SG11201707583RA - MODULATION OF TUMOR IMMUNITY BY PROTEIN-MEDIATED 0<sb>2</sb> DELIVERY - Google Patents

MODULATION OF TUMOR IMMUNITY BY PROTEIN-MEDIATED 0<sb>2</sb> DELIVERY

Info

Publication number
SG11201707583RA
SG11201707583RA SG11201707583RA SG11201707583RA SG11201707583RA SG 11201707583R A SG11201707583R A SG 11201707583RA SG 11201707583R A SG11201707583R A SG 11201707583RA SG 11201707583R A SG11201707583R A SG 11201707583RA SG 11201707583R A SG11201707583R A SG 11201707583RA
Authority
SG
Singapore
Prior art keywords
mediated
modulation
protein
delivery
tumor immunity
Prior art date
Application number
SG11201707583RA
Inventor
Stephen P L Cary
Ana Krtolica
Moan Natacha Le
Jonathan A Winger
Kevin G Leong
Original Assignee
Omniox Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Omniox Inc filed Critical Omniox Inc
Publication of SG11201707583RA publication Critical patent/SG11201707583RA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1092Details
    • A61N2005/1098Enhancing the effect of the particle by an injected agent or implanted device
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SG11201707583RA 2015-03-17 2016-03-17 MODULATION OF TUMOR IMMUNITY BY PROTEIN-MEDIATED 0<sb>2</sb> DELIVERY SG11201707583RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562134523P 2015-03-17 2015-03-17
PCT/US2016/022981 WO2016149562A2 (en) 2015-03-17 2016-03-17 Modulation of tumor immunity by protein-mediated 02 delivery

Publications (1)

Publication Number Publication Date
SG11201707583RA true SG11201707583RA (en) 2017-10-30

Family

ID=56297072

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201707583RA SG11201707583RA (en) 2015-03-17 2016-03-17 MODULATION OF TUMOR IMMUNITY BY PROTEIN-MEDIATED 0<sb>2</sb> DELIVERY
SG10201908269S SG10201908269SA (en) 2015-03-17 2016-03-17 Modulation of tumor immunity by protein-mediated o2 delivery

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10201908269S SG10201908269SA (en) 2015-03-17 2016-03-17 Modulation of tumor immunity by protein-mediated o2 delivery

Country Status (15)

Country Link
US (2) US20180243364A1 (en)
EP (1) EP3270961A2 (en)
JP (2) JP7049832B2 (en)
KR (1) KR20170132789A (en)
CN (1) CN107580499A (en)
AU (1) AU2016232866B2 (en)
BR (1) BR112017019862A2 (en)
CA (1) CA2979974A1 (en)
HK (2) HK1249416A1 (en)
IL (1) IL254507B (en)
MA (1) MA41788A (en)
MX (1) MX2017011847A (en)
RU (1) RU2731450C2 (en)
SG (2) SG11201707583RA (en)
WO (1) WO2016149562A2 (en)

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US10385116B2 (en) * 2013-01-07 2019-08-20 Omniox, Inc. Polymeric forms of H-NOX proteins
WO2018009528A1 (en) * 2016-07-05 2018-01-11 Tdw Group Combination cancer immunotherapies with arginine depletion agents
EP3836911A1 (en) * 2018-08-15 2021-06-23 Omniox, Inc. H-nox proteins for treating cardiovascular and pulmonary conditions
PE20220231A1 (en) 2019-06-25 2022-02-07 Gilead Sciences Inc FLT3L-FC FUSION PROTEINS AND METHODS OF USE
JP7371243B2 (en) 2019-10-18 2023-10-30 フォーティ セブン, インコーポレイテッド Combination therapy to treat myelodysplastic syndromes and acute myeloid leukemia
CN114599392A (en) 2019-10-31 2022-06-07 四十七公司 anti-CD 47 and anti-CD 20 based treatment of leukemia
TWI778443B (en) 2019-11-12 2022-09-21 美商基利科學股份有限公司 Mcl1 inhibitors
IL294032A (en) 2019-12-24 2022-08-01 Carna Biosciences Inc Diacylglycerol kinase modulating compounds
CA3169451A1 (en) 2020-02-14 2021-08-19 Jounce Therapeutics, Inc. Antibodies and fusion proteins that bind to ccr8 and uses thereof
EP4143194A1 (en) 2020-05-01 2023-03-08 Gilead Sciences, Inc. Cd73 inhibiting 2,4-dioxopyrimidine compounds
US20240139280A1 (en) * 2021-04-14 2024-05-02 OncoC4, Inc. Use of hif-1-alpha inhibitors in cancer immunotherapy
TW202302145A (en) 2021-04-14 2023-01-16 美商基利科學股份有限公司 Co-inhibition of cd47/sirpα binding and nedd8-activating enzyme e1 regulatory subunit for the treatment of cancer
TW202313094A (en) 2021-05-18 2023-04-01 美商基利科學股份有限公司 Methods of using flt3l-fc fusion proteins
AU2022299051A1 (en) 2021-06-23 2023-12-07 Gilead Sciences, Inc. Diacylglyercol kinase modulating compounds
WO2022271677A1 (en) 2021-06-23 2022-12-29 Gilead Sciences, Inc. Diacylglyercol kinase modulating compounds
US11926628B2 (en) 2021-06-23 2024-03-12 Gilead Sciences, Inc. Diacylglyercol kinase modulating compounds
WO2022271659A1 (en) 2021-06-23 2022-12-29 Gilead Sciences, Inc. Diacylglyercol kinase modulating compounds
TW202330504A (en) 2021-10-28 2023-08-01 美商基利科學股份有限公司 Pyridizin-3(2h)-one derivatives
AU2022376954A1 (en) 2021-10-29 2024-05-02 Gilead Sciences, Inc. Cd73 compounds
US20230242508A1 (en) 2021-12-22 2023-08-03 Gilead Sciences, Inc. Ikaros zinc finger family degraders and uses thereof
WO2023122581A2 (en) 2021-12-22 2023-06-29 Gilead Sciences, Inc. Ikaros zinc finger family degraders and uses thereof
TW202340168A (en) 2022-01-28 2023-10-16 美商基利科學股份有限公司 Parp7 inhibitors
EP4245756A1 (en) 2022-03-17 2023-09-20 Gilead Sciences, Inc. Ikaros zinc finger family degraders and uses thereof
US20230355796A1 (en) 2022-03-24 2023-11-09 Gilead Sciences, Inc. Combination therapy for treating trop-2 expressing cancers
TW202345901A (en) 2022-04-05 2023-12-01 美商基利科學股份有限公司 Combination therapy for treating colorectal cancer
TW202400138A (en) 2022-04-21 2024-01-01 美商基利科學股份有限公司 Kras g12d modulating compounds
WO2023235716A2 (en) * 2022-05-31 2023-12-07 Cardiff Oncology, Inc. Cancer treatment using topoisomerase i inhibitors and plk1 inhibitors
WO2024006929A1 (en) 2022-07-01 2024-01-04 Gilead Sciences, Inc. Cd73 compounds
US20240091351A1 (en) 2022-09-21 2024-03-21 Gilead Sciences, Inc. FOCAL IONIZING RADIATION AND CD47/SIRPa DISRUPTION ANTICANCER COMBINATION THERAPY

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US5295944A (en) * 1991-05-14 1994-03-22 Dana-Farber Cancer Institute Method for treating a tumor with ionizing radiation
AU2001294999A1 (en) * 2000-08-07 2002-02-18 Corixa Corporation Compositions and methods for the therapy and diagnosis of colon cancer
US20050176108A1 (en) * 2003-03-13 2005-08-11 Young-Min Kim Physiologically active polypeptide conjugate having prolonged in vivo half-life
CN106075388B (en) * 2006-05-22 2021-06-29 加利福尼亚大学董事会 Compositions and methods for delivering nitric oxide
US20110288023A1 (en) * 2007-06-08 2011-11-24 The Regents Of The University Of California Office Of Technology Transfer Cancer drug delivery using modified transferrin
US20100183545A1 (en) * 2008-10-14 2010-07-22 The United States Of America, As Represented By The Secretary, Targeted cargo protein combination therapy
JP2011168521A (en) * 2010-02-18 2011-09-01 Eci Inc PEGYLATED eMIP, METHOD FOR PRODUCING THE SAME AND CANCER THERAPEUTIC AGENT USING THE SAME
US7989593B1 (en) * 2010-05-27 2011-08-02 Bing Lou Wong Method for the preparation of a high-temperature stable oxygen-carrier-containing pharmaceutical composition and the use thereof
US10385116B2 (en) * 2013-01-07 2019-08-20 Omniox, Inc. Polymeric forms of H-NOX proteins
US10094835B2 (en) * 2013-05-09 2018-10-09 Mayo Foundation For Medical Education And Research Treating patients based on immune subtypes
EP3003316B1 (en) * 2013-05-31 2020-07-22 Merck Sharp & Dohme Corp. Combination therapies for cancer
JOP20200094A1 (en) * 2014-01-24 2017-06-16 Dana Farber Cancer Inst Inc Antibody molecules to pd-1 and uses thereof

Also Published As

Publication number Publication date
SG10201908269SA (en) 2019-10-30
AU2016232866A1 (en) 2017-10-12
IL254507A0 (en) 2017-11-30
US20220160823A1 (en) 2022-05-26
RU2731450C2 (en) 2020-09-03
CN107580499A (en) 2018-01-12
JP2020183450A (en) 2020-11-12
WO2016149562A2 (en) 2016-09-22
HK1250137A1 (en) 2018-11-30
MX2017011847A (en) 2018-06-06
WO2016149562A3 (en) 2016-11-03
CA2979974A1 (en) 2016-09-22
JP2018511595A (en) 2018-04-26
JP7049832B2 (en) 2022-04-07
MA41788A (en) 2021-03-31
RU2017134953A3 (en) 2019-12-26
RU2017134953A (en) 2019-04-08
IL254507B (en) 2022-07-01
HK1249416A1 (en) 2018-11-02
KR20170132789A (en) 2017-12-04
BR112017019862A2 (en) 2018-05-29
AU2016232866B2 (en) 2021-10-21
EP3270961A2 (en) 2018-01-24
US20180243364A1 (en) 2018-08-30

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