SG11201601889YA - Antibacterial 2h-indazole derivatives - Google Patents

Antibacterial 2h-indazole derivatives

Info

Publication number
SG11201601889YA
SG11201601889YA SG11201601889YA SG11201601889YA SG11201601889YA SG 11201601889Y A SG11201601889Y A SG 11201601889YA SG 11201601889Y A SG11201601889Y A SG 11201601889YA SG 11201601889Y A SG11201601889Y A SG 11201601889YA SG 11201601889Y A SG11201601889Y A SG 11201601889YA
Authority
SG
Singapore
Prior art keywords
antibacterial
indazole derivatives
indazole
derivatives
Prior art date
Application number
SG11201601889YA
Inventor
Jean-Christophe Gauvin
Azely Mirre
Etienne Ochala
Jean-Philippe Surivet
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Publication of SG11201601889YA publication Critical patent/SG11201601889YA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56Benzopyrazoles; Hydrogenated benzopyrazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/10Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/10Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6503Five-membered rings
    • C07F9/65031Five-membered rings having the nitrogen atoms in the positions 1 and 2
    • C07F9/65038Five-membered rings having the nitrogen atoms in the positions 1 and 2 condensed with carbocyclic rings or carbocyclic ring systems
SG11201601889YA 2013-09-13 2014-09-12 Antibacterial 2h-indazole derivatives SG11201601889YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB2013058537 2013-09-13
PCT/IB2014/064458 WO2015036964A1 (en) 2013-09-13 2014-09-12 Antibacterial 2h-indazole derivatives

Publications (1)

Publication Number Publication Date
SG11201601889YA true SG11201601889YA (en) 2016-04-28

Family

ID=51688371

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201601889YA SG11201601889YA (en) 2013-09-13 2014-09-12 Antibacterial 2h-indazole derivatives

Country Status (29)

Country Link
US (1) US9802901B2 (en)
EP (1) EP3044211B1 (en)
JP (1) JP6353909B2 (en)
KR (1) KR20160055889A (en)
CN (1) CN105531264B (en)
AR (1) AR097617A1 (en)
AU (1) AU2014319966B2 (en)
BR (1) BR112016007757A8 (en)
CA (1) CA2923146A1 (en)
CL (1) CL2016000568A1 (en)
CY (1) CY1120111T1 (en)
DK (1) DK3044211T3 (en)
EA (1) EA031562B1 (en)
ES (1) ES2662894T3 (en)
HR (1) HRP20180484T1 (en)
HU (1) HUE038519T2 (en)
IL (1) IL244500B (en)
LT (1) LT3044211T (en)
MA (1) MA38948B1 (en)
MX (1) MX361733B (en)
MY (1) MY179283A (en)
PH (1) PH12016500480B1 (en)
PL (1) PL3044211T3 (en)
PT (1) PT3044211T (en)
SG (1) SG11201601889YA (en)
SI (1) SI3044211T1 (en)
TW (1) TWI646084B (en)
UA (1) UA116484C2 (en)
WO (1) WO2015036964A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6407288B2 (en) 2013-12-19 2018-10-17 イドーシア ファーマシューティカルズ リミテッドIdorsia Pharmaceuticals Ltd Antibacterial 1H-indazole and 1H-indole derivatives
AR099612A1 (en) 2014-03-04 2016-08-03 Actelion Pharmaceuticals Ltd ANTIBACTERIAL DERIVATIVES OF 1,2-DIHIDRO-3H-PIRROLO [1,2-C] IMIDAZOL-3-ONA
EP3143007B1 (en) 2014-05-16 2018-07-11 Idorsia Pharmaceuticals Ltd Antibacterial quinazoline-4(3h)-one derivatives
CA2963875A1 (en) 2014-11-19 2016-05-26 Actelion Pharmaceuticals Ltd Antibacterial benzothiazole derivatives
AR105646A1 (en) 2015-08-11 2017-10-25 Actelion Pharmaceuticals Ltd ANTIBACTERIAL AGENTS OF 1,2-DIHIDRO-3H-PIRROLO [1,2-C] IMIDAZOL-3-ONA SUBSTITUTED
EP3341378A1 (en) * 2015-08-28 2018-07-04 Idorsia Pharmaceuticals Ltd Antibacterial annulated pyrrolidin-2-one derivatives
AR105848A1 (en) * 2015-08-31 2017-11-15 Actelion Pharmaceuticals Ltd ANTIBACTERIAL HETEROCYCLIC DERIVATIVES
AR105889A1 (en) * 2015-09-03 2017-11-22 Actelion Pharmaceuticals Ltd ANTIBACTERIAL COMPOUNDS 1,2-DIHIDRO-3H-PIRROLO [1,2-C] IMIDAZOL-3-ONA SUBSTITUTED
BR112018073580A2 (en) * 2016-05-17 2019-03-19 Idorsia Pharmaceuticals Ltd 6- (buta-1,3-diyn-1-yl) benzo [d] thiazole derivatives
WO2019038362A1 (en) 2017-08-24 2019-02-28 Idorsia Pharmaceuticals Ltd Antibacterial pyrroloimidazolones
CN113372276B (en) * 2021-05-25 2022-04-22 三峡大学 Indazole derivative and application thereof

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2004117082A (en) 2001-12-05 2005-04-10 Орто-Макнейл Фармасьютикал, Инк. (Us) KETOLIDE 6-0-ACYL DERIVATIVES OF ERYTHROMYCIN AS ANTIBACTERIAL MEANS
US6806279B2 (en) 2001-12-17 2004-10-19 Sunesis Pharmaceuticals, Inc. Small-molecule inhibitors of interleukin-2
SG148857A1 (en) 2002-03-13 2009-01-29 Array Biopharma Inc N3 alkylated benzimidazole derivatives as mek inhibitors
DE102004017930A1 (en) 2004-04-14 2005-11-03 Boehringer Ingelheim Pharma Gmbh & Co. Kg New alkyne compounds having MCH antagonist activity and medicaments containing these compounds
EP1828145A4 (en) 2004-12-10 2009-08-19 Univ Emory 2' and 3' - substituted cyclobutyl nucleoside analogs for the treatment of viral infections and abnormal cellular proliferation
KR100968989B1 (en) 2005-03-23 2010-07-09 에프. 호프만-라 로슈 아게 Acetylenyl-pyrazolo-pyrimidine derivatives as mglur2 antagonists
EP2662353A3 (en) 2007-06-12 2014-04-02 Achaogen, Inc. Antibacterial agents
DE102008044132A1 (en) 2008-11-27 2010-06-02 BSH Bosch und Siemens Hausgeräte GmbH Refrigerating appliance with double-sided door
WO2010100475A1 (en) 2009-03-02 2010-09-10 Astrazeneca Ab Hydroxamic acid derivatives as gram-negative antibacterial agents
WO2010135536A2 (en) 2009-05-20 2010-11-25 Ardea Biosciences, Inc. Methods of modulating uric acid levels
WO2011021209A1 (en) 2009-07-07 2011-02-24 Portsmouth Technologies Llc Histone deacetylase inhibitors
US8853258B2 (en) * 2009-10-13 2014-10-07 Pfizer Inc. C-linked hydroxamic acid derivatives useful as antibacterial agents
WO2011073845A1 (en) 2009-12-16 2011-06-23 Pfizer Inc. N-linked hydroxamic acid derivatives useful as antibacterial agents
GB2483736B (en) 2010-09-16 2012-08-29 Aragon Pharmaceuticals Inc Estrogen receptor modulators and uses thereof
CN103298780A (en) 2010-11-10 2013-09-11 尔察祯有限公司 Hydroxamic acid derivatives and their use in the treatment of bacterial infections
JP2014501274A (en) 2011-01-03 2014-01-20 ハンミ ファーム. シーオー., エルティーディー. Novel bicyclic compounds for G protein coupled receptor modulation
UA107423C2 (en) * 2011-03-07 2014-12-25 Pfizer Fluoro-pyridinone derivatives useful as antibacterial agents
DK2694488T3 (en) 2011-04-08 2014-12-15 Pfizer Isoxazole derivatives useful as antibacterial SUBSTANCES
KR20130140164A (en) 2011-04-08 2013-12-23 화이자 인코포레이티드 Imidazole, pyrazole, and triazole derivatives useful as antibacterial agents
EP2847162A1 (en) 2012-05-09 2015-03-18 Achaogen, Inc. Antibacterial agents
JP6407288B2 (en) 2013-12-19 2018-10-17 イドーシア ファーマシューティカルズ リミテッドIdorsia Pharmaceuticals Ltd Antibacterial 1H-indazole and 1H-indole derivatives
AR099612A1 (en) 2014-03-04 2016-08-03 Actelion Pharmaceuticals Ltd ANTIBACTERIAL DERIVATIVES OF 1,2-DIHIDRO-3H-PIRROLO [1,2-C] IMIDAZOL-3-ONA
EP3143007B1 (en) 2014-05-16 2018-07-11 Idorsia Pharmaceuticals Ltd Antibacterial quinazoline-4(3h)-one derivatives

Also Published As

Publication number Publication date
PT3044211T (en) 2018-03-21
MA38948B1 (en) 2018-04-30
CL2016000568A1 (en) 2016-11-11
HUE038519T2 (en) 2018-10-29
EP3044211A1 (en) 2016-07-20
TWI646084B (en) 2019-01-01
IL244500A0 (en) 2016-04-21
MY179283A (en) 2020-11-03
PH12016500480A1 (en) 2016-05-16
AU2014319966B2 (en) 2018-11-15
IL244500B (en) 2018-05-31
US20160221959A1 (en) 2016-08-04
JP2016530327A (en) 2016-09-29
ES2662894T3 (en) 2018-04-10
EP3044211B1 (en) 2018-01-03
MX361733B (en) 2018-12-14
BR112016007757A8 (en) 2018-08-14
PL3044211T3 (en) 2018-06-29
HRP20180484T1 (en) 2018-05-04
TW201542531A (en) 2015-11-16
AU2014319966A1 (en) 2016-05-05
MA38948A1 (en) 2017-05-31
CN105531264B (en) 2018-04-10
PH12016500480B1 (en) 2016-05-16
CY1120111T1 (en) 2018-12-12
WO2015036964A1 (en) 2015-03-19
KR20160055889A (en) 2016-05-18
CA2923146A1 (en) 2015-03-19
SI3044211T1 (en) 2018-04-30
UA116484C2 (en) 2018-03-26
CN105531264A (en) 2016-04-27
BR112016007757A2 (en) 2018-07-10
EA201600248A1 (en) 2016-08-31
US9802901B2 (en) 2017-10-31
AR097617A1 (en) 2016-04-06
MX2016003196A (en) 2016-06-02
DK3044211T3 (en) 2018-03-12
LT3044211T (en) 2018-04-10
EA031562B1 (en) 2019-01-31
JP6353909B2 (en) 2018-07-04

Similar Documents

Publication Publication Date Title
HK1215795A1 (en) Amatoxin derivatives
SG11201506100XA (en) Pyridazinone-amides derivatives
IL244500B (en) Antibacterial 2h-indazole derivatives
HK1221459A1 (en) Antibacterial biaromatic derivatives
ZA201601333B (en) Oxoquinazolinyl-butanamide derivatives
SG11201605189YA (en) Imidazopyrazinone derivatives
HK1213566A1 (en) Novel tetrazolone derivatives
SG11201604752SA (en) Antibacterial peptide-inducing agent
HK1219903A1 (en) Antibacterial compounds
HK1221468A1 (en) Phthalazine derivatives
EP3009444A4 (en) Alpha-oxoacyl amino-caprolactam derivative
GB201306608D0 (en) Antibacterial drug derivatives
GB201306609D0 (en) Antibacterial drug derivatives
GB201301396D0 (en) Ar