SG11201505866RA - In vitro differentiation of pluripotent stem cells to pancreatic endoderm cells (pec) and endocrine cells - Google Patents
In vitro differentiation of pluripotent stem cells to pancreatic endoderm cells (pec) and endocrine cellsInfo
- Publication number
- SG11201505866RA SG11201505866RA SG11201505866RA SG11201505866RA SG11201505866RA SG 11201505866R A SG11201505866R A SG 11201505866RA SG 11201505866R A SG11201505866R A SG 11201505866RA SG 11201505866R A SG11201505866R A SG 11201505866RA SG 11201505866R A SG11201505866R A SG 11201505866RA
- Authority
- SG
- Singapore
- Prior art keywords
- cells
- pec
- pluripotent stem
- pancreatic endoderm
- vitro differentiation
- Prior art date
Links
- 230000004069 differentiation Effects 0.000 title 1
- 210000003890 endocrine cell Anatomy 0.000 title 1
- 210000004039 endoderm cell Anatomy 0.000 title 1
- 238000000338 in vitro Methods 0.000 title 1
- 210000001778 pluripotent stem cell Anatomy 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
- A61K35/39—Pancreas; Islets of Langerhans
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
- A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0012—Cell encapsulation
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0676—Pancreatic cells
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- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0676—Pancreatic cells
- C12N5/0678—Stem cells; Progenitor cells; Precursor cells
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- C12N2501/727—Kinases (EC 2.7.)
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
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- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361781005P | 2013-03-14 | 2013-03-14 | |
US14/106,330 US8859286B2 (en) | 2013-03-14 | 2013-12-13 | In vitro differentiation of pluripotent stem cells to pancreatic endoderm cells (PEC) and endocrine cells |
PCT/US2014/026529 WO2014160413A1 (en) | 2013-03-14 | 2014-03-13 | In vitro differentiation of pluripotent stem cells to pancreatic endoderm cells (pec) and endocrine cells |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201505866RA true SG11201505866RA (en) | 2015-08-28 |
Family
ID=51527928
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201505866RA SG11201505866RA (en) | 2013-03-14 | 2014-03-13 | In vitro differentiation of pluripotent stem cells to pancreatic endoderm cells (pec) and endocrine cells |
SG10201610787XA SG10201610787XA (en) | 2013-03-14 | 2014-03-13 | In vitro differentiation of pluripotent stem cells to pancreatic endoderm cells (pec) and endocrine cells |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201610787XA SG10201610787XA (en) | 2013-03-14 | 2014-03-13 | In vitro differentiation of pluripotent stem cells to pancreatic endoderm cells (pec) and endocrine cells |
Country Status (12)
Country | Link |
---|---|
US (5) | US8859286B2 (en) |
EP (2) | EP2970899B1 (en) |
JP (6) | JP6219494B2 (en) |
KR (6) | KR102077367B1 (en) |
AU (6) | AU2014243791B2 (en) |
CA (2) | CA3204013A1 (en) |
DK (1) | DK2970899T3 (en) |
ES (1) | ES2739082T3 (en) |
IL (3) | IL294691A (en) |
RU (3) | RU2734657C2 (en) |
SG (2) | SG11201505866RA (en) |
WO (1) | WO2014160413A1 (en) |
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