SG11201708841SA - Sequence-specific detection and phenotype determination - Google Patents
Sequence-specific detection and phenotype determinationInfo
- Publication number
- SG11201708841SA SG11201708841SA SG11201708841SA SG11201708841SA SG11201708841SA SG 11201708841S A SG11201708841S A SG 11201708841SA SG 11201708841S A SG11201708841S A SG 11201708841SA SG 11201708841S A SG11201708841S A SG 11201708841SA SG 11201708841S A SG11201708841S A SG 11201708841SA
- Authority
- SG
- Singapore
- Prior art keywords
- sequence
- specific detection
- phenotype determination
- phenotype
- determination
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562155011P | 2015-04-30 | 2015-04-30 | |
| PCT/EP2016/059518 WO2016174151A1 (en) | 2015-04-30 | 2016-04-28 | Sequence-specific detection and phenotype determination |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201708841SA true SG11201708841SA (en) | 2017-11-29 |
Family
ID=55953128
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201708841SA SG11201708841SA (en) | 2015-04-30 | 2016-04-28 | Sequence-specific detection and phenotype determination |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US10227661B2 (en) |
| EP (1) | EP3289100B1 (en) |
| JP (1) | JP6826048B2 (en) |
| CN (1) | CN107532215A (en) |
| CA (1) | CA2983217C (en) |
| ES (1) | ES2761631T3 (en) |
| HK (1) | HK1248772A1 (en) |
| SG (1) | SG11201708841SA (en) |
| WO (1) | WO2016174151A1 (en) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013066438A2 (en) | 2011-07-22 | 2013-05-10 | President And Fellows Of Harvard College | Evaluation and improvement of nuclease cleavage specificity |
| US20150044192A1 (en) | 2013-08-09 | 2015-02-12 | President And Fellows Of Harvard College | Methods for identifying a target site of a cas9 nuclease |
| US9359599B2 (en) | 2013-08-22 | 2016-06-07 | President And Fellows Of Harvard College | Engineered transcription activator-like effector (TALE) domains and uses thereof |
| US9228207B2 (en) | 2013-09-06 | 2016-01-05 | President And Fellows Of Harvard College | Switchable gRNAs comprising aptamers |
| US9322037B2 (en) | 2013-09-06 | 2016-04-26 | President And Fellows Of Harvard College | Cas9-FokI fusion proteins and uses thereof |
| US9526784B2 (en) | 2013-09-06 | 2016-12-27 | President And Fellows Of Harvard College | Delivery system for functional nucleases |
| US11053481B2 (en) | 2013-12-12 | 2021-07-06 | President And Fellows Of Harvard College | Fusions of Cas9 domains and nucleic acid-editing domains |
| AU2015298571B2 (en) | 2014-07-30 | 2020-09-03 | President And Fellows Of Harvard College | Cas9 proteins including ligand-dependent inteins |
| US9879328B2 (en) * | 2014-11-21 | 2018-01-30 | GeneWeave Biosciences, Inc. | Mechanisms of antimicrobial susceptibility |
| JP7109784B2 (en) | 2015-10-23 | 2022-08-01 | プレジデント アンド フェローズ オブ ハーバード カレッジ | Evolved Cas9 protein for gene editing |
| JP2019509746A (en) | 2016-03-28 | 2019-04-11 | ザ・チャールズ・スターク・ドレイパ・ラボラトリー・インコーポレイテッド | Bacteriophage modification method |
| CN110214183A (en) | 2016-08-03 | 2019-09-06 | 哈佛大学的校长及成员们 | Adenosine nucleobase editing machine and application thereof |
| US11661590B2 (en) | 2016-08-09 | 2023-05-30 | President And Fellows Of Harvard College | Programmable CAS9-recombinase fusion proteins and uses thereof |
| WO2018039438A1 (en) | 2016-08-24 | 2018-03-01 | President And Fellows Of Harvard College | Incorporation of unnatural amino acids into proteins using base editing |
| SG11201903089RA (en) | 2016-10-14 | 2019-05-30 | Harvard College | Aav delivery of nucleobase editors |
| US10745677B2 (en) | 2016-12-23 | 2020-08-18 | President And Fellows Of Harvard College | Editing of CCR5 receptor gene to protect against HIV infection |
| EP3592853A1 (en) | 2017-03-09 | 2020-01-15 | President and Fellows of Harvard College | Suppression of pain by gene editing |
| JP2020510439A (en) | 2017-03-10 | 2020-04-09 | プレジデント アンド フェローズ オブ ハーバード カレッジ | Base-editing factor from cytosine to guanine |
| IL306092A (en) | 2017-03-23 | 2023-11-01 | Harvard College | Nucleobase editors comprising nucleic acid programmable dna binding proteins |
| WO2018209320A1 (en) | 2017-05-12 | 2018-11-15 | President And Fellows Of Harvard College | Aptazyme-embedded guide rnas for use with crispr-cas9 in genome editing and transcriptional activation |
| EP3658573A1 (en) | 2017-07-28 | 2020-06-03 | President and Fellows of Harvard College | Methods and compositions for evolving base editors using phage-assisted continuous evolution (pace) |
| EP3676376A2 (en) | 2017-08-30 | 2020-07-08 | President and Fellows of Harvard College | High efficiency base editors comprising gam |
| CN111757937A (en) | 2017-10-16 | 2020-10-09 | 布罗德研究所股份有限公司 | Use of adenosine base editor |
| CN107904208B (en) * | 2017-12-25 | 2019-11-01 | 云舟生物科技（广州）有限公司 | Cell clone for cell phenotype research and screening method and application thereof |
| US10450616B1 (en) | 2018-05-09 | 2019-10-22 | Talis Biomedical Corporation | Polynucleotides for the amplification and detection of Chlamydia trachomatis |
| CN109628616A (en) * | 2018-12-17 | 2019-04-16 | 博奥生物集团有限公司 | For detecting the LAMP primer composition and its application of Carbapenem-resistant gene NDM1-24 hypotype |
| CN113227404A (en) * | 2018-12-27 | 2021-08-06 | 豪夫迈·罗氏有限公司 | Non-replicating transduction particles and transduction particle-based reporter systems for detecting acinetobacter baumannii |
| US20220073969A1 (en) * | 2018-12-29 | 2022-03-10 | Roche Molecular Systems, Inc. | Use of sideromycins to limit cross-reactivity and improve species identification in antibiotic susceptibility assays |
| WO2020191241A1 (en) | 2019-03-19 | 2020-09-24 | The Broad Institute, Inc. | Methods and compositions for editing nucleotide sequences |
| WO2020245123A1 (en) * | 2019-06-06 | 2020-12-10 | F. Hoffmann-La Roche Ag | Use of peptidomimetic antimicrobial peptides to limit cross-reactivity and improve bacterial identification in antibiotic susceptibility assays |
| US10954572B2 (en) | 2019-07-25 | 2021-03-23 | Talis Biomedical Corporation | Polynucleotides for the amplification and detection of Neisseria gonorrhoeae |
| US11891662B2 (en) | 2019-12-02 | 2024-02-06 | Talis Biomedical Corporation | Polynucleotides for amplification and detection of human beta actin |
| CA3177481A1 (en) | 2020-05-08 | 2021-11-11 | David R. Liu | Methods and compositions for simultaneous editing of both strands of a target double-stranded nucleotide sequence |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE149208T1 (en) * | 1988-10-04 | 1997-03-15 | Dna Plant Techn Corp | BACTERIAL DETECTION BY PHAGE TRANSDUCTION OF DETECTED PHENOTYPES |
| US5714331A (en) | 1991-05-24 | 1998-02-03 | Buchardt, Deceased; Ole | Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility |
| US5539082A (en) | 1993-04-26 | 1996-07-23 | Nielsen; Peter E. | Peptide nucleic acids |
| US5736388A (en) | 1994-12-30 | 1998-04-07 | Chada; Sunil | Bacteriophage-mediated gene transfer systems capable of transfecting eukaryotic cells |
| US6274316B1 (en) * | 1997-07-03 | 2001-08-14 | Id Biomedical Corporation | Compositions and methods for detecting vancomycin resistant enterococci by cycling probe reactions |
| WO2001012803A2 (en) * | 1999-08-17 | 2001-02-22 | Beth Israel Deaconess Medical Center, Inc. | Methods and compositions for restoring antibiotic susceptibility in glycopeptide-resistant enterococcus |
| AU2277401A (en) * | 1999-12-23 | 2001-07-09 | Elitra Pharmaceuticals, Inc. | Genes identified as required for proliferation of e. coli |
| WO2002079467A2 (en) | 2001-03-29 | 2002-10-10 | Københavns Universitet | Antibiotic-free bacterial strain selection with antisense molecules |
| US20090155768A1 (en) * | 2004-04-07 | 2009-06-18 | Dean Scholl | Reporter plasmid phage packaging system for detection of bacteria |
| EP2147125A4 (en) * | 2007-04-18 | 2010-12-15 | Univ Cornell | Microorganism detection method and apparatus |
| US8329889B2 (en) * | 2008-02-15 | 2012-12-11 | Trustees Of Boston University | In vivo gene sensors |
| WO2010048511A1 (en) * | 2008-10-24 | 2010-04-29 | Becton, Dickinson And Company | Antibiotic susceptibility profiling methods |
| US9801948B2 (en) | 2011-09-21 | 2017-10-31 | Yale University | Antimicrobial compositions and methods of use thereof |
| WO2014124226A1 (en) | 2013-02-07 | 2014-08-14 | The Rockefeller University | Sequence specific antimicrobials |
| US9481903B2 (en) | 2013-03-13 | 2016-11-01 | Roche Molecular Systems, Inc. | Systems and methods for detection of cells using engineered transduction particles |
| BR112015023108A8 (en) * | 2013-03-13 | 2018-01-23 | Geneweave Biosciences Inc | bacterial cell packaging system, method for packaging a reporter nucleic acid molecule, composition, method for detecting a bacterial cell presence or absence in a sample, vector, method for detecting a target transcript in a cell, method for detect the presence of a bacterial cell in a sample and kit. |
| DK3041498T3 (en) | 2013-09-05 | 2022-05-09 | Massachusetts Inst Technology | RECONCILIATION OF MICROBIAL POPULATIONS WITH PROGRAMMABLE NUCLEASES |
| US9540675B2 (en) | 2013-10-29 | 2017-01-10 | GeneWeave Biosciences, Inc. | Reagent cartridge and methods for detection of cells |
-
2016
- 2016-04-22 US US15/136,646 patent/US10227661B2/en active Active
- 2016-04-28 CN CN201680024151.8A patent/CN107532215A/en active Pending
- 2016-04-28 ES ES16721390T patent/ES2761631T3/en active Active
- 2016-04-28 WO PCT/EP2016/059518 patent/WO2016174151A1/en active Application Filing
- 2016-04-28 CA CA2983217A patent/CA2983217C/en active Active
- 2016-04-28 JP JP2017556945A patent/JP6826048B2/en active Active
- 2016-04-28 SG SG11201708841SA patent/SG11201708841SA/en unknown
- 2016-04-28 EP EP16721390.9A patent/EP3289100B1/en active Active
-
2018
- 2018-06-27 HK HK18108242.9A patent/HK1248772A1/en unknown
-
2019
- 2019-01-10 US US16/245,093 patent/US10822664B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2983217A1 (en) | 2016-11-03 |
| CN107532215A (en) | 2018-01-02 |
| US10822664B2 (en) | 2020-11-03 |
| US20160319378A1 (en) | 2016-11-03 |
| CA2983217C (en) | 2022-01-11 |
| EP3289100B1 (en) | 2019-10-09 |
| HK1248772A1 (en) | 2018-10-19 |
| EP3289100A1 (en) | 2018-03-07 |
| JP2018520640A (en) | 2018-08-02 |
| US10227661B2 (en) | 2019-03-12 |
| WO2016174151A1 (en) | 2016-11-03 |
| JP6826048B2 (en) | 2021-02-03 |
| US20190127810A1 (en) | 2019-05-02 |
| ES2761631T3 (en) | 2020-05-20 |
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