SG11201709634QA - Nitrogen-containing tricyclic derivative having hiv replication inhibitory activity - Google Patents
Nitrogen-containing tricyclic derivative having hiv replication inhibitory activityInfo
- Publication number
- SG11201709634QA SG11201709634QA SG11201709634QA SG11201709634QA SG11201709634QA SG 11201709634Q A SG11201709634Q A SG 11201709634QA SG 11201709634Q A SG11201709634Q A SG 11201709634QA SG 11201709634Q A SG11201709634Q A SG 11201709634QA SG 11201709634Q A SG11201709634Q A SG 11201709634QA
- Authority
- SG
- Singapore
- Prior art keywords
- nitrogen
- inhibitory activity
- hiv replication
- tricyclic derivative
- containing tricyclic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/06—Peri-condensed systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2015109547 | 2015-05-29 | ||
| JP2015170222 | 2015-08-31 | ||
| JP2015223036 | 2015-11-13 | ||
| JP2016054215 | 2016-03-17 | ||
| PCT/JP2016/065702 WO2016194806A1 (en) | 2015-05-29 | 2016-05-27 | Nitrogen-containing tricyclic derivative having hiv replication inhibitory activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201709634QA true SG11201709634QA (en) | 2017-12-28 |
Family
ID=57442245
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201709634QA SG11201709634QA (en) | 2015-05-29 | 2016-05-27 | Nitrogen-containing tricyclic derivative having hiv replication inhibitory activity |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US10494380B2 (en) |
| EP (1) | EP3305789A4 (en) |
| JP (2) | JP6614585B2 (en) |
| KR (1) | KR20180011267A (en) |
| CN (2) | CN107922423B (en) |
| AU (1) | AU2016271762B2 (en) |
| BR (1) | BR112017025367A2 (en) |
| CA (1) | CA2987384A1 (en) |
| HK (1) | HK1253539A1 (en) |
| IL (1) | IL255580B (en) |
| MA (1) | MA43120A (en) |
| MX (1) | MX2017015256A (en) |
| RU (1) | RU2720145C2 (en) |
| SG (1) | SG11201709634QA (en) |
| TW (1) | TWI700284B (en) |
| WO (1) | WO2016194806A1 (en) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112015022942B1 (en) | 2013-03-15 | 2022-02-22 | Incyte Holdings Corporation | Tricyclic heterocycle compounds, method for inhibiting bet protein in vitro and pharmaceutical composition comprising said compounds |
| JP2016523964A (en) | 2013-07-08 | 2016-08-12 | インサイト・ホールディングス・コーポレイションＩｎｃｙｔｅ Ｈｏｌｄｉｎｇｓ Ｃｏｒｐｏｒａｔｉｏｎ | Tricyclic heterocycles as BET protein inhibitors |
| WO2015081203A1 (en) | 2013-11-26 | 2015-06-04 | Incyte Corporation | Bicyclic heterocycles as bet protein inhibitors |
| WO2015095492A1 (en) | 2013-12-19 | 2015-06-25 | Incyte Corporation | Tricyclic heterocycles as bet protein inhibitors |
| NZ763740A (en) | 2014-04-23 | 2023-06-30 | Incyte Holdings Corp | 1h-pyrrolo[2,3-c]pyridin-7(6h)-ones and pyrazolo[3,4-c]pyridin-7(6h)-ones as inhibitors of bet proteins |
| JP6599979B2 (en) | 2014-09-15 | 2019-10-30 | インサイト・コーポレイション | Tricyclic heterocyclic compounds for use as BET protein inhibitors |
| WO2017075377A1 (en) | 2015-10-29 | 2017-05-04 | Incyte Corporation | Amorphous solid form of a bet protein inhibitor |
| FI3472157T3 (en) | 2016-06-20 | 2023-06-01 | Incyte Corp | Crystalline solid forms of a bet inhibitor |
| US20220009894A1 (en) * | 2019-01-23 | 2022-01-13 | Abbisko Therapeutics Co., Ltd. | 1,2,3,4-tetrahydroquinoxaline derivative, preparation method therefor and application thereof |
| JPWO2021107066A1 (en) | 2019-11-28 | 2021-06-03 | ||
| US11833155B2 (en) | 2020-06-03 | 2023-12-05 | Incyte Corporation | Combination therapy for treatment of myeloproliferative neoplasms |
| CN112409493B (en) * | 2020-08-12 | 2022-09-30 | 浙江工业大学 | Recombinant fusion enzyme and application thereof in synthesis of methyl glyoxylate |
| CN114075212B (en) * | 2020-08-14 | 2023-05-12 | 江苏恒瑞医药股份有限公司 | Fused tricyclic derivatives, preparation method thereof and application thereof in medicines |
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| AU710825B2 (en) * | 1996-02-21 | 1999-09-30 | Darwin Discovery Limited | Quinolones and their therapeutic use |
| DE19946289A1 (en) | 1999-09-28 | 2001-03-29 | Basf Ag | Benzodiazepine derivatives, their production and use |
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| US7026311B2 (en) | 2002-01-10 | 2006-04-11 | Abbott Gmbh & Co., Kg | Dibenzodiazepine derivatives, their preparation and use |
| JP2004256531A (en) | 2003-02-07 | 2004-09-16 | Takeda Chem Ind Ltd | Tricyclic ring compound, method for producing the same and use of the same |
| US20060178359A1 (en) | 2003-02-07 | 2006-08-10 | Mitsuru Shiraishi | Tricyclic compound, process for producing the same, and use |
| TW200637862A (en) | 2005-01-10 | 2006-11-01 | Tibotec Pharm Ltd | 1,5,6-substituted-2-oxo-3-cyano-1,6a-diaza-tetrahydro-fluoranthenes |
| CA2616020A1 (en) * | 2005-08-05 | 2007-02-15 | Astrazeneca Ab | Tricyclic benzimidazoles and their use as metabotropic glutamate receptor modulators |
| US7939545B2 (en) | 2006-05-16 | 2011-05-10 | Boehringer Ingelheim International Gmbh | Inhibitors of human immunodeficiency virus replication |
| EP2220095B1 (en) | 2007-11-15 | 2013-01-02 | Gilead Sciences, Inc. | Inhibitors of human immunodeficiency virus replication |
| JP5269086B2 (en) | 2007-11-15 | 2013-08-21 | ギリアード サイエンシス インコーポレーテッド | Human immunodeficiency virus replication inhibitor |
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| EP2511273B8 (en) * | 2011-04-15 | 2019-06-26 | Hivih | Inhibitors of viral replication, their process of preparation and their therapeutical uses |
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| TW201720798A (en) | 2015-09-17 | 2017-06-16 | Ｖｉｉｖ醫療保健英國有限公司 | Benzoazepine derivatives |
| JP2018536000A (en) | 2015-12-04 | 2018-12-06 | ヴィーブ ヘルスケア ユーケー リミテッド | Isoindoline derivatives |
| EP3383866A1 (en) | 2015-12-04 | 2018-10-10 | ViiV Healthcare UK Limited | Tetrahydroisoquinoline derivatives |
| JP2018535993A (en) | 2015-12-04 | 2018-12-06 | ヴィーブ ヘルスケア ユーケー リミテッド | Isoindoline derivatives |
| WO2017093937A1 (en) | 2015-12-04 | 2017-06-08 | Viiv Healthcare Uk Limited | Isoindoline derivatives |
-
2016
- 2016-05-27 CA CA2987384A patent/CA2987384A1/en not_active Abandoned
- 2016-05-27 MX MX2017015256A patent/MX2017015256A/en unknown
- 2016-05-27 CN CN201680043904.XA patent/CN107922423B/en not_active Expired - Fee Related
- 2016-05-27 AU AU2016271762A patent/AU2016271762B2/en not_active Ceased
- 2016-05-27 CN CN202010066935.5A patent/CN111138458A/en active Pending
- 2016-05-27 EP EP16803241.5A patent/EP3305789A4/en not_active Withdrawn
- 2016-05-27 JP JP2017521897A patent/JP6614585B2/en not_active Expired - Fee Related
- 2016-05-27 KR KR1020177037486A patent/KR20180011267A/en unknown
- 2016-05-27 SG SG11201709634QA patent/SG11201709634QA/en unknown
- 2016-05-27 RU RU2017145082A patent/RU2720145C2/en active
- 2016-05-27 TW TW105116757A patent/TWI700284B/en not_active IP Right Cessation
- 2016-05-27 WO PCT/JP2016/065702 patent/WO2016194806A1/en active Application Filing
- 2016-05-27 BR BR112017025367-4A patent/BR112017025367A2/en active Search and Examination
- 2016-05-27 MA MA043120A patent/MA43120A/en unknown
- 2016-05-27 US US15/577,795 patent/US10494380B2/en not_active Expired - Fee Related
-
2017
- 2017-11-09 IL IL255580A patent/IL255580B/en active IP Right Grant
-
2018
- 2018-10-05 HK HK18112740.8A patent/HK1253539A1/en unknown
-
2019
- 2019-10-28 US US16/665,231 patent/US10870661B2/en active Active
- 2019-10-29 JP JP2019196066A patent/JP6797464B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| RU2017145082A3 (en) | 2019-10-24 |
| AU2016271762A1 (en) | 2017-11-30 |
| JP6797464B2 (en) | 2020-12-09 |
| US10494380B2 (en) | 2019-12-03 |
| EP3305789A4 (en) | 2018-11-21 |
| MX2017015256A (en) | 2018-02-19 |
| US20200055873A1 (en) | 2020-02-20 |
| BR112017025367A2 (en) | 2018-08-07 |
| CN107922423A (en) | 2018-04-17 |
| JP6614585B2 (en) | 2019-12-04 |
| KR20180011267A (en) | 2018-01-31 |
| MA43120A (en) | 2018-09-05 |
| JPWO2016194806A1 (en) | 2018-03-22 |
| CN107922423B (en) | 2020-10-27 |
| RU2720145C2 (en) | 2020-04-24 |
| TW201706275A (en) | 2017-02-16 |
| IL255580B (en) | 2020-11-30 |
| US10870661B2 (en) | 2020-12-22 |
| CN111138458A (en) | 2020-05-12 |
| AU2016271762B2 (en) | 2020-01-23 |
| TWI700284B (en) | 2020-08-01 |
| IL255580A (en) | 2018-01-31 |
| JP2020097568A (en) | 2020-06-25 |
| RU2017145082A (en) | 2019-07-01 |
| US20180162876A1 (en) | 2018-06-14 |
| EP3305789A1 (en) | 2018-04-11 |
| CA2987384A1 (en) | 2016-12-08 |
| WO2016194806A1 (en) | 2016-12-08 |
| HK1253539A1 (en) | 2019-06-21 |
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