SG11201701621YA - Pyrrolopyrimidines for use in influenza virus infection - Google Patents

Pyrrolopyrimidines for use in influenza virus infection

Info

Publication number
SG11201701621YA
SG11201701621YA SG11201701621YA SG11201701621YA SG11201701621YA SG 11201701621Y A SG11201701621Y A SG 11201701621YA SG 11201701621Y A SG11201701621Y A SG 11201701621YA SG 11201701621Y A SG11201701621Y A SG 11201701621YA SG 11201701621Y A SG11201701621Y A SG 11201701621YA
Authority
SG
Singapore
Prior art keywords
pyrrolopyrimidines
influenza virus
virus infection
infection
influenza
Prior art date
Application number
SG11201701621YA
Inventor
Tim Hugo Maria Jonckers
Gowan David Craig Mc
Pierre Jean-Marie Bernard Raboisson
Werner Constant Johan Embrechts
Jérôme Émile Georges Guillemont
Original Assignee
Janssen Sciences Ireland Uc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Sciences Ireland Uc filed Critical Janssen Sciences Ireland Uc
Publication of SG11201701621YA publication Critical patent/SG11201701621YA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs
SG11201701621YA 2014-09-08 2015-09-07 Pyrrolopyrimidines for use in influenza virus infection SG11201701621YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14183984 2014-09-08
PCT/EP2015/070316 WO2016037953A1 (en) 2014-09-08 2015-09-07 Pyrrolopyrimidines for use in influenza virus infection

Publications (1)

Publication Number Publication Date
SG11201701621YA true SG11201701621YA (en) 2017-03-30

Family

ID=51535336

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201701621YA SG11201701621YA (en) 2014-09-08 2015-09-07 Pyrrolopyrimidines for use in influenza virus infection

Country Status (22)

Country Link
US (1) US9932346B2 (en)
EP (1) EP3191489B1 (en)
JP (1) JP6718451B2 (en)
KR (1) KR102531340B1 (en)
CN (1) CN106661036B (en)
AU (1) AU2015314394A1 (en)
BR (1) BR112017004524A2 (en)
CA (1) CA2957475A1 (en)
CL (1) CL2017000533A1 (en)
DK (1) DK3191489T3 (en)
EA (1) EA201790571A1 (en)
ES (1) ES2860688T3 (en)
HR (1) HRP20210038T1 (en)
HU (1) HUE053595T2 (en)
IL (1) IL250955A0 (en)
LT (1) LT3191489T (en)
MX (1) MX2017002972A (en)
PH (1) PH12017500393A1 (en)
SG (1) SG11201701621YA (en)
SI (1) SI3191489T1 (en)
WO (1) WO2016037953A1 (en)
ZA (1) ZA201701643B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20120508A1 (en) 2009-06-17 2012-05-09 Vertex Pharma INHIBITORS OF THE REPLICATION OF FLU VIRUSES
UA118010C2 (en) 2011-08-01 2018-11-12 Вертекс Фармасьютікалз Інкорпорейтед INFLUENCES OF INFLUENZA VIRUS REPLICATION
WO2016183116A1 (en) 2015-05-13 2016-11-17 Vertex Pharmaceuticals Incorporated Methods of preparing inhibitors of influenza viruses replication
JP6857617B2 (en) 2015-05-13 2021-04-14 バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated Influenza virus replication inhibitor
RU2737190C2 (en) 2015-12-09 2020-11-25 Саншайн Лейк Фарма Ко., Лтд. Influenza virus replication inhibitors, methods of application and using
AU2017205261B2 (en) * 2016-01-07 2021-03-25 Janssen Sciences Ireland Uc Functionalized pentanoic acids for use in influenza viral infections
WO2017133669A1 (en) * 2016-02-05 2017-08-10 Savira Pharmaceuticals Gmbh 5, 7-diazaindole and 5, 7-diazaindazole derivatives and their use in the treatment, amelioration or prevention of influenza
WO2017133665A1 (en) * 2016-02-05 2017-08-10 Savira Pharmaceuticals Gmbh 6,7-diazaindazole and 6,7-diazaindole derivatives and use in treatment, amelioration or prevention of influenza thereof
WO2018033082A1 (en) 2016-08-16 2018-02-22 Sunshine Lake Pharma Co., Ltd. Inhibitors of influenza virus replication, application methods and uses thereof
CN106316886A (en) * 2016-08-24 2017-01-11 泰州精英化成医药科技有限公司 Cis form-3- (tert butoxycarbonylamino) naphthenic acid preparing method
CN109641868B (en) * 2016-08-30 2021-12-03 广东东阳光药业有限公司 Inhibitors of influenza virus replication and methods of use and uses thereof
WO2018108125A1 (en) 2016-12-15 2018-06-21 Sunshine Lake Pharma Co., Ltd. Inhibitors of influenza virus replication and uses thereof
JP7299837B2 (en) * 2016-12-23 2023-06-28 アクイナ ファーマシューティカルズ, インコーポレイテッド Compounds, compositions and methods of use
WO2018127096A1 (en) 2017-01-05 2018-07-12 Sunshine Lake Pharma Co., Ltd. Inhibitors of influenza virus replication and uses thereof
US10927118B2 (en) 2017-03-02 2021-02-23 Sunshine Lake Pharma Co., Ltd. Inhibitors of influenza virus replication and uses thereof
EA039181B1 (en) 2017-04-24 2021-12-15 Кокристал Фарма, Инк. Pyrrolopyrimidine derivatives useful as inhibitors of influenza virus replication
CN108727369B (en) * 2017-04-25 2023-06-09 广东东阳光药业有限公司 Influenza virus replication inhibitors and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG151327A1 (en) * 2005-09-30 2009-04-30 Vertex Pharmaceuticals Incopor Deazapurines useful as inhibitors of janus kinases
PE20120508A1 (en) * 2009-06-17 2012-05-09 Vertex Pharma INHIBITORS OF THE REPLICATION OF FLU VIRUSES
WO2012068450A1 (en) * 2010-11-19 2012-05-24 Incyte Corporation Cyclobutyl substituted pyrrolopyridine and pyrrolopyrimidine derivatives as jak inhibitors
CN103492381A (en) 2010-12-16 2014-01-01 沃泰克斯药物股份有限公司 Inhibitors of influenza viruses replication
CN103562205A (en) * 2010-12-16 2014-02-05 沃泰克斯药物股份有限公司 Inhibitors of influenza viruses replication
UA118010C2 (en) 2011-08-01 2018-11-12 Вертекс Фармасьютікалз Інкорпорейтед INFLUENCES OF INFLUENZA VIRUS REPLICATION

Also Published As

Publication number Publication date
BR112017004524A2 (en) 2017-12-05
US9932346B2 (en) 2018-04-03
HUE053595T2 (en) 2021-07-28
EP3191489B1 (en) 2021-01-06
SI3191489T1 (en) 2021-02-26
JP2017527619A (en) 2017-09-21
CN106661036A (en) 2017-05-10
ES2860688T3 (en) 2021-10-05
ES2860688T8 (en) 2022-01-18
US20170253600A1 (en) 2017-09-07
EA201790571A1 (en) 2017-08-31
DK3191489T3 (en) 2021-03-29
ZA201701643B (en) 2018-12-19
WO2016037953A1 (en) 2016-03-17
IL250955A0 (en) 2017-04-30
AU2015314394A1 (en) 2017-03-02
HRP20210038T1 (en) 2021-03-05
JP6718451B2 (en) 2020-07-08
PH12017500393A1 (en) 2017-07-17
LT3191489T (en) 2021-01-25
CA2957475A1 (en) 2016-03-17
CN106661036B (en) 2022-03-15
MX2017002972A (en) 2017-05-30
KR20170054420A (en) 2017-05-17
EP3191489A1 (en) 2017-07-19
KR102531340B1 (en) 2023-05-10
CL2017000533A1 (en) 2017-10-06

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