SG11201506624SA - A process for the production of adenovirus - Google Patents

A process for the production of adenovirus

Info

Publication number
SG11201506624SA
SG11201506624SA SG11201506624SA SG11201506624SA SG11201506624SA SG 11201506624S A SG11201506624S A SG 11201506624SA SG 11201506624S A SG11201506624S A SG 11201506624SA SG 11201506624S A SG11201506624S A SG 11201506624SA SG 11201506624S A SG11201506624S A SG 11201506624SA
Authority
SG
Singapore
Prior art keywords
adenovirus
production
Prior art date
Application number
SG11201506624SA
Inventor
Kerry Fisher
Jeetendra Bhatia
Brian Robert Champion
Original Assignee
Psioxus Therapuetics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Psioxus Therapuetics Ltd filed Critical Psioxus Therapuetics Ltd
Publication of SG11201506624SA publication Critical patent/SG11201506624SA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/76—Viruses; Subviral particles; Bacteriophages
    • A61K35/761—Adenovirus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10032—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10051—Methods of production or purification of viral material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10051—Methods of production or purification of viral material
    • C12N2710/10052—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10332—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10351—Methods of production or purification of viral material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SG11201506624SA 2013-02-28 2014-02-28 A process for the production of adenovirus SG11201506624SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361770513P 2013-02-28 2013-02-28
PCT/EP2014/053987 WO2014131898A1 (en) 2013-02-28 2014-02-28 A process for the production of adenovirus

Publications (1)

Publication Number Publication Date
SG11201506624SA true SG11201506624SA (en) 2015-09-29

Family

ID=50390048

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201706863SA SG10201706863SA (en) 2013-02-28 2014-02-28 A process for the production of adenovirus
SG11201506624SA SG11201506624SA (en) 2013-02-28 2014-02-28 A process for the production of adenovirus

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG10201706863SA SG10201706863SA (en) 2013-02-28 2014-02-28 A process for the production of adenovirus

Country Status (13)

Country Link
US (1) US20160090574A1 (en)
EP (1) EP2961417A1 (en)
JP (1) JP2016509836A (en)
KR (1) KR20150122674A (en)
CN (1) CN105189739A (en)
AU (1) AU2014222610A1 (en)
BR (1) BR112015021297A2 (en)
CA (1) CA2902650A1 (en)
HK (1) HK1218507A1 (en)
IL (1) IL240748A0 (en)
RU (1) RU2015135473A (en)
SG (2) SG10201706863SA (en)
WO (1) WO2014131898A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014153204A1 (en) 2013-03-14 2014-09-25 Salk Institute For Biological Studies Oncolytic adenovirus compositions
GB201415579D0 (en) * 2014-09-03 2014-10-15 Psioxus Therapeutics Ltd A process
WO2016030489A2 (en) * 2014-08-27 2016-03-03 Psioxus Therapeutics Limited A process for the production of adenovirus
CN104958324A (en) 2015-05-29 2015-10-07 黄波 Oncolytic virus preparation and preparing method thereof
EP3390428B1 (en) 2016-02-23 2019-09-25 Salk Institute for Biological Studies High throughput assay for measuring adenovirus replication kinetics
KR20220163505A (en) 2016-02-23 2022-12-09 솔크 인스티튜트 포 바이올로지칼 스터디즈 Exogenous gene expression in therapeutic adenovirus for minimal impact on viral kinetics
EP3532082A4 (en) 2016-12-12 2020-08-26 Salk Institute for Biological Studies Tumor-targeting synthetic adenoviruses and uses thereof
PL3630143T3 (en) * 2017-06-01 2023-10-30 Akamis Bio Limited Oncolytic virus and method
GB201909081D0 (en) * 2019-06-25 2019-08-07 Psioxus Therapeutics Ltd Method
CN110894494B (en) * 2019-11-22 2022-09-27 广西梧州制药（集团）股份有限公司 Method for large-scale high-density suspension culture of 293 cell high-yield adenovirus

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9710030A (en) * 1996-07-01 1999-08-10 Rhone Poulenc Rorer Sa Process of production of recombinant adenoviruses process of purification of recombinant adenoviruses from a biological medium purified viral preparation pharmaceutical composition and use of iodixanol-5,5 '- [(2-Hydroxypropyl-1,3-Propanottl) -Bis [N, N'-Bis (2,3-Didroxypropyl-2,4,6-Triodo-1,3-Benzenocarboxamide]
JP2007522814A (en) * 2004-02-23 2007-08-16 クルセル ホランド ベー ヴェー Virus purification method
CN102816742B (en) * 2004-05-26 2014-04-09 普西奥克瑟斯医疗有限公司 Chimeric adenoviruses for use in cancer treatment
CA2673520A1 (en) 2006-12-22 2008-07-03 Bayer Schering Pharma Aktiengesellschaft Generation of oncolytic adenoviruses and uses thereof
CN101235365A (en) * 2007-01-31 2008-08-06 深圳市清华源兴生物医药科技有限公司 Highly effective method for producing adenovirus
DK2488635T3 (en) 2009-10-15 2014-02-24 Crucell Holland Bv A method for purifying adenovirus of cultures with high cell density

Also Published As

Publication number Publication date
RU2015135473A (en) 2017-03-31
EP2961417A1 (en) 2016-01-06
KR20150122674A (en) 2015-11-02
CN105189739A (en) 2015-12-23
WO2014131898A1 (en) 2014-09-04
BR112015021297A2 (en) 2017-10-10
AU2014222610A1 (en) 2015-10-15
HK1218507A1 (en) 2017-02-24
US20160090574A1 (en) 2016-03-31
IL240748A0 (en) 2015-10-29
CA2902650A1 (en) 2014-09-04
JP2016509836A (en) 2016-04-04
SG10201706863SA (en) 2017-10-30

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