SG11201600707QA - Substituted aminopyrimidine compounds and methods of use - Google Patents

Substituted aminopyrimidine compounds and methods of use

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Publication number
SG11201600707QA
SG11201600707QA SG11201600707QA SG11201600707QA SG11201600707QA SG 11201600707Q A SG11201600707Q A SG 11201600707QA SG 11201600707Q A SG11201600707Q A SG 11201600707QA SG 11201600707Q A SG11201600707Q A SG 11201600707QA SG 11201600707Q A SG11201600707Q A SG 11201600707QA
Authority
SG
Singapore
Prior art keywords
methods
aminopyrimidine compounds
substituted aminopyrimidine
substituted
compounds
Prior art date
Application number
SG11201600707QA
Inventor
Ning Xi
Liang Wang
Tingjin Wang
Original Assignee
Calitor Sciences Llc
Sunshine Lake Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Calitor Sciences Llc, Sunshine Lake Pharma Co Ltd filed Critical Calitor Sciences Llc
Publication of SG11201600707QA publication Critical patent/SG11201600707QA/en

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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/472Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
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    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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SG11201600707QA 2013-09-22 2014-09-17 Substituted aminopyrimidine compounds and methods of use SG11201600707QA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361880974P 2013-09-22 2013-09-22
US201461983444P 2014-04-23 2014-04-23
PCT/US2014/055967 WO2015042078A2 (en) 2013-09-22 2014-09-17 Substituted aminopyrimidine compounds and methods of use

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SG11201600707QA true SG11201600707QA (en) 2016-02-26

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SG11201600028YA SG11201600028YA (en) 2013-09-22 2014-09-17 Substituted aminopyrimidine compounds and methods of use
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US (4) US9657007B2 (en)
EP (2) EP3046563B1 (en)
JP (2) JP6494634B2 (en)
KR (2) KR20160060100A (en)
AU (2) AU2014321420B2 (en)
BR (1) BR112016003229A8 (en)
CA (2) CA2920059A1 (en)
MX (2) MX2016003456A (en)
MY (2) MY184292A (en)
RU (2) RU2675105C9 (en)
SG (2) SG11201600028YA (en)
WO (3) WO2015042077A1 (en)

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CN114259497A (en) * 2016-07-26 2022-04-01 江苏豪森药业集团有限公司 Pharmaceutical composition of aminopyrimidine compounds and preparation method thereof
CN108017641B (en) * 2016-11-02 2021-01-05 深圳铂立健医药有限公司 Pyrazolopyrimidine compound as PI3K inhibitor and application thereof
CN107056810B (en) * 2017-02-09 2019-04-26 广东省中医院 A kind of preparation method of Carbostyril carboxylic acid derivatives
CA3066939A1 (en) 2017-06-21 2018-12-27 SHY Therapeutics LLC Compounds that interact with the ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease
CN110003192A (en) * 2018-01-04 2019-07-12 广东东阳光药业有限公司 Substituted amino-metadiazine compound and its application method and purposes
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