SG11201707970XA - Ex vivo proliferation of epithelial cells - Google Patents
Ex vivo proliferation of epithelial cellsInfo
- Publication number
- SG11201707970XA SG11201707970XA SG11201707970XA SG11201707970XA SG11201707970XA SG 11201707970X A SG11201707970X A SG 11201707970XA SG 11201707970X A SG11201707970X A SG 11201707970XA SG 11201707970X A SG11201707970X A SG 11201707970XA SG 11201707970X A SG11201707970X A SG 11201707970XA
- Authority
- SG
- Singapore
- Prior art keywords
- epithelial cells
- vivo proliferation
- proliferation
- vivo
- epithelial
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0688—Cells from the lungs or the respiratory tract
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
- C12N5/0629—Keratinocytes; Whole skin
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0681—Cells of the genital tract; Non-germinal cells from gonads
- C12N5/0683—Cells of the male genital tract, e.g. prostate, epididymis; Non-germinal cells from testis, e.g. Leydig cells, Sertoli cells
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/12—Light metals, i.e. alkali, alkaline earth, Be, Al, Mg
- C12N2500/14—Calcium; Ca chelators; Calcitonin
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/99—Serum-free medium
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/11—Epidermal growth factor [EGF]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/113—Acidic fibroblast growth factor (aFGF, FGF-1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/117—Keratinocyte growth factors (KGF-1, i.e. FGF-7; KGF-2, i.e. FGF-12)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/15—Transforming growth factor beta (TGF-β)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
- C12N2501/72—Transferases (EC 2.)
- C12N2501/727—Kinases (EC 2.7.)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/999—Small molecules not provided for elsewhere
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/54—Collagen; Gelatin
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Toxicology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562142851P | 2015-04-03 | 2015-04-03 | |
US201562217406P | 2015-09-11 | 2015-09-11 | |
US201662294896P | 2016-02-12 | 2016-02-12 | |
PCT/US2016/025396 WO2016161192A1 (en) | 2015-04-03 | 2016-03-31 | Ex vivo proliferation of epithelial cells |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201707970XA true SG11201707970XA (en) | 2017-10-30 |
Family
ID=55806770
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201707970XA SG11201707970XA (en) | 2015-04-03 | 2016-03-31 | Ex vivo proliferation of epithelial cells |
SG10201902872YA SG10201902872YA (en) | 2015-04-03 | 2016-03-31 | Ex vivo proliferation of epithelial cells |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201902872YA SG10201902872YA (en) | 2015-04-03 | 2016-03-31 | Ex vivo proliferation of epithelial cells |
Country Status (13)
Country | Link |
---|---|
US (7) | US10119121B2 (en) |
EP (2) | EP3822339A1 (en) |
JP (2) | JP6964068B2 (en) |
KR (1) | KR102598772B1 (en) |
CN (1) | CN107636149A (en) |
AU (1) | AU2016243750B2 (en) |
CA (1) | CA2981708A1 (en) |
DK (1) | DK3277799T3 (en) |
HK (1) | HK1249919A1 (en) |
IL (1) | IL254588B (en) |
MX (1) | MX2017012206A (en) |
SG (2) | SG11201707970XA (en) |
WO (1) | WO2016161192A1 (en) |
Families Citing this family (18)
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CN107636149A (en) | 2015-04-03 | 2018-01-26 | 普罗帕格尼克斯公司 | The vitro proliferation of epithelial cell |
US10100285B2 (en) | 2015-04-03 | 2018-10-16 | Propagenix Inc. | Ex vivo proliferation of epithelial cells |
DK3347450T3 (en) | 2015-09-11 | 2021-05-31 | Propagenix Inc | EX VIVO PROLIFERATION OF EPITHEL CELLS |
HU231285B1 (en) | 2018-04-18 | 2022-08-28 | Printnet Kereskedelmi És Szolgáltató Kft. | Compounds for selectively inhibiting myosin ii isoforms |
WO2020041065A1 (en) | 2018-08-20 | 2020-02-27 | Propagenix Inc. | Epithelial cell spheroids |
KR20200032830A (en) * | 2018-09-19 | 2020-03-27 | 메디칸(주) | Method and Apparatus for Self-Culturing Autologous Stem Cell |
WO2020072791A1 (en) | 2018-10-03 | 2020-04-09 | Stembiosys, Inc. | Amniotic fluid cell-derived extracellular matrix and uses thereof |
CN109294972A (en) * | 2018-10-17 | 2019-02-01 | 南京农业大学 | A kind of lamb intestinal epithelial cell extracorporeal culturing method |
JP6692593B1 (en) * | 2018-10-17 | 2020-05-13 | 株式会社マンダム | Observation method of sebaceous gland and its use |
US11034669B2 (en) | 2018-11-30 | 2021-06-15 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
KR102639023B1 (en) | 2019-02-21 | 2024-02-20 | 스템바이오시스, 인크. | Methods for cardiomyocyte maturation on amniotic fluid cell-derived ECM, cellular structure, and use for cardiotoxicity and proarrhythmia screening of drug compounds |
WO2021050430A1 (en) * | 2019-09-09 | 2021-03-18 | The Regents Of The University Of Michigan | Development of embryonic-like tissue from stem cells |
CN113249325B (en) * | 2020-02-11 | 2023-02-17 | 合肥中科普瑞昇生物医药科技有限公司 | Culture medium and culture method of esophageal squamous carcinoma primary cells |
WO2021203911A1 (en) * | 2020-04-09 | 2021-10-14 | 中国医学科学院阜外医院 | Composition for cryopreservation of myocardial cells |
CN115873797A (en) * | 2021-09-29 | 2023-03-31 | 北京干细胞与再生医学研究院 | Amplification culture medium and culture method for retinal pigment epithelial cells |
CN114181889B (en) * | 2021-11-24 | 2023-10-10 | 中国人民解放军总医院 | Primary sweat gland cell conditioned medium and primary sweat gland cell culture method |
CN117018032A (en) * | 2022-05-10 | 2023-11-10 | 上海赛立维生物科技有限公司 | Biological agent containing skeletal muscle precursor-like cells, and preparation method and application thereof |
CN117503800B (en) * | 2024-01-04 | 2024-04-05 | 北京益华生物科技有限公司 | Gastric mucosa epithelial cell extract and preparation method and application thereof |
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CN107636149A (en) | 2015-04-03 | 2018-01-26 | 普罗帕格尼克斯公司 | The vitro proliferation of epithelial cell |
US10100285B2 (en) | 2015-04-03 | 2018-10-16 | Propagenix Inc. | Ex vivo proliferation of epithelial cells |
DK3347450T3 (en) | 2015-09-11 | 2021-05-31 | Propagenix Inc | EX VIVO PROLIFERATION OF EPITHEL CELLS |
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2016
- 2016-03-31 CN CN201680029217.2A patent/CN107636149A/en active Pending
- 2016-03-31 DK DK16718065.2T patent/DK3277799T3/en active
- 2016-03-31 EP EP20196509.2A patent/EP3822339A1/en active Pending
- 2016-03-31 KR KR1020177031915A patent/KR102598772B1/en active IP Right Grant
- 2016-03-31 SG SG11201707970XA patent/SG11201707970XA/en unknown
- 2016-03-31 MX MX2017012206A patent/MX2017012206A/en unknown
- 2016-03-31 CA CA2981708A patent/CA2981708A1/en active Pending
- 2016-03-31 AU AU2016243750A patent/AU2016243750B2/en active Active
- 2016-03-31 EP EP16718065.2A patent/EP3277799B1/en active Active
- 2016-03-31 WO PCT/US2016/025396 patent/WO2016161192A1/en active Application Filing
- 2016-03-31 JP JP2018502619A patent/JP6964068B2/en active Active
- 2016-03-31 SG SG10201902872YA patent/SG10201902872YA/en unknown
- 2016-10-18 US US15/296,920 patent/US10119121B2/en active Active
- 2016-10-18 US US15/296,831 patent/US9790471B2/en active Active
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2017
- 2017-08-24 US US15/685,853 patent/US9963680B2/en active Active
- 2017-09-19 IL IL254588A patent/IL254588B/en active IP Right Grant
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2018
- 2018-03-14 US US15/921,546 patent/US10711251B2/en active Active
- 2018-03-14 US US15/921,536 patent/US10711250B2/en active Active
- 2018-07-18 HK HK18109288.2A patent/HK1249919A1/en unknown
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2020
- 2020-05-08 JP JP2020082484A patent/JP2020120686A/en active Pending
- 2020-06-12 US US16/899,989 patent/US11680246B2/en active Active
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2023
- 2023-05-08 US US18/144,733 patent/US20230416686A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2018512890A (en) | 2018-05-24 |
US10711250B2 (en) | 2020-07-14 |
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CA2981708A1 (en) | 2016-10-06 |
EP3277799A1 (en) | 2018-02-07 |
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