SG11201505110YA - Enzymatic transesterification/esterification processing systems and processes employing lipases immobilized on hydrophobic resins - Google Patents

Enzymatic transesterification/esterification processing systems and processes employing lipases immobilized on hydrophobic resins

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Publication number
SG11201505110YA
SG11201505110YA SG11201505110YA SG11201505110YA SG11201505110YA SG 11201505110Y A SG11201505110Y A SG 11201505110YA SG 11201505110Y A SG11201505110Y A SG 11201505110YA SG 11201505110Y A SG11201505110Y A SG 11201505110YA SG 11201505110Y A SG11201505110Y A SG 11201505110YA
Authority
SG
Singapore
Prior art keywords
processing systems
processes employing
hydrophobic resins
enzymatic transesterification
lipases immobilized
Prior art date
Application number
SG11201505110YA
Inventor
Sobhi Basheer
Usama Mohsen
Original Assignee
Trans Bio Diesel Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trans Bio Diesel Ltd filed Critical Trans Bio Diesel Ltd
Publication of SG11201505110YA publication Critical patent/SG11201505110YA/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/18—Apparatus specially designed for the use of free, immobilized or carrier-bound enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/58—Reaction vessels connected in series or in parallel
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/02—Membranes; Filters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/16—Particles; Beads; Granular material; Encapsulation
    • C12M25/20—Fluidized bed
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/02—Stirrer or mobile mixing elements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/18—External loop; Means for reintroduction of fermented biomass or liquid percolate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C12M41/18—Heat exchange systems, e.g. heat jackets or outer envelopes
    • C12M41/22—Heat exchange systems, e.g. heat jackets or outer envelopes in contact with the bioreactor walls
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/44—Means for regulation, monitoring, measurement or control, e.g. flow regulation of volume or liquid level
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/10—Separation or concentration of fermentation products
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6458—Glycerides by transesterification, e.g. interesterification, ester interchange, alcoholysis or acidolysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/649—Biodiesel, i.e. fatty acid alkyl esters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/01—Carboxylic ester hydrolases (3.1.1)
    • C12Y301/01003—Triacylglycerol lipase (3.1.1.3)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Thermal Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Clinical Laboratory Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
SG11201505110YA 2012-12-31 2013-12-30 Enzymatic transesterification/esterification processing systems and processes employing lipases immobilized on hydrophobic resins SG11201505110YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261747618P 2012-12-31 2012-12-31
PCT/IL2013/051079 WO2014102796A1 (en) 2012-12-31 2013-12-30 Enzymatic transesterification/esterification processing systems and processes employing lipases immobilized on hydrophobic resins

Publications (1)

Publication Number Publication Date
SG11201505110YA true SG11201505110YA (en) 2015-07-30

Family

ID=51017605

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201505110YA SG11201505110YA (en) 2012-12-31 2013-12-30 Enzymatic transesterification/esterification processing systems and processes employing lipases immobilized on hydrophobic resins

Country Status (16)

Country Link
US (3) US20150353970A1 (en)
EP (1) EP2938739A4 (en)
JP (1) JP6430960B2 (en)
KR (1) KR20150102034A (en)
CN (1) CN104884630A (en)
AR (1) AR094350A1 (en)
AU (1) AU2013368822B2 (en)
CA (1) CA2896428C (en)
CL (1) CL2015001836A1 (en)
HK (1) HK1211987A1 (en)
MX (1) MX2015008523A (en)
PE (1) PE20151447A1 (en)
RU (1) RU2015126914A (en)
SG (1) SG11201505110YA (en)
TW (1) TW201432050A (en)
WO (1) WO2014102796A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101684455B1 (en) * 2013-07-30 2016-12-08 한국생명공학연구원 A reactor for continuous biodiesel production using immobilized enzyme and method thereof
CN113913475A (en) * 2015-10-09 2022-01-11 诺维信公司 Enzyme or non-enzyme biodiesel refining method
KR101716219B1 (en) * 2016-07-05 2017-03-20 주식회사 비츠로테크 Bio diesel reaction device
KR101957585B1 (en) * 2016-09-23 2019-03-14 씨제이제일제당 (주) A fatty acid ethyl ester for cosmetics
AU2017383551B2 (en) * 2016-12-19 2022-01-27 Enzymocore Ltd. Enzymatic enrichment of n-3 fatty acids in the form of glycerides
EP3875594A4 (en) * 2018-10-30 2022-05-18 Wuhan Wuyao Pharmaceutical Co., Ltd. Preparation method for (r)-o-chloromandelic acid and cyclic bioenzyme catalytic reaction system for the preparation method
KR102307780B1 (en) * 2019-02-21 2021-10-05 고려대학교 산학협력단 Immobilized lipase for diisononyl adipate synthesis, preparation method of thereof, and preparation method of diisononyl adipate using thereof
WO2020200879A1 (en) * 2019-04-04 2020-10-08 Universiteit Gent A continuous flow process for the preparation of sugar esters
CN113684126B (en) * 2021-10-26 2022-02-15 华南理工大学 Device and method for continuously synthesizing diglyceride by holoenzyme method in multi-liquid-phase system
WO2024089298A1 (en) 2022-10-24 2024-05-02 Selabtec Sciences, Slu Method for preparing a biofuel composition

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NL7709179A (en) * 1977-08-19 1979-02-21 Stamicarbon METHOD OF PERFORMING ENZYMATIC CONVERSIONS.
IE54838B1 (en) * 1982-04-30 1990-02-28 Unilever Plc Improvements in and relating to interesterification of triglycerides of fatty acids
JP3604715B2 (en) * 1993-09-07 2004-12-22 サッポロホールディングス株式会社 Alcohol production method
WO1997001632A1 (en) 1995-06-27 1997-01-16 Unilever N.V. Immobilized enzyme and its use for the processing of triglyceride oils
CN1279174C (en) * 2002-05-10 2006-10-11 北京化工大学 Fixed lipase catalyzed synthesis of fatty acid low carbon alcohol ester
US7473539B2 (en) 2004-09-20 2009-01-06 Sunho Biodiesel Corporation Methods for producing alkyl esters
EP1840203A1 (en) * 2006-03-31 2007-10-03 Cargill, Inc. Enzymatic modification in a continuously regenerated packed bed column
PT2059550E (en) * 2006-08-30 2011-12-15 Basf Se Method for producing polyesterols
IL180598A0 (en) 2007-01-08 2007-07-04 Basheer Sobhi Immobilized interfacial enzymes of improved and stabilized activity
IL183084A0 (en) 2007-05-09 2007-09-20 Trans Biodisel Ltd Modified-immobilized enzymes of high tolerance to hydrophilic substrates in organic media
US8617866B2 (en) 2007-11-28 2013-12-31 Sobhi Basheer Robust multi-enzyme preparation for the synthesis of fatty acid alkyl esters
US7790429B2 (en) 2007-11-28 2010-09-07 Transbiodiesel Ltd. Robust multi-enzyme preparation for the synthesis of fatty acid alkyl esters
CN102272317A (en) * 2008-10-31 2011-12-07 诺维信公司 Enzymatic production of fatty acid ethyl esters
US10000731B2 (en) 2010-03-01 2018-06-19 Trans Bio-Diesel Ltd. Enzymatic transesterification/esterification processes employing lipases immobilized on hydrophobic resins in the presence of water solutions
WO2013030816A1 (en) * 2011-08-31 2013-03-07 Trans Bio-Diesel Ltd. Enzymatic transesterification with lipases immobilized on hydrophobic resins in water solutions
WO2011107977A1 (en) 2010-03-01 2011-09-09 Trans Bio-Diesel Ltd. A process for the enzymatic synthesis of fatty acid alkyl esters

Also Published As

Publication number Publication date
KR20150102034A (en) 2015-09-04
AR094350A1 (en) 2015-07-29
US20150353970A1 (en) 2015-12-10
HK1211987A1 (en) 2016-06-03
US20140186908A1 (en) 2014-07-03
RU2015126914A (en) 2017-02-02
US10280389B2 (en) 2019-05-07
AU2013368822B2 (en) 2017-04-20
MX2015008523A (en) 2015-09-10
EP2938739A1 (en) 2015-11-04
CA2896428C (en) 2017-07-18
WO2014102796A1 (en) 2014-07-03
CN104884630A (en) 2015-09-02
EP2938739A4 (en) 2016-07-27
US20170166850A1 (en) 2017-06-15
PE20151447A1 (en) 2015-10-14
CL2015001836A1 (en) 2015-11-27
JP6430960B2 (en) 2018-11-28
JP2016503652A (en) 2016-02-08
AU2013368822A1 (en) 2015-07-09
CA2896428A1 (en) 2014-07-03
TW201432050A (en) 2014-08-16

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