SG11201707128TA - Method of treating a brain tumor - Google Patents

Method of treating a brain tumor

Info

Publication number
SG11201707128TA
SG11201707128TA SG11201707128TA SG11201707128TA SG11201707128TA SG 11201707128T A SG11201707128T A SG 11201707128TA SG 11201707128T A SG11201707128T A SG 11201707128TA SG 11201707128T A SG11201707128T A SG 11201707128TA SG 11201707128T A SG11201707128T A SG 11201707128TA
Authority
SG
Singapore
Prior art keywords
treating
brain tumor
tumor
brain
Prior art date
Application number
SG11201707128TA
Inventor
Lan Huang
Original Assignee
Beyondspring Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=56880412&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201707128T(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Beyondspring Pharmaceuticals Inc filed Critical Beyondspring Pharmaceuticals Inc
Publication of SG11201707128TA publication Critical patent/SG11201707128TA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41881,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965Non-condensed pyrazines
    • A61K31/497Non-condensed pyrazines containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG11201707128TA 2015-03-06 2016-03-02 Method of treating a brain tumor SG11201707128TA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562129623P 2015-03-06 2015-03-06
US201562249807P 2015-11-02 2015-11-02
PCT/US2016/020396 WO2016144636A1 (en) 2015-03-06 2016-03-02 Method of treating a brain tumor

Publications (1)

Publication Number Publication Date
SG11201707128TA true SG11201707128TA (en) 2017-09-28

Family

ID=56880412

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201707128TA SG11201707128TA (en) 2015-03-06 2016-03-02 Method of treating a brain tumor

Country Status (17)

Country Link
US (2) US10076518B2 (en)
EP (1) EP3265091A4 (en)
JP (2) JP6904570B2 (en)
KR (1) KR102623404B1 (en)
CN (1) CN107530340B (en)
AU (2) AU2016229295B2 (en)
BR (1) BR112017018964A2 (en)
CA (1) CA2978679A1 (en)
CL (1) CL2017002242A1 (en)
HK (2) HK1250007A1 (en)
IL (1) IL254262A0 (en)
MX (1) MX2017011375A (en)
MY (1) MY194341A (en)
RU (1) RU2728796C2 (en)
SG (1) SG11201707128TA (en)
WO (1) WO2016144636A1 (en)
ZA (1) ZA201706035B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2017011375A (en) 2015-03-06 2018-01-23 Beyondspring Pharmaceuticals Inc Method of treating a brain tumor.
KR102626155B1 (en) 2015-03-06 2024-01-17 비욘드스프링 파마수티컬스, 인코포레이티드. RAS omitted
EP4011878A1 (en) 2015-07-13 2022-06-15 Beyondspring Pharmaceuticals, Inc. Plinabulin compositions
CA3013467A1 (en) 2016-02-08 2017-08-17 Beyondspring Pharmaceuticals, Inc. Compositions containing tucaresol or its analogs
KR20230018545A (en) 2016-06-06 2023-02-07 비욘드스프링 파마수티컬스, 인코포레이티드. Composition and method for reducing neutropenia
JP2020503363A (en) 2017-01-06 2020-01-30 ビヨンドスプリング ファーマシューティカルズ,インコーポレイテッド Tubulin binding compounds and their therapeutic use
KR20190109479A (en) 2017-02-01 2019-09-25 비욘드스프링 파마수티컬스, 인코포레이티드. How to reduce neutropenia
JP7350015B2 (en) * 2018-01-24 2023-09-25 ビヨンドスプリング ファーマシューティカルズ,インコーポレイテッド Compositions and methods for reducing thrombocytopenia due to administration of plinabulin
WO2020018700A1 (en) * 2018-07-18 2020-01-23 Manzanita Pharmaceuticals, Inc. Conjugates for delivering an anti-cancer agent to nerve cells, methods of use and methods of making thereof
US20230061353A1 (en) * 2020-01-22 2023-03-02 Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Abt-751 and ionizing radiation
MX2022012711A (en) * 2020-04-10 2023-01-16 Lantern Pharma Inc Hydroxyureamethyl-acylfulvene for treating brain cancer or cns cancer.
JP2024505392A (en) * 2021-01-08 2024-02-06 ランタン ファルマ インコーポレイテッド Treatment of brain metastases and CNS metastases with ildin or hydroxyureamethylacylfulvene
EP4319751A1 (en) * 2021-04-09 2024-02-14 Beyondspring Pharmaceuticals, Inc. Therapeutic compositions and methods for treating tumors
CN117860672A (en) * 2022-10-11 2024-04-12 大连万春布林医药有限公司 Plinabulin micelle composition and preparation method thereof

Family Cites Families (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS509164A (en) 1973-05-11 1975-01-30
AU576322B2 (en) 1983-07-22 1988-08-25 Ici Australia Limited Alpha-substituted-alpha-cyanomethyl alcohols
US4783443A (en) 1986-03-03 1988-11-08 The University Of Chicago Amino acyl cephalosporin derivatives
JPS6411523A (en) 1987-07-06 1989-01-17 Kawashima Tekko Kk Dish feeder in tableware washing machine
JPH059164A (en) 1991-07-02 1993-01-19 Sumitomo Chem Co Ltd Production of optically active mandelonitrile derivative
GB9217331D0 (en) 1992-08-14 1992-09-30 Xenova Ltd Pharmaceutical compounds
EP1500393A1 (en) 1992-11-27 2005-01-26 Mayne Pharma (USA) Inc. Injectable composition containing taxol
JPH0725858A (en) 1993-07-13 1995-01-27 Otsuka Pharmaceut Co Ltd Piperazine derivative
GB9402807D0 (en) 1994-02-14 1994-04-06 Xenova Ltd Pharmaceutical compounds
GB9402809D0 (en) 1994-02-14 1994-04-06 Xenova Ltd Pharmaceutical compounds
GB9426224D0 (en) 1994-12-23 1995-02-22 Xenova Ltd Pharmaceutical compounds
US5891877A (en) 1995-02-14 1999-04-06 Xenova Limited Pharmaceutical compounds
US5874443A (en) 1995-10-19 1999-02-23 Trega Biosciences, Inc. Isoquinoline derivatives and isoquinoline combinatorial libraries
US5886210A (en) 1996-08-22 1999-03-23 Rohm And Haas Company Method for preparing aromatic compounds
JP3131574B2 (en) 1996-09-04 2001-02-05 新日本製鐵株式会社 Novel antitumor substance, microorganism and method for producing the substance, and cell cycle inhibitor and antitumor agent containing the substance as active ingredient
US5939098A (en) * 1996-09-19 1999-08-17 Schering Corporation Cancer treatment with temozolomide
US5922683A (en) 1997-05-29 1999-07-13 Abbott Laboratories Multicyclic erythromycin derivatives
CA2310664C (en) 1997-11-21 2008-03-11 Euro-Celtique S.A. Substituted 2-aminoacetamides and the use thereof
SK10642000A3 (en) 1998-01-29 2001-07-10 Aventis Pharmaceuticals Products Inc. Method for preparing an n-[(aliphatic or aromatic)carbonyl]-2-aminoacetamide compound and a cyclyzed compound
US7141603B2 (en) 1999-02-19 2006-11-28 The Regents Of The University California Antitumor agents
US6069146A (en) 1998-03-25 2000-05-30 The Regents Of The University Of California Halimide, a cytotoxic marine natural product, and derivatives thereof
IL137974A0 (en) 1998-03-26 2001-10-31 Shionogi & Co Indole derivatives having antiviral activity
US6509331B1 (en) 1998-06-22 2003-01-21 Elan Pharmaceuticals, Inc. Deoxyamino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
FR2784988B1 (en) 1998-10-23 2002-09-20 Adir NOVEL DIHYDRO AND TETRAHYDROQUINOLEINIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
US7026322B2 (en) 1998-11-12 2006-04-11 Nereus Pharmaceuticals, Inc. Phenylahistin and the phenylahistin analogs, a new class of anti-tumor compounds
US6358957B1 (en) 1998-11-12 2002-03-19 Nereus Pharmaceuticals, Inc. Phenylahistin and the phenylahistin analogs, a new class of anti-tumor compounds
US6936704B1 (en) 1999-08-23 2005-08-30 Dana-Farber Cancer Institute, Inc. Nucleic acids encoding costimulatory molecule B7-4
BR0013581A (en) 1999-08-23 2002-07-02 Dana Faber Cancer Inst Inc Pd-1, a receiver for b7-4, and uses for it
CA2392477A1 (en) 1999-11-30 2001-06-07 Mayo Foundation For Medical Education And Research B7-h1, a novel immunoregulatory molecule
MXPA02006826A (en) 2000-01-18 2004-04-05 Nereus Phamraceuticals Inc Cell division inhibitors and process for producing the same.
CZ301743B6 (en) 2000-05-09 2010-06-09 Angiorx Corporation Piperazinedione compounds and their use for treating neoplastic diseases
EP1345938A1 (en) 2000-12-28 2003-09-24 Neurocrine Biosciences, Inc. Tricyclic crf receptor antagonists
US7012100B1 (en) 2002-06-04 2006-03-14 Avolix Pharmaceuticals, Inc. Cell migration inhibiting compositions and methods and compositions for treating cancer
US7935704B2 (en) 2003-08-01 2011-05-03 Nereus Pharmaceuticals, Inc. Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof
CN100540548C (en) 2002-08-02 2009-09-16 尼瑞斯药品公司 Synthesizing of dehydrophenylahistin and analogue thereof and dehydrophenylahistin and analogue thereof
US7919497B2 (en) 2002-08-02 2011-04-05 Nereus Pharmaceuticals, Inc. Analogs of dehydrophenylahistins and their therapeutic use
ATE514713T1 (en) 2002-12-23 2011-07-15 Wyeth Llc ANTIBODIES TO PD-1 AND THEIR USE
NZ548659A (en) * 2004-02-04 2011-01-28 Nereus Pharmaceuticals Inc Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof
DE202004018940U1 (en) 2004-12-07 2006-04-13 Asf Verwaltungs Gmbh Snap closure, snap-fastener tape and resealable bag
DK2439273T3 (en) 2005-05-09 2019-06-03 Ono Pharmaceutical Co HUMAN MONOCLONAL ANTIBODIES FOR PROGRAMMED DEATH-1 (PD-1) AND PROCEDURES FOR TREATMENT OF CANCER USING ANTI-PD-1 ANTIBODIES ALONE OR IN COMBINATION WITH OTHER IMMUNTER APPLICATIONS
CA3201163A1 (en) 2005-07-01 2007-01-11 E. R. Squibb & Sons, L.L.C. Human monoclonal antibodies to programmed death ligand 1 (pd-l1)
JP2009523813A (en) * 2006-01-18 2009-06-25 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング Specific therapies using integrin ligands to treat cancer
US8129527B2 (en) 2006-11-03 2012-03-06 Nereus Pharmacuticals, Inc. Analogs of dehydrophenylahistins and their therapeutic use
ES2558568T3 (en) 2008-01-08 2016-02-05 Bristol-Myers Squibb Company Combination of anti-CTLA4 antibody with tubulin modulating agents for the treatment of proliferative diseases
WO2009114335A2 (en) 2008-03-12 2009-09-17 Merck & Co., Inc. Pd-1 binding proteins
HRP20240240T1 (en) 2008-12-09 2024-04-26 F. Hoffmann - La Roche Ag Anti-pd-l1 antibodies and their use to enhance t-cell function
WO2010114922A1 (en) * 2009-03-31 2010-10-07 Agios Pharmaceuticals, Inc. Methods of treating cancer having an aberrant egfr or kras genotype
GB0907551D0 (en) 2009-05-01 2009-06-10 Univ Dundee Treatment or prophylaxis of proliferative conditions
PL2464218T3 (en) * 2009-08-10 2015-12-31 Univ Texas Treatment of brain metastases with inhibitors of endothelin receptors in combination with a cytotoxic chemotherapy agent
PL2504364T3 (en) 2009-11-24 2017-12-29 Medimmune Limited Targeted binding agents against b7-h1
US20130064831A1 (en) 2010-05-17 2013-03-14 Bristol-Myers Squibb Company Immunotherapeutic dosing regimens and combinations thereof
EP2576514A1 (en) * 2010-06-04 2013-04-10 Exonhit Sa Substituted isoquinolines and their use as tubulin polymerization inhibitors
JP2012033526A (en) 2010-07-28 2012-02-16 Fuji Electric Co Ltd Thin film solar cell and method for manufacturing the same
WO2012035436A1 (en) 2010-09-15 2012-03-22 Tokyo University Of Pharmacy And Life Sciences Plinabulin prodrug analogs and therapeutic uses thereof
TWI386203B (en) * 2011-01-07 2013-02-21 Univ China Medical Pharmaceutical composition for treating brain cancer or reducing temozolomide-resistance of brain cancer cells and uses of the same
RU2625034C2 (en) 2011-04-20 2017-07-11 МЕДИММЬЮН, ЭлЭлСи Antibodies and other molecules binding b7-h1 and pd-1
AU2013204313C1 (en) * 2012-06-01 2016-04-07 Bionomics Limited Combination Therapy
CA2905418C (en) 2013-03-13 2023-03-28 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods for modulating chemotherapeutic cytotoxicity
WO2014174480A1 (en) * 2013-04-24 2014-10-30 Tel Hashomer Medical Research Infrastructure And Services Ltd. Magnetic resonance maps for analyzing tissue
MY185650A (en) 2013-10-11 2021-05-27 Beyondspring Inc Cancer treatment with combinantion of plinabulin and taxane
US9850225B2 (en) 2014-04-14 2017-12-26 Bristol-Myers Squibb Company Compounds useful as immunomodulators
MY193968A (en) 2015-02-12 2022-11-03 Beyondspring Pharmaceuticals Inc Use of plinabulin in combination with immune checkpoint inhibitors
KR102626155B1 (en) 2015-03-06 2024-01-17 비욘드스프링 파마수티컬스, 인코포레이티드. RAS omitted
MX2017011375A (en) 2015-03-06 2018-01-23 Beyondspring Pharmaceuticals Inc Method of treating a brain tumor.
EP4011878A1 (en) 2015-07-13 2022-06-15 Beyondspring Pharmaceuticals, Inc. Plinabulin compositions
CA3013467A1 (en) 2016-02-08 2017-08-17 Beyondspring Pharmaceuticals, Inc. Compositions containing tucaresol or its analogs
KR20230018545A (en) 2016-06-06 2023-02-07 비욘드스프링 파마수티컬스, 인코포레이티드. Composition and method for reducing neutropenia
JP2020503363A (en) 2017-01-06 2020-01-30 ビヨンドスプリング ファーマシューティカルズ,インコーポレイテッド Tubulin binding compounds and their therapeutic use
KR20190109479A (en) 2017-02-01 2019-09-25 비욘드스프링 파마수티컬스, 인코포레이티드. How to reduce neutropenia
CN110603037A (en) 2017-03-13 2019-12-20 大连万春布林医药有限公司 Plinabulin compositions and uses thereof

Also Published As

Publication number Publication date
US20180042921A1 (en) 2018-02-15
CA2978679A1 (en) 2016-09-15
US20190000841A1 (en) 2019-01-03
CN107530340A (en) 2018-01-02
AU2016229295B2 (en) 2021-11-04
RU2017131448A3 (en) 2019-08-20
AU2016229295A1 (en) 2017-09-28
IL254262A0 (en) 2017-10-31
EP3265091A1 (en) 2018-01-10
CN107530340B (en) 2021-06-08
BR112017018964A2 (en) 2018-05-22
KR102623404B1 (en) 2024-01-11
JP2021091695A (en) 2021-06-17
JP7264331B2 (en) 2023-04-25
WO2016144636A1 (en) 2016-09-15
MX2017011375A (en) 2018-01-23
HK1250007A1 (en) 2018-11-23
CL2017002242A1 (en) 2018-04-02
ZA201706035B (en) 2019-12-18
AU2021254549A1 (en) 2021-11-18
KR20170123642A (en) 2017-11-08
RU2017131448A (en) 2019-04-08
US10076518B2 (en) 2018-09-18
HK1249051A1 (en) 2018-10-26
RU2728796C2 (en) 2020-07-31
US10357491B2 (en) 2019-07-23
JP2018507245A (en) 2018-03-15
EP3265091A4 (en) 2018-08-01
JP6904570B2 (en) 2021-07-21
MY194341A (en) 2022-11-29

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