SG11201806168PA - Endothelin-1 receptor based endothelin-1 sponge - Google Patents

Endothelin-1 receptor based endothelin-1 sponge

Info

Publication number
SG11201806168PA
SG11201806168PA SG11201806168PA SG11201806168PA SG11201806168PA SG 11201806168P A SG11201806168P A SG 11201806168PA SG 11201806168P A SG11201806168P A SG 11201806168PA SG 11201806168P A SG11201806168P A SG 11201806168PA SG 11201806168P A SG11201806168P A SG 11201806168PA
Authority
SG
Singapore
Prior art keywords
endothelin
international
pct
sponge
fusion polypeptides
Prior art date
Application number
SG11201806168PA
Inventor
Arjun Jain
Original Assignee
Arjun Jain
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB201503453A external-priority patent/GB201503453D0/en
Application filed by Arjun Jain filed Critical Arjun Jain
Publication of SG11201806168PA publication Critical patent/SG11201806168PA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2318/00—Antibody mimetics or scaffolds
    • C07K2318/10—Immunoglobulin or domain(s) thereof as scaffolds for inserted non-Ig peptide sequences, e.g. for vaccination purposes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property -, Organization 11111111011110111010101111101111101011101110011111110011111001111101111011111 International Bureau 0.. .... .. ..... ...,/ (10) International Publication Number (43) International Publication Date WO 2016/139543 Al 9 September 2016 (09.09.2016) WIP0 I PCT (51) International Patent Classification: KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, C07K 14/72 (2006.01) MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, (21) International Application Number: SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, PCT/1B2016/050337 TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (22) International Filing Date: (84) Designated States (unless otherwise indicated, for every 22 January 2016 (22.01.2016) kind of regional protection available): ARIPO (BW, GH, (25) Filing Language: English GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, (26) Publication Language: English TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, (30) Priority Data: DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, 1503453.1 1 March 2015 (01.03.2015) GB LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, 1507043.6 24 April 2015 (24.04.2015) GB SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). (72) Inventor; and (71) Applicant : JAIN, Arjun [IN/IN]; C-1843 Palam Vihar, Declarations under Rule 4.17: Gurgaon 122017 (IN). — as to the identio. , of the inventor (Rule 4.17(i)) (81) Designated States (unless otherwise indicated, for every Published: kind of national protection available): AE, AG, AL, AM, — AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, with international search report (Art. 21(3)) BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, — with amended claims and statement (Art. 190)) DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, 1-1 M 7r kr) 0\ M Il --.... Il © (54) Title: ENDOTHELIN-1 RECEPTOR BASED ENDOTHELIN-1 SPONGE ei O (57) : Fusion polypeptides capable of binding endothelin-1 to form a non-functional complex are provided, including ,1 . amino acid sequences of the fusion polypeptides. The fusion polypeptides will be linked to the Fc portion of human IgG1 to form di - .,. mers that will function as endothelin-1 antagonists (endothelin-1 sponge).
SG11201806168PA 2015-03-01 2016-01-22 Endothelin-1 receptor based endothelin-1 sponge SG11201806168PA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB201503453A GB201503453D0 (en) 2015-03-01 2015-03-01 Endothelin-1"sponge"
GBGB1507043.6A GB201507043D0 (en) 2015-03-01 2015-04-24 Endothelin-1 receptor(s) based endothelin-1 sponge
PCT/IB2016/050337 WO2016139543A1 (en) 2015-03-01 2016-01-22 Endothelin-1 receptor based endothelin-1 sponge

Publications (1)

Publication Number Publication Date
SG11201806168PA true SG11201806168PA (en) 2018-08-30

Family

ID=63865744

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201806168PA SG11201806168PA (en) 2015-03-01 2016-01-22 Endothelin-1 receptor based endothelin-1 sponge

Country Status (4)

Country Link
AU (1) AU2016227458A1 (en)
CA (1) CA3011824A1 (en)
SG (1) SG11201806168PA (en)
WO (1) WO2016139543A1 (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6927044B2 (en) * 1998-09-25 2005-08-09 Regeneron Pharmaceuticals, Inc. IL-1 receptor based cytokine traps
WO2003092610A2 (en) * 2002-05-01 2003-11-13 Regeneron Pharmaceuticals, Inc. Methods of using cytokine antagonists to treat hiv infection and aids

Also Published As

Publication number Publication date
WO2016139543A1 (en) 2016-09-09
CA3011824A1 (en) 2016-09-09
AU2016227458A1 (en) 2018-08-02

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