 (81) Designated States (unless otherwise indicated, for every (22) International Filing Date: kind of national protection available): AE, AG, AL, AM, 19 October 2017 (19.10.2017) AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, (25) Filing Language: English DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, (26) Publication Language: English HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, (30) Priority Data: KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, 62/410,337 19 October 2016 (19.10.2016) US MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, (63) Related by continuation (CON) or continuation-in-part SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, (CIP) to earlier application: TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. US 15135377 (CIP) (84) Designated States (unless otherwise indicated, for every Filed on 21 April 2016 (21.04.2016) kind of regional protection available): ARIPO (BW, GH, — (71) Applicant: GENERAL AUTOMATION LAB TECH- GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, NOLOGIES, INC. [US/US]; 953 Indiana Street, Suite 372, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, San Francisco, California 94107 (US). TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, Inventors: HALLOCK, Alexander; 105 Camellia Av- (72) MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, enue, Redwood City, California 94061 (US). WEMMER, = (54) Title: HIGH RESOLUTION SYSTEMS, KITS, APPARATUS, AND METHODS FOR SCREENING MICROORGANISMS OTHER HIGH THROUGHPUT MICROBIOLOGY APPLICATIONS AND = = = = = ,-- .., -____ _ = /1117 • 0 illii _ • C:ZZz:22, 00,,,,, ologal oop l gittar • c o „,,, o 0474:7 _ --:: ,.' PoogPa ' ,';' ,Pz 112,2 7§7 27 •egrdiegeg ;.- 0 0 , 76 -811 gaboaggicti • • fapszt, ~ O poo 0 0 p0 ho sze o f = = = = _ = _ • -•, Il - ---- ,-• Il 0 N FIG. 1 11 in N © --- -- GO (57) : A microfabricated device defining a high density array of microwells is described for cultivating cells from a sample. ,-1 The device may be incubated to grow a plurality of cells, which may be split into an analysis portion and a reserve portion. Methods are 0 provided for screening a biological entity of interest using the microfabricated device, for example, for screening phosphate solubilizing \" bacteria or other bacteria producing acids. [Continued on next page] WO 2018/075701 Al MIDEDIMOM0101011EFIDINIIHIEDOEDIROIIMOVOIMIE TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) — with sequence listing part of description (Rule 5.2(a))
SG11201903405UA 2016-10-19 2017-10-19 High resolution systems, kits, apparatus, and methods for screening microorganisms and other high throughput microbiology applications SG11201903405UA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662410337P 2016-10-19 2016-10-19
PCT/US2017/057279 WO2018075701A1 (en) 2016-10-19 2017-10-19 High resolution systems, kits, apparatus, and methods for screening microorganisms and other high throughput microbiology applications

Publications (1)

Publication Number Publication Date
SG11201903405UA true SG11201903405UA (en) 2019-05-30

Family

ID=62019011

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201903405UA SG11201903405UA (en) 2016-10-19 2017-10-19 High resolution systems, kits, apparatus, and methods for screening microorganisms and other high throughput microbiology applications

Country Status (8)

Country Link
EP (1) EP3532600A4 (en)
JP (1) JP2019535245A (en)
CN (1) CN110168069A (en)
AU (1) AU2017345402A1 (en)
CA (1) CA3041109A1 (en)
IL (1) IL266043A (en)
SG (1) SG11201903405UA (en)
WO (1) WO2018075701A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112813014A (en) * 2019-11-15 2021-05-18 洛阳华清天木生物科技有限公司 Strain domestication and screening method based on microfluidic technology
JP2023106932A (en) * 2022-01-21 2023-08-02 国立大学法人東北大学 Collecting device, scanning ion conductance microscope provided with the same, and collecting method

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050070005A1 (en) * 1997-06-16 2005-03-31 Martin Keller High throughput or capillary-based screening for a bioactivity or biomolecule
US5858770A (en) * 1997-09-30 1999-01-12 Brandeis University Cell culture plate with oxygen and carbon dioxide-permeable waterproof sealing membrane
US6638730B2 (en) * 2001-03-06 2003-10-28 Council Of Scientific & Industrial Research Composition for qualitative screening of phosphate solubilizing microorganisms and a qualitative method for screening microorganisms
EP1373481A4 (en) * 2001-03-07 2005-04-13 Xenogen Corp Methods of screening for introduction of dna into a target cell
US20070072187A1 (en) * 2003-11-28 2007-03-29 Blok Herman J Novel methods and apparatus for cell based microarray assays
AU2008245696B2 (en) * 2007-04-27 2013-11-07 Pelican Technology Holdings, Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
WO2008157382A1 (en) * 2007-06-15 2008-12-24 Wyeth Methods for measuring ph in a small-scale cell culture system and predicting performance of cells in a large-scale culture system
KR101679869B1 (en) * 2008-04-05 2016-11-25 싱글 셀 테크놀로지, 아이엔씨. Method of screening single cells for the production of biologically active agents
DK2297333T3 (en) * 2008-05-30 2015-04-07 Massachusetts Inst Technology Method for spatial separation and for screening cells
EP2154239A1 (en) * 2008-08-14 2010-02-17 Bio-Iliberis Research and Development S.L. Microorganism capable of solubilizing phosphate and iron and its applications
EP2350320A4 (en) * 2008-11-12 2012-11-14 Caris Life Sciences Luxembourg Holdings Methods and systems of using exosomes for determining phenotypes
US9244071B2 (en) * 2009-01-21 2016-01-26 Massachusetts Institute Of Technology Compositions and methods for assessing cytotoxicity of single cells
JP4674337B2 (en) * 2009-03-10 2011-04-20 国立大学法人 岡山大学 Cell observation device and cell observation method
US9234229B2 (en) * 2009-12-08 2016-01-12 The Board Of Trustees Of The Leland Stanford Junior University High throughput system for isolation, growth, and detection of lipid inclusions in bacteria
SG194785A1 (en) * 2011-05-13 2013-12-30 Amyris Inc Methods and compositions for detecting microbial production of water-immiscible compounds
US20150118707A1 (en) * 2013-10-25 2015-04-30 Ponnambalam Selvaganapathy Method and device for detecting metabollically active cells
JP2016146752A (en) * 2015-01-23 2016-08-18 株式会社イッコーズ High content analysis and generation method of three-dimensional cell cultivation model under high respiration environment for screening
WO2016172362A1 (en) * 2015-04-21 2016-10-27 General Automation Lab Technologies, Inc. High resolution systems, kits, apparatus, and methods for high throughput microbiology applications

Also Published As

Publication number Publication date
CA3041109A1 (en) 2018-04-26
EP3532600A1 (en) 2019-09-04
CN110168069A (en) 2019-08-23
IL266043A (en) 2019-06-30
JP2019535245A (en) 2019-12-12
WO2018075701A1 (en) 2018-04-26
EP3532600A4 (en) 2020-09-16
AU2017345402A1 (en) 2019-05-23

Similar Documents

Publication Publication Date Title
SG11201807487WA (en) Generation of midbrain-specific organoids from human pluripotent stem cells
SG11201804563SA (en) Digital microfluidic system for single-cell isolation and characterization of analytes
SG11201900907YA (en) Adenosine nucleobase editors and uses thereof
SG11201903519UA (en) Methods and systems for barcoding nucleic acid molecules from individual cells or cell populations
SG11201805680SA (en) Methods and compositions for the treatment of neurologic disease
SG11201809005TA (en) Plasma-based detection of anaplastic lymphoma kinase (alk) nucleic acids and alk fusion transcripts and uses thereof in diagnosis and treatment of cancer
SG11201811640SA (en) Multispecific antigen binding proteins and methods of use thereof
SG11201809913PA (en) Methods for detecting target nucleic acids in a sample
SG11201908337VA (en) Stimulatory cell lines for ex vivo expansion and activation of natural killer cells
SG11201803958WA (en) Nucleic acids encoding repetitive amino acid sequences rich in proline and alanine residues that have low repetitive nucleotide sequences
SG11201810003UA (en) Using programmable dna binding proteins to enhance targeted genome modification
SG11201907764PA (en) Methods for screening infections
SG11201811048UA (en) Single-cell transcript sequencing
SG11201806284TA (en) Low pressure separator having an internal divider and uses therefor
SG11201906341XA (en) Improved serum albumin binders
SG11201811159SA (en) Methods for multi-resolution analysis of cell-free nucleic acids
SG11201809349SA (en) System and method for in-line monitoring of airborne contamination and process health
SG11201408153YA (en) Prostate-specific membrane antigen antibody drug conjugates
SG11201901822QA (en) Single cell analysis of transposase accessible chromatin
SG11201807881VA (en) Compositions and methods for making antibodies based on use of an expression-enhancing locus
SG11201809789SA (en) Dna monoclonal antibodies targeting checkpoint molecules
SG11201906717SA (en) Methods and systems for associating physical and genetic properties of biological particles
SG11201809594WA (en) Nicotine particles and compositions
SG11201906225PA (en) Maintenance and expansion of pancreatic progenitor cells
SG11201900231RA (en) Culture media for culturing pluripotent stem cells in suspension