SG11201706352QA - System and methods for calibrating binding dyes - Google Patents

System and methods for calibrating binding dyes

Info

Publication number
SG11201706352QA
SG11201706352QA SG11201706352QA SG11201706352QA SG11201706352QA SG 11201706352Q A SG11201706352Q A SG 11201706352QA SG 11201706352Q A SG11201706352Q A SG 11201706352QA SG 11201706352Q A SG11201706352Q A SG 11201706352QA SG 11201706352Q A SG11201706352Q A SG 11201706352QA
Authority
SG
Singapore
Prior art keywords
calibrating
methods
binding dyes
dyes
binding
Prior art date
Application number
SG11201706352QA
Inventor
Yong Chu
Jacob Freudenthal
Jeffrey Marks
Original Assignee
Life Technologies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Life Technologies Corp filed Critical Life Technologies Corp
Publication of SG11201706352QA publication Critical patent/SG11201706352QA/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • G01N21/274Calibration, base line adjustment, drift correction
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/686Polymerase chain reaction [PCR]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6452Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6456Spatial resolved fluorescence measurements; Imaging
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N2021/6417Spectrofluorimetric devices
    • G01N2021/6421Measuring at two or more wavelengths
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • G01N2021/6441Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks with two or more labels
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/12Circuits of general importance; Signal processing
    • G01N2201/127Calibration; base line adjustment; drift compensation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Optics & Photonics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Mathematical Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
SG11201706352QA 2015-02-06 2016-02-05 System and methods for calibrating binding dyes SG11201706352QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562113118P 2015-02-06 2015-02-06
PCT/US2016/016817 WO2016127080A1 (en) 2015-02-06 2016-02-05 System and methods for calibrating binding dyes

Publications (1)

Publication Number Publication Date
SG11201706352QA true SG11201706352QA (en) 2017-09-28

Family

ID=55453275

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201706352QA SG11201706352QA (en) 2015-02-06 2016-02-05 System and methods for calibrating binding dyes

Country Status (9)

Country Link
US (1) US10501788B2 (en)
EP (1) EP3254083B1 (en)
JP (1) JP6789227B2 (en)
KR (1) KR102370360B1 (en)
CN (1) CN107407631B (en)
BR (1) BR112017016935B1 (en)
RU (1) RU2017131051A (en)
SG (1) SG11201706352QA (en)
WO (1) WO2016127080A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114414542B (en) * 2021-12-20 2024-01-12 成都瀚辰光翼科技有限责任公司 Fluorescent signal detection method, device, medium and equipment for gene detection

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0814828A (en) * 1994-06-29 1996-01-19 Kobe Steel Ltd Calibration method for stereoscopic image sensor and device therefor
AU8846498A (en) * 1997-08-07 1999-03-01 Imaging Research, Inc. A digital imaging system for assays in well plates, gels and blots
ES2183563T3 (en) * 1998-05-19 2003-03-16 Cepheid MULTICHANNEL OPTICAL DETECTION SYSTEM.
US6905881B2 (en) * 2000-11-30 2005-06-14 Paul Sammak Microbead-based test plates and test methods for fluorescence imaging systems
US8084260B2 (en) * 2004-11-24 2011-12-27 Applied Biosystems, Llc Spectral calibration method and system for multiple instruments
US7663750B2 (en) * 2005-06-30 2010-02-16 Applied Biosystems, Llc Two-dimensional spectral imaging system
US7630849B2 (en) * 2005-09-01 2009-12-08 Applied Biosystems, Llc Method of automated calibration and diagnosis of laboratory instruments
CN101268355A (en) * 2005-09-21 2008-09-17 卢米尼克斯股份有限公司 Methods and systems for image data processing
WO2008003053A2 (en) * 2006-06-28 2008-01-03 Applera Corporation Minimizing effects of dye crosstalk
US20080001099A1 (en) * 2006-07-01 2008-01-03 Sharaf Muhammad A Quantitative calibration method and system for genetic analysis instrumentation
US20080182263A1 (en) 2007-01-29 2008-07-31 Applera Corporation Systems and Methods for Calibration Using Dye Signal Amplification
CA2752760C (en) * 2009-04-15 2019-12-24 Biocartis Sa Optical detection system for monitoring rtpcr reaction
JP5985140B2 (en) * 2010-04-28 2016-09-06 ソニー株式会社 Fluorescence intensity correction method, fluorescence intensity calculation method, and fluorescence intensity calculation apparatus
JP5081313B2 (en) * 2011-04-06 2012-11-28 アイシン精機株式会社 Car camera calibration system
CN102411024B (en) * 2011-06-15 2014-07-09 公安部第一研究所 Capillary array electrophoresis detection method based on spatial correction and spectral correction
US9245169B2 (en) * 2012-06-15 2016-01-26 Luminex Corporation Apparatus, system, and method for image normalization using a Gaussian residual of fit selection criteria

Also Published As

Publication number Publication date
EP3254083A1 (en) 2017-12-13
BR112017016935B1 (en) 2021-04-20
US20160230209A1 (en) 2016-08-11
CN107407631A (en) 2017-11-28
JP2018511786A (en) 2018-04-26
US10501788B2 (en) 2019-12-10
JP6789227B2 (en) 2020-11-25
BR112017016935A2 (en) 2018-04-03
KR20170134358A (en) 2017-12-06
EP3254083B1 (en) 2022-03-02
CN107407631B (en) 2020-11-03
RU2017131051A (en) 2019-03-06
KR102370360B1 (en) 2022-03-04
WO2016127080A1 (en) 2016-08-11

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