SG11201610945PA - Modified meningococcal fhbp polypeptides - Google Patents

Modified meningococcal fhbp polypeptides

Info

Publication number
SG11201610945PA
SG11201610945PA SG11201610945PA SG11201610945PA SG11201610945PA SG 11201610945P A SG11201610945P A SG 11201610945PA SG 11201610945P A SG11201610945P A SG 11201610945PA SG 11201610945P A SG11201610945P A SG 11201610945PA SG 11201610945P A SG11201610945P A SG 11201610945PA
Authority
SG
Singapore
Prior art keywords
meningococcal fhbp
fhbp polypeptides
modified meningococcal
modified
polypeptides
Prior art date
Application number
SG11201610945PA
Inventor
Matthew Bottomley
Vega Masignani
Original Assignee
Glaxosmithkline Biolog Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biolog Sa filed Critical Glaxosmithkline Biolog Sa
Publication of SG11201610945PA publication Critical patent/SG11201610945PA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/095Neisseria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/33Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SG11201610945PA 2014-07-17 2015-07-16 Modified meningococcal fhbp polypeptides SG11201610945PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14177564 2014-07-17
PCT/EP2015/066228 WO2016008960A1 (en) 2014-07-17 2015-07-16 Modified meningococcal fhbp polypeptides

Publications (1)

Publication Number Publication Date
SG11201610945PA true SG11201610945PA (en) 2017-01-27

Family

ID=51178812

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201610945PA SG11201610945PA (en) 2014-07-17 2015-07-16 Modified meningococcal fhbp polypeptides

Country Status (18)

Country Link
US (2) US11066450B2 (en)
EP (1) EP3169357B1 (en)
JP (1) JP2017522320A (en)
KR (1) KR20170023191A (en)
CN (1) CN106795208A (en)
AR (1) AR102324A1 (en)
AU (1) AU2015289192A1 (en)
BE (1) BE1022641B1 (en)
BR (1) BR112017000521A2 (en)
CA (1) CA2954745A1 (en)
EA (1) EA201692552A1 (en)
ES (1) ES2722773T3 (en)
IL (1) IL249822A0 (en)
MX (1) MX2017000776A (en)
SG (1) SG11201610945PA (en)
TR (1) TR201901062T4 (en)
WO (1) WO2016008960A1 (en)
ZA (1) ZA201700170B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR201802933T4 (en) 2010-03-30 2018-03-21 Childrens Hospital & Res Center At Oakland The modified factor h binding proteins (fhbp) and their method of use.
BR112016019735A2 (en) * 2014-02-28 2017-10-17 Glaxosmithkline Biologicals Sa fhbp, polypeptide, plasmid or other nucleic acid, host cell, membrane vesicles, and immunogenic composition
JP2017522320A (en) 2014-07-17 2017-08-10 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム Modified meningococcal FHBP polypeptide
CA2954729C (en) 2014-07-17 2023-08-22 Glaxosmithkline Biologicals S.A. Meningococcus vaccines
RU2714248C2 (en) 2014-07-23 2020-02-13 Чилдрен'З Хоспитал Энд Рисёрч Сентер Эт Окленд Versions of factor n-binding protein and methods of use thereof
SI3544637T1 (en) * 2016-11-25 2021-02-26 Glaxosmithkline Biologicals S.A. Native omv-antigen conjugates and use thereof
EP3607967A1 (en) 2018-08-09 2020-02-12 GlaxoSmithKline Biologicals S.A. Modified meningococcal fhbp polypeptides
CN114929660A (en) 2019-12-19 2022-08-19 陶氏技术投资有限责任公司 Process for the preparation of isoprene and mono-olefins comprising at least six carbon atoms
TW202245836A (en) 2021-02-19 2022-12-01 美商賽諾菲巴斯德公司 Meningococcal b recombinant vaccine
GB202115151D0 (en) 2021-10-21 2021-12-08 Glaxosmithkline Biologicals Sa Methods
GB202208093D0 (en) 2022-06-01 2022-07-13 Glaxosmithkline Biologicals Sa Immunogenic composition
GB202208089D0 (en) 2022-06-01 2022-07-13 Glaxosmithkline Biologicals Sa Immunogenic composition
WO2024030931A1 (en) 2022-08-03 2024-02-08 Sanofi Pasteur Inc. Adjuvanted immunogenic composition against neisseria meningitidis b

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6747137B1 (en) 1998-02-13 2004-06-08 Genome Therapeutics Corporation Nucleic acid sequences relating to Candida albicans for diagnostics and therapeutics
US6551795B1 (en) 1998-02-18 2003-04-22 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to pseudomonas aeruginosa for diagnostics and therapeutics
PT1248647E (en) 2000-01-17 2010-11-18 Novartis Vaccines & Diagnostics Srl Outer membrane vesicle (omv) vaccine comprising n. meningitidis serogroup b outer membrane proteins
GB0227346D0 (en) 2002-11-22 2002-12-31 Chiron Spa 741
GB0419408D0 (en) 2004-09-01 2004-10-06 Chiron Srl 741 chimeric polypeptides
GB0419627D0 (en) 2004-09-03 2004-10-06 Chiron Srl Immunogenic bacterial vesicles with outer membrane proteins
GB0524066D0 (en) 2005-11-25 2006-01-04 Chiron Srl 741 ii
AR064642A1 (en) 2006-12-22 2009-04-15 Wyeth Corp POLINUCLEOTIDE VECTOR THAT INCLUDES IT RECOMBINATING CELL THAT UNDERSTANDS THE VECTOR POLYPEPTIDE, ANTIBODY, COMPOSITION THAT UNDERSTANDS THE POLINUCLEOTIDE, VECTOR, RECOMBINATING CELL POLYPEPTIDE OR ANTIBODY, USE OF THE COMPOSITION AND A COMPOSITION AND A METHOD
AU2010310985B2 (en) * 2009-10-27 2014-11-06 Glaxosmithkline Biologicals S.A. Modified meningococcal fHBP polypeptides
US20130004530A1 (en) 2010-03-10 2013-01-03 Jan Poolman Vaccine composition
TR201802933T4 (en) * 2010-03-30 2018-03-21 Childrens Hospital & Res Center At Oakland The modified factor h binding proteins (fhbp) and their method of use.
GB201120634D0 (en) 2011-11-30 2012-01-11 Univ Sheffield Adjuvant polypeptide
EP2861247B1 (en) 2012-06-14 2020-12-09 GlaxoSmithKline Biologicals SA Vaccines for serogroup x meningococcus
GB201215005D0 (en) 2012-08-23 2012-10-10 Isis Innovation Stabilised meningitis vaccine
BR112016019735A2 (en) 2014-02-28 2017-10-17 Glaxosmithkline Biologicals Sa fhbp, polypeptide, plasmid or other nucleic acid, host cell, membrane vesicles, and immunogenic composition
CA2954729C (en) 2014-07-17 2023-08-22 Glaxosmithkline Biologicals S.A. Meningococcus vaccines
JP2017522320A (en) 2014-07-17 2017-08-10 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム Modified meningococcal FHBP polypeptide

Also Published As

Publication number Publication date
CN106795208A (en) 2017-05-31
IL249822A0 (en) 2017-03-30
US20170226161A1 (en) 2017-08-10
JP2017522320A (en) 2017-08-10
US11939357B2 (en) 2024-03-26
MX2017000776A (en) 2017-05-04
US20220002355A1 (en) 2022-01-06
TR201901062T4 (en) 2019-02-21
BE1022641B1 (en) 2016-06-23
EA201692552A1 (en) 2017-06-30
BR112017000521A2 (en) 2017-11-21
AR102324A1 (en) 2017-02-22
KR20170023191A (en) 2017-03-02
EP3169357A1 (en) 2017-05-24
US11066450B2 (en) 2021-07-20
BE1022641A1 (en) 2016-06-23
WO2016008960A1 (en) 2016-01-21
EP3169357B1 (en) 2018-11-07
AU2015289192A1 (en) 2017-02-02
ZA201700170B (en) 2019-06-26
CA2954745A1 (en) 2016-01-21
ES2722773T3 (en) 2019-08-16

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