SG11201609570SA - Tank-binding kinase inhibitor compounds - Google Patents
Tank-binding kinase inhibitor compoundsInfo
- Publication number
- SG11201609570SA SG11201609570SA SG11201609570SA SG11201609570SA SG11201609570SA SG 11201609570S A SG11201609570S A SG 11201609570SA SG 11201609570S A SG11201609570S A SG 11201609570SA SG 11201609570S A SG11201609570S A SG 11201609570SA SG 11201609570S A SG11201609570S A SG 11201609570SA
- Authority
- SG
- Singapore
- Prior art keywords
- tank
- kinase inhibitor
- inhibitor compounds
- binding kinase
- binding
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
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- A—HUMAN NECESSITIES
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- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462007322P | 2014-06-03 | 2014-06-03 | |
| PCT/US2015/033769 WO2015187684A1 (en) | 2014-06-03 | 2015-06-02 | Tank-binding kinase inhibitor compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201609570SA true SG11201609570SA (en) | 2016-12-29 |
Family
ID=53546688
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201609570SA SG11201609570SA (en) | 2014-06-03 | 2015-06-02 | Tank-binding kinase inhibitor compounds |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US10072001B2 (en) |
| EP (1) | EP3152210B1 (en) |
| JP (2) | JP6378785B2 (en) |
| KR (2) | KR20180131640A (en) |
| CN (1) | CN106459044A (en) |
| AR (1) | AR100702A1 (en) |
| AU (2) | AU2015271837B2 (en) |
| BR (1) | BR112016028288A2 (en) |
| CA (1) | CA2951126A1 (en) |
| EA (1) | EA031757B1 (en) |
| ES (1) | ES2961577T3 (en) |
| HK (1) | HK1231475A1 (en) |
| IL (1) | IL248888A0 (en) |
| MA (1) | MA40058A (en) |
| MX (1) | MX2016015862A (en) |
| NZ (1) | NZ726317A (en) |
| SG (1) | SG11201609570SA (en) |
| TW (1) | TW201613916A (en) |
| WO (1) | WO2015187684A1 (en) |
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| EA201790395A1 (en) | 2014-09-26 | 2017-08-31 | Джилид Сайэнс, Инк. | AMINOTRIAZIN DERIVATIVES SUITABLE FOR USING AS TANK-BINDING KINASE INHIBITORS |
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| AU2016232705C1 (en) | 2015-03-18 | 2021-06-17 | Arvinas, Inc. | Compounds and methods for the enhanced degradation of targeted proteins |
| WO2016197114A1 (en) | 2015-06-05 | 2016-12-08 | Arvinas, Inc. | Tank-binding kinase-1 protacs and associated methods of use |
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| WO2018053354A1 (en) | 2016-09-15 | 2018-03-22 | Arvinas, Inc. | Indole derivatives as estrogen receptor degraders |
| AU2017341723B2 (en) | 2016-10-11 | 2021-12-16 | Arvinas Operations, Inc. | Compounds and methods for the targeted degradation of androgen receptor |
| CA3042260C (en) | 2016-11-01 | 2023-10-03 | Arvinas, Inc. | Tau-protein targeting protacs and associated methods of use |
| EP3689868B1 (en) | 2016-12-01 | 2023-09-27 | Arvinas Operations, Inc. | Tetrahydronaphthalene and tetrahydroisoquinoline derivatives as estrogen receptor degraders |
| US11173211B2 (en) | 2016-12-23 | 2021-11-16 | Arvinas Operations, Inc. | Compounds and methods for the targeted degradation of rapidly accelerated Fibrosarcoma polypeptides |
| KR102564201B1 (en) | 2016-12-23 | 2023-08-07 | 아비나스 오퍼레이션스, 인코포레이티드 | Compounds and methods for targeted degradation of rapidly progressive fibrosarcoma polypeptides |
| EP3559006A4 (en) | 2016-12-23 | 2021-03-03 | Arvinas Operations, Inc. | Compounds and methods for the targeted degradation of fetal liver kinase polypeptides |
| RU2019121527A (en) | 2016-12-23 | 2021-01-15 | Эрвинэс Оперейшнс, Инк. | CHIMERIC MOLECULES TARGETING EGFR PROTEOLYSIS AND RELATED APPLICATIONS |
| US11191741B2 (en) | 2016-12-24 | 2021-12-07 | Arvinas Operations, Inc. | Compounds and methods for the targeted degradation of enhancer of zeste homolog 2 polypeptide |
| KR20230140606A (en) | 2017-01-26 | 2023-10-06 | 아비나스 오퍼레이션스, 인코포레이티드 | Modulators of estrogen receptor proteolysis and associated methods of use |
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| EP3710443A1 (en) | 2017-11-17 | 2020-09-23 | Arvinas Operations, Inc. | Compounds and methods for the targeted degradation of interleukin-1 receptor-associated kinase 4 polypeptides |
| JP2021512153A (en) | 2018-01-26 | 2021-05-13 | イエール ユニバーシティ | Imide-based modulators of proteolysis and how to use |
| KR20210006356A (en) | 2018-04-04 | 2021-01-18 | 아비나스 오퍼레이션스, 인코포레이티드 | Proteolysis modulators and related methods of use |
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2015
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- 2015-06-01 AR ARP150101733A patent/AR100702A1/en unknown
- 2015-06-02 MA MA040058A patent/MA40058A/en unknown
- 2015-06-02 EP EP15738156.7A patent/EP3152210B1/en active Active
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- 2015-06-02 AU AU2015271837A patent/AU2015271837B2/en not_active Ceased
- 2015-06-02 CA CA2951126A patent/CA2951126A1/en not_active Abandoned
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- 2015-06-02 JP JP2016570275A patent/JP6378785B2/en not_active Expired - Fee Related
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2016
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2017
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| EA201692203A1 (en) | 2017-06-30 |
| CA2951126A1 (en) | 2015-12-10 |
| US10072001B2 (en) | 2018-09-11 |
| EP3152210A1 (en) | 2017-04-12 |
| ES2961577T3 (en) | 2024-03-12 |
| JP2018150358A (en) | 2018-09-27 |
| US10259811B2 (en) | 2019-04-16 |
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| BR112016028288A2 (en) | 2017-08-22 |
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| AU2015271837B2 (en) | 2018-06-14 |
| JP2017516814A (en) | 2017-06-22 |
| AR100702A1 (en) | 2016-10-26 |
| KR20180131640A (en) | 2018-12-10 |
| TW201613916A (en) | 2016-04-16 |
| AU2018208766A1 (en) | 2018-08-16 |
| CN106459044A (en) | 2017-02-22 |
| IL248888A0 (en) | 2017-01-31 |
| WO2015187684A1 (en) | 2015-12-10 |
| KR101926245B1 (en) | 2018-12-06 |
| EA031757B1 (en) | 2019-02-28 |
| AU2015271837A1 (en) | 2016-12-01 |
| NZ726317A (en) | 2018-05-25 |
| JP6378785B2 (en) | 2018-08-22 |
| MX2016015862A (en) | 2017-03-27 |
| MA40058A (en) | 2015-12-10 |
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