SG11201809558PA - Anti-human hemoglobin monoclonal antibody or antibody kit, insoluble carrier particle to which anti-human hemoglobin monoclonal antibody is immobilized, and measurement reagent and measurement method using same - Google Patents

Anti-human hemoglobin monoclonal antibody or antibody kit, insoluble carrier particle to which anti-human hemoglobin monoclonal antibody is immobilized, and measurement reagent and measurement method using same

Info

Publication number
SG11201809558PA
SG11201809558PA SG11201809558PA SG11201809558PA SG11201809558PA SG 11201809558P A SG11201809558P A SG 11201809558PA SG 11201809558P A SG11201809558P A SG 11201809558PA SG 11201809558P A SG11201809558P A SG 11201809558PA SG 11201809558P A SG11201809558P A SG 11201809558PA
Authority
SG
Singapore
Prior art keywords
monoclonal antibody
human hemoglobin
antibody
hemoglobin monoclonal
immobilized
Prior art date
Application number
SG11201809558PA
Inventor
Ryota Yasui
Megumi YUI
Mitsuru MAKINODAN
Yasuhiro Seki
Chisa Sakanishi
Original Assignee
Eiken Chemical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eiken Chemical filed Critical Eiken Chemical
Publication of SG11201809558PA publication Critical patent/SG11201809558PA/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57419—Specifically defined cancers of colon
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/545—Synthetic resin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/545—Synthetic resin
    • G01N33/546—Synthetic resin as water suspendable particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/553—Metal or metal coated
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721—Haemoglobin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

ANTIHUMAN HEMOGLOBIN MONOCLONAL ANTIBODY OR ANTIBODY KIT, INSOLUBLE CARRIER PARTICLE TO WHICH ANTI-HUMAN HEMOGLOBIN MONOCLONAL ANTIBODY IS IMMOBILIZED, AND MEASUREMENT REAGENT AND MEASUREMENT METHOD USING SAME The present invention has an object to provide an anti-human hemoglobin monoclonal antibody or an antibody kit for specifically 10 detecting and measuring a hemoglobin-haptoglobin complex in a sample with ease, and an insoluble carrier particle to which the monoclonal antibody is immobilized, and a measurement reagent and a measurement method for specifically detecting and measuring a hemoglobin-haptoglobin complex in a sample using the same. The 15 anti-human hemoglobin monoclonal antibody of the present invention does not react to free hemoglobin or free haptoglobin which is not forming a complex but specifically reacts to a hemoglobin-haptoglobin complex, when the antibody is immobilized to the insoluble carrier particle and used. 20 NIL 36
SG11201809558PA 2016-05-30 2017-05-26 Anti-human hemoglobin monoclonal antibody or antibody kit, insoluble carrier particle to which anti-human hemoglobin monoclonal antibody is immobilized, and measurement reagent and measurement method using same SG11201809558PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2016107343 2016-05-30
PCT/JP2017/019736 WO2017209001A1 (en) 2016-05-30 2017-05-26 Anti-human hemoglobin monoclonal antibody or antibody kit, insoluble carrier particle to which anti-human hemoglobin monoclonal antibody is immobilized, and measurement reagent and measurement method using same

Publications (1)

Publication Number Publication Date
SG11201809558PA true SG11201809558PA (en) 2018-12-28

Family

ID=60477766

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201809558PA SG11201809558PA (en) 2016-05-30 2017-05-26 Anti-human hemoglobin monoclonal antibody or antibody kit, insoluble carrier particle to which anti-human hemoglobin monoclonal antibody is immobilized, and measurement reagent and measurement method using same

Country Status (9)

Country Link
US (1) US11175292B2 (en)
EP (1) EP3467498A4 (en)
JP (2) JP6991968B2 (en)
KR (1) KR102433648B1 (en)
CN (1) CN110383067B (en)
AU (1) AU2017275081B2 (en)
SG (1) SG11201809558PA (en)
TW (1) TWI800483B (en)
WO (1) WO2017209001A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20210064272A (en) * 2018-09-26 2021-06-02 에이껜 가가꾸 가부시끼가이샤 Hemoglobin measurement reagent, measurement kit and measurement method
CN112979799B (en) * 2019-12-18 2022-11-08 东莞市朋志生物科技有限公司 Binding protein containing hemoglobin antigen structural domain
CN111057150B (en) * 2019-12-30 2021-10-29 深圳开立生物医疗科技股份有限公司 Latex microsphere, application thereof and glycosylated hemoglobin detection kit
CN114478759A (en) * 2020-11-12 2022-05-13 东莞市朋志生物科技有限公司 Anti-human hemoglobin antibody, application thereof and diagnostic kit

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61137064A (en) 1984-12-07 1986-06-24 Fujirebio Inc Method for preparatory screening of colon cancer
JPH02193071A (en) 1989-01-20 1990-07-30 Green Cross Corp:The Kit of reagent for measuring haptoglobin-hemoglobin complex and measuring method of haptoglobin-hemoglobin complex using the same
JPH05322888A (en) 1992-05-18 1993-12-07 Toyobo Co Ltd Method and kit for determining free hemoglobin
US5552295A (en) * 1994-03-02 1996-09-03 The United States Of America As Represented By The Secretary Of Agriculture Monoclonal antibodies to bovine haptoglobin and methods for detecting serum haptoglobin levels
JP4926320B2 (en) * 1999-04-28 2012-05-09 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム Compositions and methods for cancer treatment by selective inhibition of VEGF
TWI235159B (en) 1999-06-30 2005-07-01 Dev Center Biotechnology Anti-human hemoglobin monoclonal antibodies for detecting fecal occult blood, producing hybridomas and uses thereof
JP2001221800A (en) 2000-02-14 2001-08-17 Internatl Reagents Corp Measurement method for complex
JP4390963B2 (en) 2000-04-05 2009-12-24 シスメックス株式会社 Immunoassay method and reagent kit
EP1314982B1 (en) * 2000-08-29 2009-07-29 Kyowa Medex Co., Ltd. Highly reproducible agglutination immunoassay method and reagents
US20080227208A1 (en) * 2007-03-16 2008-09-18 Hsiao-Ching Yee Devices and Methods for Detection of Occult Blood
WO2009065551A1 (en) 2007-11-20 2009-05-28 Roche Diagnostics Gmbh Method of assessing colorectal cancer from a stool sample by use of the marker combination calprotectin and hemoglobin/haptoglobin complex
CN101236210A (en) * 2008-01-29 2008-08-06 王学生 Rapid joint inspection reagent for hemoglobin -haptoglobin complex and occult blood in stool
JP5191291B2 (en) 2008-07-04 2013-05-08 和光純薬工業株式会社 Method and reagent kit for measuring hemoglobin in stool specimen
JP5085736B2 (en) 2008-07-31 2012-11-28 日東紡績株式会社 Method for measuring complex and kit used therefor
DE102012013888A1 (en) * 2012-07-09 2014-05-22 Schebo Biotech Ag Test kit (combi rapid test) for the synchronous detection of biomarkers in stool for the detection of pathological changes in the gastrointestinal tract, especially in the intestine
CN104515859A (en) * 2014-12-17 2015-04-15 杭州慧缘泰医疗器械有限公司 Hemoglobin, hemoglobin-haptoglobin composite and transferrin joint examination kit and preparation method and detection method thereof

Also Published As

Publication number Publication date
US20200319183A1 (en) 2020-10-08
EP3467498A4 (en) 2019-11-13
AU2017275081A2 (en) 2019-01-17
JP6991968B2 (en) 2022-01-13
AU2017275081A1 (en) 2019-01-03
TW201802472A (en) 2018-01-16
JPWO2017209001A1 (en) 2019-03-28
KR102433648B1 (en) 2022-08-17
CN110383067A (en) 2019-10-25
KR20190015338A (en) 2019-02-13
WO2017209001A1 (en) 2017-12-07
JP2022033935A (en) 2022-03-02
CN110383067B (en) 2023-07-21
JP7386220B2 (en) 2023-11-24
TWI800483B (en) 2023-05-01
EP3467498A1 (en) 2019-04-10
US11175292B2 (en) 2021-11-16
AU2017275081B2 (en) 2023-12-07

Similar Documents

Publication Publication Date Title
SG11201809558PA (en) Anti-human hemoglobin monoclonal antibody or antibody kit, insoluble carrier particle to which anti-human hemoglobin monoclonal antibody is immobilized, and measurement reagent and measurement method using same
MX2020009021A (en) Assays for detecting the presence or amount of an anti-drug antibody.
PH12018500558B1 (en) Device and system for analyzing a sample, particularly blood, as well as methods of using the same
PH12018500302A1 (en) Bio/chemical assay devices and methods for simplified steps, small samples, accelerated speed, and ease-of-use
MX362075B (en) Hcv antigen-antibody combination assay and methods and compositions for use therein.
NZ728582A (en) Instrument for analyzing biological samples and reagents
PH12019502558A1 (en) Diagnostic assays for detecting, quantifying, and/or tracking microbes and other analytes
MX2016001573A (en) Assays for timp2 having improved performance in biological samples.
ZA202002415B (en) Detection of symmetrical dimethylarginine
BR112012025082A8 (en) NEW MONOCLONAL ANTIBODIES AND D-DIMER IMMUNOLOGICAL ANALYSIS METHOD
WO2016025382A3 (en) Probes for quantitative imaging of thiols in various environments
MX2021005902A (en) Cell-based method for determining botulinum toxin activity.
MX347002B (en) Psa assay method and reagent therefor.
MX2015004419A (en) Detecting an analyte and determining the concentration of an analyte using magnetizable beads.
EA201400571A1 (en) SPECIFIC TO TRANSRESVEROTROL ANTIBODIES AND THEIR APPLICATION
MX2019011702A (en) Improved immunogenicity assays.
EP3508849A4 (en) Antibody measurement method using antigen-carrying insoluble carrier particles on which antigen is immobilized by different methods, and reagent for antibody measurement
NZ720608A (en) Β-glucan assay methods
WO2016071698A3 (en) A test device and method of using a test device
JP2017526931A5 (en)
MY194325A (en) Test object detection method, and immunoassay instrument and monoclonal antibody for same
GB2521885A8 (en) An immunoassay detection device
MX2023007281A (en) Methods for the detection of anti-drug antibodies against factor xi and/or factor xia antibodies.
GB2547600A (en) Devices and methods for detecting norovirus on surfaces
WO2018226098A3 (en) Methods for typing neurological disorders and cancer, and devices for use therein