SG11201503942RA - Egfr and c-met-fibronectin type iii domain binding molecules - Google Patents

Egfr and c-met-fibronectin type iii domain binding molecules

Info

Publication number
SG11201503942RA
SG11201503942RA SG11201503942RA SG11201503942RA SG11201503942RA SG 11201503942R A SG11201503942R A SG 11201503942RA SG 11201503942R A SG11201503942R A SG 11201503942RA SG 11201503942R A SG11201503942R A SG 11201503942RA SG 11201503942R A SG11201503942R A SG 11201503942RA
Authority
SG
Singapore
Prior art keywords
egfr
met
binding molecules
type iii
fibronectin type
Prior art date
Application number
SG11201503942RA
Inventor
Mark Anderson
Ricardo Attar
Michael Diem
Linus Hyun
Steven Jacobs
Alastair King
Donna Klein
Sheri Moores
Karyn O'neil
Kristen Picha
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50776675&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201503942R(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of SG11201503942RA publication Critical patent/SG11201503942RA/en

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2318/00Antibody mimetics or scaffolds
    • C07K2318/20Antigen-binding scaffold molecules wherein the scaffold is not an immunoglobulin variable region or antibody mimetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
SG11201503942RA 2012-11-21 2013-11-21 Egfr and c-met-fibronectin type iii domain binding molecules SG11201503942RA (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201261728914P 2012-11-21 2012-11-21
US201261728912P 2012-11-21 2012-11-21
US201261728906P 2012-11-21 2012-11-21
US201361782550P 2013-03-14 2013-03-14
US201361809541P 2013-04-08 2013-04-08
PCT/US2013/071267 WO2014081944A2 (en) 2012-11-21 2013-11-21 Egfr and c-met-fibronectin type iii domain binding molecules

Publications (1)

Publication Number Publication Date
SG11201503942RA true SG11201503942RA (en) 2015-06-29

Family

ID=50776675

Family Applications (2)

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SG10201707488TA SG10201707488TA (en) 2012-11-21 2013-11-21 Egfr and c-met-fibronectin type iii domain binding molecules
SG11201503942RA SG11201503942RA (en) 2012-11-21 2013-11-21 Egfr and c-met-fibronectin type iii domain binding molecules

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG10201707488TA SG10201707488TA (en) 2012-11-21 2013-11-21 Egfr and c-met-fibronectin type iii domain binding molecules

Country Status (21)

Country Link
US (4) US9695228B2 (en)
EP (3) EP2922566B1 (en)
JP (3) JP6393270B2 (en)
KR (2) KR102210196B1 (en)
CN (5) CN108546300B (en)
AU (3) AU2013347952B2 (en)
CA (1) CA2891485A1 (en)
CL (1) CL2015001353A1 (en)
EA (2) EA035559B1 (en)
ES (2) ES2696148T3 (en)
HK (1) HK1215680A1 (en)
IL (2) IL238730B (en)
MX (2) MX369334B (en)
MY (1) MY176820A (en)
NI (1) NI201500070A (en)
NZ (1) NZ708349A (en)
PH (1) PH12015501134A1 (en)
SG (2) SG10201707488TA (en)
UA (1) UA118096C2 (en)
WO (1) WO2014081944A2 (en)
ZA (1) ZA201504427B (en)

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CN108546300B (en) 2022-03-15
CN107098975A (en) 2017-08-29
CN104955473A (en) 2015-09-30
MX2019013117A (en) 2019-12-16
EA201590998A1 (en) 2016-02-29
NZ708349A (en) 2020-10-30
EA035559B1 (en) 2020-07-07
KR102210196B1 (en) 2021-02-01
IL238730B (en) 2019-12-31
JP6393270B2 (en) 2018-09-19
SG10201707488TA (en) 2017-10-30
WO2014081944A3 (en) 2014-07-17
JP7015223B2 (en) 2022-02-02
KR20150087340A (en) 2015-07-29
US9725497B2 (en) 2017-08-08
IL270852A (en) 2020-01-30
EP2922566A2 (en) 2015-09-30
US20210206825A1 (en) 2021-07-08
CN106977606B (en) 2021-08-27
ES2696148T3 (en) 2019-01-14
AU2020267284A1 (en) 2020-12-10
KR20210013324A (en) 2021-02-03
US20140155325A1 (en) 2014-06-05
IL238730A0 (en) 2015-06-30
UA118096C2 (en) 2018-11-26
AU2013347952A1 (en) 2015-05-28
MX2015006386A (en) 2015-12-03
AU2018241106B2 (en) 2020-08-20
EP2922566B1 (en) 2018-10-03
AU2013347952B2 (en) 2018-07-12
JP2019033748A (en) 2019-03-07
US20140155326A1 (en) 2014-06-05
US20170305997A1 (en) 2017-10-26
EP2922566A4 (en) 2016-10-26
NZ748444A (en) 2020-10-30
JP2022008534A (en) 2022-01-13
EP3485901B1 (en) 2021-10-13
IL270852B (en) 2020-09-30
US9695228B2 (en) 2017-07-04
CA2891485A1 (en) 2014-05-30
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AU2018241106A1 (en) 2018-10-25
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AU2020267284B2 (en) 2022-03-31
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JP2016504291A (en) 2016-02-12
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WO2014081944A2 (en) 2014-05-30

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