SG11201607181WA - Tcr libraries - Google Patents
Tcr librariesInfo
- Publication number
- SG11201607181WA SG11201607181WA SG11201607181WA SG11201607181WA SG11201607181WA SG 11201607181W A SG11201607181W A SG 11201607181WA SG 11201607181W A SG11201607181W A SG 11201607181WA SG 11201607181W A SG11201607181W A SG 11201607181WA SG 11201607181W A SG11201607181W A SG 11201607181WA
- Authority
- SG
- Singapore
- Prior art keywords
- tcr libraries
- tcr
- libraries
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1041—Ribosome/Polysome display, e.g. SPERT, ARM
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
- C40B50/06—Biochemical methods, e.g. using enzymes or whole viable microorganisms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Virology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Computational Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461953114P | 2014-03-14 | 2014-03-14 | |
GB201404536A GB201404536D0 (en) | 2014-03-14 | 2014-03-14 | TCR libraries |
GBGB1421336.7A GB201421336D0 (en) | 2014-12-02 | 2014-12-02 | TCR libraries |
PCT/EP2015/055293 WO2015136072A1 (en) | 2014-03-14 | 2015-03-13 | Tcr libraries |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201607181WA true SG11201607181WA (en) | 2016-09-29 |
Family
ID=54070975
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201607181WA SG11201607181WA (en) | 2014-03-14 | 2015-03-13 | Tcr libraries |
Country Status (14)
Country | Link |
---|---|
US (3) | US20170051036A1 (en) |
EP (2) | EP3116901B1 (en) |
JP (3) | JP2017511151A (en) |
KR (1) | KR102290829B1 (en) |
CN (1) | CN106164091A (en) |
AU (1) | AU2015228751B2 (en) |
BR (1) | BR112016021004A2 (en) |
CA (1) | CA2942433C (en) |
ES (1) | ES2740930T3 (en) |
MX (1) | MX2016011817A (en) |
NZ (1) | NZ724320A (en) |
RU (1) | RU2722696C2 (en) |
SG (1) | SG11201607181WA (en) |
WO (1) | WO2015136072A1 (en) |
Families Citing this family (74)
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KR102423377B1 (en) | 2013-08-05 | 2022-07-25 | 트위스트 바이오사이언스 코포레이션 | De novo synthesized gene libraries |
WO2015153969A1 (en) | 2014-04-04 | 2015-10-08 | The Board Of Trustees Of The Leland Stanford Junior University | Ligand discovery for t cell receptors |
PL3616706T3 (en) | 2014-12-23 | 2022-02-07 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other cancers |
GB201501017D0 (en) | 2014-12-23 | 2015-03-04 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers |
CA2975852A1 (en) | 2015-02-04 | 2016-08-11 | Twist Bioscience Corporation | Methods and devices for de novo oligonucleic acid assembly |
WO2016172377A1 (en) | 2015-04-21 | 2016-10-27 | Twist Bioscience Corporation | Devices and methods for oligonucleic acid library synthesis |
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GB201520566D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
GB201520544D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
GB201520579D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
GB201520558D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
GB201520543D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
GB201520548D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
GB201520568D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd | Peptides |
GB201520567D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
GB201607534D0 (en) | 2016-04-29 | 2016-06-15 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
GB201520597D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
GB201520541D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
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GB201520557D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
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GB201520589D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
GB201604468D0 (en) | 2016-03-16 | 2016-04-27 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
JP6697562B2 (en) | 2015-12-23 | 2020-05-20 | メディジーン イミュノテラピーズ ゲーエムベーハー | Dendritic cell composition |
CN107345242A (en) * | 2016-05-12 | 2017-11-14 | 眭维国 | The processing method of TCR β chain complementary determining regions |
WO2017201019A1 (en) * | 2016-05-17 | 2017-11-23 | Chimera Bioengineering, Inc. | Methods for making novel antigen binding domains |
JP6854340B2 (en) | 2016-08-22 | 2021-04-07 | ツイスト バイオサイエンス コーポレーション | Denovo Synthesized Nucleic Acid Library |
KR102217487B1 (en) | 2016-09-21 | 2021-02-23 | 트위스트 바이오사이언스 코포레이션 | Nucleic acid-based data storage |
KR102614328B1 (en) * | 2016-11-07 | 2023-12-14 | 제노비에 에이비 | Two-part device for T-cell receptor synthesis and stable genomic integration into TCR-presenting cells |
US20210115099A1 (en) | 2016-11-07 | 2021-04-22 | Immunocore Limited | Peptides |
EA201991262A1 (en) * | 2016-12-16 | 2020-04-07 | Твист Байосайенс Корпорейшн | LIBRARIES OF OPTIONS OF IMMUNOLOGICAL SYNAPSIS AND THEIR SYNTHESIS |
EP3586255A4 (en) | 2017-02-22 | 2021-03-31 | Twist Bioscience Corporation | Nucleic acid based data storage |
WO2018170169A1 (en) | 2017-03-15 | 2018-09-20 | Twist Bioscience Corporation | Variant libraries of the immunological synapse and synthesis thereof |
CA3066744A1 (en) | 2017-06-12 | 2018-12-20 | Twist Bioscience Corporation | Methods for seamless nucleic acid assembly |
WO2018231864A1 (en) | 2017-06-12 | 2018-12-20 | Twist Bioscience Corporation | Methods for seamless nucleic acid assembly |
GB201709866D0 (en) | 2017-06-20 | 2017-08-02 | Immunocore Ltd | T cell receptors |
EP3655532B1 (en) * | 2017-07-18 | 2021-08-18 | Genovie AB | A two-component vector library system for rapid assembly and diversification of full-length t-cell receptor open reading frames |
CA3075505A1 (en) | 2017-09-11 | 2019-03-14 | Twist Bioscience Corporation | Gpcr binding proteins and synthesis thereof |
GB2583590A (en) | 2017-10-20 | 2020-11-04 | Twist Bioscience Corp | Heated nanowells for polynucleotide synthesis |
EP3714041A1 (en) | 2017-11-22 | 2020-09-30 | Iovance Biotherapeutics, Inc. | Expansion of peripheral blood lymphocytes (pbls) from peripheral blood |
JP7191448B2 (en) | 2018-01-04 | 2022-12-19 | ツイスト バイオサイエンス コーポレーション | DNA-based digital information storage |
CA3092794A1 (en) * | 2018-03-01 | 2019-09-06 | University Of Kansas | Techniques for generating cell-based therapeutics using recombinant t cell receptor genes |
AU2019270243A1 (en) | 2018-05-18 | 2021-01-07 | Twist Bioscience Corporation | Polynucleotides, reagents, and methods for nucleic acid hybridization |
EP3837373A4 (en) * | 2018-08-13 | 2022-07-06 | Rootpath Genomics, Inc. | High throughput cloning of paired bipartite immunoreceptor polynucleotides and applications thereof |
SG11202109283UA (en) | 2019-02-26 | 2021-09-29 | Twist Bioscience Corp | Variant nucleic acid libraries for antibody optimization |
KR20210136050A (en) | 2019-03-01 | 2021-11-16 | 이오반스 바이오테라퓨틱스, 인크. | Expansion of tumor-infiltrating lymphocytes from liquid tumors and their therapeutic use |
CN114729342A (en) | 2019-06-21 | 2022-07-08 | 特韦斯特生物科学公司 | Barcode-based nucleic acid sequence assembly |
WO2021026266A1 (en) * | 2019-08-05 | 2021-02-11 | Distributed Bio, Inc. | Antigen binding molecules and methods of screening thereof |
CA3161326A1 (en) | 2019-12-11 | 2021-06-17 | Molecular Partners Ag | Designed ankyrin repeat domains with altered surface residues |
GB202010329D0 (en) | 2020-07-06 | 2020-08-19 | Immunocore Ltd | Specific binding molecules |
WO2024038193A1 (en) | 2022-08-18 | 2024-02-22 | Immunocore Limited | Multi-domain binding molecules |
WO2024098024A1 (en) | 2022-11-04 | 2024-05-10 | Iovance Biotherapeutics, Inc. | Expansion of tumor infiltrating lymphocytes from liquid tumors and therapeutic uses thereof |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9718455D0 (en) | 1997-09-02 | 1997-11-05 | Mcgregor Duncan P | Chimeric binding peptide library screening method |
EP1066380B1 (en) | 1998-05-19 | 2001-11-14 | Avidex Ltd | Soluble t cell receptor |
ES2327382T3 (en) | 1999-07-20 | 2009-10-29 | Morphosys Ag | METHODS FOR SUBMITTING (POLI) PEPTIDES / PROTEINS IN PARTICLES OF BACTERIOPHAGES THROUGH DISULFIDE LINKS. |
CA2406668C (en) | 1999-12-06 | 2015-11-24 | Board Of Trustees Of The University Of Illinois | High affinity tcr proteins and methods |
MXPA04001974A (en) | 2001-08-31 | 2004-07-16 | Avidex Ltd | Soluble t cell receptor. |
CA2501870C (en) | 2002-10-09 | 2013-07-02 | Avidex Limited | Single chain recombinant t cell receptors |
NZ570811A (en) * | 2002-11-09 | 2009-11-27 | Immunocore Ltd | T cell receptor display |
DE602005009825D1 (en) | 2004-05-19 | 2008-10-30 | Medigene Ltd | METHOD FOR IMPROVING T-CELL RECEPTORS |
DE602005011617D1 (en) * | 2004-05-19 | 2009-01-22 | Medigene Ltd | HIGH AFFINER NY ESO T CELL RECEPTOR |
GB0411771D0 (en) * | 2004-05-26 | 2004-06-30 | Avidex Ltd | Nucleoproteins displaying native T cell receptor libraries |
GB0411773D0 (en) | 2004-05-26 | 2004-06-30 | Avidex Ltd | Method for the identification of polypeptides which bind to a given peptide mhc complex or cd 1-antigen complex |
ATE475669T1 (en) | 2004-06-29 | 2010-08-15 | Immunocore Ltd | CELLS EXPRESSING A MODIFIED T-CELL RECEPTOR |
EP2197910A2 (en) | 2007-09-25 | 2010-06-23 | The United States of America, as represented by the Secretary, Department of Health and Human Services | Modified t cell receptors and related materials and methods |
GB0908613D0 (en) | 2009-05-20 | 2009-06-24 | Immunocore Ltd | T Cell Reseptors |
MX2013000989A (en) | 2010-07-28 | 2013-03-05 | Immunocore Ltd | T cell receptors. |
CN104520440B (en) * | 2012-05-08 | 2017-10-03 | 适应生物技术公司 | Composition and method for measuring and calibrating the amplification bias in multi-PRC reaction |
GB201516272D0 (en) | 2015-09-15 | 2015-10-28 | Adaptimmune Ltd And Immunocore Ltd | TCR Libraries |
-
2015
- 2015-03-13 SG SG11201607181WA patent/SG11201607181WA/en unknown
- 2015-03-13 RU RU2016140189A patent/RU2722696C2/en active
- 2015-03-13 BR BR112016021004-2A patent/BR112016021004A2/en active Search and Examination
- 2015-03-13 CA CA2942433A patent/CA2942433C/en active Active
- 2015-03-13 CN CN201580013862.0A patent/CN106164091A/en active Pending
- 2015-03-13 EP EP15709505.0A patent/EP3116901B1/en active Active
- 2015-03-13 NZ NZ724320A patent/NZ724320A/en unknown
- 2015-03-13 AU AU2015228751A patent/AU2015228751B2/en active Active
- 2015-03-13 KR KR1020167028338A patent/KR102290829B1/en active IP Right Grant
- 2015-03-13 JP JP2016574488A patent/JP2017511151A/en not_active Withdrawn
- 2015-03-13 MX MX2016011817A patent/MX2016011817A/en active IP Right Grant
- 2015-03-13 ES ES15709505T patent/ES2740930T3/en active Active
- 2015-03-13 WO PCT/EP2015/055293 patent/WO2015136072A1/en active Application Filing
- 2015-03-13 EP EP19178872.8A patent/EP3590958A1/en active Pending
-
2016
- 2016-09-12 US US15/262,160 patent/US20170051036A1/en not_active Abandoned
-
2020
- 2020-03-03 JP JP2020035872A patent/JP7471867B2/en active Active
-
2021
- 2021-05-28 US US17/334,469 patent/US20210371493A1/en not_active Abandoned
-
2022
- 2022-04-12 US US17/719,299 patent/US20220235113A1/en active Pending
- 2022-04-21 JP JP2022070332A patent/JP2022109972A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
NZ724320A (en) | 2022-05-27 |
RU2016140189A (en) | 2018-04-16 |
US20210371493A1 (en) | 2021-12-02 |
ES2740930T3 (en) | 2020-02-07 |
CA2942433C (en) | 2023-08-01 |
RU2722696C2 (en) | 2020-06-03 |
MX2016011817A (en) | 2017-05-12 |
US20220235113A1 (en) | 2022-07-28 |
RU2016140189A3 (en) | 2018-09-04 |
AU2015228751A1 (en) | 2016-09-15 |
EP3116901B1 (en) | 2019-06-12 |
BR112016021004A2 (en) | 2018-01-23 |
KR20170005795A (en) | 2017-01-16 |
AU2015228751B2 (en) | 2019-06-20 |
US20170051036A1 (en) | 2017-02-23 |
EP3590958A1 (en) | 2020-01-08 |
JP2022109972A (en) | 2022-07-28 |
KR102290829B1 (en) | 2021-08-18 |
JP2020114212A (en) | 2020-07-30 |
JP2017511151A (en) | 2017-04-20 |
EP3116901A1 (en) | 2017-01-18 |
CA2942433A1 (en) | 2015-09-17 |
WO2015136072A1 (en) | 2015-09-17 |
JP7471867B2 (en) | 2024-04-22 |
CN106164091A (en) | 2016-11-23 |
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