SG11201507141SA - Antisense molecules for treatment of staphylococcus aureus infection - Google Patents
Antisense molecules for treatment of staphylococcus aureus infectionInfo
- Publication number
- SG11201507141SA SG11201507141SA SG11201507141SA SG11201507141SA SG11201507141SA SG 11201507141S A SG11201507141S A SG 11201507141SA SG 11201507141S A SG11201507141S A SG 11201507141SA SG 11201507141S A SG11201507141S A SG 11201507141SA SG 11201507141S A SG11201507141S A SG 11201507141SA
- Authority
- SG
- Singapore
- Prior art keywords
- treatment
- staphylococcus aureus
- antisense molecules
- aureus infection
- infection
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
- C12N2310/111—Antisense spanning the whole gene, or a large part of it
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/31—Chemical structure of the backbone
- C12N2310/318—Chemical structure of the backbone where the PO2 is completely replaced, e.g. MMI or formacetal
- C12N2310/3181—Peptide nucleic acid, PNA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/35—Nature of the modification
- C12N2310/351—Conjugate
- C12N2310/3513—Protein; Peptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/30—Special therapeutic applications
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361786926P | 2013-03-15 | 2013-03-15 | |
| PCT/US2014/028830 WO2014144423A2 (en) | 2013-03-15 | 2014-03-14 | Antisense molecules for treatment of staphylococcus aureus infection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201507141SA true SG11201507141SA (en) | 2015-10-29 |
Family
ID=51538325
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201507141SA SG11201507141SA (en) | 2013-03-15 | 2014-03-14 | Antisense molecules for treatment of staphylococcus aureus infection |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US9909123B2 (en) |
| EP (1) | EP2970976A4 (en) |
| JP (1) | JP2016515381A (en) |
| KR (1) | KR20160021076A (en) |
| CA (1) | CA2906663A1 (en) |
| IL (1) | IL241226A0 (en) |
| SG (1) | SG11201507141SA (en) |
| WO (1) | WO2014144423A2 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102206573B1 (en) | 2013-03-15 | 2021-01-25 | 테출론 인코포레이티드 | Antisense molecules for treatment of staphylococcus aureus infection |
| US20200325178A1 (en) * | 2017-11-01 | 2020-10-15 | Techulon Inc. | Peptide nucleic acid molecules for treatment of gram positive bacterial infection |
| WO2019232059A1 (en) * | 2018-05-29 | 2019-12-05 | Techulon Inc. | Antisense oligonucleotides for the treatment of p. aeruginsoa, a. baumannii and k. pneumoniae infections |
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| US8211468B2 (en) | 1999-06-07 | 2012-07-03 | Arrowhead Madison Inc. | Endosomolytic polymers |
| AU2041901A (en) | 1999-11-09 | 2001-06-06 | Elitra Pharmaceuticals, Inc. | Genes essential for microbial proliferation and antisense thereto |
| AU2001282860A1 (en) | 2000-07-19 | 2002-02-05 | Pharmacia And Upjohn Company | Staphylococcus aureus ribosomal protein s20, corresponding gene and methods for the identification of antibacterial substances |
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| US20080242627A1 (en) | 2000-08-02 | 2008-10-02 | University Of Southern California | Novel rna interference methods using dna-rna duplex constructs |
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| BR112015009138A2 (en) * | 2012-10-23 | 2020-10-20 | Caris Life Sciences Switzerland Holdings, S.A.R.L. | methods for characterizing cancer |
| KR102206573B1 (en) | 2013-03-15 | 2021-01-25 | 테출론 인코포레이티드 | Antisense molecules for treatment of staphylococcus aureus infection |
| WO2014197091A2 (en) | 2013-03-15 | 2014-12-11 | Techulon Inc. | Rapidly adaptable nano therapeutics for treatment of infectious disease |
-
2014
- 2014-03-14 WO PCT/US2014/028830 patent/WO2014144423A2/en active Application Filing
- 2014-03-14 KR KR1020157028890A patent/KR20160021076A/en not_active Application Discontinuation
- 2014-03-14 EP EP14764378.7A patent/EP2970976A4/en not_active Withdrawn
- 2014-03-14 JP JP2016502912A patent/JP2016515381A/en active Pending
- 2014-03-14 SG SG11201507141SA patent/SG11201507141SA/en unknown
- 2014-03-14 US US14/777,007 patent/US9909123B2/en active Active
- 2014-03-14 CA CA2906663A patent/CA2906663A1/en not_active Abandoned
-
2015
- 2015-09-06 IL IL241226A patent/IL241226A0/en unknown
-
2018
- 2018-01-03 US US15/860,843 patent/US20180362976A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014144423A3 (en) | 2014-11-13 |
| US9909123B2 (en) | 2018-03-06 |
| US20180362976A1 (en) | 2018-12-20 |
| WO2014144423A2 (en) | 2014-09-18 |
| IL241226A0 (en) | 2015-11-30 |
| EP2970976A2 (en) | 2016-01-20 |
| US20160177297A1 (en) | 2016-06-23 |
| JP2016515381A (en) | 2016-05-30 |
| KR20160021076A (en) | 2016-02-24 |
| CA2906663A1 (en) | 2014-09-18 |
| EP2970976A4 (en) | 2016-11-02 |
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