SG11201507359SA - Flavivirus neutralizing antibodies and methods of use thereof - Google Patents

Flavivirus neutralizing antibodies and methods of use thereof

Info

Publication number
SG11201507359SA
SG11201507359SA SG11201507359SA SG11201507359SA SG11201507359SA SG 11201507359S A SG11201507359S A SG 11201507359SA SG 11201507359S A SG11201507359S A SG 11201507359SA SG 11201507359S A SG11201507359S A SG 11201507359SA SG 11201507359S A SG11201507359S A SG 11201507359SA
Authority
SG
Singapore
Prior art keywords
methods
neutralizing antibodies
flavivirus neutralizing
flavivirus
antibodies
Prior art date
Application number
SG11201507359SA
Inventor
Wayne A Marasco
Original Assignee
Dana Farber Cancer Inst Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51538297&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201507359S(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Dana Farber Cancer Inst Inc filed Critical Dana Farber Cancer Inst Inc
Publication of SG11201507359SA publication Critical patent/SG11201507359SA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1081—Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/524—CH2 domain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/71—Decreased effector function due to an Fc-modification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
SG11201507359SA 2013-03-15 2014-03-14 Flavivirus neutralizing antibodies and methods of use thereof SG11201507359SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361792336P 2013-03-15 2013-03-15
PCT/US2014/028310 WO2014144061A2 (en) 2013-03-15 2014-03-14 Flavivirus neutralizing antibodies and methods of use thereof

Publications (1)

Publication Number Publication Date
SG11201507359SA true SG11201507359SA (en) 2015-10-29

Family

ID=51538297

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201507359SA SG11201507359SA (en) 2013-03-15 2014-03-14 Flavivirus neutralizing antibodies and methods of use thereof

Country Status (10)

Country Link
US (3) US9822166B2 (en)
EP (3) EP4292657A3 (en)
JP (2) JP6427552B2 (en)
AU (2) AU2014227909C1 (en)
BR (1) BR112015021341B1 (en)
CA (1) CA2901358C (en)
MX (2) MX367668B (en)
PH (1) PH12015502164A1 (en)
SG (1) SG11201507359SA (en)
WO (1) WO2014144061A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9822166B2 (en) * 2013-03-15 2017-11-21 Dana-Farber Cancer Institute, Inc. Flavivirus neutralizing antibodies and methods of use thereof
WO2018010789A1 (en) * 2016-07-13 2018-01-18 Humabs Biomed Sa Novel antibodies specifically binding to zika virus epitopes and uses thereof
CN110214152A (en) 2016-10-14 2019-09-06 丹娜法伯癌症研究所公司 Modularization tetramer bispecific antibody platform
GB201704126D0 (en) * 2017-03-15 2017-04-26 Blom Nihlén Kim Andrea Vaccine
CN111787951A (en) * 2018-03-01 2020-10-16 Igm生物科学股份有限公司 IgM Fc and J chain mutations affecting IgM serum half-life
WO2019200160A1 (en) * 2018-04-11 2019-10-17 Tychan Pte. Ltd. Methods and compositions for treating yellow fever
JP7471555B2 (en) 2020-02-20 2024-04-22 国立感染症研究所長 Flavivirus cross-neutralizing antibodies and pharmaceutical compositions
RU2757488C1 (en) * 2020-11-10 2021-10-18 Федеральное бюджетное учреждение науки "Государственный научный центр вирусологии и биотехнологии "Вектор" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека (ФБУН ГНЦ ВБ "Вектор" Роспотребнадзора) UNIVERSAL RECOMBINANT pBuc VECTOR AND PLASMID GENETIC CONSTRUCTION pBuc-7B4, PROVIDING SYNTHESIS AND SECRETION OF ANTIBODY 7B4 AGAINST WEST NILE VIRUS IN ANIMAL CELLS AND OBTAINED USING THE SPECIFIED pBuc VECTOR
CN116514963B (en) * 2023-04-21 2023-09-26 中国人民解放军军事科学院军事医学研究院 Antibody FY2 for broad-spectrum recognition of flavivirus E protein and application thereof

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
FR2413974A1 (en) 1978-01-06 1979-08-03 David Bernard DRYER FOR SCREEN-PRINTED SHEETS
US4485045A (en) 1981-07-06 1984-11-27 Research Corporation Synthetic phosphatidyl cholines useful in forming liposomes
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4544545A (en) 1983-06-20 1985-10-01 Trustees University Of Massachusetts Liposomes containing modified cholesterol for organ targeting
US4676980A (en) 1985-09-23 1987-06-30 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Target specific cross-linked heteroantibodies
DE3788058T2 (en) 1986-08-28 1994-04-21 Teijin Ltd CELL TOXIC ANTIBODY COMPLEX AND METHOD FOR THE PRODUCTION THEREOF.
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
GB8823869D0 (en) 1988-10-12 1988-11-16 Medical Res Council Production of antibodies
EP0479909B1 (en) 1989-06-29 1996-10-30 Medarex, Inc. Bispecific reagents for aids therapy
US5013556A (en) 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
JP3068180B2 (en) 1990-01-12 2000-07-24 アブジェニックス インコーポレイテッド Generation of heterologous antibodies
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
ATE158021T1 (en) 1990-08-29 1997-09-15 Genpharm Int PRODUCTION AND USE OF NON-HUMAN TRANSGENT ANIMALS FOR THE PRODUCTION OF HETEROLOGUE ANTIBODIES
US5661016A (en) 1990-08-29 1997-08-26 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
US5625126A (en) 1990-08-29 1997-04-29 Genpharm International, Inc. Transgenic non-human animals for producing heterologous antibodies
US5633425A (en) 1990-08-29 1997-05-27 Genpharm International, Inc. Transgenic non-human animals capable of producing heterologous antibodies
EP0586505A1 (en) 1991-05-14 1994-03-16 Repligen Corporation Heteroconjugate antibodies for treatment of hiv infection
EP0604415A1 (en) 1991-09-17 1994-07-06 European Economic Community E.E.C. Electron detector device for spectroscopic analyses of surfaces under x-ray excitation
US5233409A (en) 1992-02-25 1993-08-03 Schwab Karl W Color analysis of organic constituents in sedimentary rocks for thermal maturity
ES2301158T3 (en) 1992-07-24 2008-06-16 Amgen Fremont Inc. XENOGENIC ANTIBODY PRODUCTION.
WO1994011026A2 (en) 1992-11-13 1994-05-26 Idec Pharmaceuticals Corporation Therapeutic application of chimeric and radiolabeled antibodies to human b lymphocyte restricted differentiation antigen for treatment of b cell lymphoma
JPH10501681A (en) 1994-02-22 1998-02-17 ダナ−ファーバー キャンサー インスティチュート Nucleic acid delivery systems and methods for their synthesis and use
CA2761116A1 (en) 1995-04-27 1996-10-31 Amgen Fremont Inc. Human antibodies derived from immunized xenomice
CA2219486A1 (en) 1995-04-28 1996-10-31 Abgenix, Inc. Human antibodies derived from immunized xenomice
US5916771A (en) 1996-10-11 1999-06-29 Abgenix, Inc. Production of a multimeric protein by cell fusion method
US20020029391A1 (en) 1998-04-15 2002-03-07 Claude Geoffrey Davis Epitope-driven human antibody production and gene expression profiling
UA89481C2 (en) * 2003-09-30 2010-02-10 Центокор, Инк. Human epo mimetic hinge core mimetibodies, compositions, methods and uses
US20090130123A1 (en) * 2004-06-15 2009-05-21 Erol Fikrig Antibodies to west nile virus polypeptides
WO2010043977A2 (en) 2008-10-13 2010-04-22 Institute For Research In Biomedicine Dengue virus neutralizing antibodies and uses thereof
US20110165122A1 (en) * 2009-11-10 2011-07-07 The Regents Of The University Of California Method for targeted and sustained antiviral therapy
MX354359B (en) 2011-03-29 2018-02-28 Roche Glycart Ag Antibody fc variants.
US9822166B2 (en) * 2013-03-15 2017-11-21 Dana-Farber Cancer Institute, Inc. Flavivirus neutralizing antibodies and methods of use thereof
US9111624B2 (en) 2013-03-22 2015-08-18 Katsuyuki Fujita Semiconductor memory device

Also Published As

Publication number Publication date
EP3689902B1 (en) 2023-06-28
US20180251531A1 (en) 2018-09-06
MX2015013232A (en) 2015-12-11
US9822166B2 (en) 2017-11-21
WO2014144061A2 (en) 2014-09-18
WO2014144061A9 (en) 2014-12-11
CA2901358C (en) 2022-07-26
EP2971042A2 (en) 2016-01-20
AU2018204011B2 (en) 2019-08-29
AU2014227909C1 (en) 2021-11-25
EP4292657A2 (en) 2023-12-20
EP2971042A4 (en) 2016-09-07
US20200062830A1 (en) 2020-02-27
EP3689902A1 (en) 2020-08-05
BR112015021341B1 (en) 2023-03-28
EP2971042B1 (en) 2020-01-15
AU2018204011A1 (en) 2018-06-21
JP6427552B2 (en) 2018-11-21
AU2014227909B2 (en) 2018-03-08
PH12015502164B1 (en) 2016-01-25
MX367668B (en) 2019-08-30
AU2014227909A1 (en) 2015-08-27
BR112015021341A2 (en) 2017-07-18
JP2019054796A (en) 2019-04-11
MX2019010339A (en) 2019-10-14
JP2016514675A (en) 2016-05-23
AU2018204011C1 (en) 2021-11-25
JP6734902B2 (en) 2020-08-05
EP4292657A3 (en) 2024-03-20
US10899825B2 (en) 2021-01-26
US10400032B2 (en) 2019-09-03
CA2901358A1 (en) 2014-09-18
PH12015502164A1 (en) 2016-01-25
US20160024189A1 (en) 2016-01-28

Similar Documents

Publication Publication Date Title
IL280155A (en) Anti-siglec-8 antibodies and methods of use thereof
IL290547A (en) Antibodies and methods of use
IL244495A0 (en) Anti-alpha-synuclein antibodies and methods of use
ZA201603308B (en) Novel anti-claudin antibodies and methods of use
IL245946A0 (en) Novel anti-dpep3 antibodies and methods of use
HK1225612A1 (en) Anti-ly6e antibodies and methods of use
EP2999474A4 (en) Therapeutic and method of use
SG11201507359SA (en) Flavivirus neutralizing antibodies and methods of use thereof
HK1221641A1 (en) Vaccine composition and method of use
EP2988778A4 (en) Clostridium difficile vaccine and methods of use