SG11201605790VA - Antimicrobial peptidomimetics - Google Patents

Antimicrobial peptidomimetics

Info

Publication number
SG11201605790VA
SG11201605790VA SG11201605790VA SG11201605790VA SG11201605790VA SG 11201605790V A SG11201605790V A SG 11201605790VA SG 11201605790V A SG11201605790V A SG 11201605790VA SG 11201605790V A SG11201605790V A SG 11201605790VA SG 11201605790V A SG11201605790V A SG 11201605790VA
Authority
SG
Singapore
Prior art keywords
peptidomimetics
antimicrobial
antimicrobial peptidomimetics
Prior art date
Application number
SG11201605790VA
Inventor
Brian Cheng San Chia
Original Assignee
Agency Science Tech & Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB1401036.7A external-priority patent/GB2522412A/en
Application filed by Agency Science Tech & Res filed Critical Agency Science Tech & Res
Priority to SG11201605790VA priority Critical patent/SG11201605790VA/en
Publication of SG11201605790VA publication Critical patent/SG11201605790VA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0812Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/10General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using coupling agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0212Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -N-C-N-C(=0)-, e.g. retro-inverso peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06078Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06086Dipeptides with the first amino acid being basic
    • C07K5/06095Arg-amino acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1024Tetrapeptides with the first amino acid being heterocyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SG11201605790VA 2014-01-22 2015-01-22 Antimicrobial peptidomimetics SG11201605790VA (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SG11201605790VA SG11201605790VA (en) 2014-01-22 2015-01-22 Antimicrobial peptidomimetics

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB1401036.7A GB2522412A (en) 2014-01-22 2014-01-22 Antimicrobial peptidomimetics
SG10201406683W 2014-10-16
SG11201605790VA SG11201605790VA (en) 2014-01-22 2015-01-22 Antimicrobial peptidomimetics
PCT/SG2015/050006 WO2015112093A2 (en) 2014-01-22 2015-01-22 Antimicrobial peptidomimetics

Publications (1)

Publication Number Publication Date
SG11201605790VA true SG11201605790VA (en) 2016-08-30

Family

ID=53682081

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201605790VA SG11201605790VA (en) 2014-01-22 2015-01-22 Antimicrobial peptidomimetics

Country Status (6)

Country Link
US (2) US10053490B2 (en)
EP (1) EP3071591B1 (en)
JP (1) JP6516758B2 (en)
CN (1) CN105934440A (en)
SG (1) SG11201605790VA (en)
WO (1) WO2015112093A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6516758B2 (en) 2014-01-22 2019-05-22 エイジェンシー・フォー・サイエンス,テクノロジー・アンド・リサーチ Antimicrobial peptidomimetic
WO2019027366A1 (en) 2017-08-01 2019-02-07 Agency For Science, Technology And Research Antimicrobial peptidomimetics
CN107540574B (en) * 2017-09-19 2021-06-11 成都西岭源药业有限公司 Preparation method of R-biphenylalaninol

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5776939A (en) * 1997-06-12 1998-07-07 Eli Lilly And Company Drug resistance and multidrug resistance modulators
GB0005703D0 (en) 2000-03-09 2000-05-03 Alpharma As Compounds
US6600015B2 (en) 2000-04-04 2003-07-29 Hoffmann-La Roche Inc. Selective linear peptides with melanocortin-4 receptor (MC4-R) agonist activity
JP2004501191A (en) * 2000-06-28 2004-01-15 テバ ファーマシューティカル インダストリーズ リミティド Carvedilol
US20060128614A1 (en) * 2002-09-20 2006-06-15 Jya-Wei Cheng Antimicrobial peptides with reduced hemolysis and methods of their use
RU2376028C2 (en) * 2004-01-23 2009-12-20 Корнелл Рисеч Фаундейшн, Инк. Method for reduction of oxidising injury (versions)
US8097582B2 (en) * 2006-05-09 2012-01-17 Neobiotics Ab Peptide derivatives useful as antimicrobial agents and for treating wounds
JP2008063285A (en) * 2006-09-08 2008-03-21 Univ Nagoya Method for designing and preparing high-affinity peptide, and the resultant high-affinity peptide
WO2009145839A1 (en) * 2008-04-04 2009-12-03 Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Polyamine compounds that bind tar rna of hiv and methods of treating viral disorders
GB0818074D0 (en) 2008-10-02 2008-11-05 Lytix Biopharma As Treatment of biofilms
DE102009035593A1 (en) 2008-10-29 2010-05-06 Philipps-Universität Marburg New tetrapeptide derivatives are proprotein convertase inhibitors, useful to treat e.g. viral or bacterial diseases, diabetes, arteriosclerosis, cancer, Alzheimer's disease, obesity, and respiratory tract disease
US20120083452A1 (en) * 2010-09-30 2012-04-05 Perricone Nicholas V Topical Anesthetic Uses of Szeto-Schiller Peptides
JP2013538864A (en) 2010-10-08 2013-10-17 ソルヴェイ(ソシエテ アノニム) Biologically active amino acid sequences and uses thereof
CN105126071A (en) * 2011-06-14 2015-12-09 康肽德生物医药技术有限公司 Aromatic-cationic peptides and uses of same
AU2012347931A1 (en) 2011-12-09 2014-07-03 Stealth Peptides International, Inc. Aromatic-cationic peptides and uses of same
WO2013138666A1 (en) * 2012-03-16 2013-09-19 Sanford-Burnham Medical Research Institute Inhibitors of furin and other pro-protein convertases
JP6516758B2 (en) 2014-01-22 2019-05-22 エイジェンシー・フォー・サイエンス,テクノロジー・アンド・リサーチ Antimicrobial peptidomimetic

Also Published As

Publication number Publication date
EP3071591A4 (en) 2017-08-16
US10053490B2 (en) 2018-08-21
US10787483B2 (en) 2020-09-29
US20180354989A1 (en) 2018-12-13
US20160333048A1 (en) 2016-11-17
JP2017507916A (en) 2017-03-23
WO2015112093A2 (en) 2015-07-30
EP3071591A2 (en) 2016-09-28
EP3071591B1 (en) 2021-05-05
CN105934440A (en) 2016-09-07
WO2015112093A3 (en) 2015-11-26
JP6516758B2 (en) 2019-05-22

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