SG11201606693SA - Novel compounds - Google Patents
Novel compoundsInfo
- Publication number
- SG11201606693SA SG11201606693SA SG11201606693SA SG11201606693SA SG11201606693SA SG 11201606693S A SG11201606693S A SG 11201606693SA SG 11201606693S A SG11201606693S A SG 11201606693SA SG 11201606693S A SG11201606693S A SG 11201606693SA SG 11201606693S A SG11201606693S A SG 11201606693SA
- Authority
- SG
- Singapore
- Prior art keywords
- novel compounds
- novel
- compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/433—Thidiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Ophthalmology & Optometry (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Immunology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Child & Adolescent Psychology (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Reproductive Health (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461968172P | 2014-03-20 | 2014-03-20 | |
EP14185274 | 2014-09-18 | ||
PCT/EP2015/055629 WO2015140195A1 (en) | 2014-03-20 | 2015-03-18 | Novel compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201606693SA true SG11201606693SA (en) | 2016-10-28 |
Family
ID=51564537
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201606693SA SG11201606693SA (en) | 2014-03-20 | 2015-03-18 | Novel compounds |
Country Status (18)
Country | Link |
---|---|
US (1) | US20170107212A1 (en) |
EP (1) | EP3119759A1 (en) |
JP (1) | JP2017509650A (en) |
KR (1) | KR20160127138A (en) |
CN (1) | CN106458983A (en) |
AP (1) | AP2016009432A0 (en) |
AU (1) | AU2015233558A1 (en) |
BR (1) | BR112016021648A2 (en) |
CA (1) | CA2943002A1 (en) |
CR (1) | CR20160433A (en) |
CU (1) | CU20160138A7 (en) |
DO (1) | DOP2016000253A (en) |
EA (1) | EA201691881A1 (en) |
MX (1) | MX2016012175A (en) |
PE (1) | PE20170186A1 (en) |
PH (1) | PH12016501807A1 (en) |
SG (1) | SG11201606693SA (en) |
WO (1) | WO2015140195A1 (en) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2014234472A1 (en) | 2013-03-20 | 2015-10-29 | Bayer Pharma Aktiengesellschaft | 3-acetylamino-1-(phenyl-heteroaryl-aminocarbonyl or phenyl-heteroaryl-carbonylamino)benzene derivatives for the treatment of hyperproliferative disorders |
KR20160127838A (en) * | 2014-03-20 | 2016-11-04 | 바이엘 파마 악티엔게젤샤프트 | Inhibitors of the WNT signalling pathways |
KR20160135283A (en) | 2014-03-20 | 2016-11-25 | 사뮤메드, 엘엘씨 | 5-substituted indazole-3-carboxamides and preparation and use thereof |
CA2988147C (en) | 2015-06-03 | 2023-06-13 | Bristol-Myers Squibb Company | 4-hydroxy-3-(heteroaryl)pyridine-2-one apj agonists for use in the treatment of cardiovascular disorders |
WO2017097215A1 (en) * | 2015-12-07 | 2017-06-15 | 杭州雷索药业有限公司 | Wnt pathway inhibitor embedded with ureas structure |
US11542254B2 (en) | 2016-03-25 | 2023-01-03 | Universisity Of Utah Research Foundation | Methods and composition of 4-substituted benzoylpiperazine-1-substituted carbonyls as beta-catenin/B-cell lymphoma 9 inhibitors |
WO2017167150A1 (en) * | 2016-03-31 | 2017-10-05 | 苏州云轩医药科技有限公司 | 3-fluoropyridine heterocyclic compound and application thereof |
CN115583938A (en) * | 2021-07-05 | 2023-01-10 | 南通聚太生物科技有限公司 | Small molecule compound targeting BCL 9/beta-catenin interaction |
KR20230066213A (en) | 2021-11-06 | 2023-05-15 | 윤보라 | Wireless earphone security system |
TW202334157A (en) * | 2022-01-29 | 2023-09-01 | 大陸商杭州阿諾生物醫藥科技有限公司 | Wnt pathway inhibitor compound |
WO2024022365A1 (en) * | 2022-07-28 | 2024-02-01 | 杭州阿诺生物医药科技有限公司 | Wnt pathway inhibitor compound |
WO2024022521A1 (en) * | 2022-07-28 | 2024-02-01 | 南通环聚泰生物科技有限公司 | SMALL MOLECULE COMPOUND TARGETING BCL9/β-CATENIN INTERACTION |
CN115850202A (en) * | 2022-12-26 | 2023-03-28 | 上海科技大学 | Small molecule inhibitor of frizzled receptor 7 and preparation method and application thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUP0103019A3 (en) * | 1998-08-04 | 2002-01-28 | Astrazeneca Ab | Amide derivatives useful as inhibitors of the production of cytokines, process for producing them and pharmaceutical compositions containing them |
ATE303357T1 (en) * | 1999-03-17 | 2005-09-15 | AMIDE DERIVATIVES | |
WO2013093508A2 (en) * | 2011-12-22 | 2013-06-27 | Oslo University Hospital Hf | Wnt pathway inhibitors |
AU2014234472A1 (en) * | 2013-03-20 | 2015-10-29 | Bayer Pharma Aktiengesellschaft | 3-acetylamino-1-(phenyl-heteroaryl-aminocarbonyl or phenyl-heteroaryl-carbonylamino)benzene derivatives for the treatment of hyperproliferative disorders |
EP2976343A2 (en) * | 2013-03-20 | 2016-01-27 | Bayer Pharma Aktiengesellschaft | Substituted n-biphenyl-3-acetylamino-benzamides and n-[3-(acetylamino)phenyl]-biphenyl-carboxamides and their use as inhibitors of the wnt signalling pathway |
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2015
- 2015-03-18 SG SG11201606693SA patent/SG11201606693SA/en unknown
- 2015-03-18 CR CR20160433A patent/CR20160433A/en unknown
- 2015-03-18 JP JP2016558037A patent/JP2017509650A/en active Pending
- 2015-03-18 CA CA2943002A patent/CA2943002A1/en not_active Abandoned
- 2015-03-18 KR KR1020167028753A patent/KR20160127138A/en unknown
- 2015-03-18 CN CN201580015155.5A patent/CN106458983A/en active Pending
- 2015-03-18 EP EP15710774.9A patent/EP3119759A1/en not_active Withdrawn
- 2015-03-18 AU AU2015233558A patent/AU2015233558A1/en not_active Abandoned
- 2015-03-18 PE PE2016001654A patent/PE20170186A1/en not_active Application Discontinuation
- 2015-03-18 BR BR112016021648A patent/BR112016021648A2/en not_active Application Discontinuation
- 2015-03-18 MX MX2016012175A patent/MX2016012175A/en unknown
- 2015-03-18 US US15/127,780 patent/US20170107212A1/en not_active Abandoned
- 2015-03-18 WO PCT/EP2015/055629 patent/WO2015140195A1/en active Application Filing
- 2015-03-18 AP AP2016009432A patent/AP2016009432A0/en unknown
- 2015-03-18 EA EA201691881A patent/EA201691881A1/en unknown
-
2016
- 2016-09-15 PH PH12016501807A patent/PH12016501807A1/en unknown
- 2016-09-20 DO DO2016000253A patent/DOP2016000253A/en unknown
- 2016-09-20 CU CUP2016000138A patent/CU20160138A7/en unknown
Also Published As
Publication number | Publication date |
---|---|
PH12016501807A1 (en) | 2016-11-21 |
AP2016009432A0 (en) | 2016-09-30 |
AU2015233558A1 (en) | 2016-09-01 |
MX2016012175A (en) | 2017-01-19 |
CA2943002A1 (en) | 2015-09-24 |
CU20160138A7 (en) | 2017-02-02 |
US20170107212A1 (en) | 2017-04-20 |
CN106458983A (en) | 2017-02-22 |
CR20160433A (en) | 2016-12-06 |
BR112016021648A2 (en) | 2017-10-24 |
EA201691881A1 (en) | 2017-12-29 |
PE20170186A1 (en) | 2017-04-01 |
DOP2016000253A (en) | 2016-10-31 |
EP3119759A1 (en) | 2017-01-25 |
JP2017509650A (en) | 2017-04-06 |
WO2015140195A1 (en) | 2015-09-24 |
KR20160127138A (en) | 2016-11-02 |
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