SG11201809252YA - Methods for determining dpp3 and therapeutic methods - Google Patents

Methods for determining dpp3 and therapeutic methods

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Publication number
SG11201809252YA
SG11201809252YA SG11201809252YA SG11201809252YA SG11201809252YA SG 11201809252Y A SG11201809252Y A SG 11201809252YA SG 11201809252Y A SG11201809252Y A SG 11201809252YA SG 11201809252Y A SG11201809252Y A SG 11201809252YA SG 11201809252Y A SG11201809252Y A SG 11201809252YA
Authority
SG
Singapore
Prior art keywords
international
methods
pct
dpp3
determining
Prior art date
Application number
SG11201809252YA
Inventor
Dr Andreas Bergmann
Original Assignee
Sphingotec Therapeutics Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sphingotec Therapeutics Gmbh filed Critical Sphingotec Therapeutics Gmbh
Publication of SG11201809252YA publication Critical patent/SG11201809252YA/en

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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/581—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
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    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
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    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
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Abstract

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property 1111111111 0111010101111101011111011101111101011111111111101111111011110111111 Organization International Bureau (10) International Publication Number (43) International Publication Date .....0\"\"\" WO 2017/182561 Al 26 October 2017 (26.10.2017) WIPO I PCT (51) International Patent Classification: KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, G01N 33/68 (2006.01) A61K 39/395 (2006.01) MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, GO1N 33/574 (2006.01) PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, (21) International Application Number: SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, PCT/EP2017/059377 TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (22) International Filing Date: (84) Designated States (unless otherwise indicated, for every 20 April 2017 (20.04.2017) kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, (25) Filing Language: English UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, (26) Publication Language: English TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, (30) Priority Data: MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, 16166476.8 21 April 2016 (21.04.2016) EP TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). (71) Applicant: SPHINGOTEC THERAPEUTICS GMBH [DE/DE]; Neuendorfstrasse 15A, 16761 Hennigsdorf (DE). Published: (72) Inventor: BERGMANN, Dr. Andreas; Am Rosenanger — with international search report (Art. 21(3)) 78, 13465 Berlin (DE). — with amended claims (Art. 19(1)) — with sequence listing part of description (Rule 5.2(a)) (74) Agent: BOEHMERT & BOEHMERT; Dr. Ute Kilger, Hollerallee 32, 28209 Bremen (DE). = (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, =_ AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, = DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, = HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, (54) Title: = Mg. 2 A: = 55- = - = 45- = = 40 = = 35 E = •D o n. 26- li 20 • li V; N ot 1-1 IN li 5 METHODS FOR DETERMINING DPP3 AND THERAPEUTIC METHODS ocu . * . . . . . ] p ‹ 0.005 (57) : The present invention is directed to methods for determining active DPP3 in a bodily fluid sample, an assay or kit for determining active DPP3 in a bodily fluid sample, a method for diagnosing a disease or condition in a subject accompanied by or related to necrotic processes and methods of treating or pre- venting said disease. © Norm F MI Sepsis Cancer AKI LRTI N C
SG11201809252YA 2016-04-21 2017-04-20 Methods for determining dpp3 and therapeutic methods SG11201809252YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16166476 2016-04-21
PCT/EP2017/059377 WO2017182561A1 (en) 2016-04-21 2017-04-20 Methods for determining dpp3 and therapeutic methods

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SG11201809252YA true SG11201809252YA (en) 2018-11-29

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US (2) US20190145981A1 (en)
EP (3) EP3896450A1 (en)
JP (3) JP2019520550A (en)
KR (2) KR20230123520A (en)
CN (1) CN110168372A (en)
AU (2) AU2017252212B2 (en)
BR (1) BR112018071583A2 (en)
CA (1) CA3021252A1 (en)
CH (1) CH713803B1 (en)
DE (1) DE112017002105T5 (en)
IL (1) IL262472A (en)
MX (2) MX2018012856A (en)
SG (1) SG11201809252YA (en)
WO (1) WO2017182561A1 (en)

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CA3080251A1 (en) * 2017-10-25 2019-05-02 4TEEN4 Pharmaceuticals GmbH Dpp3 binder directed to and binding to specific dpp3-epitopes and its use in the prevention or treatment of diseases / acute conditions that are associated with oxidative stress
WO2020128039A2 (en) * 2018-12-21 2020-06-25 4TEEN4 Pharmaceuticals GmbH Therapy guidance and/or therapy monitoring for a treatment with angiotensin-receptor-agonist and/or a precursor thereof
BR112022016843A2 (en) 2020-02-27 2022-10-11 Adrenomed Ag ANTIADRENOMEDULIN BINDING (ADM) FOR USE IN SHOCK PATIENTS THERAPY
AU2021228207A1 (en) 2020-02-27 2022-10-20 4TEEN4 Pharmaceuticals GmbH DPP3 for therapy guidance, monitoring and stratification of nt-ADM antibodies in patients with shock
MX2022010207A (en) 2020-02-27 2022-11-16 Adrenomed Ag Anti-adrenomedullin (adm) antibody or anti-adm antibody fragment or anti-adm non-ig scaffold for use in therapy or prevention of shock.
EP3922993A1 (en) 2020-06-12 2021-12-15 4TEEN4 Pharmaceuticals GmbH Dpp3 in patients infected with coronavirus
AU2021237689A1 (en) 2020-03-16 2022-11-03 4TEEN4 Pharmaceuticals GmbH DPP3 in patients infected with coronavirus
WO2023175035A1 (en) 2022-03-15 2023-09-21 Adrenomed Ag Stable aqueous formulation of an anti-adrenomedullin (adm) antibody or anti-adm antibody fragment
CN117186177A (en) * 2022-05-31 2023-12-08 中国农业大学 Duck blood cell protein peptide with uric acid reducing activity and preparation method thereof
WO2024023368A1 (en) 2022-07-29 2024-02-01 4TEEN4 Pharmaceuticals GmbH Prediction of an increase of dpp3 in a patient with septic shock
WO2024023369A1 (en) 2022-07-29 2024-02-01 Adrenomed Ag Anti-adrenomedullin (adm) antibody or anti-adm antibody fragment or anti-adm non-ig scaffold for use in therapy or prevention of shock

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