SG11201610636VA - Pharmaceutical preparation containing entecavir as active ingredient, and preparation method therefor - Google Patents
Pharmaceutical preparation containing entecavir as active ingredient, and preparation method thereforInfo
- Publication number
- SG11201610636VA SG11201610636VA SG11201610636VA SG11201610636VA SG11201610636VA SG 11201610636V A SG11201610636V A SG 11201610636VA SG 11201610636V A SG11201610636V A SG 11201610636VA SG 11201610636V A SG11201610636V A SG 11201610636VA SG 11201610636V A SG11201610636V A SG 11201610636VA
- Authority
- SG
- Singapore
- Prior art keywords
- active ingredient
- preparation
- method therefor
- pharmaceutical preparation
- containing entecavir
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Emergency Medicine (AREA)
- Molecular Biology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20140075457 | 2014-06-20 | ||
PCT/KR2015/006329 WO2015194923A1 (en) | 2014-06-20 | 2015-06-22 | Pharmaceutical preparation containing entecavir as active ingredient, and preparation method therefor |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201610636VA true SG11201610636VA (en) | 2017-01-27 |
Family
ID=54935824
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201610636VA SG11201610636VA (en) | 2014-06-20 | 2015-06-22 | Pharmaceutical preparation containing entecavir as active ingredient, and preparation method therefor |
Country Status (9)
Country | Link |
---|---|
US (1) | US10045993B2 (en) |
EP (1) | EP3158998A4 (en) |
JP (1) | JP6582000B2 (en) |
KR (1) | KR102435064B1 (en) |
CN (1) | CN106573003B (en) |
MY (1) | MY185605A (en) |
PH (1) | PH12016502544B1 (en) |
SG (1) | SG11201610636VA (en) |
WO (1) | WO2015194923A1 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107714676B (en) * | 2017-10-27 | 2020-05-15 | 苏州大学 | Entecavir oral instant film agent and preparation method thereof |
WO2021166987A1 (en) * | 2020-02-19 | 2021-08-26 | 大日本住友製薬株式会社 | Transdermal absorption preparation |
CN114632073A (en) * | 2020-12-15 | 2022-06-17 | 南京海辰药业股份有限公司 | Propofol fumarate and tenofovir oral instant film agent and preparation method thereof |
CN113063881B (en) * | 2021-04-15 | 2023-03-17 | 安徽万邦医药科技股份有限公司 | Related substance analysis method of entecavir oral solution |
CN113730367B (en) * | 2021-09-28 | 2022-12-02 | 海南海灵化学制药有限公司 | Preparation process of entecavir tablets |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1642582A1 (en) * | 2000-02-29 | 2006-04-05 | Bristol-Myers Squibb Company | Low dose entecavir formulation and use |
MY131488A (en) * | 2002-04-08 | 2007-08-30 | Bristol Myers Squibb Co | Low dose liquid entecavir formulations and use |
DE10224612A1 (en) * | 2002-06-04 | 2003-12-24 | Lohmann Therapie Syst Lts | Active substance-containing film-like preparations with improved chemical stability, and process for their preparation |
CN101278938A (en) | 2008-03-20 | 2008-10-08 | 黑龙江加州国际投资咨询有限公司 | Compound preparation of tenofovir and entecavir and its application against hepatitis B virus |
CN101756890A (en) | 2008-11-25 | 2010-06-30 | 天津太平洋制药有限公司 | Parenteral preparation containing active entecavir and preparation method thereof |
US20120328675A1 (en) | 2010-03-03 | 2012-12-27 | Kowa Co., Ltd. | Film preparation containing medicament with unpleasant taste |
US20110290694A1 (en) * | 2010-05-27 | 2011-12-01 | Monosol Rx, Llc | Oral film dosage form having indicia thereon |
KR20120100683A (en) * | 2011-09-09 | 2012-09-12 | (주)차바이오앤디오스텍 | Stable orodispersible film formulation |
US20140315930A1 (en) | 2011-11-14 | 2014-10-23 | Hetero Research Foundation | Fast release solid oral compositions of entecavir |
WO2013114389A1 (en) | 2011-12-21 | 2013-08-08 | Mylan Laboratories Limited. | Process for preparing solid oral formulations comprising low dose of entecavir |
KR101285008B1 (en) | 2012-04-18 | 2013-07-10 | 제일약품주식회사 | A method for preparing oral formulation of low dose entecavir |
CA2779052A1 (en) | 2012-05-31 | 2013-11-30 | Pharmascience Inc. | Pharmaceutical composition of entecavir and process of manufacturing |
KR102142539B1 (en) * | 2012-12-11 | 2020-08-07 | 롯데정밀화학 주식회사 | Composition for complex, complex formed therefrom, and orally ingestible composition including the same |
CN103181903B (en) | 2012-12-21 | 2016-06-01 | 上海景峰制药股份有限公司 | A kind of mixing granulation method of Entecavir |
KR101462018B1 (en) | 2013-04-01 | 2014-11-19 | 썬시스템즈(주) | Orally Disintegrating Film Formulation Containing Entecavir |
CN103301071A (en) | 2013-06-03 | 2013-09-18 | 北京阜康仁生物制药科技有限公司 | Stable entecavir sugarless granules and preparation method thereof |
-
2015
- 2015-06-22 CN CN201580044687.1A patent/CN106573003B/en active Active
- 2015-06-22 US US15/320,446 patent/US10045993B2/en active Active
- 2015-06-22 JP JP2016572806A patent/JP6582000B2/en active Active
- 2015-06-22 SG SG11201610636VA patent/SG11201610636VA/en unknown
- 2015-06-22 KR KR1020150088703A patent/KR102435064B1/en active IP Right Grant
- 2015-06-22 MY MYPI2016704731A patent/MY185605A/en unknown
- 2015-06-22 EP EP15809251.0A patent/EP3158998A4/en not_active Withdrawn
- 2015-06-22 WO PCT/KR2015/006329 patent/WO2015194923A1/en active Application Filing
-
2016
- 2016-12-20 PH PH12016502544A patent/PH12016502544B1/en unknown
Also Published As
Publication number | Publication date |
---|---|
CN106573003B (en) | 2022-04-01 |
EP3158998A1 (en) | 2017-04-26 |
EP3158998A4 (en) | 2018-02-14 |
PH12016502544A1 (en) | 2017-04-10 |
KR102435064B1 (en) | 2022-08-22 |
US20170136025A1 (en) | 2017-05-18 |
KR20150145730A (en) | 2015-12-30 |
JP2017522285A (en) | 2017-08-10 |
MY185605A (en) | 2021-05-25 |
PH12016502544B1 (en) | 2017-04-10 |
WO2015194923A1 (en) | 2015-12-23 |
CN106573003A (en) | 2017-04-19 |
US10045993B2 (en) | 2018-08-14 |
JP6582000B2 (en) | 2019-09-25 |
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