SG11201509447YA - Ophthalmic nanoemulsion composition containing cyclosporine and method for preparing same - Google Patents
Ophthalmic nanoemulsion composition containing cyclosporine and method for preparing sameInfo
- Publication number
- SG11201509447YA SG11201509447YA SG11201509447YA SG11201509447YA SG11201509447YA SG 11201509447Y A SG11201509447Y A SG 11201509447YA SG 11201509447Y A SG11201509447Y A SG 11201509447YA SG 11201509447Y A SG11201509447Y A SG 11201509447YA SG 11201509447Y A SG11201509447Y A SG 11201509447YA
- Authority
- SG
- Singapore
- Prior art keywords
- composition containing
- preparing same
- nanoemulsion composition
- containing cyclosporine
- ophthalmic nanoemulsion
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/113—Multiple emulsions, e.g. oil-in-water-in-oil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20130056561 | 2013-05-20 | ||
| KR20140029939A KR101492447B1 (en) | 2013-05-20 | 2014-03-13 | Eye composition containing a cyclosporine and a method of preparing the same |
| PCT/KR2014/004489 WO2014189251A1 (en) | 2013-05-20 | 2014-05-20 | Nanoemulsion eyedrop composition containing cyclosporine and method for preparing same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201509447YA true SG11201509447YA (en) | 2016-02-26 |
Family
ID=52456659
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201509447YA SG11201509447YA (en) | 2013-05-20 | 2014-05-20 | Ophthalmic nanoemulsion composition containing cyclosporine and method for preparing same |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20160101050A1 (en) |
| EP (1) | EP3000474B1 (en) |
| JP (1) | JP6392858B2 (en) |
| KR (4) | KR101492447B1 (en) |
| CN (1) | CN105307668B (en) |
| CA (1) | CA2912180A1 (en) |
| ES (1) | ES2713326T3 (en) |
| PH (1) | PH12015502587B1 (en) |
| PL (1) | PL3000474T3 (en) |
| RU (1) | RU2683271C2 (en) |
| SG (1) | SG11201509447YA (en) |
| WO (1) | WO2014189251A1 (en) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101587412B1 (en) * | 2014-10-17 | 2016-01-21 | 주식회사 휴온스 | Ophthalmic Composition Comprising Cyclosporine and Trehalose |
| US20200237859A1 (en) | 2019-01-25 | 2020-07-30 | Newport Research, Inc. | Aqueous suspensions of cyclosporin |
| US11324800B2 (en) | 2015-01-15 | 2022-05-10 | Wellspring Ophthalmics, Inc. | Aqueous suspensions of cyclosporin |
| KR20170120161A (en) * | 2015-03-05 | 2017-10-30 | 알러간, 인코포레이티드 | Self-emulsifying drug delivery system (SEDDS) for ophthalmic drug delivery |
| CN106692052B (en) * | 2015-11-13 | 2021-03-26 | 天津金耀集团有限公司 | Cyclosporine emulsion composition for eyes |
| EP3187172A1 (en) * | 2016-01-04 | 2017-07-05 | Spherium Biomed S.L. | Cyclosporine a topical compositions |
| KR101939880B1 (en) * | 2016-06-29 | 2019-01-18 | 서울대학교산학협력단 | Hydrogel based nano emulsion for the selective labeling on cancerous lesions and manufacturing method the same |
| JOP20170147B1 (en) * | 2016-07-07 | 2021-08-17 | Salvat Lab Sa | Ophthalmic composition comprising castor oil and medium chain triglyceride |
| JP7044714B2 (en) | 2016-11-17 | 2022-03-30 | 千寿製薬株式会社 | Emulsion eye drops |
| WO2019002362A1 (en) * | 2017-06-28 | 2019-01-03 | Spherium Biomed, S.L. | Cyclosporine a topical compositions |
| US11583497B2 (en) * | 2017-11-14 | 2023-02-21 | The Schepens Eye Research Institute, Inc. | Nano-emulsion of CBFß-RUNX1 inhibitor for ocular drug delivery |
| KR102146704B1 (en) | 2018-04-13 | 2020-08-21 | 가천대학교 산학협력단 | Cyclosporin a containing microstructures for transdermal and intradermal drug delivery |
| CN110496096A (en) * | 2018-05-17 | 2019-11-26 | 何浩明 | Soluble micropin eye sticker and preparation method thereof |
| CN109010270B (en) * | 2018-09-03 | 2021-07-30 | 辅必成（上海）医药科技有限公司 | Eye lotion prepared from cationic material |
| US10933111B2 (en) * | 2019-01-08 | 2021-03-02 | Boston Biotechnology US CORP | Treating dry eye disorders |
| CN114245737A (en) * | 2019-06-11 | 2022-03-25 | 司斐股份有限公司 | Microemulsion compositions |
| CN110237233B (en) * | 2019-07-30 | 2021-01-15 | 沈阳兴齐眼药股份有限公司 | Ophthalmic pharmaceutical composition containing cyclosporine, preparation method and application thereof |
| MX2019010618A (en) | 2019-09-06 | 2021-11-30 | Sophia Holdings S A De C V | Pharmaceutical ophthalmic compositions, preparation processes, and uses thereof. |
| CA3149270A1 (en) | 2019-09-09 | 2021-03-18 | Taejoon Pharmaceutical Co., Ltd. | Nanoemulsion ophthalmic composition comprising cyclosporine and menthol, and preparation method thereof |
| KR20210087294A (en) | 2020-01-02 | 2021-07-12 | 주식회사 엘지에너지솔루션 | Apparatus and method for managing battery |
| MX2021003369A (en) * | 2021-03-22 | 2022-09-23 | Laboratorios Grin S A De C V | Triple ocular tear. |
| KR102650566B1 (en) * | 2021-12-03 | 2024-03-26 | 인제대학교 산학협력단 | Ocular nanoemulsion composition for the treatment of macular degeneration |
| WO2023139907A1 (en) * | 2022-01-24 | 2023-07-27 | 株式会社Moresco | Nanoemulsion endowed with antiseptic effect |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4839342A (en) | 1987-09-03 | 1989-06-13 | University Of Georgia Research Foundation, Inc. | Method of increasing tear production by topical administration of cyclosporin |
| US5474979A (en) | 1994-05-17 | 1995-12-12 | Allergan, Inc. | Nonirritating emulsions for sensitive tissue |
| US5660858A (en) | 1996-04-03 | 1997-08-26 | Research Triangle Pharmaceuticals | Cyclosporin emulsions |
| US7732404B2 (en) * | 1999-12-30 | 2010-06-08 | Dexcel Ltd | Pro-nanodispersion for the delivery of cyclosporin |
| US7501393B2 (en) * | 2005-07-27 | 2009-03-10 | Allergan, Inc. | Pharmaceutical compositions comprising cyclosporins |
| KR101132611B1 (en) | 2006-10-02 | 2012-04-06 | 엘지전자 주식회사 | Method of downloading a message, fowarding a message, and mobile communication terminal thereof |
| CN101244256A (en) * | 2007-02-16 | 2008-08-20 | 中国科学院上海药物研究所 | Micro/sub-micro emulsion in situ gel rubber preparation of cyclosporins A for eyes and preparation thereof |
| US20100305046A1 (en) * | 2009-06-02 | 2010-12-02 | Abbott Medical Optics Inc. | Stable cyclosporine containing ophthalmic emulsion for treating dry eyes |
| KR101008189B1 (en) | 2010-07-29 | 2011-01-17 | 에스씨바이오팜 주식회사 | Ophthalmic nano-emulsion composition containing cyclosporin for the treatment of dry-eye-syndrome |
| CN103282044B (en) * | 2010-12-28 | 2016-07-06 | 韩林制药株式会社 | The ophthalmic composition of nano-emulsion form |
| KR101063776B1 (en) * | 2011-03-16 | 2011-09-08 | 양은태 | Injection chemical anchor composition |
-
2014
- 2014-03-13 KR KR20140029939A patent/KR101492447B1/en active IP Right Grant
- 2014-05-20 PL PL14801762T patent/PL3000474T3/en unknown
- 2014-05-20 US US14/892,535 patent/US20160101050A1/en not_active Abandoned
- 2014-05-20 JP JP2016515262A patent/JP6392858B2/en active Active
- 2014-05-20 SG SG11201509447YA patent/SG11201509447YA/en unknown
- 2014-05-20 ES ES14801762T patent/ES2713326T3/en active Active
- 2014-05-20 RU RU2015154403A patent/RU2683271C2/en active
- 2014-05-20 WO PCT/KR2014/004489 patent/WO2014189251A1/en active Application Filing
- 2014-05-20 EP EP14801762.7A patent/EP3000474B1/en active Active
- 2014-05-20 CN CN201480029194.6A patent/CN105307668B/en active Active
- 2014-05-20 CA CA2912180A patent/CA2912180A1/en not_active Abandoned
-
2015
- 2015-01-19 KR KR1020150008575A patent/KR102058519B1/en active IP Right Grant
- 2015-11-16 PH PH12015502587A patent/PH12015502587B1/en unknown
-
2019
- 2019-12-17 KR KR1020190168663A patent/KR102133381B1/en active IP Right Grant
-
2020
- 2020-07-06 KR KR1020200082926A patent/KR102204221B1/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| CA2912180A1 (en) | 2014-11-27 |
| ES2713326T3 (en) | 2019-05-21 |
| JP2016519162A (en) | 2016-06-30 |
| CN105307668A (en) | 2016-02-03 |
| EP3000474A1 (en) | 2016-03-30 |
| RU2015154403A (en) | 2017-06-22 |
| CN105307668B (en) | 2019-10-01 |
| KR20200087108A (en) | 2020-07-20 |
| KR102133381B1 (en) | 2020-07-21 |
| JP6392858B2 (en) | 2018-09-19 |
| RU2683271C2 (en) | 2019-03-27 |
| EP3000474A4 (en) | 2017-01-18 |
| WO2014189251A1 (en) | 2014-11-27 |
| PH12015502587A1 (en) | 2016-02-29 |
| KR101492447B1 (en) | 2015-02-23 |
| KR102058519B1 (en) | 2019-12-23 |
| PL3000474T3 (en) | 2019-07-31 |
| KR20150014530A (en) | 2015-02-06 |
| US20160101050A1 (en) | 2016-04-14 |
| EP3000474B1 (en) | 2018-11-28 |
| PH12015502587B1 (en) | 2016-02-29 |
| KR20140136371A (en) | 2014-11-28 |
| KR102204221B1 (en) | 2021-01-18 |
| KR20200000395A (en) | 2020-01-02 |
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