SG11201800394WA - Novel endos mutant enzyme - Google Patents
Novel endos mutant enzymeInfo
- Publication number
- SG11201800394WA SG11201800394WA SG11201800394WA SG11201800394WA SG11201800394WA SG 11201800394W A SG11201800394W A SG 11201800394WA SG 11201800394W A SG11201800394W A SG 11201800394WA SG 11201800394W A SG11201800394W A SG 11201800394WA SG 11201800394W A SG11201800394W A SG 11201800394WA
- Authority
- SG
- Singapore
- Prior art keywords
- novel
- mutant enzyme
- endos mutant
- endos
- enzyme
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/02—Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01096—Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase (3.2.1.96)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2015141901 | 2015-07-16 | ||
| PCT/JP2016/070921 WO2017010559A1 (en) | 2015-07-16 | 2016-07-15 | Novel endos mutant enzyme |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201800394WA true SG11201800394WA (en) | 2018-02-27 |
Family
ID=57757160
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201914047RA SG10201914047RA (en) | 2015-07-16 | 2016-07-15 | Novel endos mutant enzyme |
| SG11201800394WA SG11201800394WA (en) | 2015-07-16 | 2016-07-15 | Novel endos mutant enzyme |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201914047RA SG10201914047RA (en) | 2015-07-16 | 2016-07-15 | Novel endos mutant enzyme |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US11001819B2 (en) |
| EP (1) | EP3323886B1 (en) |
| JP (1) | JP6752203B2 (en) |
| KR (1) | KR102546854B1 (en) |
| CN (1) | CN108026518B (en) |
| AU (1) | AU2016294206B9 (en) |
| ES (1) | ES2848861T3 (en) |
| HK (1) | HK1248271A1 (en) |
| SG (2) | SG10201914047RA (en) |
| TW (1) | TWI730972B (en) |
| WO (1) | WO2017010559A1 (en) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018532990A (en) | 2015-09-04 | 2018-11-08 | オービーアイ ファーマ，インコーポレイテッド | Glycan arrays and methods of use |
| CA3019560A1 (en) | 2016-03-29 | 2017-10-05 | Obi Pharma, Inc. | Antibodies, pharmaceutical compositions and methods |
| US10980894B2 (en) | 2016-03-29 | 2021-04-20 | Obi Pharma, Inc. | Antibodies, pharmaceutical compositions and methods |
| EP3445395A4 (en) | 2016-04-22 | 2019-12-25 | OBI Pharma, Inc. | Cancer immunotherapy by immune activation or immune modulation via globo series antigens |
| EP3480211A4 (en) | 2016-07-01 | 2019-12-25 | Daiichi Sankyo Company, Limited | Hanp-fc-containing molecular conjugate |
| EP3491026A4 (en) | 2016-07-29 | 2020-07-29 | OBI Pharma, Inc. | Human antibodies, pharmaceutical compositions and methods |
| ES2911522T3 (en) * | 2016-12-02 | 2022-05-19 | Daiichi Sankyo Co Ltd | Novel endo-ß-n-acetylglucosaminidase |
| US11628223B2 (en) | 2017-09-29 | 2023-04-18 | Daiichi Sankyo Company, Limited | Antibody-drug conjugates comprising substituted benzo[e]pyrrolo[1,2-α][1,4]diazepines |
| US11203645B2 (en) | 2018-06-27 | 2021-12-21 | Obi Pharma, Inc. | Glycosynthase variants for glycoprotein engineering and methods of use |
| JP7401456B2 (en) | 2018-11-14 | 2023-12-19 | 第一三共株式会社 | Anti-CDH6 antibody-pyrrolobenzodiazepine derivative conjugate |
| SG11202109860VA (en) | 2019-03-25 | 2021-10-28 | Daiichi Sankyo Co Ltd | Anti-her2 antibody-pyrrolobenzodiazepine derivative conjugate |
| CN113631229A (en) | 2019-03-25 | 2021-11-09 | 第一三共株式会社 | Antibody-pyrrolobenzodiazepine derivative conjugates |
| EP3949988A4 (en) | 2019-03-27 | 2022-11-16 | Daiichi Sankyo Company, Limited | Combination of antibody-pyrrolobenzodiazepine derivative conjugate and parp inhibitor |
| AU2020325204B2 (en) * | 2019-08-05 | 2024-01-04 | Cho Pharma, Inc. | Fusion protein for remodeling antibody glycoform |
| US20230039189A1 (en) | 2020-01-10 | 2023-02-09 | Riken | Population of antibodies comprising homogeneous antibodies each having left-right asymmetric sugar chains, and method for producing same |
| JP2023532219A (en) * | 2020-06-18 | 2023-07-27 | 上海宝済薬業有限公司 | Immunoglobulin degrading enzyme IdeE mutant |
| JPWO2022050300A1 (en) | 2020-09-02 | 2022-03-10 | ||
| WO2022211075A1 (en) * | 2021-03-31 | 2022-10-06 | 日本マイクロバイオファーマ株式会社 | Method for manufacturing antibody-drug conjugate and enzyme used for same |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5722627B2 (en) * | 2007-09-14 | 2015-05-27 | ジェノビス エービー | Methods and kits for dissociation of FC gamma receptor-IgG complex and purification and detection of IgG |
| WO2013012066A1 (en) * | 2011-07-21 | 2013-01-24 | 京セラ株式会社 | Lighting device, image sensor head and reading device provided with same |
| GB201201314D0 (en) * | 2012-01-26 | 2012-03-07 | Isis Innovation | Composition |
| CA2862925C (en) | 2012-02-10 | 2020-01-21 | University Of Maryland, Baltimore | Chemoenzymatic glycoengineering of antibodies and fc fragments thereof |
-
2016
- 2016-07-15 TW TW105122321A patent/TWI730972B/en active
- 2016-07-15 AU AU2016294206A patent/AU2016294206B9/en active Active
- 2016-07-15 KR KR1020187001358A patent/KR102546854B1/en active IP Right Grant
- 2016-07-15 SG SG10201914047RA patent/SG10201914047RA/en unknown
- 2016-07-15 CN CN201680041901.2A patent/CN108026518B/en active Active
- 2016-07-15 WO PCT/JP2016/070921 patent/WO2017010559A1/en active Application Filing
- 2016-07-15 JP JP2017528730A patent/JP6752203B2/en active Active
- 2016-07-15 ES ES16824539T patent/ES2848861T3/en active Active
- 2016-07-15 SG SG11201800394WA patent/SG11201800394WA/en unknown
- 2016-07-15 EP EP16824539.7A patent/EP3323886B1/en active Active
- 2016-07-15 US US15/745,357 patent/US11001819B2/en active Active
-
2018
- 2018-06-08 HK HK18107521.3A patent/HK1248271A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN108026518B (en) | 2022-09-06 |
| TWI730972B (en) | 2021-06-21 |
| JP6752203B2 (en) | 2020-09-09 |
| AU2016294206B9 (en) | 2021-12-23 |
| EP3323886A1 (en) | 2018-05-23 |
| HK1248271A1 (en) | 2018-10-12 |
| EP3323886B1 (en) | 2020-10-21 |
| SG10201914047RA (en) | 2020-03-30 |
| KR20180030536A (en) | 2018-03-23 |
| US11001819B2 (en) | 2021-05-11 |
| KR102546854B1 (en) | 2023-06-22 |
| TW201708540A (en) | 2017-03-01 |
| EP3323886A4 (en) | 2019-02-27 |
| US20180208915A1 (en) | 2018-07-26 |
| WO2017010559A1 (en) | 2017-01-19 |
| JPWO2017010559A1 (en) | 2018-04-26 |
| AU2016294206A1 (en) | 2018-02-08 |
| AU2016294206B2 (en) | 2021-12-02 |
| ES2848861T3 (en) | 2021-08-12 |
| CN108026518A (en) | 2018-05-11 |
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