SG11201605449YA - Compounds and compositions for immunotherapy - Google Patents

Compounds and compositions for immunotherapy

Info

Publication number
SG11201605449YA
SG11201605449YA SG11201605449YA SG11201605449YA SG11201605449YA SG 11201605449Y A SG11201605449Y A SG 11201605449YA SG 11201605449Y A SG11201605449Y A SG 11201605449YA SG 11201605449Y A SG11201605449Y A SG 11201605449YA SG 11201605449Y A SG11201605449Y A SG 11201605449YA
Authority
SG
Singapore
Prior art keywords
immunotherapy
compositions
compounds
Prior art date
Application number
SG11201605449YA
Inventor
Lixin Li
Original Assignee
Birdie Biopharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN201410011362.0A external-priority patent/CN104861064A/en
Priority claimed from CN201410011262.8A external-priority patent/CN104861063A/en
Priority claimed from CN201410011324.5A external-priority patent/CN104861067A/en
Application filed by Birdie Biopharmaceuticals Inc filed Critical Birdie Biopharmaceuticals Inc
Publication of SG11201605449YA publication Critical patent/SG11201605449YA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
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    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61K47/6889—Conjugates wherein the antibody being the modifying agent and wherein the linker, binder or spacer confers particular properties to the conjugates, e.g. peptidic enzyme-labile linkers or acid-labile linkers, providing for an acid-labile immuno conjugate wherein the drug may be released from its antibody conjugated part in an acidic, e.g. tumoural or environment
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
SG11201605449YA 2014-01-10 2015-01-08 Compounds and compositions for immunotherapy SG11201605449YA (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CN201410011362.0A CN104861064A (en) 2014-01-10 2014-01-10 EGFR-expressing tumor targeting compound and composition thereof
CN201410011262.8A CN104861063A (en) 2014-01-10 2014-01-10 HER2 positive tumor targeting compound and composition thereof
CN201410011324.5A CN104861067A (en) 2014-01-10 2014-01-10 Compound for immunotherapy, and composition
PCT/CN2015/070379 WO2015103989A1 (en) 2014-01-10 2015-01-08 Compounds and compositions for immunotherapy

Publications (1)

Publication Number Publication Date
SG11201605449YA true SG11201605449YA (en) 2016-08-30

Family

ID=53523554

Family Applications (3)

Application Number Title Priority Date Filing Date
SG11201605296SA SG11201605296SA (en) 2014-01-10 2015-01-08 Compounds and compositions for treating her2 positive tumors
SG11201605455YA SG11201605455YA (en) 2014-01-10 2015-01-08 Compounds and compositions for treating egfr expressing tumors
SG11201605449YA SG11201605449YA (en) 2014-01-10 2015-01-08 Compounds and compositions for immunotherapy

Family Applications Before (2)

Application Number Title Priority Date Filing Date
SG11201605296SA SG11201605296SA (en) 2014-01-10 2015-01-08 Compounds and compositions for treating her2 positive tumors
SG11201605455YA SG11201605455YA (en) 2014-01-10 2015-01-08 Compounds and compositions for treating egfr expressing tumors

Country Status (12)

Country Link
US (11) US10548985B2 (en)
EP (4) EP3092255A4 (en)
JP (5) JP2017503803A (en)
CN (6) CN114671954A (en)
AU (3) AU2015205753A1 (en)
CA (3) CA2936377A1 (en)
DK (1) DK3092256T3 (en)
ES (1) ES2916873T3 (en)
IL (3) IL246680A0 (en)
SG (3) SG11201605296SA (en)
TW (3) TWI691337B (en)
WO (3) WO2015103989A1 (en)

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US20130116404A1 (en) 2011-11-08 2013-05-09 Case Western Reserve University Targeted non-invasive imaging probes of egfr expressing cells
CN112587658A (en) 2012-07-18 2021-04-02 博笛生物科技有限公司 Targeted immunotherapy for cancer
CA2936377A1 (en) * 2014-01-10 2015-07-16 Shanghai Birdie Biotech, Inc. Compounds and compositions for treating egfr expressing tumors
CA2954446A1 (en) 2014-07-09 2016-01-14 Shanghai Birdie Biotech, Inc. Anti-pd-l1 combinations for treating tumors
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